Iris melanomas. Diagnostic problems.

abstract：PURPOSE:To develop a universal gene therapy to overcome the genetic heterogeneity in retinitis pigmentosa (RP) resulting from mutations in rhodopsin (RHO). DESIGN:Experimental study for a combination gene therapy that uses both gene ablation and gene replacement. PARTICIPANTS:This study included 2 kinds of human RHO ...

journal_title：Ophthalmology

authors： Tsai YT,Wu WH,Lee TT,Wu WP,Xu CL,Park KS,Cui X,Justus S,Lin CS,Jauregui R,Su PY,Tsang SH

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Porous coralline hydroxyapatite orbital implants have gained significant popularity for use in anophthalmic sockets. Several reports have noted increased rates of early implant exposure. METHODS:Six patients with exposure complications of primary hydroxyapatite implants after enucleation or evisceration wer...

journal_title：Ophthalmology

authors： Kim YD,Goldberg RA,Shorr N,Steinsapir KD

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:The purpose of the study is to determine safety and efficacy outcomes of excimer laser photorefractive keratectomy (PRK) for the treatment of mild-to-moderate myopia. DESIGN:A prospective, multicenter, phase III clinical trial. PARTICIPANTS:A total of 701 eyes of 701 patients were entered in the study; 612 ...

journal_title：Ophthalmology

authors： Hersh PS,Stulting RD,Steinert RF,Waring GO 3rd,Thompson KP,O'Connell M,Doney K,Schein OD

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:The purpose of the study was to determine the predictors of success and evaluate the use of perfluoroperhydrophenanthrene as an intraoperative and postoperative tool in the management of giant retinal tears in a multicentered collaborative study. DESIGN:Multicentered prospective case series. PARTICIPANTS:Tw...

journal_title：Ophthalmology

authors： Kertes PJ,Wafapoor H,Peyman GA,Calixto N Jr,Thompson H

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Behçet disease is a chronic, recurrent, inflammatory disorder characterized by the triad of oral and genital ulcers and ocular lesions. The etiology is unknown. Although many of these patients become blind, some have good vision all their life. METHODS:To attain more accurate data on the prognosis of these ...

journal_title：Ophthalmology

authors： Sakamoto M,Akazawa K,Nishioka Y,Sanui H,Inomata H,Nose Y

更新日期：1995-02-01 00:00:00

abstract：:A CW YAG laser was used to coagulate retina and to produce an optical iridotomy in a human eye that was to be enucleated for malignant melanoma at the optic nerve head. Moderate coagulation with the CW YAG laser produced a deep choroidal reaction involving the outer portion of the retina. The inner structure of the fo...

journal_title：Ophthalmology

authors： Peyman GA,Larson B

更新日期：1984-09-01 00:00:00

abstract：PURPOSE:To use optical coherence tomography (OCT) to evaluate the femtosecond laser intrastromal incisions made during cataract surgery to reduce corneal astigmatism. DESIGN:Retrospective case series. PARTICIPANTS:Seventy-seven eyes of 77 patients. METHODS:Paired intrastromal incisions were created using the Catalys...

journal_title：Ophthalmology

authors： Wang L,Jiang L,Hallahan K,Al-Mohtaseb ZN,Koch DD

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To determine whether the abducens nerve is present in patients with type 2 Duane's retraction syndrome (DRS). DESIGN:Retrospective, observational case series. PARTICIPANTS:Twelve consecutive patients diagnosed with type 2 DRS. METHODS:A retrospective review of medical records of ophthalmologic examination ...

journal_title：Ophthalmology

authors： Kim JH,Hwang JM

更新日期：2012-02-01 00:00:00

abstract：:The authors studied the hospital records of 453 patients who underwent primary surgical repair of penetrating ocular injuries at the Wilmer Institute from January 1970 through December 1981. The injury was due to blunt force in 22%, a sharp laceration in 37%, and a missile in 41%. The following factors correlated with...

journal_title：Ophthalmology

authors： De Juan E Jr,Sternberg P Jr,Michels RG

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:To investigate whether interleukin (IL)-6 or vascular endothelial growth factor (VEGF) influences macular edema in patients with central retinal vein occlusion (CRVO). DESIGN:Retrospective case-control study. PARTICIPANTS:Twenty-seven patients who had macular edema with CRVO and 16 patients with nonischemic...

