A Chromatographic Determination of Aripiprazole using HPLC and UPLC: A Comparative Validation Study.

abstract：:Various (4-substituted) phenyl-3-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]propionylamido-1,3-thiazolidine-4-ones (3a-x) and 1-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]-propionylamido-3-chloro-4-(4-substituted)phenyl-azetidin-2-ones (4a-x) have been synthesised by the cyclocondensation of ...

journal_title：Indian journal of pharmaceutical sciences

authors： Desai SR,Laddi UV,Bennur RS,Bennur SC

更新日期：2011-07-01 00:00:00

abstract：:A simple, precise, accurate and rapid high performance thin layer chromatographic method has been developed and validated for the estimation of tenoxicam in the microemulsion gels. Tenoxicam was chromatographed on silica gel 60 F(254) TLC plate, as a stationary phase. The mobile phase was toluene: ethyl acetate: formi...

journal_title：Indian journal of pharmaceutical sciences

authors： Chandel S,Barhate CR,Srivastava AR,Kulkarni SR,Kapadia CJ

更新日期：2012-01-01 00:00:00

abstract：:Recent studies have shown that gallic acid and its alkylesters induce apoptosis in different cell lines. Since new compounds with biological activity and less cytotoxicity to normal cells are necessary for cancer therapy, the aim of this study was to evaluate the cytotoxic effect of 1-(3,4,5-trihydroxyphenyl)-dodecylb...

journal_title：Indian journal of pharmaceutical sciences

authors： Maioral MF,Bubniak LD,Marzarotto MA,De Moraes AC,Leal P,Nunes R,Yunes RA,Santos-Silva MC

更新日期：2016-01-01 00:00:00

abstract：:A simple and sensitive spectrofluorimetric method has been developed for the estimation of brimonidine tartrate in pure and eye drops. Linearity was obeyed in the range of 0.2-3.0 ΅g/ml in dimethyl formamide as solvent at an emission wavelength (λem) of 530 nm after excitation wavelength (λex) of 389 nm with good corr...

journal_title：Indian journal of pharmaceutical sciences

authors： Sunitha G,Bhagirath R,Alapati VR,Ramakrishna K,Subrahmanyam CV,Anumolu PD

更新日期：2013-11-01 00:00:00

abstract：:In the current research work an attempt was made to develop "Melt in mouth pellets" (Meltlets(®)) containing 40% herbal extract of soy isoflavones that served to provide antioxidants activity in menopausal women. The process of extrusion-spheronization was optimized for extruder speed, extruder screen size, spheroniza...

journal_title：Indian journal of pharmaceutical sciences

authors： Deshmukh K,Amin P

更新日期：2013-07-01 00:00:00

abstract：:A series of novel N-Sulphonamidomethyl piperzinyl fluoroquinolones were synthesized and screened antiviral activity. Eight compounds were synthesized through modifying the N(4)-hydrogen of piperazine in fluoroquinolones with formaldehyde and sulphanomides by Mannich reactions. The structures of the synthesized compoun...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Rathore P,Karthikumar S,Velkumar K,Palanisamy P,Vijayalakhsmi S,Witvrouw M

更新日期：2009-07-01 00:00:00

abstract：:The aim of the present study was to monitor adverse drug reactions associated with antihypertensive drugs. The study was conducted in medicine out patient department of 150-bed Majeedia Hospital at Hamdard University Campus in New Delhi. The study was conducted by way of one to one patient interview by a registered ph...

journal_title：Indian journal of pharmaceutical sciences

authors： Hussain A,Aqil M,Alam MS,Khan MR,Kapur P,Pillai KK

更新日期：2009-05-01 00:00:00

abstract：:A reverse phase high performance liquid chromatographic method was developed for the simultaneous estimation of atorvastatin calcium and fenofibrate in tablet formulation. The separation was achieved by Luna C18 column and methanol:acetate buffer pH 3.7 (82:18 v/v) as mobile phase, at a flow rate of 1.5 ml/min. Detect...

journal_title：Indian journal of pharmaceutical sciences

authors： Jain N,Raghuwanshi R,Jain D

更新日期：2008-03-01 00:00:00

abstract：:The effectiveness of liposome-mediated gene transfer methods hinges, in part, on the nature of the interaction between the DNA cargo and the liposomes. Here we have examined the effect of quaternization of the cytofectin cationic head group on this interaction and the effect of concentration of the biocompatible, prot...

journal_title：Indian journal of pharmaceutical sciences

authors： Daniels A,Noor-Mahomed N,Singh M,Ariatti M

更新日期：2011-07-01 00:00:00

abstract：:Pueraria tuberosa is known for its therapeutic potentials in cardiovascular disorders, but its effect in angiogenesis has not been studied so far. In this study, a computational approach has been applied to elucidate the role of the phytochemicals in inhibition of angiogenesis through modulation of vascular endothelia...

