Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with spondyloarthritis.

abstract：:One of the major categories of disease-causing micro-organisms are viruses. New studies on many different viruses have shown that virus attachment and cell entry is often a multistep process, requiring many interactions between the virus and cell surface molecules. In this study, we have attempted to identify the cell...

journal_title：Human immunology

authors： Triantafilou M,Triantafilou K,Wilson KM

更新日期：2000-09-01 00:00:00

abstract：:The polymorphic MICA gene encodes glycoproteins that activate T cells and NK cells through the NKG2D receptor and may costimulate immune functions. We found that MICA was expressed on freshly isolated human fibroblasts and was markedly decreased when fibroblasts were grown to confluency in culture dishes. MICA surface...

journal_title：Human immunology

authors： Zou Y,Mirbaha F,Stastny P

更新日期：2006-03-01 00:00:00

abstract：:Attempts to predict outcome of bone marrow transplantation based on killer immunoglobulin-like receptor (KIR) and HLA genotyping have yielded discordant results. To better understand the factors involved, we investigated natural killer (NK) cell function and correlated it with genetics and expression of inhibitory KIR...

journal_title：Human immunology

authors： Han M,Fallena M,Guo Y,Stastny P

更新日期：2007-06-01 00:00:00

abstract：:This article hashas been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Human immunology

authors： Li T,Huang H,Liao D,Ling H,Su B,Cai M

更新日期：2015-11-14 00:00:00

abstract：:Despite advances in HLA matching, graft failure remains a serious complication after allogeneic hematopoietic cell transplantation (HCT). Pre-formed anti-HLA donor-specific antibodies (DSAs) have been associated with graft failure, but the impact of newly developing (de novo) anti-HLA antibodies on HCT outcomes remain...

journal_title：Human immunology

authors： Hefazi M,Hogan WJ,Wakefield LL,Gandhi MJ

更新日期：2018-12-01 00:00:00

abstract：:The influence of subtle HLA diversification on antigen binding was explored using murine L-cell transfectants expressing alleles in the DR11/DR13 family and a panel of peptides. The levels of binding among this family of DR microvariants were as diverse as the levels of binding among distantly related DR molecules. Ev...

journal_title：Human immunology

authors： Hurley CK,Steiner N

更新日期：1995-06-01 00:00:00

abstract：:A case-control study was performed to establish a potential association of two TNF-α gene promoter SNPs (-238G>A and -308G>A) with occurrence of type 1 Diabetes mellitus (T1DM) in Croatian population (174 patients and 193 healthy controls). Genotypes (obtained by polymerase chain reaction-restriction fragment length p...

journal_title：Human immunology

authors： Korolija M,Hadžija M,Medvidović EP,Pavkovic P,Kapitanović S,Renar IP,Hadžija MP

更新日期：2010-12-01 00:00:00

abstract：:The 5' cis-regulatory region of the CCR5 gene exhibits a strong signature of balancing selection in several human populations. Here we analyze the polymorphism of this region in Amerindians from Amazonia, who have a complex demographic history, including recent bottlenecks that are known to reduce genetic variability....

journal_title：Human immunology

authors： Ramalho RF,Santos EJ,Guerreiro JF,Meyer D

更新日期：2010-09-01 00:00:00

abstract：:Different human leukocyte antigen (HLA) class II alleles have been associated with the development of atopic asthma. To determine whether HLA class II alleles are associated with atopic asthma in a population from southeast Spain (Murcia region), 213 atopic asthmatic patients and 150 controls were selected for HLA typ...

journal_title：Human immunology

authors： Torío A,Sánchez-Guerrero I,Muro M,Villar LM,Minguela A,Marín L,Moya-Quiles MR,Montes-Ares O,Pagán J,Alvarez-López MR

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Tumour necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of generalized aggressive periodontitis (AgP) and chronic periodontitis (CP). The objective of the present study was to evaluate the association of four TNF-alpha gene polymorphisms (-1031T/C, -857C/T, -308G/A and -238G/A) with ...

journal_title：Human immunology

authors： Yang W,Jia Y,Wu H

更新日期：2013-12-01 00:00:00

abstract：:Antibody-mediated rejection (ABMR) is associated with poor transplant outcome. Pathogenic alloantibodies are usually directed against human leukocyte antigens (HLAs). Histological findings suggestive of ABMR usually demonstrate an anti-HLA donor-specific antibody (DSA)-mediated injury, while a small subset of patients...

