当前位置： SCI文献检索 > OPHTHALMOLOGY期刊下所有文献 > Conjunctival melanoma: outcomes based on tumor origin in 382 consecutive cases.

Conjunctival melanoma: outcomes based on tumor origin in 382 consecutive cases.

Abstract：

PURPOSE:To evaluate prognostic factors based on origin of conjunctival melanoma. DESIGN:Interventional case series. PARTICIPANTS:Three hundred eighty-two consecutive patients. METHODS:Retrospective chart review. MAIN OUTCOME MEASURES:Melanoma-related metastasis and death. RESULTS:The melanoma arose from primary acquired melanosis (PAM; n = 284; 74%), from pre-existing nevus (n = 26; 7%), and de novo (n = 72; 19%). The mean tumor base was 11 mm for melanoma arising from PAM, 6 mm for melanoma arising from nevus, and 10 mm for those arising de novo. At 5 years (10 years), melanoma metastasis occurred in 19% (25%) in melanoma arising from PAM (P = 0.003), 10% (26%) in melanoma from nevus (P = 0.193), and 35% (49%) in those de novo. Factors predictive of metastasis by multivariable analysis included tumor origin de novo (P = 0.001), palpebral location (P<0.001), nodular tumor (P = 0.005), and orbital invasion (P = 0.022). At 5 years (10 years), melanoma-related death occurred in 5% (9%) in melanoma arising from PAM (P<0.001), 0% (9%) in melanoma arising from nevus (P<0.057), and 17% (35%) in those arising de novo. Factors predictive of death by multivariable analysis included tumor origin de novo (P<0.001), fornix location (P = 0.04), and nodular tumor (P = 0.001). CONCLUSIONS:Melanoma arising de novo carries a higher risk of melanoma-related metastasis and death compared with those cases arising from PAM or nevus.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Shields CL,Markowitz JS,Belinsky I,Schwartzstein H,George NS,Lally SE,Mashayekhi A,Shields JA

doi

10.1016/j.ophtha.2010.06.021

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

389-95.e1-2

issue

2

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(10)00651-2

journal_volume

118

pub_type

杂志文章

相关文献

OPHTHALMOLOGY文献大全
  • Long-term outcomes of intraoperative 5-fluorouracil versus intraoperative mitomycin C in primary trabeculectomy surgery.

    abstract：OBJECTIVE:To compare the long-term efficacy of intraoperative 5-fluorouracil (5-FU) and mitomycin C (MMC) in primary trabeculectomy. DESIGN:Comparative case series and extension of a prospective, randomized controlled trial. PARTICIPANTS:One hundred fifteen eyes of 103 subjects undergoing primary trabeculectomy with ...

    journal_title：Ophthalmology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ophtha.2008.08.009

    authors： Palanca-Capistrano AM,Hall J,Cantor LB,Morgan L,Hoop J,WuDunn D

    更新日期：2009-02-01 00:00:00

  • Survey of 1264 patients with orbital tumors and simulating lesions: The 2002 Montgomery Lecture, part 1.

    abstract：OBJECTIVE:To determine the incidence of specific orbital tumors based on patients referred to an ocular oncology center. DESIGN:Retrospective, observational case series. PARTICIPANTS:A total of 1264 consecutive patients referred to an ocular oncology service because of space-occupying orbital lesions. METHODS:A retr...

    journal_title：Ophthalmology

    pub_type：

    doi：10.1016/j.ophtha.2003.01.002

    authors： Shields JA,Shields CL,Scartozzi R

    更新日期：2004-05-01 00:00:00

  • Transient increase in intraocular pressure during a dose-tapering regime of systemic dexamethasone in preterm infants.

    abstract：PURPOSE:To determine the intraocular pressure (IOP) profile during and after systemic dexamethasone treatment in preterm very low birth weight (VLBW; <1500 g) infants. DESIGN:A cohort study at a university-affiliated tertiary neonatal center. PARTICIPANTS:Twenty-seven VLBW infants who received a 3-week dose-tapering ...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2008.01.010

    authors： Ng PC,Lee CH,Tam BS,Wong SP,Lam HS,Kwok AK,Fok TF

    更新日期：2008-05-01 00:00:00

  • Threshold Amsler grid testing in maculopathies.

