Abstract：
:The purpose of the study was to determine the concentration of trace elements in serum samples of women who are chronic users of skin-whitening agents as well as the hepatic and renal effects of these agents on these women. The study was conducted among 23 skin-whitening users while 25 women served as the controls. The serum concentrations of Zn, Mn, and Mg were not significantly changed in these women compared with controls (p > 0.05), but Cu was significantly increased in skin-whitening agent users compared with controls (p < 0.05). Serum urea and creatinine were significantly increased compared with the controls (p < 0.05). Moreover, ALT, AST, albumin, total protein, and bilirubin were not significantly changed (p > 0.05). The significant increase in the levels of renal indices shows that these agents might be nephrotoxic after prolonged usage while increase in copper level with accompanying renal dysfunction may be an indication that copper mediates in oxidative-induced renal dysfunction. However, further study is needed to identify the cause and source of high serum copper as many of the herbal extracts may be rich sources of copper. Moreover, a large population study may be necessary to examine the exact correlation between copper and renal indices.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Iyanda AA,Anetor J,Adeniyi FAdoi
10.1007/s12011-011-8962-8subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1264-70issue
3eissn
0163-4984issn
1559-0720journal_volume
143pub_type
杂志文章abstract：:The objective was to determine if a mammary cell line shows glucocorticoid stimulation of Zn uptake, and to determine whether polyamines mediate this stimulation. 65Zn uptake by COMMA-1D mouse mammary epithelial cells over a 24-h period increased significantly in cells administered 10(-7) or 10(-6) M hydrocortisone. I...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783193
更新日期：1993-11-01 00:00:00
abstract：:Two organoselenium compounds: xylitol selenious ester (xylitol-Se) and sucrose selenious ester (sucrose-Se) were synthesized, and their molecular structures were characterized in this study. In MTT assay, xylitol-Se and sucrose-Se showed cytostatic effects on human hepatocellular carcinoma cells SMMC-7221 in a dose-de...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-013-9715-7
更新日期：2013-08-01 00:00:00
abstract：:An external-sample liquid scintillation (LS) counting for the gamma emitter 75Se has been developed. An expressly designed well-type LS vial and a 2,5-diphenyoxazole-1,4-bis(5-phenyl-2-oxazoyl)-benzene-xylene solution containing 35% tertrabutylzinn allow 75Se to be counted in a standard LS counter with counting effici...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:77:3:287
更新日期：2000-12-01 00:00:00
abstract：:In the present world, X-rays have been regarded as one of the most efficient tools in medicine, industry and research. On the contrary, extensive human exposure to these rays is responsible for causing detrimental effects on physiological system. The aim of the present study was to investigate the role of zinc (Zn), i...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-0976-4
更新日期：2017-10-01 00:00:00
abstract：:Calcium, magnesium, and zinc balances were determined in eleven young adult college females (mean age, 24.9±2.35) during a 39-d metabolic study when the subjects were fed an adequate calorie and protein diet based on habitually consumed foods. Analysis showed that the dietary contribution of calcium, magnesium, and zi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917454
更新日期：1985-11-01 00:00:00
abstract：:The interaction of VO2+ with the muchopolysaccharide chondroitin sulfate A (CSA) has been investigated by electron absorption spectroscopy and infrared measurements in aqueous solutions at different pH-values and ligand to metal ratios up to 6:1. The generation of a VO(CSA)2 species could be demonstrated. Coordination...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02990487
更新日期：1994-07-01 00:00:00
abstract：:Attempts were made to promote germination of natural aged rice seeds by treating them with lanthanum nitrate. In tests to measure the germination rate, germination index, and vigor index of natural aged rice seeds were found to be significantly increased by lanthanum. It is treating aged rice seed with lanthanum nitra...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/bter:75:1-3:205
更新日期：2000-07-01 00:00:00
abstract：:The effects of zinc on growing rats were characterized using the dietary zinc-deficient (ZD) and Zinc-overdose (ZO) models. Zinc deficiency had negative effects on the host final body weight and liver zinc content, whereas zinc overdose had positive effects. In order to identify the molecular changes in the liver resp...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02686028
