Abstract:
:A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of esomeprazole and domperidone. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths, 301 nm and 284 nm, lambda max of esomeprazole and domperidone respectively. Beer's law was obeyed in the concentration range of 5-20 mug/ml and 8-30 mug/ml for esomeprazole and domperidone respectively. The method was found to be precise, accurate, and specific. The proposed method was successfully applied to estimation of esomeprazole and domperidone in combined solid dosage form.
journal_name
Indian J Pharm Scijournal_title
Indian journal of pharmaceutical sciencesauthors
Prabu SL,Shirwaikar A,Shirwaikar A,Kumar CD,Joseph A,Kumar Rdoi
10.4103/0250-474X.40351subject
Has Abstractpub_date
2008-01-01 00:00:00pages
128-31issue
1eissn
0250-474Xissn
1998-3743journal_volume
70pub_type
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