    abstract：:The Amsler grid is a suprathreshold target and thus may fail to detect relative scotomas. If the grid is viewed through two cross-polarizing filters creating low luminance conditions (threshold Amsler grid testing) the test is far more sensitive. Ten patients with disorders of the macula with normal standard white Ams...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(87)33315-9

    authors： Wall M,May DR

    更新日期：1987-09-01 00:00:00

  • Recovery of corneal sensitivity in grafts following penetrating keratoplasty.

    abstract：:Corneal sensitivity was tested in 145 cases of clear corneal transplants using Cochet-Bonnet aesthesiometer. The central area of corneal transplants was found to be either completely anesthetic or markedly hypesthetic even 32 years following corneal transplantation, as exemplified in a patient who had surgery for kera...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(85)33857-5

    authors： Rao GN,John T,Ishida N,Aquavella JV

    更新日期：1985-10-01 00:00:00

  • Treatment outcomes in malignant glaucoma.

    abstract：PURPOSE:To report treatment outcomes in malignant glaucoma. DESIGN:Retrospective case series. PARTICIPANTS:Twenty-eight eyes of 26 patients who were treated for malignant glaucoma between 1991 and 2009. METHODS:Malignant glaucoma was diagnosed based on the presence of a shallow or flat central and peripheral anterio...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2012.10.024

    authors： Dave P,Senthil S,Rao HL,Garudadri CS

    更新日期：2013-05-01 00:00:00

  • Large Disparities in Receipt of Glaucoma Care between Enrollees in Medicaid and Those with Commercial Health Insurance.

    abstract：PURPOSE:To determine whether the type of health insurance a patient possesses and a patient's race/ethnicity affect receipt of common tests to monitor open-angle glaucoma (OAG). DESIGN:Retrospective longitudinal cohort study. PARTICIPANTS:A total of 21 766 persons aged ≥40 years with newly diagnosed OAG between 2007 ...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2017.05.003

    authors： Elam AR,Andrews C,Musch DC,Lee PP,Stein JD

    更新日期：2017-10-01 00:00:00

  • Associations between health-related quality of life and the decision to perform surgery for childhood intermittent exotropia.

    abstract：OBJECTIVE:To assess associations between health-related quality of life (HRQOL) and the decision to perform strabismus surgery for children with intermittent exotropia. DESIGN:Retrospective chart review. PARTICIPANTS:Children with intermittent exotropia. METHODS:Included subjects, identified in a clinical practice, ...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2013.10.029

    authors： Hatt SR,Leske DA,Liebermann L,Mohney BG,Brodsky MC,Yamada T,Holmes JM

    更新日期：2014-04-01 00:00:00

  • Early vascular changes induced by transpupillary thermotherapy of choroidal neovascularization.

    abstract：OBJECTIVE:To study early direct effects of transpupillary thermotherapy (TTT) on choroidal neovascularization (CNV) and choroid. DESIGN:Retrospective, noncomparative interventional case series. PARTICIPANTS:Sixty-four eyes with subfoveal CNV. INTERVENTION:TTT was delivered using a diode laser at 810 nm through a con...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(02)01034-5

    authors： Lanzetta P,Michieletto P,Pirracchio A,Bandello F

    更新日期：2002-06-01 00:00:00

  • The onset and evolution of glaucomatous visual field defects.

    abstract：:Long-term follow-up was recorded on the visual fields of 251 patients with chronic open-angle glaucoma and 826 patients with ocular hypertension. Observation periods exceeded ten years for 73 patients with manifest glaucoma. Initial glaucomatous defects appeared in 98 eyes of 72 patients while under continuous observa...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(82)34798-3

    authors： Hart WM Jr,Becker B

    更新日期：1982-03-01 00:00:00

  • Prognostic factors in vitrectomy for epiretinal membranes of the macula.

