Recovery of corneal sensitivity in grafts following penetrating keratoplasty.

Abstract:

:Corneal sensitivity was tested in 145 cases of clear corneal transplants using Cochet-Bonnet aesthesiometer. The central area of corneal transplants was found to be either completely anesthetic or markedly hypesthetic even 32 years following corneal transplantation, as exemplified in a patient who had surgery for keratoconus. Age, preoperative diagnosis, contact lens wear, diabetes, or length of postoperative period had no correlation with sensitivity in corneal grafts. In cases with a preoperative diagnosis of failed graft, even the peripheral recipient cornea was found to be relatively hypesthetic. The observations from this study that the central area of corneal graft never recovers normal sensitivity may have significant implications on the epithelial cell integrity of corneal grafts.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Rao GN,John T,Ishida N,Aquavella JV

doi

10.1016/s0161-6420(85)33857-5

subject

Has Abstract

pub_date

1985-10-01 00:00:00

pages

1408-11

issue

10

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(85)33857-5

journal_volume

92

pub_type

杂志文章
  • Low-Concentration Atropine for Myopia Progression (LAMP) Study: A Randomized, Double-Blinded, Placebo-Controlled Trial of 0.05%, 0.025%, and 0.01% Atropine Eye Drops in Myopia Control.

    abstract:PURPOSE:Low-concentration atropine is an emerging therapy for myopia progression, but its efficacy and optimal concentration remain uncertain. Our study aimed to evaluate the efficacy and safety of low-concentration atropine eye drops at 0.05%, 0.025%, and 0.01% compared with placebo over a 1-year period. DESIGN:Rando...

    journal_title:Ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ophtha.2018.05.029

    authors: Yam JC,Jiang Y,Tang SM,Law AKP,Chan JJ,Wong E,Ko ST,Young AL,Tham CC,Chen LJ,Pang CP

    更新日期:2019-01-01 00:00:00

  • Imaging of macular diseases with optical coherence tomography.

    abstract:BACKGROUND/PURPOSE:To assess the potential of a new diagnostic technique called optical coherence tomography for imaging macular disease. Optical coherence tomography is a novel noninvasive, noncontact imaging modality which produces high depth resolution (10 microns) cross-sectional tomographs of ocular tissue. It is ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(95)31032-9

    authors: Puliafito CA,Hee MR,Lin CP,Reichel E,Schuman JS,Duker JS,Izatt JA,Swanson EA,Fujimoto JG

    更新日期:1995-02-01 00:00:00

  • Ocular causes of abnormal head postures.

    abstract::A prospective study was undertaken to analyze the different causes of abnormal head postures on ocular bases. Eight basic mechanisms were found in a series of 188 patients. Incomitance accounted for 62.7% of the head postures and nystagmus for 20.2%. Important diagnostic criteria for evaluating patients with head post...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(79)35301-5

    authors: Kushner BJ

    更新日期:1979-12-01 00:00:00

  • Outcomes of surgical bleb revision for complications of trabeculectomy.

    abstract:OBJECTIVE:To describe the results of revision surgery for complications of trabeculectomy in a case series from an academic glaucoma service. DESIGN:Retrospective case series. PARTICIPANTS:A total of 177 eyes of 167 adult patients who underwent revision of trabeculectomy at the Wilmer Eye Institute between 1994 and 2...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.04.003

    authors: Radhakrishnan S,Quigley HA,Jampel HD,Friedman DS,Ahmad SI,Congdon NG,McKinnon S

    更新日期:2009-09-01 00:00:00

  • Prospective evaluation of radial keratotomy. Photokeratoscope corneal topography.

    abstract::Preoperative and postoperative corneascope photographs of 368 myopic patients undergoing radial keratotomy in the Prospective Evaluation of Radial Keratotomy (PERK) study were optically scanned and digitized. A high-resolution scanning system was developed in order to quantify the preoperative and postoperative cornea...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(88)33179-9

    authors: Rowsey JJ,Balyeat HD,Monlux R,Holladay J,Waring GO 3rd,Lynn MJ

    更新日期:1988-03-01 00:00:00

  • Microsporidial keratoconjunctivitis in a healthy contact lens wearer without human immunodeficiency virus infection.

    abstract:PURPOSE:To present a rare case of microsporidial keratoconjunctivitis in an otherwise healthy contact lens wearer without human immunodeficiency virus infection who responded to treatment with systemic albendazole and topical fumagillin. DESIGN:Interventional case report. METHOD:A cornea epithelial scraping from a ma...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(01)00542-5

    authors: Theng J,Chan C,Ling ML,Tan D

    更新日期:2001-05-01 00:00:00

  • Different Factors Associated with 2-Year Outcomes in Patients with Branch versus Central Retinal Vein Occlusion Treated with Ranibizumab.

