Mold and human health: separating the wheat from the chaff.

abstract：:Patients presenting to the emergency department (ED) or clinic with acute exacerbation of asthma (AEA) can be very challenging varying in both severity and response to therapy. High-dose, frequent or continuous nebulized short-acting beta2 agonist (SABA) therapy that can be combined with a short-acting muscarinic anta...

journal_title：Clinical reviews in allergy & immunology

authors： Albertson TE,Sutter ME,Chan AL

更新日期：2015-02-01 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic disease of the liver and bile ducts that is associated with inflammatory bowel disease, generally leads to end-stage liver disease, and is complicated by malignancies of the biliary tree and the large intestine. The pathogenesis of PSC remains enigmati...

journal_title：Clinical reviews in allergy & immunology

authors： Beuers U,Kullak-Ublick GA,Pusl T,Rauws ER,Rust C

更新日期：2009-02-01 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a rare inflammatory liver disease for which ursodeoxycholic acid (UDCA) is the only therapy approved by the U.S. Food and Drug Administration. Patients with a biochemical response to UDCA therapy have a similar survival rate compared to the general population. However, up to 40% of P...

journal_title：Clinical reviews in allergy & immunology

authors： Floreani A,Franceschet I,Perini L,Cazzagon N,Gershwin ME,Bowlus CL

更新日期：2015-06-01 00:00:00

abstract：:Acid anhydrides are used by chemical industries as plasticizers. Trimellitic acid (TMA) is an acid anhydride widely utilized in factories to produce paints, varnishes, and plastics. In addition to causing direct irritant effects, TMA can augment antibody responses in exposed factory workers leading to occupational ast...

journal_title：Clinical reviews in allergy & immunology

authors： Ghosh D,Bernstein JA

更新日期：2020-08-01 00:00:00

abstract：:Reduced bone mineral density is frequently found especially in adult celiac disease (CD) and dietary guidelines favor vitamin D supplementation in adults and children with CD. Vitamin D serum levels were investigated in CD populations in order to challenge its routine supplementation. Israeli (61), Spanish (59), CD ch...

journal_title：Clinical reviews in allergy & immunology

authors： Lerner A,Shapira Y,Agmon-Levin N,Pacht A,Ben-Ami Shor D,López HM,Sanchez-Castanon M,Shoenfeld Y

更新日期：2012-06-01 00:00:00

abstract：:As physiological pathways of intercellular communication produced by all cells, cytokines are involved in the pathogenesis of inflammatory insulitis as well as pivotal mediators of immune homeostasis. Proinflammatory cytokines including interleukins, interferons, transforming growth factor-β, tumor necrosis factor-α, ...

journal_title：Clinical reviews in allergy & immunology

authors： Kaminitz A,Ash S,Askenasy N

更新日期：2017-06-01 00:00:00

abstract：:AECAs have been found in 26% of patients with uveoretinitis in studies arising from three different laboratories, and their presence cannot simply be explained by coexisting extraocular disease. There is little correlation with ocular disease activity or other markers of systemic inflammation and vascular damage that ...

journal_title：Clinical reviews in allergy & immunology

authors： Edelsten C,D'Cruz DP

更新日期：1997-04-01 00:00:00

abstract：:Over the years, the commonly used term to describe juvenile idiopathic arthritis (JIA) has changed. By definition, JIA includes all types of arthritis with no apparent cause, lasting more than 6 weeks, in patients aged less than 16 years at onset. JIA pathogenesis is still poorly understood: the interaction between en...

journal_title：Clinical reviews in allergy & immunology

authors： Rigante D,Bosco A,Esposito S

更新日期：2015-10-01 00:00:00

abstract：:Prognosis of several autoimmune diseases, especially rheumatoid arthritis (RA), ankylosing spondylitis, Crohn's disease (CD), and psoriasis, usually refractory to conventional treatment improved considerably with the introduction of tumor necrosis factor alpha (TNF-alpha) antagonistic agents, which is now available (i...

journal_title：Clinical reviews in allergy & immunology

authors： Emi Aikawa N,de Carvalho JF,Artur Almeida Silva C,Bonfá E

更新日期：2010-04-01 00:00:00

abstract：:Omalizumab is a humanized mouse monoclonal antibody that binds specifically to the constant region of the immunoglobulin (Ig)E heavy chain. Omalizumab exerts its effects by reducing free serum IgE levels and FcepsilonRI expression on several cell types. These effects have been shown to result in decreased airway infla...