journal_title：Human immunology

authors： Delville M,Charreau B,Rabant M,Legendre C,Anglicheau D

更新日期：2016-11-01 00:00:00

abstract：:The goal of this study was to evaluate the influence of KIR-HLA genotypes on the outcome of patients undergoing treatment for haematological malignancies by non-T-depleted lymphocyte haematopoietic stem cell transplantation (HSCT) from HLA-matched sibling donors. The prospective study was conducted at the Center of He...

journal_title：Human immunology

authors： Cardozo DM,Marangon AV,da Silva RF,Aranha FJP,Visentainer JEL,Bonon SHA,Costa SCB,Miranda ECM,de Souza CA,Guimarães F

更新日期：2016-10-01 00:00:00

abstract：:When lymphocytes of healthy donors were incubated with penicillin and washed before HLA typing, the cytotoxic reactivity of some typing sera with their corresponding antigen was blocked. When the penicillin was added to the cytotoxicity assay at different times, competition between penicillin and alloantiserum for bin...

journal_title：Human immunology

authors： Claas FH,Runia-van Nieuwkoop R,van den Berge W,van Rood JJ

更新日期：1982-08-01 00:00:00

abstract：:CD8(+) T-cell responses to three human cytomegalovirus (CMV) pp65 epitopes were studied in panels of healthy seropositive HLA-A*02/HLA-B*07 individuals, and HLA-A*02 donors mismatched for HLA-B*07. The majority of the latter had significant responses to a HLA-A*02-restricted epitope within the CMV pp65 antigen. By con...

journal_title：Human immunology

authors： Lacey SF,Villacres MC,La Rosa C,Wang Z,Longmate J,Martinez J,Brewer JC,Mekhoubad S,Maas R,Leedom JM,Forman SJ,Zaia JA,Diamond DJ

更新日期：2003-04-01 00:00:00

abstract：:Cord blood, donated by mothers after the birth of their children, has become an accepted source of related and unrelated hematopoietic stem cells for marrow reconstitution. We estimate that some 7-8000 unrelated-donor cord blood transplants have been performed worldwide since 1993. The development of cord blood as a s...

journal_title：Human immunology

authors： Rubinstein P

更新日期：2006-06-01 00:00:00

abstract：:Serological and immunochemical studies showed that monoclonal antibody Q2/70 (MoAb Q2/70), produced by the hybridoma technique, is specific for human Ia-like antigens. This antibody recognizes an antigenic determinant which is different from those defining the serologic polymorphism of Ia-like antigens, and is express...

journal_title：Human immunology

authors： Quaranta V,Indiveri F,Glassy MC,Ng A,Russo C,Molinaro GA,Pellegrino MA,Ferrone S

更新日期：1980-10-01 00:00:00

abstract：:Invariant natural killer T (iNKT) cells have been reported to play a role in the pathogenesis of murine asthma. However, the role for iNKT cells in the pathogenesis of human asthma is not defined. In this study we aimed to determined how blood iNKT cells are associated with atopy in asthmatic individuals. Peripheral b...

journal_title：Human immunology

authors： Koh YI,Shim JU,Wi JO,Han ER,Jin NC,Oh SH,Park CK,Park DJ

更新日期：2010-02-01 00:00:00

abstract：:DC-10 is a distinct subset of human tolerogenic dendritic cells (DCs) which express high levels of human leukocyte antigen-G (HLA-G). DC-10 could induce adaptive type 1 regulatory T cells through the IL-10 dependent ILT4/HLA-G signaling pathway. However, the significance of DC-10 in malignancies remains unclear. In th...

journal_title：Human immunology

authors： Xu DP,Shi WW,Zhang TT,Lv HY,Li JB,Lin A,Yan WH

更新日期：2016-09-01 00:00:00

abstract：:Sera obtained from multiparous women and some of other origin contain antibodies which react with antigens on T cell subsets. These antibodies recognize two distinct diallelic systems, one of which is mainly present on T gamma cells while the other is present on T mu cells. The sera that reacted with the T gamma cells...

journal_title：Human immunology

authors： van Leeuwen A,Festenstein H,van Rood JJ

更新日期：1982-04-01 00:00:00

abstract：:Population studies represent an integral part, and a necessary link in a complex chain of host-pathogen interactions, disease pathogenesis, and major histocompatibility complex polymorphism. HLA class I and class II allele and haplotype distributions among Venezuelan mestizos were determined. Genes of Mongoloid, Negro...

journal_title：Human immunology

authors： Makhatadze NJ,Franco MT,Layrisse Z

更新日期：1997-06-01 00:00:00

abstract：:CD4(+) Th2 helper cell mediated immune responses have been shown to play a crucial role in the pathogenesis of ABPA. HLA and TCR are the candidate genes, which can influence the specificity of these responses. We have previously established a strong association of HLA DR2/5 in ABPA susceptibility. The study was design...