    abstract：:A retrospective multivariate analysis of 264 consecutive cases of vitrectomy for removal of epiretinal membranes of the macula was performed. Two main preoperative prognostic factors were identified that were associated with the visual outcome of surgery: (1) the preoperative visual acuity, and (2) the duration of blu...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(86)33689-3

    authors： Rice TA,De Bustros S,Michels RG,Thompson JT,Debanne SM,Rowland DY

    更新日期：1986-05-01 00:00:00

  • Antibiotic resistance pattern and visual outcome in experimentally-induced Staphylococcus epidermidis endophthalmitis in a rabbit model.

    abstract：OBJECTIVE:To study whether the clinical outcome of Staphylococcus epidermidis-induced endophthalmitis in rabbits is related to the antibiotic resistance pattern of the infecting strain. DESIGN:Experimental animal study. PARTICIPANTS:The right eyes of 36 New Zealand white albino rabbits were inoculated with strains of...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(00)00545-5

    authors： Miño De Kaspar H,Hoepfner AS,Engelbert M,Thiel M,Ta CN,Mette M,Schulze-Schwering M,Grasbon T,Sesma-Vea B,Casas JM,Iturralde-Goñi R,Klauss V,Kampik A

    更新日期：2001-03-01 00:00:00

  • Prevalence and risk factors for age-related macular degeneration in an adult Japanese population: the Funagata study.

    abstract：OBJECTIVE:To describe the prevalence and risk factors for age-related macular degeneration (AMD) in a Japanese population and to compare these with data from a white population. DESIGN:Population-based cross-sectional epidemiologic study. PARTICIPANTS:A population-based sample of Japanese persons 35 years or older fr...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2007.11.015

    authors： Kawasaki R,Wang JJ,Ji GJ,Taylor B,Oizumi T,Daimon M,Kato T,Kawata S,Kayama T,Tano Y,Mitchell P,Yamashita H,Wong TY

    更新日期：2008-08-01 00:00:00

  • Nonarteritic anterior ischemic optic neuropathy: natural history of visual outcome.

    abstract：OBJECTIVE:To investigate systematically the natural history of visual outcome in nonarteritic anterior ischemic optic neuropathy (NAION). DESIGN:Cohort study. PARTICIPANTS:Three hundred forty consecutive untreated patients (386 eyes) with NAION, first seen in our clinic from 1973 to 2000. METHODS:At first visit, all...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2007.05.027

    authors： Hayreh SS,Zimmerman MB

    更新日期：2008-02-01 00:00:00

  • Complications of hydroxyapatite orbital implants. A review of 100 consecutive cases and a comparison of Dexon mesh (polyglycolic acid) with scleral wrapping.

    abstract：PURPOSE:The authors analyzed all the complications associates with the first 100 hydroxyapatite orbital implants performed by one surgeon, and compare scleral wrapping versus Dexon mesh (polyglycolic acid, Davis & Geck, Manati, Puerto Rico) wrapping in light of these complications. BACKGROUND:Prior studies have not in...

    journal_title：Ophthalmology

    pub_type： 杂志文章,评审

    doi：10.1016/s0161-6420(97)30316-9

    authors： Oestreicher JH,Liu E,Berkowitz M

    更新日期：1997-02-01 00:00:00

  • Cardiovascular disease and hypertension are strong risk factors for choroidal neovascularization.

    abstract：PURPOSE:To investigate the association of cardiovascular risk factors and inflammatory markers with neovascular age-related macular degeneration (AMD). DESIGN:Cross-sectional case-control study. PARTICIPANTS:Of the 410 of the >/=65-year-old community sample invited to attend, 205 participated (50% response rate). Of ...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2007.07.031

    authors： Hogg RE,Woodside JV,Gilchrist SE,Graydon R,Fletcher AE,Chan W,Knox A,Cartmill B,Chakravarthy U

    更新日期：2008-06-01 00:00:00

  • Sector-based analysis with the Heidelberg Retinal Tomograph 3 across disc sizes and glaucoma stages: a multicenter study.

