Homocysteine may involve in the pathogenesis of Behcet's disease by inducing inflammation.

abstract：:Concentrations of acute phase proteins (CRP: C-reactive protein, albumin) change during surgery. We investigated the acute phase response to circumcision and the effects of anaesthesia on this response. The children were divided into four groups; group 1 (intratracheal general anaesthesia, n=40), group 2 (general anae...

journal_title：Mediators of inflammation

authors： Buyukkocak U,Caglayan F,Caglayan O,Basar M,Cakmak M,Batislam E,Ulusoy S

更新日期：2005-10-24 00:00:00

abstract：:Acute necrotizing encephalopathy (ANE) is a rare but distinctive type of acute encephalopathy with global distribution. Occurrence of ANE is usually preceded by a virus-associated febrile illness and ensued by rapid deterioration. However, the causal relationship between viral infections and ANE and the exact pathogen...

journal_title：Mediators of inflammation

authors： Wu X,Wu W,Pan W,Wu L,Liu K,Zhang HL

更新日期：2015-01-01 00:00:00

abstract：:The aim was to investigate whether bone tissue resorption in early RA is related to crepitus of the temporomandibular joint (TMJ) and systemic levels of inflammatory mediators and markers and sex steroid hormones. Twentynine women and 18 men with recently diagnosed RA were examined for TMJ bone erosions with computeri...

journal_title：Mediators of inflammation

authors： Hajati AK,Näsström K,Alstergren P,Bratt J,Kopp S

更新日期：2010-01-01 00:00:00

abstract：:Heparanase activity is correlated with the metastatic potential of several cancer cells and is a key enzyme in the breakdown of tissue barriers. It is also involved in the regulation of growth factor and cytokine activity. However, little is known about the factors that induce heparanase in cancer cells. We investigat...

journal_title：Mediators of inflammation

authors： Sasaki M,Ito T,Kashima M,Fukui S,Izumiyama N,Watanabe A,Sano M,Fujiwara Y,Miura M

更新日期：2001-10-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) remains a high morbidity and mortality disease entity in critically ill patients, despite decades of numerous investigations into its pathogenesis. To obtain global protein expression changes in acute lung injury (ALI) lung tissues, we employed a high-throughput proteomics me...

journal_title：Mediators of inflammation

authors： Liu D,Mao P,Huang Y,Liu Y,Liu X,Pang X,Li Y

更新日期：2014-01-01 00:00:00

abstract：:Interleukin 35 (IL-35) is a heterodimeric cytokine involved in the development of atherosclerosis. The aim of the present study was to establish if the polymorphisms of IL-12A and EBI3 genes that encode the IL-35 subunits are associated with the development of premature coronary artery disease (CAD) in Mexican individ...

journal_title：Mediators of inflammation

authors： Posadas-Sánchez R,Pérez-Hernández N,Angeles-Martínez J,López-Bautista F,Villarreal-Molina T,Rodríguez-Pérez JM,Fragoso JM,Posadas-Romero C,Vargas-Alarcón G

更新日期：2017-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is characterized by an abnormal cellular and cytokine infiltration of inflamed joints. This study addresses a previously unrecognized interaction between neutrophilic-myeloperoxidase (MPO) and macrophages (Mphi) which could explain the perpetuation of inflammation associated with RA. A monoar...

journal_title：Mediators of inflammation

authors： Gelderman MP,Stuart R,Vigerust D,Fuhrmann S,Lefkowitz DL,Allen RC,Lefkowitz SS,Graham S

更新日期：1998-01-01 00:00:00

abstract：:Stimulation of phosphoinositide hydrolysis in myocardium from autoimmune myocarditis mice by ThEA and histamine was assayed. Myocardium from autoimmune heart, but not the normal forms, specifically increased phosphoinositide turnover in the presence of histaminergic agonists. This increment was blocked by a specific H...

journal_title：Mediators of inflammation

authors： Goren N,Leiros CP,Sterin-Borda L,Borda ES

更新日期：1993-01-01 00:00:00

abstract：:Crohn's disease (CD) is a multifactorial chronic inflammatory bowel disease of unknown cause. The aim of the present study was to explore if mRNA over-expression of SSTR5 and CCR7 found in CD patients could be correlated to respective protein expression. When compared to healthy donors, SSTR5 was over-expressed 417 +/...

journal_title：Mediators of inflammation

authors： Taquet N,Dumont S,Vonesch JL,Hentsch D,Reimund JM,Muller CD

更新日期：2009-01-01 00:00:00

abstract：:Perinatal insults and subsequent neuroinflammation are the major mechanisms of neonatal brain injury, but there have been only scarce reports on the associations between hypoxic preconditioning and glial activation. Here we use neonatal hypoxia-ischemia brain injury model in 7-day-old rats and in vitro hypoxia model w...

