Experimental endoscopic goniotomy. A potential treatment for primary infantile glaucoma.

Abstract:

PURPOSE:The purpose of this study is to determine if an endoscope would improve visualization of the anterior chamber angle and facilitate goniotomy in a surgical cloudy corneal model of primary infantile glaucoma. METHODS:A 23-gauge needle coupled to a 0.8-mm diameter flexible endoscope entered the anterior chamber of porcine cadaver eyes through a corneal incision near the limbus. Internal structures were observed on a videoscreen and recorded as the needle approached and incised pectinate ligaments near Schwalbe's line. The eyes were then prepared for light microscopy and scanning electron microscopy. RESULTS:Internal structures were clearly visualized on the videoscreen during the goniotomy. The incision of pectinate ligaments was accompanied by the iris falling back and opening of the trabecular meshwork compared with the untreated portion of the angle. This was confirmed histopathologically. CONCLUSIONS:An endoscope coaxially coupled to a goniotomy needle tip allows visualization of the anterior chamber angle during goniotomy in the pig despite the presence of a cloudy cornea. The porcine anterior chamber angle is a useful animal model for studying the surgical treatment of primary infantile glaucoma.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Joos KM,Alward WL,Folberg R

subject

Has Abstract

pub_date

1993-07-01 00:00:00

pages

1066-70

issue

7

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(93)31537-X

journal_volume

100

pub_type

杂志文章
  • Human corneal anatomy redefined: a novel pre-Descemet's layer (Dua's layer).

    abstract:PURPOSE:To define and characterize a novel pre-Descemet's layer in the human cornea. DESIGN:Clinical and experimental study. PARTICIPANTS:We included 31 human donor sclerocorneal discs, including 6 controls (mean age, 77.7 years). METHODS:Air was injected into the stroma of donor whole globes (n = 4) and sclerocorne...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2013.01.018

    authors: Dua HS,Faraj LA,Said DG,Gray T,Lowe J

    更新日期:2013-09-01 00:00:00

  • Retinal detachment after cataract surgery. Predisposing factors.

    abstract::The authors studied the characteristics of 376 eyes of 361 patients with primary retinal detachment (RD) and surgical aphakia (103 eyes) or pseudophakia (273 eyes). Of the pseudophakic eyes, 17 had an iris-fixated intraocular lens (IOL), 111 had an anterior chamber (AC) IOL, and 145 had a posterior chamber (PC) IOL. O...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(92)31953-0

    authors: Yoshida A,Ogasawara H,Jalkh AE,Sanders RJ,McMeel JW,Schepens CL

    更新日期:1992-03-01 00:00:00

  • Primary transpupillary thermotherapy for small choroidal melanoma in 256 consecutive cases: outcomes and limitations.

    abstract:OBJECTIVE:The objective of this report was to evaluate ocular and systemic outcomes after primary transpupillary thermotherapy for choroidal melanoma and to identify the limitations of this treatment method. DESIGN:Noncomparative interventional case series. PARTICIPANTS:The participants included 256 patients with new...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(01)00902-2

    authors: Shields CL,Shields JA,Perez N,Singh AD,Cater J

    更新日期:2002-02-01 00:00:00

  • Pathology of corneal hydrogel alloplastic implants.

    abstract::Hydrogel keratophakia is a new form of lamellar refractive surgery which, in theory, can deal with almost all forms of refractive error. We examined the histopathological effects of several types of hydrogel materials on the cornea of non-human primates. With the exception of one type of hydrogel material, which was a...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(85)33869-1

    authors: Peiffer RL,Werblin TP,Fryczkowski AW

    更新日期:1985-09-01 00:00:00

  • Biomicroscopy of papillae associated with hard contact lens wearing.

    abstract::We studied the macrostructural characteristics of papillary changes of the upper tarsal conjunctiva associated with the wearing of polymethyl methacrylate (PMMA) contact lenses. Fifty subjects with elevated conjunctival papillae greater than 0.3 mm in diameter were studied. Macrostructural characteristics recorded wer...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(81)34899-4

    authors: Korb DR,Allansmith MR,Greiner JV,Henriquez AS,Herman JP,Richmond PP,Finnemore VM

    更新日期:1981-11-01 00:00:00

  • Toxocara canis infestation. Clinical and epidemiological associations with seropositivity in kindergarten children.

    abstract::We studied a cohort of 333 children in kindergarten to determine the prevalence of seropositivity to Toxocara canis, and to detect and measure chronic health effects that might be attributable to past infection. We found that 23.1% of the children had serologic evidence of infection (antibody titer greater than or equ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(86)33625-x

    authors: Ellis GS Jr,Pakalnis VA,Worley G,Green JA,Frothingham TE,Sturner RA,Walls KW

    更新日期:1986-08-01 00:00:00

  • Responsiveness and clinically important differences for the VF-14 index, SF-36, and visual acuity in patients undergoing cataract surgery.

    abstract:OBJECTIVE:To assess visual acuity (VA) and 2 questionnaires of health-related quality of life--the Visual Function 14 (VF-14) index and the Medical Outcomes Study Short Form 36 Health Survey (SF-36)--as instruments for capturing clinically important changes after cataract surgery. DESIGN:Prospective, observational stu...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ophtha.2008.11.020

    authors: Bilbao A,Quintana JM,Escobar A,García S,Andradas E,Baré M,Elizalde B,IRYSS-Cataract Group.