    abstract：PURPOSE:To investigate the ability of sectorial analysis using the Heidelberg Retinal Tomograph 3 (HRT3) to discriminate between healthy and glaucomatous eyes and to determine whether this is affected by disc size and glaucoma severity. DESIGN:Multicenter, cross-sectional evaluation of diagnostic tests. PARTICIPANTS:...

    journal_title：Ophthalmology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ophtha.2009.01.020

    authors： Oddone F,Centofanti M,Iester M,Rossetti L,Fogagnolo P,Michelessi M,Capris E,Manni G

    更新日期：2009-06-01 00:00:00

  • Late diagnosis of choroidal malignant melanomas in eyes with clear media and low visual acuity.

    abstract：:Five patients seen in a one-year period with advanced malignant melanoma of the choroid in eyes with low visual acuity and clear media are reported. The low visual acuity appeared clinically to be antecedent to the malignant tumor; although in certain cases it may have been related to the occult melanoma, this was not...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(79)35423-9

    authors： Albert DM,Zakov ZN,Smith TR

    更新日期：1979-06-01 00:00:00

  • Prevalence of uncorrected binocular distance visual acuity in Hispanic and non-Hispanic adults. Results from the HHANES and the NHANES I.

    abstract：OBJECTIVE:This study aimed to provide a comparative analysis of American population-based prevalence of uncorrected binocular distance visual acuity in Hispanics and non-Hispanics. DESIGN:The study design was a population-based survey. PARTICIPANTS:Data from the Hispanic Health and Nutrition Examination Survey betwee...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/S0161-6420(98)93042-1

    authors： Lee DJ,Gomez-Marin O,Lam BL

    更新日期：1998-03-01 00:00:00

  • Ultrasound biomicroscopic configurations of the anterior ocular segment in a population-based study the Kumejima Study.

    abstract：PURPOSE:To characterize quantitatively the configuration of the anterior ocular segment with ultrasound biomicroscopy (UBM) in a population-based setting. DESIGN:Cross-sectional study. PARTICIPANTS:Ten percent of 4632 residents aged > or =40 years of Kumejima, an island off southwest Japan, were randomly selected. M...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2010.01.045

    authors： Henzan IM,Tomidokoro A,Uejo C,Sakai H,Sawaguchi S,Iwase A,Araie M

    更新日期：2010-09-01 00:00:00

  • Retinal detachment after branch retinal vein occlusion: influence of the type of break on the outcome of vitreous surgery.

    abstract：BACKGROUND:Branch retinal vein occlusion (BRVO) is occasionally complicated by two types of retinal breaks (retinal holes without vitreous traction or retinal traction tears) that may lead to a rhegmatogenous retinal detachment (RRD). The authors describe surgical results of vitrectomy for RRD after BRVO and investigat...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(97)30366-2

    authors： Ikuno Y,Tano Y,Lewis JM,Ikeda T,Sato Y

    更新日期：1997-01-01 00:00:00

  • Levobunolol. A beta-adrenoceptor antagonist effective in the long-term treatment of glaucoma. The Levobunolol Study Group (Appended).

    abstract：:We compared the ocular-hypotensive efficacy and systemic and ocular safety of an ophthalmic solution of levobunolol (0.5% and 1%) twice daily, with timolol (0.5%) twice daily in a long-term double-masked study of 391 patients with open-angle glaucoma or ocular hypertension. Patients received the test medication in bot...

    journal_title：Ophthalmology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：

    authors：

    更新日期：1985-09-01 00:00:00

  • Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus.

    abstract：PURPOSE:Ketorolac is a new, parenteral, nonsteroidal, anti-inflammatory agent. The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. METHODS:A prospective, randomized, d...

    journal_title：Ophthalmology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0161-6420(94)31238-3

    authors： Morrison NA,Repka MX

    更新日期：1994-05-01 00:00:00

  • Oculopalatal myoclonus after the one-and-a-half syndrome with facial nerve palsy.