journal_title：Mediators of inflammation

authors： Chen CY,Sun WZ,Kang KH,Chou HC,Tsao PN,Hsieh WS,Fu WM

更新日期：2015-01-01 00:00:00

abstract：:Autism is a neurodevelopmental disorder characterized by problems in communication, social skills, and repetitive behavior. Recent studies suggest that apoptotic and inflammatory mechanisms may contribute to the pathogenesis of this disorder. Nuclear factor-κB (NF-κB) is an important gene transcriptional factor involv...

journal_title：Mediators of inflammation

authors： Malik M,Tauqeer Z,Sheikh AM,Wen G,Nagori A,Yang K,Brown WT,Li X

更新日期：2011-01-01 00:00:00

abstract：:Adipose tissue produces a wide range of proteins that may influence the immune system. In this study, we assessed the serum levels of leptin, adiponectin, and ghrelin, in association with the measurements of body composition, in 15 female patients with various autoimmune diseases (systemic lupus erythematosus, primary...

journal_title：Mediators of inflammation

authors： Toussirot E,Gaugler B,Bouhaddi M,Nguyen NU,Saas P,Dumoulin G

更新日期：2010-01-01 00:00:00

abstract：:The most frequent pathogen that causes bacterial meningitis is the Gram-positive bacterium Streptococcus pneumoniae. By entering the brain, host cells will be activated and proinflammatory cytokines like interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) are released. The goal of the current study was to examine...

journal_title：Mediators of inflammation

authors： Albrecht LJ,Tauber SC,Merres J,Kress E,Stope MB,Jansen S,Pufe T,Brandenburg LO

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Exhaled nitric oxide (FeNO) has been reported to be elevated in the oxidative stress involved in asthmatic patients, and the reaction of nitric oxide (NO) with superoxide anions results in the formation of nitrotyrosine. The purpose of this study was to investigate the effect of inhaled steroid treatment on ...

journal_title：Mediators of inflammation

authors： Bodini A,Peroni DG,Zardini F,Corradi M,Alinovi R,Boner AL,Piacentini GL

更新日期：2006-01-01 00:00:00

abstract：:Syndecan-1 (CD138) is a transmembrane heparin sulfate proteoglycan expressed on distinct stages of differentiation of B-lymphoid cells. Its prognostic value in B-cell chronic lymphocytic leukemia (B-CLL) has not been evaluated so far. The serum concentration of sCD138 and some angiogenesis-involved cytokines: vascular...

journal_title：Mediators of inflammation

authors： Wołowiec D,Dybko J,Wróbel T,Urbaniak-Kujda D,Jaźwiec B,Tomaszewska-Toporska B,Kapelko-Słowik K,Potoczek S,Kuliczkowski K

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:In this work we studied the correlation between platelet count, platelet activation, and systemic inflammation in overweight, obese, and morbidly obese individuals. METHODS AND SUBJECTS:A total of 6319 individuals participated in the study. Complete blood counts, high sensitivity C-reactive protein (hs-CRP) ...

journal_title：Mediators of inflammation

authors： Samocha-Bonet D,Justo D,Rogowski O,Saar N,Abu-Abeid S,Shenkerman G,Shapira I,Berliner S,Tomer A

更新日期：2008-01-01 00:00:00

abstract：:Matrix metalloproteinase-14 (MMP-14) promotes vulnerable plaque morphology in mice, whereas tissue inhibitor of metalloproteinases-3 (TIMP-3) overexpression is protective. MMP-14(hi) TIMP-3(lo) rabbit foam cells are more invasive and more prone to apoptosis than MMP-14(lo) TIMP-3(hi) cells. We investigated the implica...

journal_title：Mediators of inflammation

authors： Johnson JL,Jenkins NP,Huang WC,Di Gregoli K,Sala-Newby GB,Scholtes VP,Moll FL,Pasterkamp G,Newby AC

更新日期：2014-01-01 00:00:00

abstract：:Chronic pain has to be considered in all respects a debilitating disease and 10-20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study of pain, great attention...

journal_title：Mediators of inflammation

authors： Vodo S,Bechi N,Petroni A,Muscoli C,Aloisi AM

更新日期：2013-01-01 00:00:00

abstract：:In this study we demonstrated that ΔCaecm33 double mutant showed reduced biofilm formation and causes less damage to gingival mucosa tissues. This was confirmed by the reduced level of necrotic cells and Bax/Bcl2 gene expression as apoptotic markers. In contrast, parental and Caecm33 mutant strains decreased basement ...

journal_title：Mediators of inflammation

authors： Rouabhia M,Semlali A,Chandra J,Mukherjee P,Chmielewski W,Ghannoum MA

更新日期：2012-01-01 00:00:00

abstract：:Interleukin-37 (IL-37) is unique in the IL-1 family since it broadly suppresses innate immunity and elevates in humans with inflammatory and autoimmune diseases. IL-37 shows definite groups and transcripts for human IL37 gene, but it is still not completely understood the effect and mechanisms of inflammatory response...

