Analyses of injury count data: some do's and don'ts.

Abstract:

:The analysis of injury data requires different considerations from the analysis of other types of outcomes because an individual can experience the outcome many times. When describing injury patterns using numerator-only data (e.g., proportion of upper-extremity injuries vs. lower-extremity injuries), simple comparisons of proportions are inappropriate because 1) individuals are compared with themselves and 2) multiple testing increases the potential for incorrect inference. Bootstrapping (resampling) techniques can be used to determine confidence intervals and whether the frequencies significantly differ across categories. When describing injury rates, the authors suggest plotting the observed injury rate against the number of exposures to obtain a visual representation of the heterogeneity of risk across individuals. Because the distribution of injury rates is often skewed, some research questions may be best addressed by comparing the weighted median injury rates instead of the weighted mean injury rates (which are given by standard formulae). Again, resampling techniques can be used to obtain a null distribution for injury rates in order to determine whether there are subjects who have unexpectedly high injury rates. More advanced analyses are required to account for multiplicity.

journal_name

Am J Epidemiol

authors

Shrier I,Steele RJ,Hanley J,Rich B

doi

10.1093/aje/kwp265

subject

Has Abstract

pub_date

2009-11-15 00:00:00

pages

1307-15

issue

10

eissn

0002-9262

issn

1476-6256

pii

kwp265

journal_volume

170

pub_type

杂志文章
  • An epidemic of gastroenteritis traced to a contaminated public water supply.

    abstract::Between January 1 and March 15, 1974, approximately 1200 cases of acute gastrointestinal illness occurred in Richmond Heights, Florida, a residential community of 6500 in south Dade County. Over one-third of all families in the area had at least one member affected. The findings of 10 culture-proven cases of shigellos...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112238

    authors: Weissman JB,Craun GF,Lawrence DN,Pollard RA,Saslaw MS,Gangarosa EJ

    更新日期:1976-04-01 00:00:00

  • Healthy Aging 5 Years After a Period of Daily Supplementation With Antioxidant Nutrients: A Post Hoc Analysis of the French Randomized Trial SU.VI.MAX.

    abstract::This study's objective was to investigate healthy aging in older French adults 5 years after a period of daily nutritional-dose supplementation with antioxidant nutrients. The study was based on the double-blind, randomized trial, Supplementation with Antioxidant Vitamins and Minerals (SU.VI.MAX) Study (1994-2002) and...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwv105

    authors: Assmann KE,Andreeva VA,Jeandel C,Hercberg S,Galan P,Kesse-Guyot E

    更新日期:2015-10-15 00:00:00

  • Birth weight and mortality: causality or confounding?

    abstract::The association between birth weight and mortality is among the strongest seen in epidemiology. While preterm delivery causes both small babies and high mortality, it does not explain this association. Fetal growth restriction has also been proposed, although its features are unclear because it lacks a definition inde...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj237

    authors: Basso O,Wilcox AJ,Weinberg CR

    更新日期:2006-08-15 00:00:00

  • Risk factors for mortality from all causes and from coronary heart disease among persons with diabetes. Findings from the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study.

    abstract::Coronary heart disease is the leading cause of mortality among persons with diabetes mellitus, but the factors that account for this high coronary heart disease mortality remain unclear. In the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study, conducted from 1982 to 1984, 92 deaths from...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115834

    authors: Ford ES,DeStefano F

    更新日期:1991-06-15 00:00:00

  • Lung cancer mortality and polynuclear aromatic hydrocarbons: a case-cohort study of aluminum production workers in Arvida, Quebec, Canada.

    abstract::The authors report the results of a case-cohort study of 338 lung cancer deaths in 1950-1988 and a random sample (sub-cohort) of 1,138 from among 16,297 men who had worked at least one year between 1950 and 1979 in manual jobs at a large aluminum production plant. In the past, certain workers were exposed to substanti...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116992

    authors: Armstrong B,Tremblay C,Baris D,Thériault G

    更新日期:1994-02-01 00:00:00

  • The relationship between hormonal pregnancy tests and congenital anomalies: a prospective study.

    abstract::In a prospective study of some 20,000 pregnancies in the Child Health and Development Studies in the San Francisco East Bay area, 226 gravidas were tested for pregnancy with estrogen/progestogen preparations. The two control groups were women who were tested for pregnancy by either a serum or urine test. There were no...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113133

    authors: Torfs CP,Milkovich L,van den Berg BJ

    更新日期:1981-05-01 00:00:00

  • Socioeconomic status and asthma prevalence in young adults: the European Community Respiratory Health Survey.

    abstract::The authors assessed the association between asthma prevalence and socioeconomic status at both the individual and center levels simultaneously.by using data from 32 centers in 15 countries. Included were 10,971 subjects aged 20-44 years selected from the general population and interviewed in 1991-1992. Socioeconomic ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/aje/kwh186

    authors: Basagaña X,Sunyer J,Kogevinas M,Zock JP,Duran-Tauleria E,Jarvis D,Burney P,Anto JM,European Community Respiratory Health Survey.