更新日期：2007-02-01 00:00:00
abstract：:To examine longitudinal and gestational effects of mineral content in human milk, we analyzed human milk from lactating mothers of premature (PRT, n = 24, < 2000 g birth weight, < 37 wk gestation) and full-term (FT, n = 19, > 2500 g, 39-41 wk gestation), living in Newfoundland, Canada. Samples were collected once a we...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784423
更新日期：1999-03-01 00:00:00
abstract：:Placental type 3 iodothyronine deiodinase (D3) potentially protects the fetus from the elevated maternal thyroid hormones. Na(+)/I(-) symporter (NIS) is a plasma membrane glycoprotein, which mediates active iodide uptake. Our objectives were to establish the distribution of NIS and D3 gene expressions in the placenta ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-013-9748-y
更新日期：2013-09-01 00:00:00
abstract：:The aim of this study was to investigate the protective effects of erdosteine and vitamins C and E (VCE) on the lungs after performing hind limb ischemia-reperfusion (I/R) by assessing oxidative stress, plasma copper (Cu), and zinc (Zn) analysis. The animals were divided randomly into four groups as nine rats each as ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-0010-3
更新日期：2007-07-01 00:00:00
abstract：:Selenium (Se) deficiency in the experimental models, Coturnix coturnix japonica and Corcyra cephalonica, resulted in impaired mitochondrial substrate oxidations and lowered thiol levels. Studies with respiratory inhibitors confirmed reduced mitochondrial electron transport enzyme activities, especially at cytochrome c...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784077
更新日期：1996-03-01 00:00:00
abstract：:Copper is an essential trace element with various biological functions. Excess copper, however, is extremely toxic, leading to many pathological conditions that are consistent with oxidative damage to membranes and molecules. Exposure to high levels of copper results in various changes in the tissues. In liver, hypert...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:96:1-3:209
更新日期：2003-01-01 00:00:00
abstract：:Lead is a biohazardous metal that is commonly involved in human illness including renal injury. Although it is a non-redox reactive metal, lead-induced renal injury is largely based on oxidative stress. The current work aimed at exploring the possible protective effect of γ-glutamyl cysteine (γGC) against lead-induced...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0624-4
更新日期：2016-09-01 00:00:00
abstract：:We investigated the rooting rate, the number of roots, and the state of growth of loquat (Eriobotrya japonica Lindi) plantlet in medium where La(NO3)3 (0.5-100.0 micromol/L) was added 20 d after transplanting. The activity of peroxidase, nitrate reductase, and the fresh weight of roots were determined 44 d after trans...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/bter:89:3:277
更新日期：2002-12-01 00:00:00
abstract：:The present study was conducted to assess the influence of dietary zinc nanoparticles (size 50 nm) on the growth, biochemical constituents, enzymatic antioxidant levels and the nonspecific immune response of the freshwater prawn, Macrobrachium rosenbergii post larvae (PL). The concentrations of dietary supplement zinc...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0026-4
更新日期：2014-07-01 00:00:00
abstract：CONTEXT:Complementary alternative medicine therapies based on the use of cesium chloride preparations for the treatment of cancer and radiation poisoning, have generated therapeutic interest; but oral or intravenous administration of cesium chloride (CsCl) to cancer patients as an alternative mode of cancer therapy hav...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:94:2:97
更新日期：2003-08-01 00:00:00
abstract：:Various studies indicate the role of manganese (Mn) in the virulence of pathogens. Salmonella is an intracellular pathogen which is able to multiply within the macrophages. The present study was therefore, designed to assess the effect of Mn supplementation on Salmonella-macrophage interactions particularly in referen...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8406-x
更新日期：2010-01-01 00:00:00
abstract：:To elucidate compositional changes of the mitral valve with aging, the authors investigated the relationships among element contents in the mitral valves. The subjects consisted of 10 men and 15 women, ranging in age from 65 to 102 yr. After the ordinary dissection, mitral valves, lower parts of the interventricular s...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:88:3:203
