Abstract:
:Although CUL4-containing ubiquitin ligases regulate DNA repair and DNA damage checkpoints, Liu et al. (2009) report in this issue of Molecular Cell that Cul4a-deficient mice exhibit surprising resistance to ultraviolet-induced skin tumors, providing insight into how ubiquitination regulates genome integrity.
journal_name
Mol Celljournal_title
Molecular cellauthors
Sugasawa Kdoi
10.1016/j.molcel.2009.05.009subject
Has Abstractpub_date
2009-05-14 00:00:00pages
403-4issue
4eissn
1097-2765issn
1097-4164pii
S1097-2765(09)00319-0journal_volume
34pub_type
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