    更新日期:2004-07-15 00:00:00

  • Cancer Incidence and Mortality in the Oldest Old: a Nationwide Study in Finland.

    abstract::The world's population is aging rapidly. This study reports the burden of cancer in the oldest old (≥85 years) in Finland in 1953-2017 and estimates age-specific cancer rates in the old population (65-99 years) in 1988-2017. The Finnish Cancer Registry provided data on all cancer diagnoses, cancer deaths and other dea...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwaa236

    authors: Tanskanen T,Seppä KJM,Virtanen A,Malila NK,Pitkäniemi JM

    更新日期:2020-10-22 00:00:00

  • Familial aggregation of fetal growth restriction in a French cohort of 7,822 term births between 1971 and 1985.

    abstract::An association between fetal growth restriction and increased rates of metabolic and cardiovascular diseases in adulthood has been reported. This study evaluated familial aggregation of fetal growth restriction in term births. The population consisted of 3,505 sibships comprised of 7,822 full-term singleton infants bo...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwf002

    authors: La Batide-Alanore A,Trégouët DA,Jaquet D,Bouyer J,Tiret L

    更新日期:2002-07-15 00:00:00

  • Invited commentary: a sunbed epidemic?

    abstract::The Icelandic study of melanoma trends by Héry et al. in this issue of the Journal (Am J Epidemiol. 2010;172(7):762-767) is a fascinating analysis of an ecologic association. The authors noted a sharp increase in melanoma incidence that appeared to lag a few years behind the increased prevalence of sunbeds in Iceland....

    journal_title:American journal of epidemiology

    pub_type: 评论,杂志文章,评审

    doi:10.1093/aje/kwq232

    authors: Berwick M

    更新日期:2010-10-01 00:00:00

  • Analgesic drug use and risk of epithelial ovarian cancer.

    abstract::Analgesic use may reduce ovarian cancer risk, possibly through antiinflammatory or antigonadotropic effects. The authors conducted a population-based, case-control study in Washington State that included 812 women aged 35-74 years who were diagnosed with epithelial ovarian cancer between 2002 and 2005 and 1,313 contro...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwn082

    authors: Hannibal CG,Rossing MA,Wicklund KG,Cushing-Haugen KL

    更新日期:2008-06-15 00:00:00

  • Tobacco, alcohol, and colorectal tumors: a multistep process.

    abstract::A case-control study in the Côte d'Or area of France used the multistep concept of colorectal carcinogenesis to compare lifetime tobacco consumption and present alcohol consumption in patients with small adenomas (less than 1 cm, n = 154) or large adenomas (n = 208) and in polyp-free controls (n = 427). Cancer patient...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Boutron MC,Faivre J,Dop MC,Quipourt V,Senesse P

    更新日期:1995-06-01 00:00:00

  • Risk factors for neonatal seizures: a population-based study, Harris County, Texas, 1992-1994.

    abstract::Risk factors for neonatal seizures were evaluated in 116,048 infants born between 1992 and 1994 to residents of Harris County, Texas; 207 of these infants were diagnosed with clinical neonatal seizures. Information was obtained from the infant's birth certificate to assess the relation between seizures and birth weigh...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/154.1.14

    authors: Saliba RM,Annegers FJ,Waller DK,Tyson JE,Mizrahi EM

    更新日期:2001-07-01 00:00:00

  • Gallstones, cholecystectomy, and risk of digestive system cancers.

    abstract::Gallstones and cholecystectomy may be related to digestive system cancer through inflammation, altered bile flux, and changes in metabolic hormone levels. Although gallstones are recognized causes of gallbladder cancer, associations with other cancers of the digestive system are poorly established. We used the Surveil...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwt322

    authors: Nogueira L,Freedman ND,Engels EA,Warren JL,Castro F,Koshiol J

    更新日期:2014-03-15 00:00:00

  • Coronary heart disease prevalence and its relation to risk factors in American Indians. The Strong Heart Study.

