Abstract：
:Image-based finite element modelling has been commonly used to determine the biomechanical behaviours of human femora, particularly for the diagnosis of femoral head necrosis. One of the fundamental aspects of biomechanical modelling is the relationship between bone density, which is obtained from images, and elastic modulus. While there exist some empirical equations relating density with elastic modulus, the characterization of this relationship remains incomplete, especially for necrotic femoral heads. The objective of this study was to determine the relationship between density and elastic modulus by combining ultrasonic scanning and computed tomography (CT). Bone specimens were surgically removed from the femora of eight persons (seven females and one male in the age range of 55-68 years old) and underwent both ultrasonic and CT scanning. The images were processed with MATLAB scripts, and a bilinear interpolation algorithm was used to determine the relationship between the CT-measured densities and ultrasound-measured elastic moduli. The results showed different density-elastic modulus relations between the hardening strap of the necrotic region and non-hardening strap areas of the necrotic region. The uniqueness of this study is the characterization of mechanical properties (in the present study, the density-modulus relationship) from clinical images, which would be valuable in computational biomechanics used for the diagnosis and treatment evaluation of femoral head necrosis.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Yue Y,Yang H,Li Y,Zhong H,Tang Q,Wang J,Wang R,He H,Chen W,Chen Ddoi
10.1016/j.medengphy.2019.02.002subject
Has Abstractpub_date
2019-04-01 00:00:00pages
12-17eissn
1350-4533issn
1873-4030pii
S1350-4533(19)30023-2journal_volume
66pub_type
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