"If it isn't ultimately aimed at policy, it's not worth doing": interview of George W. Comstock by Alfredo Morabia.

Abstract:

:George W. Comstock (1915-2007), MD, MPH, DrPH, was lecturer and then professor of epidemiology at the Johns Hopkins University School of Hygiene and Public Health from 1956 to 2007 and served as editor-in-chief of the American Journal of Epidemiology from 1979 to 1988. This interview of George W. Comstock took place in Hagerstown, Maryland, in the spring of 1990. The selection of questions and answers published here represent approximately 10% of the whole interview, which had been reviewed and hand-corrected by Dr. Comstock. He first describes how epidemiology was taught at Hopkins in the 1950s and 1960s. He then distinguishes "epidemiology per se" from a "practical epidemiology" that works closely with local health departments, and he finally expresses his wish that in the future, epidemiology would become more widely involved in policy and accepted by policy makers.

journal_name

Am J Epidemiol

authors

Morabia A

doi

10.1093/aje/kwt027

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

595-600

issue

7

eissn

0002-9262

issn

1476-6256

pii

kwt027

journal_volume

177

pub_type

传,历史文章,面试
  • Traumatic spinal cord injury in Olmsted County, Minnesota, 1935-1981.

    abstract::The incidence rate for acute traumatic spinal cord injury in Olmsted County, Minnesota, for 1935-1981, standardizing for age, sex, and calendar year, was 54.8 per million person-years--83.4 for males and 27.7 for females. Thirty-eight per cent of cases died prior to hospitalization. The annual incidence rate for those...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114058

    authors: Griffin MR,Opitz JL,Kurland LT,Ebersold MJ,O'Fallon WM

    更新日期:1985-06-01 00:00:00

  • Early life infections and onset of puberty: evidence from Hong Kong's children of 1997 birth cohort.

    abstract::As economic development increases, puberty occurs at younger ages, and this could contribute to an increase in the incidence of cardiovascular diseases and hormone-related cancers. The factors that determine pubertal timing are poorly understood. The growth axis that is active during puberty is active in the first 6 m...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwr028

    authors: Kwok MK,Leung GM,Lam TH,Schooling CM

    更新日期:2011-06-15 00:00:00

  • Reporting of industrial accidents in The Netherlands.

    abstract::The true number of industrial accidents followed by absence from work in the Netherlands in 1993 has been estimated by using a capture-recapture approach. A government safety register noted 29,685 cases reported by Dutch companies. The statutory organization that insures employees of the same companies against absence...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009622

    authors: van Charante AW,Mulder PG

    更新日期:1998-07-15 00:00:00

  • A cohort analysis of lung cancer and smoking in British males.

    abstract::Lung cancer mortality in England and Wales among males in the age group 25 to 84 over the years 1941 to 1975 was analyzed. Using cigarette consumption information from the Tobacco Research Council and a statistical model, relative and attributable risks were estimated. The lung cancer deaths could be partitioned into ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113779

    authors: Stevens RG,Moolgavkar SH

    更新日期:1984-04-01 00:00:00

  • Eczema, birth order, and infection.

    abstract::The association between infections occurring in the first 2 years of life and development of eczema was investigated in 1,782 control children from a national population-based case-control study in the United Kingdom conducted over the period 1991-1996. Dates of eczema and infectious diagnoses were ascertained from co...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwn042

    authors: Hughes AM,Crouch S,Lightfoot T,Ansell P,Simpson J,Roman E

    更新日期:2008-05-15 00:00:00

  • Detecting and exploiting etiologic heterogeneity in epidemiologic studies.

    abstract::Contemporary searches for new risk factors frequently involve genome-wide explorations of very large numbers of candidate risk variants. Given that diseases can often be classified into subtypes that possess evidence of etiologic heterogeneity, the question arises as to whether or not a search for new risk factors wou...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kws128

    authors: Begg CB,Zabor EC

    更新日期:2012-09-15 00:00:00

  • Diet and physical activity as determinants of hyperinsulinemia: the Zutphen Elderly Study.