    abstract::Although coronary heart disease (CHD) is currently the leading cause of death among American Indians, information on the prevalence of CHD and its association with known cardiovascular risk factors is limited. The Strong Heart Study was initiated in 1988 to quantify cardiovascular disease and its risk factors among th...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117632

    authors: Howard BV,Lee ET,Cowan LD,Fabsitz RR,Howard WJ,Oopik AJ,Robbins DC,Savage PJ,Yeh JL,Welty TK

    更新日期:1995-08-01 00:00:00

  • "If it isn't ultimately aimed at policy, it's not worth doing": interview of George W. Comstock by Alfredo Morabia.

    abstract::George W. Comstock (1915-2007), MD, MPH, DrPH, was lecturer and then professor of epidemiology at the Johns Hopkins University School of Hygiene and Public Health from 1956 to 2007 and served as editor-in-chief of the American Journal of Epidemiology from 1979 to 1988. This interview of George W. Comstock took place i...

    journal_title:American journal of epidemiology

    pub_type: 传,历史文章,面试

    doi:10.1093/aje/kwt027

    authors: Morabia A

    更新日期:2013-04-01 00:00:00

  • Congenital heart disease: prevalence at livebirth. The Baltimore-Washington Infant Study.

    abstract::The Baltimore-Washington Infant Study is a regional epidemiologic study of congenital heart disease. Among Infants born in the study area in 1981 and 1982, 664 had a diagnosis of congenital heart disease confirmed in the first year of life by echocardiography, cardiac catheterization, cardiac surgery, or autopsy. The ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113979

    authors: Ferencz C,Rubin JD,McCarter RJ,Brenner JI,Neill CA,Perry LW,Hepner SI,Downing JW

    更新日期:1985-01-01 00:00:00

  • Total and Cause-Specific Mortality Risk Associated With Low-Level Exposure to Crystalline Silica: A 44-Year Cohort Study From China.

    abstract::The association between low-level crystalline silica (silica) exposure and mortality risk is not well understood. We investigated a cohort of 44,807 Chinese workers who had worked in metal mines or pottery factories for at least 1 year from January 1, 1960, to December 31, 1974, and were followed through 2003. Low-lev...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwx124

    authors: Liu Y,Zhou Y,Hnizdo E,Shi T,Steenland K,He X,Chen W

    更新日期:2017-08-15 00:00:00

  • Relations among standard epidemiologic measures in a population.

    abstract::Recent developments in population mathematics apply to measurement issues in epidemiology. In particular, they demonstrate explicitly the relations that prevail among incidence, prevalence, case-fatality, mortality, and duration of illness in a population at a moment in time, rather than in a cohort of persons followe...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/126.2.336

    authors: Preston SH

    更新日期:1987-08-01 00:00:00

  • An epidemic of hepatitis A in an institution for young children.

    abstract::A common-source epidemic of hepatitis A occurred in an Athenian institution boarding 38 children (mean age 4.8 years). All children were examined, and blood was drawn from each at the onset of the study and repeatedly during the next three months. Only one child (2.6%) was initially immune to hepatitis A virus as a re...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114530

    authors: Tassopoulos NC,Roumeliotou-Karayannis A,Sakka M,Ticehurst J,Mihalik K,Stephanou T,Purcell RH,Papaevangelou G

    更新日期:1987-02-01 00:00:00

  • Cognitive disorders and occupational exposure to organophosphates: results from the PHYTONER study.

    abstract::The involvement of organophosphate insecticides in cognitive disorders is supported by epidemiologic and biological evidence, but the effects of long-term exposure remain debated. We studied the association between organophosphate exposure and cognitive performance in vine workers from the PHYTONER study cohort in the...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kws346

    authors: Blanc-Lapierre A,Bouvier G,Gruber A,Leffondré K,Lebailly P,Fabrigoule C,Baldi I

    更新日期:2013-05-15 00:00:00

  • Alcohol consumption with age: a cross-sectional and longitudinal study of the Atherosclerosis Risk in Communities (ARIC) study, 1987-1995.

    abstract::Previous cross-sectional and longitudinal studies assessing the association between age and drinking are inconsistent. Evaluating 15,425 Black and White men and women from four communities, this study sought to determine whether there was a consistent relation between age and drinking in cross-sectional and longitudin...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/153.11.1102

    authors: Eigenbrodt ML,Mosley TH Jr,Hutchinson RG,Watson RL,Chambless LE,Szklo M

    更新日期:2001-06-01 00:00:00

  • Strategies for pandemic and seasonal influenza vaccination of schoolchildren in the United States.