journal_title：Indian journal of pharmaceutical sciences

authors： Asthana S,Agarwal T,Singothu S,Samal A,Banerjee I,Pal K,Pramanik K,Ray SS

更新日期：2015-07-01 00:00:00

abstract：:Asymmetric membrane capsules are a type of osmotic drug delivery systems. They are nondisintegrating capsules, which utilize osmotic pressure to drive the drug outwards for controlled delivery. Preceded by systems such as elementary osmotic pump, controlled porosity osmotic pump, single composition osmotic tablet this...

journal_title：Indian journal of pharmaceutical sciences

authors： Sahoo PK,Makar H

更新日期：2013-03-01 00:00:00

abstract：:Several 4-arylidene-2-phenyl-1-(2,4,5-trichlorophenyl)-1H-imidazol-5(4H)-ones (4a-q), N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-4-chlorobenzamides (5a-o) and N-(4-benzylidene-5-oxo-2-phenyl-4,5-dihydroimidazol-1-yl)-2,4-dichlorobenzamides (6a-m) were prepared. All newly synthesized compounds have been ...

journal_title：Indian journal of pharmaceutical sciences

authors： Desai NC,Bhavsar AM,Baldaniya BB

更新日期：2009-01-01 00:00:00

abstract：:A simple, accurate and sensitive spectroscopic method has been proposed for the assay of ciprofloxacin in tablet by least square treatment of fourier transform infrared spectrometric data obtained at the wavenumber corresponding to the carbonyl group centered at 1707 cm(-1). The method involves the extraction of the a...

journal_title：Indian journal of pharmaceutical sciences

authors： Pandey S,Pandey P,Tiwari G,Tiwari R,Rai AK

更新日期：2012-01-01 00:00:00

abstract：:WHO reports estimate poisoning as one of the most common causes of increased morbidity and mortality rate world-wide. Various agents such as pesticides, drugs have been used for intentional and accidental poisoning in different countries. In the Indian scenario, pesticides are the most commonly used poisoning agents. ...

journal_title：Indian journal of pharmaceutical sciences

authors： Jesslin J,Adepu R,Churi S

更新日期：2010-09-01 00:00:00

abstract：:Duloxetine hydrochloride is a potent dual reuptake inhibitor of serotonin and norepinephrine used to treat major depressive disorders. The present work describes a simple, precise and accurate HPTLC method for its estimation as bulk and in tablet dosage form. The chromatographic separation was carried out on precoated...

journal_title：Indian journal of pharmaceutical sciences

authors： Dhaneshwar SS,Deshpande P,Patil M,Vadnerkar G,Dhaneshwar SR

更新日期：2008-03-01 00:00:00

abstract：:A high-performance liquid chromatographic method for the estimation of berberine in the stem of Tinospora cordifolia (Willd.) Miers. ex Hook.f. and Thoms. and Tinospora sinensis (Lour.) Merrill is described. The dried stems of T. cordifolia and T. sinensis were defatted with petroleum ether (60-80 degrees ). The marc ...

journal_title：Indian journal of pharmaceutical sciences

authors： Srinivasan GV,Unnikrishnan KP,Rema Shree AB,Balachandran I

更新日期：2008-01-01 00:00:00

abstract：:The results of our previous investigations on extracts of selected marine algae showed that Caulerpa peltata and Padina gymnospora had more promising antiproliferative and antioxidant activities than Gelidiella acerosa and Sargassum wightii. Based on these results, the more active chloroform extract of C. peltata and ...

journal_title：Indian journal of pharmaceutical sciences

authors： Murugan K,Iyer VV

更新日期：2014-11-01 00:00:00

abstract：:Present study reports the development and validation of a simultaneous estimation of metformin and gliclazide in human plasma using supercritical fluid chromatography followed by tandem mass spectrometry. Acetonitrile:water (80:20) mixture was used as a mobile phase along with liquid CO(2) in supercritical fluid chrom...

journal_title：Indian journal of pharmaceutical sciences

authors： Agrawal YK,Gogoi PJ,Manna K,Bhatt HG,Jain VK

更新日期：2010-01-01 00:00:00

abstract：:Mitochondrial sodium calcium exchange inhibitors are novel agents in the treatment of type-II diabetes due to their glucose dependent efficacy. While the compounds of this class are expected to correct hyperglycemia, they do not lower basal blood glucose level, thus avoiding the serious consequences of hypoglycemia. T...

journal_title：Indian journal of pharmaceutical sciences

authors： Dasoondi AS,Singh V,Voleti SR,Tiwari M

更新日期：2008-03-01 00:00:00

abstract：:In the present study, the effect of essential oil of the root of Angelica archangelica Linn. was evaluated against electrically and chemically induced seizures. The seizures were induced in mice by maximal electroshock and pentylenetetrazol. The effect of essential oil of the root of Angelica archangelica on seizures ...