journal_title：Clinical reviews in allergy & immunology

authors： Chiang DT,Clark J,Casale TB

更新日期：2005-08-01 00:00:00

abstract：:Biological rhythms are fundamental for homeostasis and have recently been involved in the regulatory processes of various organs and systems. Circadian cycle proteins and hormones have a direct effect on the inflammatory response and have shown pro- or anti-inflammatory effects in animal models of autoimmune diseases....

journal_title：Clinical reviews in allergy & immunology

authors： Torres-Ruiz J,Sulli A,Cutolo M,Shoenfeld Y

更新日期：2017-08-01 00:00:00

abstract：:Every 2 years, an International Congress of Autoimmunity is organized and held with the intent of creating a new base for continuing interdisciplinary and international research, including further opportunities to train in the field of autoimmunity. In September 2008, the Congress of Autoimmunity was held in Porto, Po...

journal_title：Clinical reviews in allergy & immunology

authors： Matthias T,Shoenfeld Y

更新日期：2010-04-01 00:00:00

abstract：:Pulmonary function testing is useful for the diagnosis and management of a variety of pulmonary conditions, and the most commonly obtained component is spirometry. Spirometry is most useful in the evaluation of obstructive airway disorders but can be a helpful tool in the management of patients with chest restriction ...

journal_title：Clinical reviews in allergy & immunology

authors： Liou TG,Kanner RE

更新日期：2009-12-01 00:00:00

abstract：:To investigate the prevalence of anti-third generation cyclic citrullinated peptide antibodies (anti-CCP3) in patients with systemic connective tissue diseases, we assembled a training set consisting of 115 patients with rheumatoid arthritis (RA), 52 with Calcinosis, Raynaud's phenomenon, oesophageal dysmotility, scle...

journal_title：Clinical reviews in allergy & immunology

authors： Wu R,Shovman O,Zhang Y,Gilburd B,Zandman-Goddard G,Shoenfeld Y

更新日期：2007-02-01 00:00:00

abstract：:Contact dermatitis accounts for 95% of occupational skin disorders. Irritant contact dermatitis (ICD) is often caused by cumulative exposure to weak irritants, accounting for 80% of all cases of contact dermatitis. ICD can co-exist with atopic dermatitis (AD) and allergic contact dermatitis (ACD). Patients with AD and...

journal_title：Clinical reviews in allergy & immunology

authors： Bains SN,Nash P,Fonacier L

更新日期：2019-02-01 00:00:00

abstract：:Wegener's granulomatosis (WG) is a chronic, relapsing, systemic necrotizing vasculitis with typical pathologic findings of granulomatous inflammation and pauci-immune vasculitis. Untreated, the condition has a very high mortality, and contemporary treatment strategies carry a high risk of treatment-related morbidity. ...

journal_title：Clinical reviews in allergy & immunology

authors： Hinze CH,Colbert RA

更新日期：2008-06-01 00:00:00

abstract：:The functions of macrophages that lead to effective host responses are critical for protection against Staphylococcus aureus. Deep tissue-invading S. aureus initially countered by macrophages trigger macrophage accumulation and induce inflammatory responses through surface receptors, especially toll-like receptor 2 (T...

journal_title：Clinical reviews in allergy & immunology

authors： Wang YC,Ma HD,Yin XY,Wang YH,Liu QZ,Yang JB,Shi QH,Sun B,Gershwin ME,Lian ZX

更新日期：2016-12-01 00:00:00

abstract：:The Zika virus outbreaks highlight the growing importance need for a reliable, specific and rapid diagnostic device to detect Zika virus, as it is often recognized as a mild disease without being identified. Many Zika virus infection cases have been misdiagnosed or underreported because of the non-specific clinical pr...

journal_title：Clinical reviews in allergy & immunology

authors： Maharajan MK,Ranjan A,Chu JF,Foo WL,Chai ZX,Lau EY,Ye HM,Theam XJ,Lok YL

更新日期：2016-12-01 00:00:00

abstract：:Bronchial hyperresponsiveness (BHR) is a characteristic feature of asthma, and individuals with this disease respond to a range of physiological and chemical insults that are otherwise innocuous to healthy subjects, suggesting that the mechanisms underlying this phenomenon are characteristic of the asthma phenotype. B...

journal_title：Clinical reviews in allergy & immunology

authors： Page CP,Spina D

更新日期：2006-10-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder with a broad spectrum of clinical presentations and association with multiple immunological abnormalities. Recent research of the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway-revealed aberrant STAT s...

