Chromium improves protein deposition through regulating the mRNA levels of IGF-1, IGF-1R, and Ub in rat skeletal muscle cells.

Abstract:

:The aim of this study was to evaluate the impact of three different chromium forms--chromic chloride (CrCl3), chromium picolinate (CrPic), and a newly synthesized complex of chromium chelated with small peptides (CrSP)--on protein metabolism in vitro. In cultured skeletal muscle cells, CrSP was able to increase the basal and insulin-stimulated levels of protein deposition in skeletal muscles cells. CrCl3 and CrPic augmented insulin-stimulated protein synthesis. At the molecular level, insulin significantly increased the mRNA levels of insulin-like growth factor 1 and insulin-like growth factor 1 receptor. These impacts could be enhanced by the addition of chromium, especially CrSP. The mRNA levels of ubiquitin were significantly reduced when cells were cultured with chromium or/and insulin. Assuming that the mRNA level increase or decrease results in increased or decreased levels of these proteins, chromium would improve protein anabolism and reduce protein catabolism and then prove protein deposition in rat skeletal muscle cells.

journal_name

Biol Trace Elem Res

authors

Peng Z,Qiao W,Wang Z,Dai Q,He J,Guo C,Xu J,Zhou A

doi

10.1007/s12011-009-8579-3

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

226-34

issue

2

eissn

0163-4984

issn

1559-0720

journal_volume

137

pub_type

杂志文章
  • Determination of arsenic in scalp hair of children and its correlation with drinking water in exposed areas of Sindh Pakistan.

    abstract::This study was focused on the analysis of arsenic (As) levels in scalp hair of children (age, <10 years) collected from two towns of Khairpur, Pakistan, to evaluate the effects of As-contaminated groundwater. For comparative purposes, scalp hair samples of children were also collected from that area having low levels ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8866-z

    authors: Kazi TG,Baig JA,Shah AQ,Arain MB,Jamali MK,Kandhro GA,Afridi HI,Kolachi NF,Khan S,Wadhwa SK,Shah F

    更新日期:2011-10-01 00:00:00

  • Vanadium and tungsten derivatives as antidiabetic agents: a review of their toxic effects.

    abstract::Tungstate is an oxyanion that has biological similarities to vanadate. In recent years, a number of studies have shown the antidiabetic effects of oral tungstate in animal models of diabetes. However, because of the tissue accumulation and potential toxicity derived from chronic administration of vanadium and tungsten...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1385/BTER:88:2:097

    authors: Domingo JL

    更新日期:2002-08-01 00:00:00

  • The effects of magnesium deficiency on molybdenum metabolism in rats.

    abstract::Our previous report indicated that magnesium (Mg) deficiency increased molybdenum (Mo) concentration in the rat liver, suggesting the possibility that Mg deficiency affects Mo metabolism. Growing male rats were given a control diet or a Mg-deficient diet for 4 weeks. Urine and feces were collected during the second an...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9541-3

    authors: Kim KH,Funaba M,Yoshida M,Matsui T

    更新日期:2013-01-01 00:00:00

  • Small Molecule Modifiers of In Vitro Manganese Transport Alter Toxicity In Vivo.

    abstract::Manganese (Mn) is essential for several species and daily requirements are commonly met by an adequate diet. Mn overload may cause motor and psychiatric disturbances and may arise from an impaired or not fully developed excretion system, transporter malfunction and/or exposure to excessive levels of Mn. Therefore, dec...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1531-7

    authors: Peres TV,Horning KJ,Bornhorst J,Schwerdtle T,Bowman AB,Aschner M

    更新日期:2019-03-01 00:00:00

  • The effect of selenium and vitamin E on microvascular permeability of rat organs.

    abstract::The effects of dietary sodium selenite and vitamin E on the microvascular permeability of rat organs such as heart, brain, kidney, liver and eye were investigated by using the Evans blue leakage method. Combined deficiency of selenium and vitamin E caused an increase in the permeability of the heart and eye with respe...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783332

    authors: Demirel-Yilmaz E,Dinçer D,Yilmaz G,Turan B

    更新日期:1998-07-01 00:00:00

  • Selenium Prevents Lead-Induced Necroptosis by Restoring Antioxidant Functions and Blocking MAPK/NF-κB Pathway in Chicken Lymphocytes.

    abstract::Recent studies have identified a new existence of a genetically programmed and regulated cell death characterized by necrotic cell death morphology, termed necroptosis. Lead (Pb) is a ubiquitously distributed environmental pollutant that is highly toxic to animals and human beings. However, no detailed report has been...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02094-y

    authors: Zhang J,Hao X,Xu S

    更新日期:2020-12-01 00:00:00

  • Safety Assessment of the Trace Element Impurities Ni and Cr in Pharmaceutical Herbal Products for Teething from Polish Pharmacies.