journal_title：Mediators of inflammation

authors： Yan X,Xie B,Wu G,Hu J,Wang D,Cai X,Li J

更新日期：2019-01-08 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic demyelinating disease of the human central nervous system (CNS). The condition predominantly affects young adults and is characterised by immunological and inflammatory changes in the periphery and CNS that contribute to neurovascular disruption, haemopoietic cell invasion of targe...

journal_title：Mediators of inflammation

authors： Bolton C,Paul C

更新日期：2006-01-01 00:00:00

abstract：AIM:To determine gastric tissue lactoferrin (Lf) levels of Helicobacter pylori- (Hp-) positive and -negative patients and its effect on anemia. METHODS:Cases in which initial presentation was of abdominal pain and that were Hp-positive at endoscopy were included. Hp-positive cases and -negative controls were divided i...

journal_title：Mediators of inflammation

authors： Doğan Y,Erkan T,Önal Z,Usta M,Doğusoy G,Çokuğraş FÇ,Kutlu T

更新日期：2012-01-01 00:00:00

abstract：:Inflammation represents the immune system response to external or internal aggressors such as injury or infection in certain tissues. The body's response to cancer has many parallels with inflammation and repair; the inflammatory cells and cytokines present in tumours are more likely to contribute to tumour growth, pr...

journal_title：Mediators of inflammation

authors： Albulescu R,Codrici E,Popescu ID,Mihai S,Necula LG,Petrescu D,Teodoru M,Tanase CP

更新日期：2013-01-01 00:00:00

abstract：:Mitotic catastrophe, as defined in 2012 by the International Nomenclature Committee on Cell Death, is a bona fide intrinsic oncosuppressive mechanism that senses mitotic failure and responds by driving a cell to an irreversible antiproliferative fate of death or senescence. Thus, failed mitotic catastrophe can promote...

journal_title：Mediators of inflammation

authors： Mc Gee MM

更新日期：2015-01-01 00:00:00

abstract：:Osteoarthritis (OA) belongs to a group of degenerative diseases. Synovial inflammation, cartilage abrasion, and subchondral sclerosis are characteristics of OA. Researchers do not fully understand the exact etiology of OA. However, matrix metalloproteinases (MMPs), which are responsible for cartilage matrix degradatio...

journal_title：Mediators of inflammation

authors： Chen YT,Hou CH,Hou SM,Liu JF

更新日期：2014-01-01 00:00:00

abstract：:Periodontitis is a kind of chronic inflammatory disease that affects the tooth-supporting tissues. ET-1 is related to periodontitis and involved in the regulation of cytokines, but the mechanisms remain unclear. The aim of this study is to investigate how ET-1 affects proinflammatory cytokine expression and differenti...

journal_title：Mediators of inflammation

authors： Liang L,Zhou W,Yang N,Yu J,Liu H

更新日期：2016-01-01 00:00:00

abstract：:Cysteinyl leukotrienes (CysLTs) are potent lipid inflammatory mediators synthesized from arachidonic acid, through the 5-lipoxygenase (5-LO) pathway. Owing to their properties, CysLTs play a crucial role in the pathogenesis of inflammation; therefore, CysLT modifiers as synthesis inhibitors or receptor antagonists, ce...

journal_title：Mediators of inflammation

authors： Colazzo F,Gelosa P,Tremoli E,Sironi L,Castiglioni L

更新日期：2017-01-01 00:00:00

abstract：:As a noninvasive method, exhaled breath condensate (EBC) has gained importance to improve monitoring of lung diseases and to detect biomarkers. The aim of the study was to investigate, whether erythropoietin (EPO) is detectable in EBC. EBC was collected from 22 consecutive patients as well as from healthy individuals....

journal_title：Mediators of inflammation

authors： Schumann C,Triantafilou K,Krueger S,Hombach V,Triantafilou M,Becher G,Lepper PM

更新日期：2006-01-01 00:00:00

abstract：:Severe acute pancreatitis (SAP) characterized by atrocious progression and numerous complications often leads to a high mortality rate due to hypermetabolism, systemic inflammatory response syndrome (SIRS), and multiple organs dysfunction syndrome (MODS). Studies have revealed that both early enteral nutrition (EEN) a...

journal_title：Mediators of inflammation

authors： Wang G,Sun B,Gao Y,Meng QH,Jiang HC

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Platelet-activating factor (PAF) seems to be implicated in systemic lupus erythematosus (SLE) patients with associated renal diseases. AIMS:In this study, we ensured the role of PAF in SLE patients without renal complications. METHODS:Blood PAF and acetylhydrolase activity, plasma soluble phospholipase A(2...

journal_title：Mediators of inflammation

authors： Denizot Y,Liozon E,Guglielmi L,Ly K,Soria P,Loustaud V,Vidal E,Jauberteau MO

更新日期：2003-04-01 00:00:00