A double-blind trial of tamoxifen plus prednisolone versus tamoxifen plus placebo in postmenopausal women with metastatic breast cancer. A collaborative trial of the North Central Cancer Treatment Group and Mayo Clinic.

abstract：BACKGROUND:This multicenter, retrospective study explored the value of oncogene driver subtype, programmed death-1 ligand (PD-L1) status, and smoking status for predicting which patients with oncogene-driven non-small cell lung cancer (NSCLC) would benefit from treatment with programmed death-1 (PD-1)/PD-L1 inhibitors....

journal_title：Cancer

authors： Ng TL,Liu Y,Dimou A,Patil T,Aisner DL,Dong Z,Jiang T,Su C,Wu C,Ren S,Zhou C,Camidge DR

更新日期：2019-04-01 00:00:00

abstract：:Of the remote effects of cancer on the neurologic system, paraneoplastic cerebellar degeneration (PCD), characterized by global cerebellar dysfunction, is second only to paraneoplastic neuropathies in frequency. Recent evidence, including the finding of anti-Purkinje cell (now termed anti-Yo) antibodies directed again...

journal_title：Cancer

authors： Waterhouse DM,Natale RB,Cody RL

更新日期：1991-10-15 00:00:00

abstract：:Massachusetts vital event data for 1969--1972 were used to develop correlations between mortality rates for malignant diseases and other causes of death over the 34 health planning subdivisions of the state. A significant correlation was found between the mortality rates for cancer of the colon and rectum and ischemic...

journal_title：Cancer

authors： Lipworth LL,Rice CA

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Prognostic factors for patients with stage III melanoma are still controversial. METHODS:Two hundred eighty-six patients with solitary cutaneous malignant melanoma of the skin in Stage III (International Union Against Cancer [UICC]) were followed up for as long as 11 years. RESULTS:Patients in risk group p...

journal_title：Cancer

authors： Drepper H,Biess B,Hofherr B,Hundeiker M,Lippold A,Otto F,Padberg G,Peters A,Wiebelt H

更新日期：1993-02-15 00:00:00

abstract：BACKGROUND:There is increasing evidence that radiation therapy (RT) can be omitted for select older patients who are compliant with hormonal blockade, but there is no recent claim-based analysis for determining patterns of care and guiding possible treatment recommendations. METHODS:Medicare beneficiaries who were 65 ...

journal_title：Cancer

authors： Wallace AS,Keene KS,Williams CP,Jackson BE,Pisu M,Partridge EE,Rocque GB

更新日期：2018-02-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a frequent complication of cancer and cancer treatment and is associated with multiple clinical consequences, including recurrent VTE, bleeding, and an increase in the risk of death. Although the risks associated with VTE have been well recognized in surgical cancer patients, there is a...

journal_title：Cancer

authors： Lyman GH

更新日期：2009-12-15 00:00:00

abstract：:The accumulation of large amounts of fluid in the pleural space is a common sequela of disseminated carcinomatosis. Traditional management has included therapeutic thoracentesis or the placement of a large bore chest tube for drainage with the subsequent installation of a sclerosing agent in an attempt to achieve pleu...

journal_title：Cancer

authors： Parker LA,Charnock GC,Delany DJ

更新日期：1989-09-15 00:00:00

abstract：:The presentation, growth patterns, and response to therapy of 11 consecutive children with choroid plexus carcinomas were analyzed, and the results were compared with the outcome reported in other series. Patients were a median of 26 months of age at diagnosis. Two patients had thalamic tumors, one had a posterior fos...

journal_title：Cancer

authors： Packer RJ,Perilongo G,Johnson D,Sutton LN,Vezina G,Zimmerman RA,Ryan J,Reaman G,Schut L

更新日期：1992-01-15 00:00:00

abstract：BACKGROUND:Cisplatin has been reported to enhance the cell-killing effect of radiation. The current study was conducted to evaluate the efficacy and toxicity of radiotherapy combined with cisplatin in patients with locally advanced pancreatic carcinoma. METHODS:Forty-one patients with pancreatic carcinoma that was unr...

journal_title：Cancer

authors： Okusaka T,Okada S,Tokuuye K,Wakasugi H,Saisho H,Ishikawa O,Matsuno S,Sato T,Sato K,Non-surgical Treatment Group for Pancreatic Cancer in Japan.