    abstract::Control of elemental impurities (EIs) in pharmaceutical herbal products is currently important but not a very popular topic in modern toxicological analysis. The occurrence and concentration of EIs in the pharmaceutical herbal products should be controlled and meet the standards of directive International Conference o...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-1643-8

    authors: Jurowski K,Krośniak M,Fołta M,Tatar B,Cole M,Piekoszewski W

    更新日期:2019-10-01 00:00:00

  • Altered copper level and renal dysfunction in Nigerian women using skin-whitening agents.

    abstract::The purpose of the study was to determine the concentration of trace elements in serum samples of women who are chronic users of skin-whitening agents as well as the hepatic and renal effects of these agents on these women. The study was conducted among 23 skin-whitening users while 25 women served as the controls. Th...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-8962-8

    authors: Iyanda AA,Anetor J,Adeniyi FA

    更新日期:2011-12-01 00:00:00

  • X-ray fluorescence analysis using synchrotron radiation at the photon factory.

    abstract::X-ray fluorescence experiments at the Photon Factory in Japan are described. An energy-dispersive X-ray fluorescence system was combined with various excitation modes, i.e., a continuum and a monochromatic excitation, which consist of a crystal monochromator or a wide band pass monochromator. These excitation modes pr...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02796677

    authors: Gohshi Y,Iida A,Matsushita T

    更新日期:1987-04-01 00:00:00

  • Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons.

    abstract::Selenium exerts many, if not most, of its physiological functions as a selenocysteine moiety in proteins. Selenoproteins are involved in many biochemical processes including regulation of cellular redox state, calcium homeostasis, protein biosynthesis, and degradation. A neurodevelopmental syndrome called progressive ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-9920-z

    authors: Wirth EK,Bharathi BS,Hatfield D,Conrad M,Brielmeier M,Schweizer U

    更新日期:2014-05-01 00:00:00

  • Effects of alpha-tocopherol on serum trace and major elements in rats with bleomycin-induced pulmonary fibrosis.

    abstract::The study was undertaken to investigate the influence of alpha-tocopherol on zinc, copper, iron, calcium, magnesium, and potassium concentrations in serum of rats with bleomycin-induced pulmonary fibrosis. Fourteen Wistar albino rats were randomly divided into two groups of seven animals each. The first group was trea...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:114:1:175

    authors: Dede S,Mert H,Mert N,Yur F,Ertekin A,Deger Y

    更新日期:2006-01-01 00:00:00

  • Trivalent Chromium has no Effect on Delaying Azoxymethane-Induced Colorectal Cancer in FVB/NJ Mice.

    abstract::As Cr(III) compounds have been shown to increase insulin sensitivity and decrease plasma cholesterol and triglycerides in rodent models of diabetes and insulin resistance and as colorectal cancer risk has been associated with insulin resistance and diabetes, the effects of the Cr(III) compound Cr3 ([Cr3O(O2CCH2CH3)6(H...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0346-z

    authors: White PE,Deng G,Kuykendall MK,Tadros AM,Dyroff SL,Honan RE,Robertson PM,Vincent JB,Rasco JF

    更新日期:2015-11-01 00:00:00

  • Effects of formaldehyde inhalation on zinc, copper and iron concentrations in liver and kidney of male rats.

    abstract::In the present study, adult Wistar albino male rats were exposed to formaldehyde at different periods (subacute and subchronic) and concentrations (5.0 and 10.0 ppm) in order to figure out the changes in the concentration of Zn, Cu and Fe. It was observed that the formaldehyde inhalation caused gradual decline of body...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8686-1

    authors: Ozen OA,Kus I,Bakirdere S,Sarsilmaz M,Yaman M

    更新日期:2011-05-01 00:00:00

  • Metallothionein induction in freshly isolated rat hepatocytes.

    abstract::The control of metallothionein (MT) synthesis was investigated in freshly prepared rat hepatocytes in experiments of short-term duration. Viability and metabolic function were maintained in incubations of 6-h duration. MT synthesis was measurable in hepatocytes from fed rats at Zn concentrations down to 1 microM. Zn a...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783778

    authors: Coyle P,Philcox JC,Rofe AM

    更新日期:1993-01-01 00:00:00

  • Influence of ashing techniques on the analysis of trace elements in animal tissue : I. Wet ashing.