    abstract::The relation of dietary factors and physical activity to hyperinsulinemia was examined in 389 men aged 70-89 years who participated in the Zutphen Elderly Study in 1990. Information about the usual diet was obtained using a cross-check dietary history, and habitual physical activity was assessed using a validated ques...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117257

    authors: Feskens EJ,Loeber JG,Kromhout D

    更新日期:1994-08-15 00:00:00

  • Maternal exercise during pregnancy, physical fitness, and fetal growth.

    abstract::The value of exercise during pregnancy is controversial; both benefits and risks have been hypothesized. As empiric evidence is scant, the issue was investigated in a prospective study that assessed the impact on fetal growth of maternal exercise in each trimester of pregnancy. A cohort of over 800 prenatal patients w...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116614

    authors: Hatch MC,Shu XO,McLean DE,Levin B,Begg M,Reuss L,Susser M

    更新日期:1993-05-15 00:00:00

  • An epidemic of gastroenteritis traced to a contaminated public water supply.

    abstract::Between January 1 and March 15, 1974, approximately 1200 cases of acute gastrointestinal illness occurred in Richmond Heights, Florida, a residential community of 6500 in south Dade County. Over one-third of all families in the area had at least one member affected. The findings of 10 culture-proven cases of shigellos...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112238

    authors: Weissman JB,Craun GF,Lawrence DN,Pollard RA,Saslaw MS,Gangarosa EJ

    更新日期:1976-04-01 00:00:00

  • Epidemiology of taeniasis and cysticercosis in a Peruvian village. The Cysticercosis Working Group in Peru.

    abstract::To determine the prevalence of cysticercosis in a rural area where the disease is endemic, the authors studied the seroepidemiology of human and porcine cysticercosis in a Peruvian jungle community (Maceda, Peru) in 1988 using an enzyme-linked immunoelectrotransfer blot (EITB) assay. Of the 371 sampled inhabitants, 30...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116383

    authors: Diaz F,Garcia HH,Gilman RH,Gonzales AE,Castro M,Tsang VC,Pilcher JB,Vasquez LE,Lescano M,Carcamo C

    更新日期:1992-04-15 00:00:00

  • Risk of second primary malignancies in women with papillary thyroid cancer.

    abstract::Second malignancies in women diagnosed with thyroid cancer are of concern given the young average age at diagnosis and excellent survival. Data from the California Cancer Registry were used to evaluate the risk of second primary cancers among a retrospective population-based cohort of 10,932 women diagnosed with papil...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj072

    authors: Canchola AJ,Horn-Ross PL,Purdie DM

    更新日期:2006-03-15 00:00:00

  • The effects of measurement errors on relative risk regressions.

    abstract::This paper concerns the effects of random error in numerical measurements of risk factors (covariates) in relative risk regressions. When not dependent on outcome (nondifferential), such error usually attenuates relative risk estimates (shifts them toward one) and leads to spuriously narrow confidence intervals. The p...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115761

    authors: Armstrong BG

    更新日期:1990-12-01 00:00:00

  • Factors associated with earthquake deaths in the great Hanshin-Awaji earthquake, 1995.

    abstract::The authors conducted descriptive and case-control studies to find factors associated with earthquake deaths due to the Great Hanshin-Awaji earthquake on January 17, 1995, in Nishinomiya, Japan. In the case-control study, cases included all 1,104 deaths. Controls were randomly selected from survivors. Earthquake morta...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/153.2.153

    authors: Osaki Y,Minowa M

    更新日期:2001-01-15 00:00:00

  • Childhood polymyositis: a case-control study.

    abstract::A case-control epidemiologic study of childhood polymyositis is presented. Parents of 42 cases of childhood polymyositis were interviewed along with parents of controls matched for sex and age. Extensive review of past medical history, animal exposure history, residential and family history, and immunization history f...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112341

    authors: Koch MJ,Brody JA,Gillespie MM

    更新日期:1976-12-01 00:00:00

  • Risk factors for nosocomial urinary tract infection.