journal_title：Clinical reviews in allergy & immunology

authors： Goropevšek A,Holcar M,Avčin T

更新日期：2017-04-01 00:00:00

abstract：:In the vast database of peer-reviewed articles, the number of 2018 papers published retrieved using the "autoimmunity" keyword remained unchanged compared with the brilliant results of 2017 while returning above a 5% share within the immunology field, after the brisk decrease of this ratio in 2017. As in the past 12 y...

journal_title：Clinical reviews in allergy & immunology

authors： Selmi C

更新日期：2019-06-01 00:00:00

abstract：:Available data on small numbers of patients with refractory and/or relapsing Wegener's granulomatosis support very good overall outcomes with rituximab, an anti-CD20 biotherapy targeting B cells, in combination with ongoing immunosuppressants, apparently independently of antineutrophil cytoplasm antibody (ANCA) status...

journal_title：Clinical reviews in allergy & immunology

authors： Aouba A,Pagnoux C,Bienvenu B,Mahr A,Guillevin L

更新日期：2008-02-01 00:00:00

abstract：:Sarcoidosis is a systemic granulomatous disease that frequently involves the lung. Although classically thought of as a restrictive lung disease, airway obstruction has become a recognized feature of the disease in the past years. Sarcoidosis can affect the airway at any level and when the involvement includes small a...

journal_title：Clinical reviews in allergy & immunology

authors： Laohaburanakit P,Chan A

更新日期：2003-10-01 00:00:00

abstract：:It has been shown that many hereditary motor neuron diseases are caused by mutation of RNA processing enzymes. Survival of motor neuron 1 (SMN1) is well-known as a causative gene for spinal muscular atrophy (SMA) and mutations of glycyl- and tyrosyl-tRNA synthetases are identified as a cause of distal SMA and Charcot-...

journal_title：Clinical reviews in allergy & immunology

authors： Satoh M,Ceribelli A,Chan EK

更新日期：2012-02-01 00:00:00

abstract：:G protein-coupled receptors (GPCRs) constitute the largest family of plasma membrane receptors in nature and mediate the effects of a variety of extracellular signals, such as hormone, neurotransmitter, odor, and light signals. Due to their involvement in a broad range of physiological and pathological processes and t...

journal_title：Clinical reviews in allergy & immunology

authors： Zhao M,Wang Z,Yang M,Ding Y,Zhao M,Wu H,Zhang Y,Lu Q

更新日期：2021-01-07 00:00:00

abstract：:The number of peer-reviewed articles published during the 2017 solar year and retrieved using the "autoimmunity" key word increased significantly compared to 2016 while maintaining a stable share within the immunology field, following years with alternated fortunes. A detailed arbitrary analysis of the published artic...

journal_title：Clinical reviews in allergy & immunology

authors： Selmi C

更新日期：2018-12-01 00:00:00

abstract：:Although allergic asthma was described to be associated with the presence of mucosal T helper (Th)2 cells, it is not entirely clear which factors are responsible for priming of T cells to differentiate into Th2 effector cells in this disease. Interleukin (IL)-6 has been recognized as important because it is secreted b...

journal_title：Clinical reviews in allergy & immunology

authors： Doganci A,Sauer K,Karwot R,Finotto S

更新日期：2005-06-01 00:00:00

abstract：:Resolvins, belonging to the group of specialized proresolving mediators (SPMs), are metabolic products of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and are synthesized during the initial phases of acute inflammatory responses to promote the resolution of inflammation. Resolvins are produced for termination of ne...

journal_title：Clinical reviews in allergy & immunology

authors： Abdolmaleki F,Kovanen PT,Mardani R,Gheibi-Hayat SM,Bo S,Sahebkar A

更新日期：2020-02-01 00:00:00

abstract：:Asthma is the most common potentially serious medical problem to complicate pregnancy. Recent reports suggest that 7 of every 100 pregnant women suffer from asthma during pregnancy. Asthmatic women have been shown to be at an increased risk of complications during pregnancy. This may be secondary to inadequately contr...

journal_title：Clinical reviews in allergy & immunology

authors： Namazy JA,Schatz M

更新日期：2004-06-01 00:00:00

abstract：:During the last decade, B regulatory cells are appreciated to have a central role in preventing autoimmunity and maintaining self-tolerance. They are characterized by expressing different phenotypic markers and the production of either IL-10 or TGF-β or both. The recent recognition of Fas ligand expressing B regulator...

journal_title：Clinical reviews in allergy & immunology

authors： Vadasz Z,Toubi E

更新日期：2017-06-01 00:00:00