The special delivery of a tail-anchored protein: why it pays to use a dedicated courier.

Abstract:

:The membrane-spanning C-terminal regions in tail-anchored proteins must be recognized and delivered posttranslationally to the endoplasmic reticulum or mitochondrial membrane. A paper in this issue of Molecular Cell (Wang et al., 2010) and another recent report (Mariappan et al., 2010) delineate early steps in this pathway.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Brodsky JL

doi

10.1016/j.molcel.2010.09.016

subject

Has Abstract

pub_date

2010-10-08 00:00:00

pages

5-7

issue

1

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(10)00744-6

journal_volume

40

pub_type

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