    abstract::In a prospective study carried out in June 1979-April 1981, 134 of 1,458 adult inpatients at New England Deaconess Hospital, Boston, Massachusetts, acquired 136 urinary tract infections during 1,474 indwelling bladder catheterizations. Multiple logistic regression analysis identified nine factors that were significant...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114487

    authors: Platt R,Polk BF,Murdock B,Rosner B

    更新日期:1986-12-01 00:00:00

  • Dietary intake of methylmercury as a correlate of gestational length and birth weight among newborns in Greenland.

    abstract::Between January 1983 and December 1986, a total of 376 mothers living in Godthaab and Thule, Greenland, were asked about their average weekly intake of marine food. The blood methylmercury concentrations of mothers and offspring were measured. Mean methylmercury concentrations in infants were found to be 40 percent hi...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115660

    authors: Foldspang A,Hansen JC

    更新日期:1990-08-01 00:00:00

  • Receiver operating characteristic curve inference from a sample with a limit of detection.

    abstract::The receiver operating characteristic curve is a commonly used tool for evaluating biomarker usefulness in clinical diagnosis of disease. Frequently, biomarkers being assessed have immeasurable or unreportable samples below some limit of detection. Ignoring observations below the limit of detection leads to negatively...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwk011

    authors: Perkins NJ,Schisterman EF,Vexler A

    更新日期:2007-02-01 00:00:00

  • Tracking strategies involving fourteen sources for locating a transient study sample: parents of sudden infant death syndrome infants and control infants.

    abstract::Strategies involving 14 sources were used to locate 230 parents of sudden infant death syndrome infants who died in Southern California between 1989 and 1992 and 255 parents of healthy, living infants matched by birth hospital, birth date, race and sex. The sample consisted of adults of reproductive age residing in So...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008859

    authors: Klonoff-Cohen H

    更新日期:1996-07-01 00:00:00

  • Maternal bereavement during pregnancy and the risk of stillbirth: a nationwide cohort study in Sweden.

    abstract::Increasing evidence suggests that maternal stress during pregnancy may influence pregnancy outcomes. In a nationwide Swedish study including almost 3 million births taking place during 1973-2006, we investigated whether maternal bereavement during pregnancy is associated with stillbirth risk. Through individual record...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kws383

    authors: László KD,Svensson T,Li J,Obel C,Vestergaard M,Olsen J,Cnattingius S

    更新日期:2013-02-01 00:00:00

  • Immunogenicity and safety of a plasma-derived heat-inactivated hepatitis B vaccine (CLB). Studies in volunteers at a low risk of infection with hepatitis B virus.

    abstract::The safety and immunogenicity of a plasma-derived heat-inactivated hepatitis B vaccine (CLB) were evaluated in 471 healthy human volunteers, who, both in their occupations and in their private lives, had been at minimal risk of being infected with hepatitis B virus. The first 202 individuals received three 3-microgram...

    journal_title:American journal of epidemiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/oxfordjournals.aje.a113936

    authors: Lelie PN,Reesink HW,de Jong-van Manen ST,Dees PJ,Reerink-Brongers EE

    更新日期:1984-11-01 00:00:00

  • Risk factors for fatal childhood diarrhea: a case-control study from two remote Panamanian islands.

    abstract::Between September 1979 and March 1980, distinguishing features between fatal and nonfatal cases of diarrhea caused by the same etiologic agents were sought in a case-control investigation of Cuna Indian children living on the San Blas Islands located off Panama's Caribbean coast. The eight fatal cases of diarrhea (fou...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114039

    authors: Ryder RW,Reeves WC,Sack RB

    更新日期:1985-04-01 00:00:00

  • Electric blanket use and breast cancer risk among younger women.

    abstract::To investigate whether use of electric blankets, one of the largest sources of electromagnetic field exposure in the home, is associated with the risk of female breast cancer, the authors analyzed data from a population-based US case-control study. The 2,199 case patients were under age 55 years and had been newly dia...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/oxfordjournals.aje.a009681

    authors: Gammon MD,Schoenberg JB,Britton JA,Kelsey JL,Stanford JL,Malone KE,Coates RJ,Brogan DJ,Potischman N,Swanson CA,Brinton LA

    更新日期:1998-09-15 00:00:00

  • The association between physical activity and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis.