    abstract：PURPOSE:The one-and-a-half syndrome is an eye movement disorder characterized by a unilateral gaze palsy and an ipsilateral internuclear ophthalmoplegia. The authors describe a previously unrecognized association between the one-and-a-half syndrome and oculopalatal myoclonus (OPM). METHODS:Five clinical cases are pres...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(96)30743-4

    authors： Wolin MJ,Trent RG,Lavin PJ,Cornblath WT

    更新日期：1996-01-01 00:00:00

  • Comparison of the Rotational Stability of Two Toric Intraocular Lenses in 1273 Consecutive Eyes.

    abstract：PURPOSE:To compare the rotational stability of the 2 most commonly used toric intraocular lenses (TIOLs). DESIGN:Retrospective cohort study in a single private practice. SUBJECTS:The study included all patients receiving an Acrysof (n = 626) or Tecnis TIOL (n = 647) over an 18-month period from April 2015 to Septembe...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/j.ophtha.2018.02.012

    authors： Lee BS,Chang DF

    更新日期：2018-09-01 00:00:00

  • Scheduled versus Pro Re Nata Dosing in the VIEW Trials.

    abstract：PURPOSE:To analyze visual acuity (VA) outcomes before and after preplanned treatment regimen change in the VIEW studies at week 52 (W52). DESIGN:Multiple post hoc analyses for retrospectively defined subgroups in 2 multicenter, multinational, double-masked trials. PARTICIPANTS:Two thousand four hundred fifty-seven ne...

    journal_title：Ophthalmology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ophtha.2015.08.014

    authors： Richard G,Monés J,Wolf S,Korobelnik JF,Guymer R,Goldstein M,Norenberg C,Sandbrink R,Zeitz O

    更新日期：2015-12-01 00:00:00

  • Initial 5-fluorouracil trabeculectomy in uncomplicated glaucoma.

    abstract：:The effectiveness of trabeculectomy with adjunctive low-dose 5-fluorouracil (5-FU) as the initial surgical procedure in uncomplicated glaucoma was evaluated retrospectively in a consecutive series of 52 patients (mean follow-up, 18.6 +/- 11.7 mos) and 74 control subjects. The cumulative 2-year success (intraocular pre...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(91)32180-8

    authors： Liebmann JM,Ritch R,Marmor M,Nunez J,Wolner B

    更新日期：1991-07-01 00:00:00

  • Automated scanning laser ophthalmoscope image montages of retinal diseases.

    abstract：PURPOSE:To generate wide-field automated seamless retinal montage images. DESIGN:Prospective, observational, case series study. PARTICIPANTS:Eighteen eyes of 14 patients were studied. INTERVENTION:A digital scanning laser ophthalmoscope (SLO), the Heidelberg Retina Angiograph (HRA), was used to obtain overlapping im...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/S0161-6420(99)90529-8

    authors： Rivero ME,Bartsch DU,Otto T,Freeman WR

    更新日期：1999-12-01 00:00:00

  • Posterior capsulectomy in pediatric cataract surgery: the necessity of a choice.

    abstract：OBJECTIVE:The purpose of the study is to evaluate whether a posterior capsulectomy combined with anterior vitrectomy is a necessity in pediatric cataract. DESIGN:The incidence of posterior capsule opacification, the need for additional surgical interventions, and the influence of a primary posterior capsulectomy after...

    journal_title：Ophthalmology

    pub_type： 杂志文章

    doi：10.1016/s0161-6420(97)30045-1

    authors： BenEzra D,Cohen E

    更新日期：1997-12-01 00:00:00

  • Baseline characteristics, the 25-Item National Eye Institute Visual Functioning Questionnaire, and their associations in the Complications of Age-Related Macular Degeneration Prevention Trial (CAPT).

    abstract：OBJECTIVE:To describe characteristics of participants in the Complications of Age-Related Macular Degeneration Prevention Trial (CAPT) at baseline and to investigate associations among visual function, fundus features, and vision-related quality of life. DESIGN:Cross-sectional study. PARTICIPANTS:The 1052 participant...

    journal_title：Ophthalmology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ophtha.2003.10.031

    authors： Maguire M,Complications of Age-Related Macular Degeneration Prevention Trial Research Group.

    更新日期：2004-07-01 00:00:00