    abstract::A multitude of methods exists at present for the solubilization of biological tissues for atomic absorption analysis. We have examined several common methods of wet ashing using NBS bovine liver in order to determine which acids, acid combinations, or bases should be used as digesting agents for accurate and precise m...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02990451

    authors: Clegg MS,Keen CL,Lönnerdal B,Hurley LS

    更新日期:1981-06-01 00:00:00

  • DNA fragmentation, caspase 3 and prostate-specific antigen genes expression induced by arsenic, cadmium, and chromium on nontumorigenic human prostate cells.

    abstract::Prostate cancer is one of the most common cancers and the second cause of cancer-related deaths among men. Metals are recognized as chemical carcinogens where chronic exposures to such metals are implicated in the development of cancer, including prostate cancer. This in vitro study demonstrates the relative death sen...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0100-y

    authors: El-Atta HM,El-Bakary AA,Attia AM,Lotfy A,Khater SS,Elsamanoudy AZ,Abdalla HA

    更新日期:2014-12-01 00:00:00

  • Comparative assessment of selected metals in the scalp hair and nails of lung cancer patients and controls.

    abstract::Lung cancer is seriously threatening human health and exposure to trace metals is the most important aetiology for lung cancer. Selected essential/toxic metals (Ca, Mg, Na, K, Fe, Zn, Cu, Sr, Li, Co, Mn, Ni, Cr, Cd and Pb) are measured in the scalp hair and nails of lung cancer patients and controls by atomic absorpti...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-9942-6

    authors: Qayyum MA,Shah MH

    更新日期:2014-06-01 00:00:00

  • The effects of dietary supplementation with chromium picolinate throughout gestation on productive performance, Cr concentration, serum parameters, and colostrum composition in sows.

    abstract::The objective of this study was to determine the effects of supplemental chromium as chromium picolinate (CrPic) on productive performance, chromium (Cr) concentration, serum parameters, and colostrum composition in sows. Thirty Yorkshire sows were bred with semen from a pool of Landrace boars. The sows were equally g...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9699-3

    authors: Wang L,Shi Z,Jia Z,Su B,Shi B,Shan A

    更新日期:2013-07-01 00:00:00

  • Effect of High Static Magnetic Field (2 T-12 T) Exposure on the Mineral Element Content in Mice.

    abstract::Relative stability of mineral elements in tissues is necessary for health. High static magnetic fields (HiSMFs) have been widely used in biomedical research and industry. However, the bioeffect of HiSMFs on animals is still unclear. In this study, we investigated the effects of HiSMF exposure on the levels of Mg, Fe, ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02469-1

    authors: Wang S,Huyan T,Zhou L,Xue Y,Guo W,Yin D,Shang P

    更新日期:2021-01-07 00:00:00

  • Fluoride and Biological Calcification I: Effect of Fluoride on Collagen-Induced In Vitro Mineralization and Demineralization Reactions.

    abstract::An in vitro system employing collagen isolated from the sheep tendons to induce mineralization and demineralization reactions was used not only to study the effect of various concentrations of fluoride on the collagen-induced mineralization and demineralization reactions but also to compare their action with the inhib...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02340-3

    authors: Kakkar M,Kapoor V,Singla SK,Jethi RK

    更新日期:2020-08-27 00:00:00

  • Oral treatment of pressure ulcers with polaprezinc (zinc L-carnosine complex): 8-week open-label trial.

    abstract::Polaprezinc (zinc L-carnosine complex) is a tablet commonly prescribed for gastric ulcers in Japan. Recently, we reported the effects of polaprezinc on pressure ulcer healing at 4-week follow-up. We aimed to further evaluate the efficacy and safety of polaprezinc in 8-week treatment for chronic pressure ulcers. Patien...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12011-014-9943-5

    authors: Sakae K,Yanagisawa H

    更新日期:2014-06-01 00:00:00

  • Developmental effects of boric acid in rats related to maternal blood boron concentrations.

    abstract::Timed-mated Sprague-Dawley rats (60/group) were exposed to boric acid (BA) from gestational days (gd) 0 to 20. BA added to the diet (0, 0.025, 0.050, 0.075, 0.1, or 0.2%) yielded boron (B) intakes of <0.35 (control), 3, 6, 10, 13, or 25 mg B/kg body wt/d. Approximately one-half of the dams/group were terminated on gd ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783148

    authors: Price CJ,Strong PL,Murray FJ,Goldberg MM

    更新日期:1998-01-01 00:00:00

  • Chromium improves glucose uptake and metabolism through upregulating the mRNA levels of IR, GLUT4, GS, and UCP3 in skeletal muscle cells.

