Abstract:
:We have investigated the distribution of genotypes of a restriction fragment length polymorphism of the T-cell receptor beta-subunit gene in Caucasoid controls and patients with insulin-dependent diabetes mellitus, celiac disease, dermatitis herpetiformis, and idiopathic membranous nephropathy and also in South Indian controls and diabetics. We found no significant differences between the controls and patients with any disease in either ethnic group, a result which contrasts with previous reports of associations with both insulin-dependent diabetes mellitus and idiopathic membranous nephropathy. However, the most striking finding was a marked disparity between the genotype distribution in our Caucasoid control population and that previously reported by other investigators.
journal_name
Hum Immunoljournal_title
Human immunologyauthors
Niven MJ,Caffrey C,Moore RH,Sachs JA,Mohan V,Festenstein H,Hoover ML,Hitman GAdoi
10.1016/0198-8859(90)90086-5subject
Has Abstractpub_date
1990-04-01 00:00:00pages
360-7issue
4eissn
0198-8859issn
1879-1166pii
0198-8859(90)90086-5journal_volume
27pub_type
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