journal_title：Ophthalmology

authors： Noma H,Funatsu H,Mimura T,Harino S,Hori S

更新日期：2009-01-01 00:00:00

abstract：:Twelve patients with hypereosinophilic syndrome were studied to determine the frequency and type of eye involvement in this systemic disease. Four patients (33%) had visual symptoms, including blurred vision in one or both eyes, and one patient had an episode of complete blindness following cardiac surgery. Five patie...

journal_title：Ophthalmology

authors： Chaine G,Davies J,Kohner EM,Hawarth S,Spry CJ

更新日期：1982-12-01 00:00:00

abstract：:The authors used the Humphrey Retinal Analyzer to study the effect of acute changes in intraocular pressure (IOP) on the topography of the optic nerve head in normotensive and hypertensive eyes of cynomolgus monkeys. Chronically elevated IOP was produced monocularly in monkeys by argon laser angle treatment. In 8 hype...

journal_title：Ophthalmology

authors： Coleman AL,Quigley HA,Vitale S,Dunkelberger G

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:Visual acuity (VA) is the primary outcome measure in many studies involving eye diseases. A standard statistical approach for comparing a continuous measurement such as a VA letter score between 2 treatment groups is to perform a t test comparing the means. However, frequently a binary variable is created from ...

journal_title：Ophthalmology

authors： Beck RW,Maguire MG,Bressler NM,Glassman AR,Lindblad AS,Ferris FL

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:The purpose of this study is to determine if an endoscope would improve visualization of the anterior chamber angle and facilitate goniotomy in a surgical cloudy corneal model of primary infantile glaucoma. METHODS:A 23-gauge needle coupled to a 0.8-mm diameter flexible endoscope entered the anterior chamber o...

journal_title：Ophthalmology

authors： Joos KM,Alward WL,Folberg R

更新日期：1993-07-01 00:00:00

abstract：:Warburg syndrome is a congenital oculocerebral disorder. It is caused by a genetic defect that simultaneously affects ocular and cerebral embryogenesis. The characteristic ophthalmic findings reflect the cerebral malformation (agyria or lissencephaly). Two cases, siblings, have been described. The characteristic bilat...

journal_title：Ophthalmology

authors： Levine RA,Gray DL,Gould N,Pergament E,Stillerman ML

更新日期：1983-12-01 00:00:00

abstract：:An ultrasound diagnostic coding system was developed that permitted entry of diagnoses into a programmable calculator, thus permitting rapid information retrieval of patients with a specific diagnosis or diagnoses as well as the number of patients with a specific diagnosis. Cataract, vitreous opacity, trauma, choroida...

journal_title：Ophthalmology

authors： Frank KE,Purnell EW,Jennings WD

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Dapsone is used widely in treating ocular cicatricial pemphigoid, leprosy, and dermatologic disorders. Hemolysis is a well-known complication of dapsone therapy. Rarely, neutropenia or agranulocytosis may occur, resulting in up to a 50% mortality rate. To the authors' knowledge, agranulocytosis has not been ...

journal_title：Ophthalmology

authors： Raizman MB,Fay AM,Weiss JS

更新日期：1994-11-01 00:00:00

abstract：:A retrospective multivariate analysis of 264 consecutive cases of vitrectomy for removal of epiretinal membranes of the macula was performed. Two main preoperative prognostic factors were identified that were associated with the visual outcome of surgery: (1) the preoperative visual acuity, and (2) the duration of blu...

journal_title：Ophthalmology

authors： Rice TA,De Bustros S,Michels RG,Thompson JT,Debanne SM,Rowland DY

更新日期：1986-05-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of a reading rehabilitation program (RRP) specifically designed for patients with impaired central vision from age-related macular degeneration (AMD) and the impact of the program on the quality of life (QoL) and to determine any predictable reading performance improvements between visi...

journal_title：Ophthalmology

authors： Coco-Martín MB,Cuadrado-Asensio R,López-Miguel A,Mayo-Iscar A,Maldonado MJ,Pastor JC

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:To evaluate the clinical features, treatment, and prognosis of patients with uveal metastasis from lung cancer. DESIGN:Retrospective chart review. PARTICIPANTS:There were 194 patients with a diagnosis of uveal metastasis from lung cancer. INTERVENTION:Radiotherapy, chemotherapy, enucleation, or observation. ...

journal_title：Ophthalmology

authors： Shah SU,Mashayekhi A,Shields CL,Walia HS,Hubbard GB 3rd,Zhang J,Shields JA