更新日期：2002-09-01 00:00:00
abstract：:The developmental alterations in metallothionein (MT) proteins and zinc (Zn) were investigated in brains of two transgenic strains of mice. MT protein was measured by a cadmium binding assay and Zn by atomic absorption spectrophotometry. MT proteins were expressed at birth (day 1) both in MT-I overexpressing transgeni...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784039
更新日期：1998-01-01 00:00:00
abstract：:The influence of hair color on the trace elemental status in horse's hair has been studied. A current analytical technique such as particle-induced X-ray emission (PIXE) used in this study has provided reliable, rapid, easy, and relatively inexpensive diagnostic methods. Twenty-eight elements (Al, Br, Ca, Cl, Co, Cu, ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:103:2:169
更新日期：2005-02-01 00:00:00
abstract：:The k0 standardization method was adapted for NAA with stable low-flux reactors where flux monitors are not needed. The modified k0 method offers the convenience of the use of libraries of sensitivity constants. It was compared to the relative method for 52 elements using a SLOWPOKE reactor and 6 counting geometries. ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784232
更新日期：1999-01-01 00:00:00
abstract：:The aim of this study was to investigate the effects of the Toxoplasma gondii infection on the total content of the essential elements Zn and Mg levels. Plasma zinc and magnesium concentrations were measured in 158 patients whose anti-T gondii IgG antibodies were positive. Scores were obtained for the patients and the...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1385/BTER:92:1:11
更新日期：2003-04-01 00:00:00
abstract：:In brain, excess zinc alters the metabolism of amyloid precursor protein, leading to β-amyloid protein deposition, one of the hallmarks of Alzheimer's disease (AD) pathology. Recently, it has been reported that zinc accelerates in vitro tau fibrillization, another hallmark of AD. In the current study, we examined the ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9411-z
更新日期：2012-11-01 00:00:00
abstract：:Concentrations of toxic elements (lead, cadmium, mercury, and arsenic) were measured in water, sediment, and four commercial fish species (Cyprinus carpio, Hypophthalmichthys molitrix, Silurus glanis, and Esox lucius) and their tissues (muscle, liver, and kidney) from Saničani Lake, Bosnia and Herzegovina. The concent...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01982-2
更新日期：2020-09-01 00:00:00
abstract：:The aim of this study was to assess the effect of sibutramine on mineral status and selected biochemical parameters in obese women. The study was conducted on 24 patients who received 15 mg daily doses of sibutramine for 12 weeks, and on 20 patients who received placebo. At the baseline, after the sixth and twelfth we...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9425-6
更新日期：2012-11-01 00:00:00
abstract：:The Nord-Trøndelag Health Study (The HUNT Study) is a large health survey population study in the county of Trøndelag, Norway. The survey has been repeated four times in about 10-year intervals. In the HUNT3 survey (2006-2008), we collected 28,000 samples for trace element analysis. Blood samples from 758 healthy pers...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02376-5
更新日期：2020-09-08 00:00:00
abstract：:Among the trace elements, zinc is one of the most used elements in biological systems. Zinc is found in the structure of more than 2700 enzymes, including hydrolases, transferases, oxyreductases, ligases, isomerases, and lyases. Not surprisingly, it is present in almost all body cells. Preserving the stability and int...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/s12011-017-1119-7
更新日期：2018-05-01 00:00:00
abstract：:Intraperitoneal administration of zinc chloride (ZnCl2) to Swiss albino mice in vivo induced a significant (p less than or equal to 0.05) increase in the frequencies of chromosomal aberrations of the bone-marrow cells at all concentrations used following acute (7.5, 10, 15 mg/kg body weight) and chronic (2.0, 3.0 mg/k...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02990346
更新日期：1991-08-01 00:00:00
abstract：:Tomato quality and its potential health benefits are directly related to its chemical composition. The characterization of nutritional properties of Solanum germplasm is essential to choose suitable donor parents for breeding programs. In this sense, wild species could be very useful for tomato fruit quality genetic i...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8738-6
更新日期：2011-06-01 00:00:00
