Abstract：
:The authors report the results of a case-cohort study of 338 lung cancer deaths in 1950-1988 and a random sample (sub-cohort) of 1,138 from among 16,297 men who had worked at least one year between 1950 and 1979 in manual jobs at a large aluminum production plant. In the past, certain workers were exposed to substantial quantities of coal tar pitch volatiles, a mixture known to include polynuclear (polycyclic) aromatic hydrocarbons, and thus suspected to be capable of causing lung cancer. After they controlled for the effects of smoking, the authors found that rate ratios rose with cumulative exposure to coal tar pitch volatiles measured as benzene-soluble material to 2.25 (95% confidence interval (CI) 1.50-3.38) at 10-19 mg/m3-years benzene-soluble matter, but did not rise further at higher exposures. The data are compatible with a linear relation with benzene-soluble matter (rate ratio (RR) = 1 + 0.031 mg/m3-years benzene-soluble matter). This model predicts a rate ratio of 1.25, and lifelong excess risk of 2.2%, after 40 years exposure at the current hygiene standard (0.2 mg/m3). A curved relation (RR = 1 + 0.098 mg/m3-years benzene-soluble matter 0.7) fitted somewhat better. Under this model, the predicted risks after this exposure are higher: 1.42 and 3.8%. The data are compatible with both additive and multiplicative models for the combined effect of smoking and coal tar pitch volatiles.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Armstrong B,Tremblay C,Baris D,Thériault Gdoi
10.1093/oxfordjournals.aje.a116992subject
Has Abstractpub_date
1994-02-01 00:00:00pages
250-62issue
3eissn
0002-9262issn
1476-6256journal_volume
139pub_type
杂志文章abstract：:In this study, we assessed the association of chronic medical conditions and multimorbidity with perceived stress among community-dwelling adults in 44 low- and middle-income countries. Data from the World Health Survey (2002-2004), including 229,293 adults, were analyzed. A perceived stress score (range, 0 (lowest st...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwx159
更新日期：2017-10-15 00:00:00
abstract：:Cigarette smoking is irrefutably the strongest risk factor for lung cancer; however, approximately 25% of cases worldwide occur among nonsmokers. The age-adjusted annual incidence rate of lung cancer in Shanghai, a region where relatively few women smoke cigarettes, is one of the highest in the world. To help further ...
journal_title：American journal of epidemiology
pub_type： 杂志文章,多中心研究
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更新日期：2008-12-01 00:00:00
abstract：:The association between serum selenium concentration and five-year risk of cardiovascular disease was studied in 1,110 men aged 55 to 74 years in two rural areas of Finland. In the total cohort, all-cause and cardiovascular deaths were associated significantly with serum selenium of less than 45 micrograms/liter, an a...
journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：1985-08-01 00:00:00
abstract：:Population-based disease registries for acquired immunodeficiency syndrome (AIDS) and cancer were linked for San Francisco residents to study the pattern of AIDS-associated malignancies diagnosed during the time period 1980-1987. A total of 1,756 newly diagnosed malignancies were identified during these years among me...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116598
更新日期：1993-01-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112686
更新日期：1979-03-01 00:00:00
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更新日期：1980-02-01 00:00:00
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pub_type： 杂志文章
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更新日期：1981-09-01 00:00:00
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journal_title：American journal of epidemiology
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更新日期：2020-08-01 00:00:00
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更新日期：1999-10-01 00:00:00
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更新日期：2013-05-15 00:00:00
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journal_title：American journal of epidemiology
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更新日期：1982-12-01 00:00:00
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更新日期：1982-09-01 00:00:00
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更新日期：2002-04-01 00:00:00
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journal_title：American journal of epidemiology
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更新日期：2002-09-01 00:00:00
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更新日期：1985-01-01 00:00:00
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更新日期：1999-05-01 00:00:00
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journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwj079
更新日期：2006-04-01 00:00:00
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更新日期：2018-03-01 00:00:00
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journal_title：American journal of epidemiology
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更新日期：2017-06-15 00:00:00
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更新日期：2012-08-01 00:00:00
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更新日期：2003-03-15 00:00:00
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更新日期：1985-11-01 00:00:00
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journal_title：American journal of epidemiology
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journal_title：American journal of epidemiology
pub_type： 杂志文章
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更新日期：1984-04-01 00:00:00
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journal_title：American journal of epidemiology
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doi：10.1093/aje/kwp460
更新日期：2010-04-01 00:00:00