    abstract:PURPOSE:To investigate characteristics associated with visual and anatomic outcomes in branch and central retinal vein occlusion (BRVO and CRVO) patients treated with ranibizumab. DESIGN:Post hoc analysis of patients with BRVO and CRVO from 2 multicenter clinical trials who completed month 12 of the HORIZON extension ...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2019.07.018

    authors: Sophie R,Wang PW,Channa R,Quezada-Ruiz C,Clark A,Campochiaro PA

    更新日期:2019-12-01 00:00:00

  • Retinal and choroidal biopsies are helpful in unclear uveitis of suspected infectious or malignant origin.

    abstract:OBJECTIVES:To assess the clinical value of retinal or choroidal biopsy in establishing a definitive diagnosis directing subsequent management and to assess the risk involved in such surgery. DESIGN:Retrospective noncomparative interventional case series. PARTICIPANTS:Thirteen patients with uveitis of suspected malign...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2002.10.002

    authors: Johnston RL,Tufail A,Lightman S,Luthert PJ,Pavesio CE,Cooling RJ,Charteris D

    更新日期:2004-03-01 00:00:00

  • The normal age-corrected and reaction time-corrected isopter derived by semi-automated kinetic perimetry.

    abstract:PURPOSE:To determine the increase in isopter extent, resulting from the measurement of, and correction for, individual reaction time (RT; the latency between stimulus presentation and individual patient response), derived under the standardized conditions of semi-automated kinetic perimetry (SKP), and to model the age-...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2006.09.030

    authors: Vonthein R,Rauscher S,Paetzold J,Nowomiejska K,Krapp E,Hermann A,Sadowski B,Chaumette C,Wild JM,Schiefer U

    更新日期:2007-06-01 00:00:00

  • The California syndrome. Functional visual complaints with potential economic impact.

    abstract::The records of 84 patients with functional visual loss (59 adults and 25 children) were reviewed over a six-year period. The patients were between 7 and 69 years of age. In the young patients, psychosocial problems relating to parental divorce, poor school performance and attention-getting behavior were common, while ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Keltner JL,May WN,Johnson CA,Post RB

    更新日期:1985-03-01 00:00:00

  • In vivo laser confocal microscopy findings for Bowman's layer dystrophies (Thiel-Behnke and Reis-Bücklers corneal dystrophies).

    abstract:OBJECTIVE:To investigate microstructures in patients with genetically confirmed Bowman's layer dystrophies (Thiel-Behnke or Reis-Bücklers corneal dystrophy) using an in vivo laser scanning confocal microscope. DESIGN:Single-center, prospective, comparative small case series. PARTICIPANTS:Two patients from one pedigre...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2006.05.076

    authors: Kobayashi A,Sugiyama K

    更新日期:2007-01-01 00:00:00

  • Eyelid involvement in multicentric reticulohistiocytosis.

    abstract:CASE REPORT:The authors report the first biopsy-confirmed ocular adnexal involvement by multicentric reticulohistiocytosis. The patient was a 28-year-old black woman with a 15-year history of well-documented multicentric reticulohistiocytosis who had multiple dermal nodules and severe mutilating arthritis that had prod...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(95)31005-6

    authors: Eagle RC Jr,Penne RA,Hneleski IS Jr

    更新日期:1995-03-01 00:00:00

  • Effect of topical trifluridine on Thygeson's superficial punctate keratitis.

    abstract::Six eyes of four patients with Thygeson's superficial punctate keratitis were treated with trifluridine 1% drops. Five of the six treated eyes responded favorably to topical trifluridine therapy. Symptoms and later the signs of the disease disappeared, but more slowly than observed following topical corticosteroid the...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34170-7

    authors: Nesburn AB,Lowe GH 3rd,Lepoff NJ,Maguen E

    更新日期:1984-10-01 00:00:00

  • Macular pigment optical density in a midwestern sample.

    abstract:OBJECTIVE:To assess the distribution of the macular pigments (MPs) lutein (L) and zeaxanthin (Z) in a healthy sample more representative of the general population than past studies and to determine which dietary factors and personal characteristics might explain the large interindividual differences in the density of t...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(00)00655-2

    authors: Ciulla TA,Curran-Celantano J,Cooper DA,Hammond BR Jr,Danis RP,Pratt LM,Riccardi KA,Filloon TG