journal_title：Human immunology

authors： Chauhan B,Hutcheson PS,Slavin RG,Bellone CJ

更新日期：2002-04-01 00:00:00

abstract：:The family of T-cell immunoglobulin domain and mucin domain (TIM) proteins is identified to be expressed on T cells. A member of Tim family, TIM-1, was considered as a membrane protein that is associated with the development of helper T cell (Th2) biased immune responses, and may be selectively expressed on Th2 cells....

journal_title：Human immunology

authors： Chae SC,Song JH,Heo JC,Lee YC,Kim JW,Chung HT

更新日期：2003-12-01 00:00:00

abstract：:A number of anti-H-2 alloantisera containing antibody reactive with I region gene products (Ia) of the major histocompatibility complex cross-react with determinants expressed by human peripheral blood B lymphocytes. Such data have led to the conclusion that Ia and DR antigens share cross-reacting determinants. We hav...

journal_title：Human immunology

authors： Shaut DM,Ireland J,Scornik JC,Peck AB

更新日期：1983-06-01 00:00:00

abstract：:Several complement regulatory proteins exist on self-cells to prevent damage by the serum complement system. In the present study, we aimed to perform quantitative analysis of membrane-bound complement regulators, CR1 (CD35), MCP (CD46), DAF (CD55), and MIRL (CD59), on peripheral blood neutrophils, monocytes, and lymp...

journal_title：Human immunology

authors： Nuutila J,Jalava-Karvinen P,Hohenthal U,Kotilainen P,Pelliniemi TT,Nikoskelainen J,Lilius EM

更新日期：2013-05-01 00:00:00

abstract：:Human leukocyte antigen-G (HLA-G) is a nonclassical class Ib molecule belonging to the major histocompatibility complex. HLA-G appears to play a role in the suppression of immune responses and contribute to long-term immune escape or tolerance. The focus of this review is polymorphism in the HLA-G gene and protein and...

journal_title：Human immunology

authors： Larsen MH,Hviid TV

更新日期：2009-12-01 00:00:00

abstract：:HLA analysis of the family of a renal transplant patient revealed an extremely rare condition. On repeated typings the only demonstrable HLA antigens shown in the propositus were from the maternal haplotype, HLA-A11,-B46,-CW1,-DR14,-DQ1. No paternal antigens could be demonstrated either by serologic or by DNA-typing m...

journal_title：Human immunology

authors： van den Berg-Loonen EM,Savelkoul P,van Hooff H,van Eede P,Riesewijk A,Geraedts J

更新日期：1996-01-01 00:00:00

abstract：:To commence proper antibiotic treatment in sepsis, timely knowledge of whether the cause of systemic infection is gram-negative (gram(-)) or gram-positive (gram(+)) bacteria in origin would be beneficial for clinicians. In this clinical prospective study, our objective was to develop a method for distinguishing betwee...

journal_title：Human immunology

authors： Nuutila J,Jalava-Karvinen P,Hohenthal U,Laitinen I,Kotilainen P,Rajamäki A,Nikoskelainen J,Lilius EM

更新日期：2009-04-01 00:00:00

abstract：:Patterns of BglII, MspI, and TaqI DP alpha and DP beta hybridizing restriction fragment length polymorphisms are compared with primed lymphocyte typing--determined specificities in 28 10th International Histocompatibility Workshop core cell lines. Correlation of specific RFLP patterns with most recognized DP types is ...

journal_title：Human immunology

authors： Easteal S,Voorhoeve AH,Zimmet P,Serjeantson SW

更新日期：1989-07-01 00:00:00

abstract：:An interesting class of immune responses is that in which an environmental agent modifies a self-protein. Heparin induced thrombocytopenia (HIT) is associated with an antibody response in which the immunogen is a self-protein, platelet factor 4 (PF4), modified by an external agent, heparin. We tested the hypothesis th...

journal_title：Human immunology

authors： Bacsi S,Geoffrey R,Visentin G,De Palma R,Aster R,Gorski J

更新日期：2001-02-01 00:00:00

abstract：:Induced Treg with the phenotype CD4(+)CD25(+)Foxp3(+)IFNγ(+) were shown to be associated with good long-term graft outcome in renal transplant recipients and inhibition of allogeneic T-cell responses in vitro. In the present study, we investigated whether apoptosis and Fas/FasL-dependent pathways contribute to the inh...

journal_title：Human immunology

authors： Daniel V,Sadeghi M,Wang H,Opelz G

更新日期：2013-02-01 00:00:00