    abstract::Prior reports regarding the association between physical activity and subclinical cardiovascular disease have not been consistent. The authors assessed physical activity and walking pace via questionnaire among 6,482 US adults aged 45-84 years without prior clinical cardiovascular disease participating in the Multi-Et...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwn350

    authors: Bertoni AG,Whitt-Glover MC,Chung H,Le KY,Barr RG,Mahesh M,Jenny NS,Burke GL,Jacobs DR

    更新日期:2009-02-15 00:00:00

  • Air pollution and hospital admissions for cardiovascular disease in Detroit, Michigan.

    abstract::In the December 1952 smog disaster in London, a substantial increase in mortality was closely associated with the increase in air pollution. Deaths from cardiovascular causes were elevated as well as respiratory deaths. The increase was greatest in the elderly. Hospital admissions were increased for both respiratory a...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117541

    authors: Schwartz J,Morris R

    更新日期:1995-07-01 00:00:00

  • Low dehydroepiandrosterone and ischemic heart disease in middle-aged men: prospective results from the Massachusetts Male Aging Study.

    abstract::The adrenal steroid dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) have been characterized as "protective" against ischemic heart disease (IHD), especially in men, on the basis of sparse epidemiologic evidence. The authors used data from the Massachusetts Male Aging Study, a random sample prospective study of 1...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/153.1.79

    authors: Feldman HA,Johannes CB,Araujo AB,Mohr BA,Longcope C,McKinlay JB

    更新日期:2001-01-01 00:00:00

  • Genetic variation in the progesterone receptor gene and ovarian cancer risk.

    abstract::Evidence suggests a role for progesterone in ovarian cancer development. Progesterone exerts its effect on target cells by interacting with its receptor. Thus, genetic variations that may cause alterations in the biologic functions of the progesterone receptor can potentially contribute to individual susceptibility to...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwi064

    authors: Terry KL,De Vivo I,Titus-Ernstoff L,Sluss PM,Cramer DW

    更新日期:2005-03-01 00:00:00

  • Coronary heart disease prevalence and its relation to risk factors in American Indians. The Strong Heart Study.

    abstract::Although coronary heart disease (CHD) is currently the leading cause of death among American Indians, information on the prevalence of CHD and its association with known cardiovascular risk factors is limited. The Strong Heart Study was initiated in 1988 to quantify cardiovascular disease and its risk factors among th...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117632

    authors: Howard BV,Lee ET,Cowan LD,Fabsitz RR,Howard WJ,Oopik AJ,Robbins DC,Savage PJ,Yeh JL,Welty TK

    更新日期:1995-08-01 00:00:00

  • The emergence of infection surveillance and control programs in US hospitals: an assessment, 1976.

    abstract::To assess the current state of hospitals' infection surveillance and control programs (ISCPs) nationwide and to provide a sampling frame for selecting hospitals for later phases of the SENIC Project, the authors mailed a screening questionnaire in March, 1976, to virtually all US hospitals; 86% of those in the SENIC t...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112935

    authors: Haley RW,Shachtman RH

    更新日期:1980-05-01 00:00:00

  • Relation of education and occupation-based socioeconomic status to incident Alzheimer's disease.

    abstract::In this study, the authors evaluated whether the association between low educational level and increased risk of Alzheimer's disease (AD) and dementia may be explained by occupation-based socioeconomic status (SES). A cohort of 931 nondemented subjects aged > or = 75 years from the Kungsholmen Project, Stockholm, Swed...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh018

    authors: Karp A,Kåreholt I,Qiu C,Bellander T,Winblad B,Fratiglioni L

    更新日期:2004-01-15 00:00:00

  • Acute myocardial infarction in Scottish military veterans: a retrospective cohort study of 57,000 veterans and 173,000 matched nonveterans.

    abstract::Few studies of veterans have examined cardiovascular disease as the primary outcome, other than in relation to specific conflicts or hazards. To assess the long-term risk and prognosis of acute myocardial infarction (AMI) in United Kingdom veterans from a broad range of military backgrounds and experience, we conducte...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwu082

    authors: Bergman BP,Mackay DF,Pell JP

    更新日期:2014-06-15 00:00:00