Abstract：
:Tripolar nerve cuff electrodes have been widely used for measuring peripheral nerve activity. However, despite the high signal-to-noise ratio levels that can be achieved with this recording configuration, the clinical use of cuff electrodes in closed-loop controlled neuroprostheses remains limited. This is largely attributed to artifact noise signals that contaminate the recorded neural activity. In this study, we investigated the use of a conductive shield layer (CSL) as a means of reducing the artifact noise recorded by nerve cuff electrodes. Using both computational simulations and in vivo experiments, we found that the CSL can result in up to an 85% decrease in the recorded artifact signal. Both the electrical conductivity and the surface area of the CSL were identified as important design criteria. Although this study shows that the CSL can significantly reduce artifact noise in tripolar nerve cuff electrodes, long-term implant studies are needed to validate our findings.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Sabetian P,Sadeghlo B,Zhang CH,Yoo PBdoi
10.1016/j.medengphy.2016.11.010subject
Has Abstractpub_date
2017-02-01 00:00:00pages
39-46eissn
1350-4533issn
1873-4030pii
S1350-4533(16)30291-0journal_volume
40pub_type
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