    更新日期:2001-04-01 00:00:00

  • Visual function in prolactinoma patients treated with bromocriptine.

    abstract::Ten patients with prolactin-secreting pituitary adenomas (prolactinoma) and visual dysfunction were treated primarily with bromocriptine. Nine patients had improvement of visual field or acuity associated with computed tomography (CT) evidence of a decrease in tumor size and reduction of serum prolactin level (SPL). V...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(85)33853-8

    authors: Moster ML,Savino PJ,Schatz NJ,Snyder PJ,Sergott RC,Bosley TM

    更新日期:1985-10-01 00:00:00

  • A comparison of the Marcus Gunn and alternating light tests for afferent pupillary defects.

    abstract:OBJECTIVE:The authors compared two methods, the Marcus Gunn test and the alternating light test, for detecting a relative afferent pupillary defect. DESIGN:A randomized, prospective clinical trial. PARTICIPANTS:Fourteen patients with unilateral optic neuropathy. INTERVENTION:The Marcus Gunn and alternating light tes...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/S0161-6420(98)95029-1

    authors: Enyedi LB,Dev S,Cox TA

    更新日期:1998-05-01 00:00:00

  • The onset and evolution of glaucomatous visual field defects.

    abstract::Long-term follow-up was recorded on the visual fields of 251 patients with chronic open-angle glaucoma and 826 patients with ocular hypertension. Observation periods exceeded ten years for 73 patients with manifest glaucoma. Initial glaucomatous defects appeared in 98 eyes of 72 patients while under continuous observa...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(82)34798-3

    authors: Hart WM Jr,Becker B

    更新日期:1982-03-01 00:00:00

  • A prospective evaluation of a diffractive versus a refractive designed multifocal intraocular lens.

    abstract:OBJECTIVE:To evaluate prospectively a diffractive (811E, Pharmacia; power add +4.0 D) versus a refractive (PA154N, Allergan; power add +3.5 D) designed multifocal lens. PARTICIPANTS:Eighty patients planned for cataract surgery without additional ocular pathologies were randomized into the diffractive or refractive gro...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(97)30127-4

    authors: Walkow T,Liekfeld A,Anders N,Pham DT,Hartmann C,Wollensak J

    更新日期:1997-09-01 00:00:00

  • Riboflavin and ultraviolet light a therapy as an adjuvant treatment for medically refractive Acanthamoeba keratitis: report of 3 cases.

    abstract:PURPOSE:To present the first 3 cases of Acanthamoeba keratitis (AK), unresponsive to medical treatment, that were successfully treated with a novel adjunctive therapy using ultraviolet light A (UVA) and riboflavin (B2). DESIGN:Interventional case series. PARTICIPANTS:Two patients with confirmed AK and 1 patient with ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2010.06.041

    authors: Khan YA,Kashiwabuchi RT,Martins SA,Castro-Combs JM,Kalyani S,Stanley P,Flikier D,Behrens A

    更新日期:2011-02-01 00:00:00

  • A novel hereditary developmental vitreoretinopathy with multiple ocular abnormalities localizing to a 5-cM region of chromosome 5q13-q14.

    abstract:BACKGROUND:To undertake a clinical and molecular analysis of a previously unpublished kindred with a phenotypically distinct vitreoretinopathy characterized by associated ocular developmental abnormalities. DESIGN:Family genetic study. PARTICIPANTS:A total of 23 members, both affected and unaffected, of 1 kindred wit...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(99)90486-4

    authors: Black GC,Perveen R,Wiszniewski W,Dodd CL,Donnai D,McLeod D

    更新日期:1999-11-01 00:00:00

  • Fundus Tessellation: Prevalence and Associated Factors: The Beijing Eye Study 2011.

    abstract:PURPOSE:To examine the prevalence of fundus tessellation and its associated factors. DESIGN:Population-based study. PARTICIPANTS:The Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6±9.8 years (range, 50-93 years). METHODS:Participants underwent a comprehensive ophthalmic examination. By using...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2015.05.031

    authors: Yan YN,Wang YX,Xu L,Xu J,Wei WB,Jonas JB

    更新日期:2015-09-01 00:00:00

  • Performance of frequency-doubling technology perimetry in a population-based prevalence survey of glaucoma: the Tajimi study.

    abstract:OBJECTIVE:To evaluate the performance of frequency-doubling technology (FDT) perimetry in a population-based glaucoma prevalence survey. DESIGN:Population-based cross-sectional study. PARTICIPANTS:Participants older than 40 years randomly selected from the population of Tajimi City. METHODS:Each participant underwen...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2006.06.041

    authors: Iwase A,Tomidokoro A,Araie M,Shirato S,Shimizu H,Kitazawa Y,Tajimi Study Group.

