Abstract:
OBJECTIVES:The purpose of this study was to examine the effects of noise exposure on spatial learning and memory and associated mechanisms in the hippocampus (HIP). METHODS:Forty-eight male SD rats were grouped as: A, control; B, Morris water maze (MWM) training group; C, noise exposure group; and D, noise exposure followed by MWM training group. The influence of noise stress on spatial learning and memory in rats was assessed in hidden platform acquisition training and probe trial testing in MWM. Changes in morphology of Nissl bodies were observed in the CA1, CA3 and DG regions of HIP. In order to understand the possible mechanisms behind noise stress-induced changes, the concentration of amino acid neurotransmitters and the expression of NMDAR2B (NR2B) in HIP were also evaluated. RESULTS:After noise exposure, the performance of spatial learning and memory in group D was decreased significantly compared to group B. The concentration of glutamate was significantly increased in groups C and D, whereas GABA decreased markedly. The mean optical density of Nissl bodies in groups C and D was reduced in the CA1, DG and CA3 regions. The expression of NR2B was significantly decreased in the CA1, CA3 and DG regions in group C, and in the CA1 and CA3 regions in group D as compared with groups A and B. CONCLUSIONS:Excitotoxicity, impaired Nissl bodies and reduced expression of NR2B in rat HIP induced by chronic noise exposure might have caused the impairment of spatial learning and memory.
journal_name
J Occup Healthjournal_title
Journal of occupational healthauthors
Cui B,Wu M,She Xdoi
10.1539/joh.l8084subject
Has Abstractpub_date
2009-01-01 00:00:00pages
152-8issue
2eissn
1341-9145issn
1348-9585pii
JST.JSTAGE/joh/L8084journal_volume
51pub_type
杂志文章abstract::Objective of this study is to clarify the health-related conditions of Japanese male expatriates in Thailand. Records of Japanese male expatriates in their 30s to 50s who consulted outpatient clinics at Bangkok Hospital in 2005 were analyzed for number and type of outpatient visits then compared with data from the "Pa...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l7072
更新日期:2008-01-01 00:00:00
abstract::Systemic effects of p, p'-DDE (1, 1-dichloro-2, 2 bis (p-chlorophenyl) ethylene; DDE) on immature male rats were investigated in pubertal Wistar rats after oral administration of DDE. Special rat chow containing 125 ppm DDE (approximately 10 mg/kg DDE) had been administered daily for 42 d since 6 wk of age and its eff...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.45.223
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVES:This study aimed to investigate the association between occupational clusters and allergic rhinitis (AR). METHODS:The study was based on data from the Korean National Health and Nutrition Examination Survey (KNHANES: 2007-2015). This study included 46,965 individuals: 20,491 men and 26,474 women. AR was def...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2017-0234-OA
更新日期:2018-07-25 00:00:00
abstract:OBJECTIVES:Arsine, a potent hemolytic agent, is widely used in the semiconductor industry. We report a case of arsine poisoning confirmed by arsenic speciation analysis in serum and urine that occurred in a recycling factory. CASE:A male worker in his twenties noticed hematuria 3 h after finishing work and was admitte...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l10108
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:In order to measure occupational exposure concentrations of ethyl tertiary-butyl ether (ETBE), we developed a diffusive sampling method for monitoring ETBE and performed an ETBE exposure assessment. METHODS:The applicability of diffusive samplers was examined by exposing the samplers to ETBE vapor in test c...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.11-0111-oa
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:In this study, we focused on the qualitative and quantitative differences of the lung lesions induced by single or multiple intratracheal administration of nickel oxide nanoparticles (NiO). METHODS:Male rats were randomized into groups receiving intratracheal administrations in a single dose or two to four ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0184-OA
更新日期:2017-03-28 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate two-point discrimination (2PD) sense and kinesthetic sense dysfunctions in carpal tunnel syndrome (CTS) patients compared with a healthy group. METHODS:The 2PD sense, muscle force, and kinesthetic differentiation (KD) of strength; the range of motion in radiocarpal arti...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0108-OA
更新日期:2016-06-16 00:00:00
abstract:OBJECTIVES:It is common to find doctors working long and odd hours and many at times without rest and sleep. Despite the evidence of adverse risk, jeopardizing patient safety under the hands of fatigue doctors under such working hours has not changed in many places. It has argued that with such training and subsequent ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12121
更新日期:2020-01-01 00:00:00
abstract::Slovenia is a small, fast developing country in the EU with approximately 2,000,000 inhabitants and 700,000 employed. Occupational medicine has been present in Slovenia for as long as 500 yr. Today, 130 specialists of occupational medicine are in charge of health protection of the employed (including transport workers...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.47.193
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVE:To investigate associations of work-related stressors and their changes over time with the risk of developing metabolic syndrome (MetS) among Japanese manufacturing workers. METHODS:Participants were 1,040 employees aged 19 to 68 years who were free from MetS at baseline and completed the three year-interval...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2017-0298-OA
更新日期:2018-11-27 00:00:00
abstract:OBJECTIVE:This cross-sectional study aimed to assess fire risk in fire hazardous zones (FHZ) at the dispenser areas of gasoline stations. METHODS:There were 47 stations chosen for fire risk assessment and two zones around the dispenser area of each station were assessed. The assessments were carried out by applying th...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12137
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:We performed the current study to (1) understand the distribution of culturable airborne bacteria over a one-year monitoring period, (2) confirm places in stations where airborne bacteria are highly detected, (3) understand the factors that affect concentrations of airborne bacteria and (4) compare the distr...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.13-0055-fs
更新日期:2013-01-01 00:00:00
abstract::Due to the potential for an influenza pandemic, preparedness for infection control in healthcare settings is essential from the standpoint of occupational health for healthcare workers. We conducted questionnaire surveys among Japanese hospitals to assess preparedness at the individual and institutional levels and the...
