Changes in retinal nerve fiber layer thickness after reduction of intraocular pressure in chronic open-angle glaucoma.

Abstract:

PURPOSE:The authors evaluated the relative nerve fiber layer height changes in glaucomatous eyes after reduction of intraocular pressure (IOP) after trabeculectomy using image analysis techniques. METHODS:Optic disc topography and relative nerve fiber layer height of 12 eyes of 12 patients with chronic open-angle glaucoma were measured using a Rodenstock optic nerve head analyzer and Caprioli's program for nerve fiber layer height determination before trabeculectomy and at 2 or more months after surgery. RESULTS:Changes in relative nerve fiber layer height after surgery, as well as those in cup volume and rim area, showed statistically significant correlation with the degree of reduction of IOP (Spearman's correlation coefficient = 0.66; P < 0.05). Changes in the mean deviation of Humphrey visual field showed a slight correlation with IOP reduction (Spearman's correlation coefficient = 0.55; P < 0.1). CONCLUSION:Nerve fiber layer height changes that may occur after trabeculectomy are pressure-dependent.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Sogano S,Tomita G,Kitazawa Y

doi

10.1016/s0161-6420(93)31497-1

subject

Has Abstract

pub_date

1993-08-01 00:00:00

pages

1253-8

issue

8

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(93)31497-1

journal_volume

100

pub_type

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