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Non-Hodgkin lymphoma (NHL), the most common cancer of the lymphatic system, is of unknown etiology. The identification of etiologic factors in the onset of NHL is a key event that could facilitate the prevention and cure of this malignancy. Simian virus 40 (SV40) has been considered an oncogenic agent in the...

journal_title：Cancer

authors： Tognon M,Luppi M,Corallini A,Taronna A,Barozzi P,Rotondo JC,Comar M,Casali MV,Bovenzi M,D'Agostino A,Vinante F,Rigo A,Ferrarini I,Barbanti-Brodano G,Martini F,Mazzoni E

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate changes in clinical and pathologic characteristics of prostate cancer in patients who underwent surgery at a large tertiary care center in the context of increased use of active surveillance (AS) and minimally invasive surgery (MIS). METHODS:The authors retrospect...

journal_title：Cancer

authors： Silberstein JL,Vickers AJ,Power NE,Fine SW,Scardino PT,Eastham JA,Laudone VP

更新日期：2011-11-01 00:00:00

abstract：:A case of primary non-Hodgkin's lymphoma of the breast was studied with light and electron microscopy and for immunologic cell markers. With light microscopy, the tumor was seen to be a poorly differentiated lymphocytic lymphoma, diffuse, according to Rappaport's classification. With electron microscopy, the tumor was...

journal_title：Cancer

authors： Tateno M,Yoshiki T,Itoh T,Takamuro M,Saito C

更新日期：1983-08-15 00:00:00

abstract：:Mesenchymal chondrosarcoma, an uncommon lesion of bone and extraskeletal tissue, is rare in the orbit. A case of extraskeletal mesenchymal chondrosarcoma of the orbit in a 28-year-old woman presenting with proptosis and diminution of vision in the left eye is reported. Histologically, the tumor showed areas of undiffe...

journal_title：Cancer

authors： Bagchi M,Husain N,Goel MM,Agrawal PK,Bhatt S

更新日期：1993-10-01 00:00:00

abstract：:The presence of receptors for estrogen, glucocorticoid and progesterone was determined in the cytosol of two breast angiosarcomas. Estrogen and glucocorticoid receptors were present in both of them. Progesterone receptors were present in one of the two tumors assayed. Occupied nuclear estrogen receptors have been foun...

journal_title：Cancer

authors： Brentani MM,Pacheco MM,Oshima CT,Nagai MA,Lemos LB,Góes JC

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Widespread disparities in care have been documented in women with gynecologic cancer in the United States. This study was designed to determine whether structural barriers to optimal care were present during the preoperative period for patients with gynecologic cancer. METHODS:A retrospective review was con...

journal_title：Cancer

authors： Frey MK,Moss HA,Musa F,Rolnitzky L,David-West G,Chern JY,Boyd LR,Curtin JP

更新日期：2016-03-15 00:00:00

abstract：BACKGROUND:Little is known about cellular level genetic alterations in preinvasive breast lesions, particularly lobular carcinoma in situ. METHODS:We employed fluorescence in situ hybridization (FISH) using pericentromeric (alpha satellite) probes to assess numerical alterations of chromosomes 1, 7, 8, 16, 17, and X i...

journal_title：Cancer

authors： Visscher DW,Wallis TL,Crissman JD

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:Renal medullary carcinoma is a rare tumor that is most common in young black men with sickle cell disease or trait. Patients often present with advanced disease at the time of diagnosis, and their prognosis is poor, even with aggressive therapy. The clinical and pathologic features of renal medullary carcino...

journal_title：Cancer

authors： Assad L,Resetkova E,Oliveira VL,Sun W,Stewart JM,Katz RL,Caraway NP

更新日期：2005-02-25 00:00:00

abstract：:The interferon (IFN) assay of the sera from the 40 patients with head and neck cancer was performed by the plaque-reduction assay with vesicular stomatitis virus in FL cells derived from human amniotic membrane. The patients mainly had Stage III or IV lesion without distant metastasis, and previously had not received ...

journal_title：Cancer

authors： Sato M,Yoshida H,Yanagawa T,Yura Y,Urata M,Atsumi M,Furumoto N,Hayashi Y,Takegawa Y

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:The recommended phase 2 dose (RP2D) of anticancer agents is determined traditionally by dose-limiting toxicities. Nontoxicity or biological endpoints such as pharmacokinetics, pharmacodynamics, and efficacy can also be used to identify RP2D, which may be relevant to molecularly targeted agents (MTAs). METHO...

journal_title：Cancer

authors： Hansen AR,Cook N,Amir E,Siu LL,Abdul Razak AR

更新日期：2017-04-15 00:00:00

abstract：BACKGROUND:Metastatic renal cell cancer is associated with poor long-term survival and has no cure. Traditional clinical endpoints are best supplemented by patient-reported outcomes designed to assess symptoms and function. Normative data was obtained on the National Comprehensive Cancer Network-Functional Assessment o...