    更新日期:2009-03-01 00:00:00

  • Long-term trends in glaucoma-related blindness in Olmsted County, Minnesota.

    abstract:OBJECTIVE:To determine the longitudinal trends in the probability of blindness due to open-angle glaucoma (OAG) in Olmsted County, Minnesota, from 1965 to 2009. DESIGN:Retrospective, population-based cohort study. PARTICIPANTS:All residents of Olmsted County, Minnesota (aged ≥ 40 years) who were diagnosed with OAG be...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2013.09.003

    authors: Malihi M,Moura Filho ER,Hodge DO,Sit AJ

    更新日期:2014-01-01 00:00:00

  • Implementation of a free cataract surgery program in rural China: a community-based randomized interventional study.

    abstract:PURPOSE:To identify effective methods to increase the number of cataract surgeries in a rural setting in Pucheng County of Shaanxi Province, northwestern China. DESIGN:Community-based randomized interventional study. PARTICIPANTS:Four hundred thirty-two patients 50 years of age or older with operable cataract who had...

    journal_title:Ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ophtha.2012.07.087

    authors: Zhang XJ,Liang YB,Liu YP,Jhanji V,Musch DC,Peng Y,Zheng CR,Zhang HX,Chen P,Tang X,Lam DS

    更新日期:2013-02-01 00:00:00

  • Narrowing of the retinal arterioles in descending optic atrophy. A quantitative clinical study.

    abstract::Measurements were made on fundus photographs of the diameters of retinal arterioles in a series of cases with various nonvascular lesions of the anterior visual pathways, before and after the development of fundus signs of optic atrophy. A simple method was devised for reliable estimation of the diameter of the centra...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34144-6

    authors: Frisén L,Claesson M

    更新日期:1984-11-01 00:00:00

  • Optic neuropathy after vitrectomy for retinal detachment: clinical features and analysis of risk factors.

    abstract:PURPOSE:To describe the clinical characteristics of and risk factors for the development of optic neuropathy after pars plana vitrectomy (PPV) for macula-sparing primary rhegmatogenous retinal detachment (RRD) repair. DESIGN:Retrospective case-control study. PARTICIPANTS:Seven patients who underwent PPV for macula-sp...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.06.002

    authors: Bansal AS,Hsu J,Garg SJ,Sivalingam A,Vander JF,Moster M,Maguire JI,Regillo CD

    更新日期:2012-11-01 00:00:00

  • Melanotic neuroectodermal tumor of infancy (retinal anlage tumor).

    abstract::Six cases of the melanotic neuroectodermal tumor of infancy, including light and electron microscopic findings, are presented. The tumor, now believed to originate from neural crest, is usually cured by wide excision; however, malignant cases have been reported. Histopathologically, this lesion resembles neural retina...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(85)34080-0

    authors: Lamping KA,Albert DM,Lack E,Dickersin GR,Chapman PH,Walton DS

    更新日期:1985-01-01 00:00:00

  • Familial corneal scarring: a new dystrophy?

    abstract::A 34-year-old white man with skin manifestations of the epidermal nevus syndrome was found to have anesthetic corneas, dry eyes, and localized opaque nodular elevations of both corneas. Similar corneal lesions, unassociated with corneal anesthesia, were found in four family members. Histology of corneal biopsies from ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34320-2

    authors: Hirst LW,Farmer ER,Green WR,Silver A,Walsh FB

    更新日期:1984-02-01 00:00:00

  • Lipemic diabetic retinopathy.

    abstract::A study group of eight patients with diabetic retinopathy and marked accumulation of hard exudates in the fundi is described. There was a significant increase in serum triglyceride levels (P less than 0.05) in the study group as compared to a control group of 23 consecutive patients with diabetic retinopathy. This exu...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34098-2

    authors: Brown GC,Ridley M,Haas D,Lucier AC,Sarin LK

    更新日期:1984-12-01 00:00:00

  • Proliferative vitreoretinopathy. Lymphocytes in epiretinal membranes.