journal_title：Indian journal of pharmaceutical sciences

authors： Pathak S,Wanjari MM,Jain SK,Tripathi M

更新日期：2010-05-01 00:00:00

abstract：:Preparation and in vitro/in vivo evaluation of mifepristone intravaginal ring formulations were investigated. In the present study, it is reported that a mifepristone intravaginal ring of reservoir design comprising of a mifepristone silicone elastomer core enclosed in a silicone layer. During the preparation of intra...

journal_title：Indian journal of pharmaceutical sciences

authors： Duan X,Ning M

更新日期：2015-05-01 00:00:00

abstract：:In the present investigation chitosan has been chemically modified by treating with two different aldehydes like acetaldehyde and propionaldehyde to form Schiff's bases. Schiff's bases of chitosan with acetaldehyde and propionaldehyde were named as polymer A and polymer B, respectively. Fourier Transform Infra Red (FT...

journal_title：Indian journal of pharmaceutical sciences

authors： Wahid A,Sridhar BK,Shivakumar S

更新日期：2008-07-01 00:00:00

abstract：:A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of esomeprazole and domperidone. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths, 301 nm and 284 nm, lambda max of esomeprazole and domperidone respecti...

journal_title：Indian journal of pharmaceutical sciences

authors： Prabu SL,Shirwaikar A,Shirwaikar A,Kumar CD,Joseph A,Kumar R

更新日期：2008-01-01 00:00:00

abstract：:The present study depicts the development of a validated RP-HPLC method for the determination of the pamabrom in presence of degradation products or other pharmaceutical excipients. Stress study was performed on pamabrom and it was found that it degrade sufficiently in acidic, alkali and oxidative condition but less d...

journal_title：Indian journal of pharmaceutical sciences

authors： Shah U,Kavad M,Raval M

更新日期：2014-05-01 00:00:00

abstract：:A gradient reversed phase HPLC method was developed and validated for the analysis of related substances in zonisamide (1,2-benzisoxazole-3-methanesulfonamide), using a Waters Symmetry C8 (150*3.9 mm) column with a flow rate of 1.0 ml/min and detection at 280 nm. The mobile phase component A consisted of a mixture of ...

journal_title：Indian journal of pharmaceutical sciences

authors： Vijayakumar EK,Dhore DM,Kumar M

更新日期：2009-09-01 00:00:00

abstract：:The present study evaluated the in vitro antioxidant potential of different parts of Oroxylum indicum. 2,2-diphelyl 1-picrylhydrazyl (DPPH), nitric oxide, superoxide anion and hydroxyl radical scavenging potential and reductive ability assay of methanol extract of different parts i.e. root, root bark, stem, stem bark,...

journal_title：Indian journal of pharmaceutical sciences

authors： Mishra SL,Sinhamahapatra PK,Nayak A,Das R,Sannigrahi S

更新日期：2010-03-01 00:00:00

abstract：:A simple, rapid, reliable, robust and optimized reversed phase high performance liquid chromatographic method for simultaneous estimation of doxycycline hyclate and curcumin was successfully developed and validated as per International Conference on Harmonization guidelines. The objective was achieved in terms of well...

journal_title：Indian journal of pharmaceutical sciences

authors： Dhal C,Ahmad FJ,Chauhan A,Jyothi M,Singh RM,Saini PK,Mathur SC,Singh GN

更新日期：2015-11-01 00:00:00

abstract：:Pyrazinamide, a highly specific agent against Mycobacterium tuberculosis is used as first-line drug to treat tuberculosis. The current work aims to formulate polymeric nanoparticles based drug delivery system to sustain the release profile and reduce the dosing frequency of pyrazinamide. Further aim was to target the ...

journal_title：Indian journal of pharmaceutical sciences

authors： Varma JN,Kumar TS,Prasanthi B,Ratna JV

更新日期：2015-05-01 00:00:00

abstract：:Floating matrix tablets of domperidone were developed to prolong gastric residence time and thereby increased drug bioavailability. Domperidone was chosen as a model drug because it is poorly absorbed from the lower gastrointestinal tract. The tablets were prepared by wet granulation technique, using polymers such as ...

journal_title：Indian journal of pharmaceutical sciences

authors： Prajapati ST,Patel LD,Patel DM

更新日期：2009-01-01 00:00:00

abstract：:A simple HPLC method was developed and validated for the quantification of zanamivir in permeability studies using Caco-2 cell culture model. Chromatographic resolution was achieved using 98% (v/v) ultrapure water and 2% (v/v) acetonitrile as mobile phase with flow rate of 0.5 ml/min on a BDS Hypersil Cyano column (le...

journal_title：Indian journal of pharmaceutical sciences

authors： Boonyapiwat B,Sarisuta N,Ma Y,Steventon GB

更新日期：2011-09-01 00:00:00