journal_title：Cancer

authors： Butt Z,Peipert J,Webster K,Chen C,Cella D

更新日期：2013-01-15 00:00:00

abstract：:Although clinically evident thyroid carcinoma is not a frequent neoplasm (incidence 2.7 per 100,000 persons in La Plata, Argentina), occult carcinomas are present in a high proportion of the population, but there are marked differences along geographical lines. The purpose of the present study is to establish the prev...

journal_title：Cancer

authors： Ottino A,Pianzola HM,Castelletto RH

更新日期：1989-07-15 00:00:00

abstract：:Both cytogenetic analysis and flow cytometry (FCM) have prognostic efficacy in the analysis of transitional cell carcinoma (TCC) of urinary bladder. To correlate results of the two methods, we studied a unique group of patients whose tumors had undergone prospective conventional cytogenetic analysis. Paraffin blocks o...

journal_title：Cancer

authors： Coon JS,Schwartz D,Summers JL,Miller AW 3rd,Weinstein RS

更新日期：1986-04-15 00:00:00

abstract：BACKGROUND:There are currently no systemic treatments for stage IV melanoma, which have been proven in randomized trials to benefit overall survival (OS). Lenalidomide has efficacy against melanoma in animal models and safety in phase 1 trials. The authors reported the results of a phase 2/3 study comparing the safety ...

journal_title：Cancer

authors： Glaspy J,Atkins MB,Richards JM,Agarwala SS,O'Day S,Knight RD,Jungnelius JU,Bedikian AY

更新日期：2009-11-15 00:00:00

abstract：:This study is based on 38 patients, each of whom had a malignant lymphoma in which the gonad was the site of the main tumor mass at the time of diagnosis. Histiocytic lymphoma was the predominant type in the 27 male patients; in the 11 female patients, poorly differentiated lymphocytic lymphoma was the most frequent t...

journal_title：Cancer

authors： Paladugu RR,Bearman RM,Rappaport H

更新日期：1980-02-01 00:00:00

abstract：:A 55-year-old man is reported who initially developed chronic lymphocytic leukemia. Seven years later, after chemotherapy with chlorambucil, chronic myelogenous leukemia was diagnosed in addition to the chronic lymphocytic leukemia. Four previously reported cases with the same sequence of events are reviewed as well a...

journal_title：Cancer

authors： Schreiber ZA,Axelrod MR,Abebe LS

更新日期：1984-08-15 00:00:00

abstract：:For men diagnosed with clinically localized prostate cancer, definitive therapy with radical prostatectomy, external beam radiation therapy, or brachytherapy offers a high chance of cure. Currently, there are insufficient data to recommend 1 treatment approach over another, leaving physicians and patients to decide ba...

journal_title：Cancer

authors： Nguyen CT,Zelefsky MJ,Kattan MW

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to clarify the significance of p21WAF1/CIP1(p21) gene expression in the tumorgenicity of hepatitis B virus (HBV) and hepatitis C virus (HCV) infected human hepatocelluar carcinoma (HCC). METHODS:The authors performed Northern blot hybridization to compare the p21 mess...

journal_title：Cancer

authors： Kobayashi S,Matsushita K,Saigo K,Urashima T,Asano T,Hayashi H,Ochiai T

更新日期：2001-06-01 00:00:00

abstract：:Clinical, histological and ultrastructural features of three small cell carcinomas arising in the parotid gland are presented. The light microscopic appearance of two of the neoplasms suggested neuroendocrine cell derivation, confirmed by electron microscopy in both instances. The fine structure of the third neoplasm ...

journal_title：Cancer

authors： Kraemer BB,Mackay B,Batsakis JG

更新日期：1983-12-01 00:00:00

abstract：:Tumor-associated antigens (TAA) excreted into the urine of sarcoma patients can be detected by the complement-fixation assay. The authors prospectively measured TAA levels in the urine of 50 sarcoma patients postoperatively to determine whether reappearance of antigen in the urine would be predictive of disease recurr...

journal_title：Cancer

authors： Huth JF,Gupta RK,Eilber FR,Morton DL

更新日期：1984-03-15 00:00:00

abstract：BACKGROUND:The authors administered a combination of docetaxel and topotecan with granulocyte-colony-stimulating factor (G-CSF) support in a Phase I study to define the maximum tolerated dose (MTD) of this regimen. METHODS:Patients with advanced-stage solid tumors were eligible for this trial if they had a Zubrod perf...

journal_title：Cancer

authors： Tsao AS,Shin DM,Palmer JL,Lee JS,Glisson BS

更新日期：2004-05-15 00:00:00