    abstract:BACKGROUND:To investigate the potential contribution of inflammatory and immune-mediated processes contributing to the pathogenesis of proliferative vitreoretinopathy (PVR), an immunohistochemical study was undertaken to characterize the infiltrating inflammatory cells in epiretinal membranes surgically removed from th...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(92)31793-2

    authors: Charteris DG,Hiscott P,Grierson I,Lightman SL

    更新日期:1992-09-01 00:00:00

  • Drusen with accompanying fluid underneath the sensory retina.

    abstract:PURPOSE:To investigate whether confluent drusen may be accompanied by fluid accumulation underneath the sensory retina and to determine if the detection of subretinal fluid on spectral-domain optical coherence tomography (OCT) in patients with coalescent drusen is indicative of choroidal neovascularization (CNV). DESI...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2010.04.017

    authors: Sikorski BL,Bukowska D,Kaluzny JJ,Szkulmowski M,Kowalczyk A,Wojtkowski M

    更新日期:2011-01-01 00:00:00

  • Clinical spectrum of diffuse infiltrating retinoblastoma in 34 consecutive eyes.

    abstract:PURPOSE:To evaluate the clinical features and management of diffuse infiltrating retinoblastoma. DESIGN:Retrospective case series. PARTICIPANTS:Thirty-four eyes in 32 patients. METHODS:The patients' records were reviewed for patient and tumor features, ocular management, histopathologic findings, and patient surviva...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2008.07.003

    authors: Shields CL,Ghassemi F,Tuncer S,Thangappan A,Shields JA

    更新日期:2008-12-01 00:00:00

  • Retinal detachment after branch retinal vein occlusion: influence of the type of break on the outcome of vitreous surgery.

    abstract:BACKGROUND:Branch retinal vein occlusion (BRVO) is occasionally complicated by two types of retinal breaks (retinal holes without vitreous traction or retinal traction tears) that may lead to a rhegmatogenous retinal detachment (RRD). The authors describe surgical results of vitrectomy for RRD after BRVO and investigat...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(97)30366-2

    authors: Ikuno Y,Tano Y,Lewis JM,Ikeda T,Sato Y

    更新日期:1997-01-01 00:00:00

  • Follow-up of transnasal orbital decompression in severe Graves' ophthalmopathy.

    abstract:OBJECTIVE:To evaluate the safety and efficacy of transnasal orbital decompression for severe Graves' ophthalmopathy. DESIGN:Retrospective noncomparative case series with extended clinical follow-up. PARTICIPANTS:Seventy-eight consecutive subjects who were operated on for compressive optic neuropathy with loss of visu...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(00)00533-9

    authors: Michel O,Oberländer N,Neugebauer P,Neugebauer A,Rüssmann W

    更新日期:2001-02-01 00:00:00

  • Three-year results of Artisan/Verisyse phakic intraocular lens implantation. Results of the United States Food And Drug Administration clinical trial.

    abstract:OBJECTIVE:To assess the safety and efficacy of the Artisan/Verisyse phakic intraocular lens (IOL) for the correction of high myopia. DESIGN:Prospective, open-label, noncomparative, multicenter clinical trial. PARTICIPANTS:A total of 684 adults with axial myopia from -4.5 diopters (D) to -22 D were enrolled: 662 in th...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ophtha.2007.08.039

    authors: Stulting RD,John ME,Maloney RK,Assil KK,Arrowsmith PN,Thompson VM,U.S. Verisyse Study Group.

    更新日期:2008-03-01 00:00:00

  • The management of giant retinal tears using perfluoroperhydrophenanthrene. A multicenter case series. Vitreon Collaborative Study Group.

    abstract:OBJECTIVE:The purpose of the study was to determine the predictors of success and evaluate the use of perfluoroperhydrophenanthrene as an intraoperative and postoperative tool in the management of giant retinal tears in a multicentered collaborative study. DESIGN:Multicentered prospective case series. PARTICIPANTS:Tw...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/s0161-6420(97)30168-7

    authors: Kertes PJ,Wafapoor H,Peyman GA,Calixto N Jr,Thompson H

    更新日期:1997-07-01 00:00:00

  • Macular versus Retinal Nerve Fiber Layer Parameters for Diagnosing Manifest Glaucoma: A Systematic Review of Diagnostic Accuracy Studies.

    abstract:TOPIC:Macular parameters have been proposed as an alternative to retinal nerve fiber layer (RNFL) parameters to diagnose glaucoma. Comparing the diagnostic accuracy of macular parameters, specifically the ganglion cell complex (GCC) and ganglion cell inner plexiform layer (GCIPL), with the accuracy of RNFL parameters f...

    journal_title:Ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ophtha.2015.12.041

    authors: Oddone F,Lucenteforte E,Michelessi M,Rizzo S,Donati S,Parravano M,Virgili G