journal_title:Journal of occupational health
pub_type: 杂志文章,多中心研究
doi:10.1539/joh.50.13
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate the effectiveness of supervised exercise among nurses conducting shift work for health promotion. METHODS:A total of 30 healthy female nurses conducting shift work participated in this study and they were randomly assigned to one of the following 2 groups: The supervised exercis...
journal_title:Journal of occupational health
pub_type: 杂志文章,随机对照试验
doi:10.1539/joh.16-0125-OA
更新日期:2017-07-27 00:00:00
abstract:OBJECTIVES:This field study aimed to determine the incidence and distribution of needlestick injuries among medical trainees at a community teaching hospital in Toronto, Canada. METHODS:The study was performed during the 2013-2015 academic years at Toronto East General Hospital (TEGH), a University of Toronto-affiliat...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0253-FS
更新日期:2017-01-24 00:00:00
abstract:OBJECTIVES:This study aimed to investigate changes in the smoking rate among Korean adults from 1998-2009 by gender and occupational groups. METHODS:Using the data from the first (1998), second (2001), third (2005) and fourth (2009) waves of the Korean National Health and Nutrition Examination Survey (KNHANES), we exa...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.12-0148-oa
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:The sum of urinary inorganic arsenic (iAs), monomethylarsonic acid (MMA), and dimethylarsinic acid (DMA) concentrations is used for the biological monitoring of occupational iAs exposure. Although DMA is a major metabolite of iAs, it is an inadequate index because high DMA levels are present in urine after s...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0241-OA
更新日期:2016-05-25 00:00:00
abstract:OBJECTIVES:Agricultural use of neonicotinoid (NEO) insecticides has been increasing in recent years, but their biological monitoring methods have been scarcely reported. In this study, we developed and validated a rapid and sensitive method for quantifying urinary NEO concentrations using high-performance liquid chroma...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.14-0077-OA
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Petrochemical industries are known as sources of many toxic chemicals. Safety and health risks of the petrochemical workers employed at Map Ta Phut Industrial Estate, located in Rayong, Thailand, are potentially high. METHODS:The research materials consisted of documents emanating from statutory reports on ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.11-0091-oa
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:Polychlorinated biphenyls (PCBs) are considered probable human carcinogens by the International Agency for Research on Cancer and one congener, PCB126, has been rated as a known human carcinogen. A period-specific job exposure matrix (JEM) was developed for former PCB-exposed capacitor manufacturing workers ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l9151
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:Presenteeism is undoubtedly a widespread phenomenon in organizations. Research on presenteeism has been conducted for decades in the broader workforce (eg, nurses, doctors, teachers, police officers). Occupational stress and turnover intention in occupational therapy have been extensively studied. However, t...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12153
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the association between skill underutilization, a psychological job stressor proposed in the NIOSH (National Institute for Occupational Safety and Health) job stress model, and the prevalence of hypertension. METHODS:We studied sitting blood pressure and fasting bloo...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.13-0146-br
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:According to some newspapers, concerns are growing over the health of local government employees in the Great East Japan Earthquake disaster areas. Concerns were consistently present after the Hanshin-Awaji and Niigata-Chuetsu earthquakes but not studied analytically. METHODS:Municipal employees responding ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.12-0095-br
更新日期:2013-01-01 00:00:00
abstract::Infrared Spectrophotometry (IR) is now widely used to determine crystalline silica in industrial dust samples. Though the IR method has many advantages when dealing with respirable dust samples, some serious analytical errors are often caused by interference minerals contamination. These minerals have a characteristic...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.45.94
更新日期:2003-03-01 00:00:00
abstract::This study was conducted on a thermal exposure chamber designed for assessing workers' thermal hazard. In order to assess the efficacy of the studied chamber, three environmental conditions were selected to simulate high, middle and low thermal impact situations, with air temperatures (Ta) of 43.12, 36.23 and 25.77 ma...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.45.153
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:Titanium dioxide nanoparticles are widely used as UV filters in cosmetics and as a photocatalyst. We evaluated pulmonary responses to different crystal forms of TiO2 nanoparticles. METHODS:We used 4 different TiO2 samples with similar specific surface areas (anatase, rutile, amorphous, and P25). Each sample ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0094-OA
更新日期:2016-11-29 00:00:00
abstract::The relationships between alcohol consumption, serum gamma-glutamyltransferase (GGT) levels, and the prevalence of major coronary risk factors were analyzed cross-sectionally in 2,399 male and 1,402 female middle-aged workers, to clarify the effects of moderate alcohol consumption on the development of the metabolic s...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.45.293
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVES:The aim of this meta-analysis is to investigate to what extent vacation has positive effects on health and well-being, how long such effects endure after work resumption, and how specific vacation activities and experiences affect these relationships. METHODS:Based on a systematic literature search (PsycInf...
journal_title:Journal of occupational health
pub_type: 杂志文章,meta分析,评审
doi:10.1539/joh.k8004
更新日期:2009-01-01 00:00:00
abstract::In Japan, consultations concerning child abuse cases are increasing rapidly, and the mental health of child-counseling office workers, who must deal with them, has emerged as an issue. To measure the state of mental health of these workers, and to clarify the characteristics of their job-related stress, we sent a ques...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.49.125
更新日期:2007-03-01 00:00:00
abstract::Using workplaces as a unit for randomization, a randomized controlled trial was conducted to determine the effects of web-based supervisor training on the subject of worksite mental health on job stressors, supervisor support and psychological distress among subordinate workers. A total of eight workplaces of a sales ...
journal_title:Journal of occupational health
pub_type: 杂志文章,随机对照试验
doi:10.1539/joh.48.28
更新日期:2006-01-01 00:00:00