    更新日期:2007-01-01 00:00:00

  • Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration.

    abstract:OBJECTIVE:Two similarly designed, phase-3 studies (VEGF Trap-Eye: Investigation of Efficacy and Safety in Wet AMD [VIEW 1, VIEW 2]) of neovascular age-related macular degeneration (AMD) compared monthly and every-2-month dosing of intravitreal aflibercept injection (VEGF Trap-Eye; Regeneron, Tarrytown, NY, and Bayer He...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2012.09.006

    authors: Heier JS,Brown DM,Chong V,Korobelnik JF,Kaiser PK,Nguyen QD,Kirchhof B,Ho A,Ogura Y,Yancopoulos GD,Stahl N,Vitti R,Berliner AJ,Soo Y,Anderesi M,Groetzbach G,Sommerauer B,Sandbrink R,Simader C,Schmidt-Erfurth U,VIE

    更新日期:2012-12-01 00:00:00

  • Comparisons of methods to detect glaucomatous optic nerve damage.

    abstract:PURPOSE:Various techniques of optic disc and nerve fiber layer evaluation may be used to detect structural glaucomatous damage. The authors compared several qualitative and quantitative methods to determine their relative sensitivities and specificities to detect the presence of glaucomatous visual field loss. METHODS...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(93)31450-8

    authors: O'Connor DJ,Zeyen T,Caprioli J

    更新日期:1993-10-01 00:00:00

  • Characteristics of immune rejection after allogeneic cultivated limbal epithelial transplantation.

    abstract:PURPOSE:To investigate the characteristics and prognosis of immune rejection after allogeneic cultivated limbal epithelial transplantation (CLET). DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Forty-two eyes of 41 patients undergoing allogeneic CLET for total limbal stem cell deficiency who completed...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.11.001

    authors: Qi X,Xie L,Cheng J,Zhai H,Zhou Q

    更新日期:2013-05-01 00:00:00

  • Quality of nonmydriatic digital fundus photography obtained by nurse practitioners in the emergency department: the FOTO-ED study.

    abstract:OBJECTIVE:Nonmydriatic fundus photography by non-ophthalmic-trained personnel has recently been shown to be a potential alternative to direct ophthalmoscopy in the emergency department (ED). We evaluated the reliability of a novel quality rating scale and applied this scale to nonmydriatic fundus photographs taken duri...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2011.09.013

    authors: Lamirel C,Bruce BB,Wright DW,Delaney KP,Newman NJ,Biousse V

    更新日期:2012-03-01 00:00:00

  • Polyclonal orbital and systemic infiltrates.

    abstract::Two unusual cases of benign lymphoproliferative disease associated with orbital and systemic involvement are described. Both have occurred in adults with longstanding histories and clinical manifestations that have mimicked lymphomas. The orbital disease has been both antecedent and subsequent to the systemic lesions....

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34189-6

    authors: Rootman J,Patel S,Jewell L

    更新日期:1984-09-01 00:00:00

  • Evaluation of the lacrimal drainage system.

    abstract::Methods of testing for lacrimal drainage insufficiency and a modification of the Jones fluorescein dye tests are presented. Despite their excellence, Jones tests have never been widely employed because of difficulty in dye retrieval. The modification consists of instilling one drop of the dye three times at 15 second ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(78)35559-7

    authors: Hecht SD

    更新日期:1978-12-01 00:00:00

  • Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.

    abstract:PURPOSE:To report the long-term outcomes of patients with iridocorneal endothelial (ICE) syndrome who required surgery for glaucoma. DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Twenty-six patients with ICE syndrome who underwent surgery for glaucoma at one institution between January 1987 and Janua...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(01)00725-4

    authors: Doe EA,Budenz DL,Gedde SJ,Imami NR

    更新日期:2001-10-01 00:00:00

  • A method for ipsilateral rotational autokeratoplasty.

    abstract::Rotational ipsilateral penetrating autokeratoplasty is useful in the treatment of certain nonprogressive corneal scars. The procedure alleviates difficulties with the availability of donor tissue and with graft rejection. A method is presented for determining the maximum clear central corneal area that can be obtained...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(78)35561-5

    authors: Bourne WM,Brubaker RF

    更新日期:1978-12-01 00:00:00