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:A prospective study was conducted to investigate the corneal shape changes due to scleral buckling surgery. These changes were analyzed based on the type of buckling procedures performed. METHODS:A total of 89 eyes from 88 patients were stratified into four groups based on the type of buckling procedures used,...

journal_title：Ophthalmology

authors： Hayashi H,Hayashi K,Nakao F,Hayashi F

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To study early direct effects of transpupillary thermotherapy (TTT) on choroidal neovascularization (CNV) and choroid. DESIGN:Retrospective, noncomparative interventional case series. PARTICIPANTS:Sixty-four eyes with subfoveal CNV. INTERVENTION:TTT was delivered using a diode laser at 810 nm through a con...

journal_title：Ophthalmology

authors： Lanzetta P,Michieletto P,Pirracchio A,Bandello F

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To document the long-term effect of argon laser peripheral iridoplasty (ALPI) in eyes with plateau iris syndrome. DESIGN:Retrospective, noncomparative, interventional case series. SETTING:New York Eye and Ear Infirmary. METHODS:The charts of all patients with plateau iris syndrome treated with ALPI from 19...

journal_title：Ophthalmology

authors： Ritch R,Tham CC,Lam DS

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To investigate the associations of serum amyloid A (SAA) protein and soluble tumor necrosis factor receptors 1 and 2 (sTNF-R1 and sTNF-R2) with diabetic retinopathy (DR) in Hispanics. DESIGN:Prospective, nonrandomized, cross-sectional, family-based observational cohort study. PARTICIPANTS:A total of 473 Hispa...

journal_title：Ophthalmology

authors： Kuo JZ,Guo X,Klein R,Klein BE,Cui J,Rotter JI,Ipp E,Chen YD

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To report the clinical and pathologic features of sarcomatous transformation of the skull with involvement of the orbit, in Paget's disease. DESIGN:Interventional case report. PARTICIPANT:An 83-year-old woman with Paget's disease who experienced progressive proptosis of the left eye. INTERVENTION:Fine-need...

journal_title：Ophthalmology

authors： Goldberg S,Slamovits TL,Dorfman HD,Rosenbaum PS

更新日期：2000-08-01 00:00:00

abstract：:In a controlled, nonrandomized, longitudinal cohort study, we studied the efficacy of systemic immunosuppression in treatment of progressive cicatricial pemphigoid affecting the eyes. Twenty-six patients were studied; 18 received systemic immunosuppressive drugs, and eight received conventional therapy. Three patients...

journal_title：Ophthalmology

authors： Foster CS,Wilson LA,Ekins MB

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:To assess associations between the stages of age-related maculopathy (ARM) and dietary intake of carotene, vitamin C, retinol, and zinc. DESIGN:Cross-sectional, population-based study. PARTICIPANTS:A total of 3654 subjects 49 years of age and older from a defined area, west of Sydney, Australia, participate...

journal_title：Ophthalmology

authors： Smith W,Mitchell P,Webb K,Leeder SR

更新日期：1999-04-01 00:00:00

abstract：PURPOSE:The existence of genetic variations in a number of cytokines has been considered to influence susceptibility or relate to disease severity in various autoimmune diseases. Among these, single-nucleotide polymorphisms (SNPs) of the tumor necrosis factor alpha (TNF-alpha) promoter at nucleotides -308 and -238 are ...

journal_title：Ophthalmology

authors： El-Shabrawi Y,Wegscheider BJ,Weger M,Renner W,Posch U,Ulrich S,Ardjomand N,Hermann J

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:To evaluate the visual outcome, number of injections, and direct medical cost of a "treat and extend" regimen (TER) in managing neovascular age-related macular degeneration (nAMD) with intravitreal ranibizumab. DESIGN:Retrospective, interventional, consecutive case series. PARTICIPANTS:Ninety-two eyes of 92 p...

journal_title：Ophthalmology

authors： Gupta OP,Shienbaum G,Patel AH,Fecarotta C,Kaiser RS,Regillo CD

更新日期：2010-11-01 00:00:00

abstract：:A clinicopathologic study of multiple extramacular drusen (MED) was performed on 784 eyes of 412 consecutive autopsies and on 100 eyes of 50 consecutive patients with MED. The clinical and histopathologic characteristics of MED and its correlation with reticular degeneration of the pigment epithelium (RDPE) and with m...

journal_title：Ophthalmology

authors： Lewis H,Straatsma BR,Foos RY

更新日期：1986-08-01 00:00:00