    abstract::Vaccinating school-aged children against influenza can reduce age-specific and population-level illness attack rates. Using a stochastic simulation model of influenza transmission, the authors assessed strategies for vaccinating children in the United States, varying the vaccine type, coverage level, and reproductive ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwp237

    authors: Basta NE,Chao DL,Halloran ME,Matrajt L,Longini IM Jr

    更新日期:2009-09-15 00:00:00

  • Exogenous estrogens and endometrial cancer: a case-control study and assessment of potential biases.

    abstract::Eighty-eight cases with newly diagnosed carcinoma of the endometrium and 177 age-matched neighborhood controls were interviewed to test the hypothesis that exogenous estrogens lead to an increased risk of endometrial cancer. Forth-five per cent of the cases and 22% of the controls reported a history of estrogen use wh...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113215

    authors: Spengler RF,Clarke EA,Woolever CA,Newman AM,Osborn RW

    更新日期:1981-10-01 00:00:00

  • Blood Pressure and Arterial Stiffness in Kenyan Adolescents With the Sickle Cell Trait.

    abstract::The potential association between sickle cell trait (SCT) and increased arterial stiffness/blood pressure (BP) has not been evaluated in detail despite its association with stroke, sudden death, and renal disease. We performed 24-hour ambulatory BP monitoring and arterial stiffness measurements in adolescents raised i...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwx232

    authors: Etyang AO,Wandabwa CK,Kapesa S,Muthumbi E,Odipo E,Wamukoya M,Ngomi N,Haregu T,Kyobutungi C,Williams TN,Makale J,Macharia A,Cruickshank JK,Smeeth L,Scott JAG

    更新日期:2018-02-01 00:00:00

  • Prevalence, detection, and control of hypertension in a biethnic community. The San Antonio Heart Study.

    abstract::A survey was carried out on a random sample of 1,288 Mexican Americans and 929 Anglos living in three socially distinct neighborhoods in San Antonio, Texas. Hypertension was defined as diastolic blood pressure greater than or equal to 95 mmHg or currently taking antihypertensive medication. Overall age-adjusted preval...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/121.5.684

    authors: Franco LJ,Stern MP,Rosenthal M,Haffner SM,Hazuda HP,Comeaux PJ

    更新日期:1985-05-01 00:00:00

  • Sex-specific associations of magnetic resonance imaging-derived intra-abdominal and subcutaneous fat areas with conventional anthropometric indices. The Atherosclerosis Risk in Communities Study.

    abstract::Accurate measurement of central fat patterning is difficult to obtain by conventional anthropometry. Direct measurement of intra-abdominal fat area by magnetic resonance imaging, while accurate, is impractical for large-scale observational studies. This report examines the sex-specific associations of conventional ant...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008934

    authors: Schreiner PJ,Terry JG,Evans GW,Hinson WH,Crouse JR 3rd,Heiss G

    更新日期:1996-08-15 00:00:00

  • Ten largest racial and ethnic health disparities in the United States based on Healthy People 2010 Objectives.

    abstract::A consistent framework has been developed for measuring health disparities and making comparisons across indicators with regard to the public health goals of Healthy People 2010. Disparities are measured as the percent difference from the best group rate, with all indicators being expressed in terms of adverse events....

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwm044

    authors: Keppel KG

    更新日期:2007-07-01 00:00:00

  • Diet and cancer mortality in the counties of Sweden.

    abstract::The association between standardized cancer mortality rate ratios from 1969-1978 and dietary practices was examined in an ecologic study of the 24 counties of Sweden by means of several independent data sources. The study supports the hypothesis that a high intake of cereal fiber protects against colorectal cancer (r ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.aje.a114789

    authors: Rosén M,Nyström L,Wall S

    更新日期:1988-01-01 00:00:00

  • A Note on G-Estimation of Causal Risk Ratios.

    abstract::G-estimation is a flexible, semiparametric approach for estimating exposure effects in epidemiologic studies. It has several underappreciated advantages over other propensity score-based methods popular in epidemiology, which we review in this article. However, it is rarely used in practice, due to a lack of off-the-s...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,评审

    doi:10.1093/aje/kwx347

    authors: Dukes O,Vansteelandt S

    更新日期:2018-05-01 00:00:00