    更新日期:2016-05-01 00:00:00

  • Ophthalmic evaluation of survivors of acute lymphoblastic leukemia.

    abstract::Eighty-two survivors of acute lymphoblastic leukemia (ALL) had prospective eye evaluations to determine the ocular sequelae of the disease and its treatment. All patients had completed or nearly completed a 25- to 31-month protocol which included either 3.4 or 10.2 g of systemic prednisone/m2 per year and cranial irra...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(88)33198-2

    authors: Hoover DL,Smith LE,Turner SJ,Gelber RD,Sallan SE

    更新日期:1988-02-01 00:00:00

  • Oral acyclovir in the therapy of acute herpes zoster ophthalmicus. An interim report.

    abstract::A prospective, randomized, double-masked, placebo-controlled clinical trial was conducted to study the effects of oral acyclovir on 55 patients with acute herpes zoster ophthalmicus. Treatment with oral acyclovir resulted in more prompt resolution of signs and symptoms, particularly in patients treated within 72 hours...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(85)33842-3

    authors: Cobo LM,Foulks GN,Liesegang T,Lass J,Sutphin J,Wilhelmus K,Jones DB,Chapman S,Segreti A

    更新日期:1985-11-01 00:00:00

  • Intraocular pressure control and complications with two-stage insertion of the Baerveldt implant.

    abstract:PURPOSE:To evaluate intraocular pressure (IOP) control and the prevalence of complications associated with the two-stage insertion of the Baerveldt implant. DESIGN:Retrospective, noncomparative, interventional case series. METHODS:We reviewed the medical records of all patients who underwent the two-stage Baerveldt i...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(02)01752-9

    authors: Tong L,Frazao K,LaBree L,Varma R

    更新日期:2003-02-01 00:00:00

  • Effect of marihuana on intraocular and blood pressure in glaucoma.

    abstract::Marihuana inhalation was accompanied by increased heart rate and decreased intraocular and blood pressure in 18 subjects with heterogenous glaucomas. The hypotensive effects appeared in 60 to 90 minutes as the decrease in intraocular pressure (IOP) appeared to follow the decrease in blood pressure. In addition to any ...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(80)35258-5

    authors: Merritt JC,Crawford WJ,Alexander PC,Anduze AL,Gelbart SS

    更新日期:1980-03-01 00:00:00

  • The relation of cardiovascular disease and its risk factors to the 5-year incidence of age-related maculopathy: the Beaver Dam Eye Study.

    abstract:OBJECTIVE:The purpose of the study is to examine the association between cardiovascular disease and its risk factors and the incidence of age-related maculopathy. PARTICIPANTS:A population of 3583 adults (range, 43-86 years of age at baseline) living in Beaver Dam, Wisconsin, was studied at baseline and 5 years later....

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(97)30023-2

    authors: Klein R,Klein BE,Jensen SC

    更新日期:1997-11-01 00:00:00

  • A new classification of superior oblique palsy based on congenital variations in the tendon.

    abstract:BACKGROUND:Superior oblique palsy is the most frequent isolated cranial nerve palsy seen in strabismus practice. It is traditionally diagnosed according to etiology as acquired, congenital, or idiopathic, but surgical treatment is based on deviation not etiology. Observations at surgery led to speculation that the supe...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(92)31759-2

    authors: Helveston EM,Krach D,Plager DA,Ellis FD

    更新日期:1992-10-01 00:00:00

  • Outcomes of cataract extraction with multifocal intraocular lens implantation: functional status and quality of life.

    abstract:OBJECTIVE:The authors measured functional status after bilateral implantation of a multifocal versus a monofocal intraocular lens (IOL). METHODS:A retrospective, case-control study was done on 100 subjects implanted bilaterally with a silicone-optic foldable zonal progressive IOL under United States Food and Drug Admi...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(97)30265-6

    authors: Javitt JC,Wang F,Trentacost DJ,Rowe M,Tarantino N

    更新日期:1997-04-01 00:00:00

  • Adverse intraoperative medical events and their association with anesthesia management strategies in cataract surgery.

    abstract:OBJECTIVE:To compare adverse medical events by different anesthesia strategies for cataract surgery. DESIGN:Prospective cohort study. PARTICIPANTS:Patients 50 years of age and older undergoing 19,250 cataract surgeries at nine centers in the United States and Canada between June 1995 and June 1997. INTERVENTION:Loca...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0161-6420(01)00704-7

    authors: Katz J,Feldman MA,Bass EB,Lubomski LH,Tielsch JM,Petty BG,Fleisher LA,Schein OD,Study of Medical Testing for Cataract Surgery Study Team.

    更新日期:2001-10-01 00:00:00