    abstract::The aim of this study was to evaluate the impact of three different chromium forms as chromic chloride (CrCl), chromium picolinate (CrPic), and a newly synthesized complex of chromium chelated with small peptides (CrSP) on glucose uptake and metabolism in vitro. In cultured skeletal muscle cells, chromium augmented in...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-009-8357-2

    authors: Qiao W,Peng Z,Wang Z,Wei J,Zhou A

    更新日期:2009-11-01 00:00:00

  • Ethanol Exacerbates Manganese-Induced Neurobehavioral Deficits, Striatal Oxidative Stress, and Apoptosis Via Regulation of p53, Caspase-3, and Bax/Bcl-2 Ratio-Dependent Pathway.

    abstract::This study investigated the effects of ethanol (EtOH) on manganese (Mn)-induced striatal toxicity in rat by evaluating the neurobehavioral changes, biochemical and molecular events in rats exposed to Mn alone at 30 mg/kg, or their combination with EtOH at 1.25- and 5-g/kg body weight for 35 consecutive days. Locomotiv...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1587-4

    authors: Nkpaa KW,Awogbindin IO,Amadi BA,Abolaji AO,Adedara IA,Wegwu MO,Farombi EO

    更新日期:2019-09-01 00:00:00

  • Ensemble modeling coupled with six element concentrations in human blood for cancer diagnosis.

    abstract::Six important metal contents (i.e., zinc, barium, magnesium, calcium, copper, and selenium) in blood samples coupled with an ensemble classification algorithm have been used for the classification of normal people and cancer patients. A dataset containing 42 healthy samples and 32 cancer samples was used for experimen...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8864-1

    authors: Chen H,Tan C,Wu T

    更新日期:2011-10-01 00:00:00

  • Study of chemical species of iodine in human liver.

    abstract::The distribution and chemical species of iodine in various subcellular fractions of human liver were studied by using epithermal neutron activation analysis combined with chemical and biochemical separation techniques, such as gradient centrifugation and gel chromatography. It was found that the total iodine content o...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783916

    authors: Hou X,Chen C,Ding W,Chai C

    更新日期:1999-07-01 00:00:00

  • A comparative study in Alzheimer's and normal brains of trace element distribution using PIXE and INA analyses and glucose metabolism by positron emission tomography.

    abstract::The onset of Alzheimer's disease has been shown to affect trace element concentrations in the brain when compared to "normal" subjects in ex vivo samples. The techniques used to determine trace element concentrations were proton-induced X-ray emission and instrumental neutron activation analysis. With these methods, s...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02784242

    authors: Cutts DA,Maguire RP,Stedman JD,Leenders KL,Spyrou NM

    更新日期:1999-01-01 00:00:00

  • Selenium deficiency is associated with endoplasmic reticulum stress in a rat model of cardiac malfunction.

    abstract::The relationship between selenium (Se) deficiency-induced cardiac malfunction and endoplasmic reticulum (ER) stress is poorly understood. In the present study, 18 weaning Sprague Dawley rats were randomly fed with three different Se diets, and myocardial glutathione peroxidase (GPx) activity was measured by an enzyme ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9834-1

    authors: Wang SQ,Niu XL,Liu ZW,Zhu YH,Gao DF

    更新日期:2013-12-01 00:00:00

  • Se Deficiency Induced Inflammation Resulting to a Diminished Contraction of the Small Intestinal Smooth Muscle in Mice.

    abstract::Selenium (Se) is an essential trace element for both humans and animals. Se deficiency leads to myocardial injury, reproductive disorder, increased exudation, inflammatory injury, and other diseases. The present study analyzed the relationships of Se deficiency, inflammation, and smooth muscle contraction in the small...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02245-1

    authors: Wang YS,Teng GQ,Zhou H

    更新日期:2020-06-15 00:00:00

  • The Fructoborates: Part of a Family of Naturally Occurring Sugar-Borate Complexes-Biochemistry, Physiology, and Impact on Human Health: a Review.

    abstract::Sugar-borates (SBs) are mono- or di-sugar-borate esters (SBEs) comprised of one or two monosaccharide molecules linked to a boron (B) atom. SBEs occur naturally in commonly consumed herbs, vegetables, fruits, seeds, and nuts and, other than greatly varying levels of B found in local drinking water, are the primary nat...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1007/s12011-018-1550-4

    authors: Hunter JM,Nemzer BV,Rangavajla N,Biţă A,Rogoveanu OC,Neamţu J,Scorei IR,Bejenaru LE,Rău G,Bejenaru C,Mogoşanu GD

    更新日期:2019-03-01 00:00:00