Abstract：
:In robotic and conventional minimally invasive surgery the risk of complications caused by collateral tissue damage remains high. This paper studies the concept of imposing damage thresholds on surgical instruments to avoid tissue overload. More specifically, the correlation between mechanical loading and damage in case of vascular clamping is investigated. With a computer controlled device, a high and a low clamping load were applied in vivo on the abdominal aorta of 43 rats. Samples of both loading levels were compared with zero load control samples and with samples clamped by a mosquito clamp w.r.t. functionality and histological integrity. Analysis of the samples shows that high clamping forces result in endothelial and smooth muscle cell destruction. Clamping with a mosquito clamp will cause even more damage to the elastic lamellae. Samples loaded at the lower load showed significantly less smooth muscle cell damage and a lower degree of endothelial damage. This paper is the first to statistically quantify the correlation between the degree of mechanical loading and the degree of tissue damage, thus setting the first steps towards tissue overload prevention during surgery. Future experiments will also include the effects of loading duration, recovery and patient-specificity.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Famaey N,Verbeken E,Vinckier S,Willaert B,Herijgers P,Vander Sloten Jdoi
10.1016/j.medengphy.2010.04.002subject
Has Abstractpub_date
2010-06-01 00:00:00pages
437-43issue
5eissn
1350-4533issn
1873-4030pii
S1350-4533(10)00076-7journal_volume
32pub_type
杂志文章abstract：:Terahertz pulsed imaging is a spectroscopic imaging modality using pulses of electromagnetic radiation (100 GHz-10 THz), and there has been recent interest in studying biomedical specimens. It is usual to display parametric images derived from the measured pulses. In this work, classification was achieved by applying ...
journal_title：Medical engineering & physics
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journal_title：Medical engineering & physics
pub_type： 杂志文章,评审
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更新日期：2019-04-01 00:00:00
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更新日期：2004-12-01 00:00:00
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