Eosinophilic globules in bronchoalveolar lavage fluid of patients with systemic sclerosis-related interstitial lung disease: a diagnostically useful, previously unreported finding in a retrospective and prospective study, including differential diagnosis

abstract：:The international sensitivity index (ISI) calibration of point-of-care-test (POCT) prothrombin time (PT) whole blood monitors is complex, requiring manual PT testing of 60 patients' and 20 healthy subjects' plasma samples. The possibility of reducing these numbers was studied by a Monte Carlo Bootstrap study for 2 POC...

journal_title：American journal of clinical pathology

authors： Poller L,Keown M,Chauhan N,van den Besselaar AM,Tripodi A,Jespersen J,Shiach C

更新日期：2002-06-01 00:00:00

abstract：:Anti-sperm antibodies from serum and seminal plasma were detected by concurrent flow cytometry and epifluorescence microscopy using fluorescein-conjugated antihuman immunoglobulins. Experimental conditions were designed, taking advantage of several monoclonal antisperm antibodies, to test aspects of the assay before c...

journal_title：American journal of clinical pathology

authors： Sinton EB,Riemann DC,Ashton ME

更新日期：1991-02-01 00:00:00

abstract：:The Sysmex R-3000 (TOA Medical Electronics, Kobe, Japan) evaluates maturation of reticulocytes by quantitating the fraction of reticulocytes within low-, middle-, and high-fluorescence intensity regions. We defined the immature reticulocyte fraction (IRF) as the sum of the fraction of high-fluorescence intensity regio...

journal_title：American journal of clinical pathology

authors： Chang CC,Kass L

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVES:Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a heterogeneous disorder defined by morphologic, genetic, or clinical features. Genetic abnormalities associated with AML-MRC are often associated with adverse prognostic features, and many cases are preceded by a myelodysplastic syndrom...

journal_title：American journal of clinical pathology

authors： Vardiman J,Reichard K

更新日期：2015-07-01 00:00:00

abstract：:By studying more than 1,200 patients with cutaneous melanoma and long-term follow-up, I examined the relationship between solar elastosis and age at diagnosis of melanoma, key features of melanoma, and the outcome of overall survival in melanoma. I found that melanomas with elastosis were diagnosed significantly later...

journal_title：American journal of clinical pathology

authors： Vollmer RT

更新日期：2007-08-01 00:00:00

abstract：:A case is presented of an anterior mediastinal mass arising in a 64-year-old woman that showed on histologic, immunopathologic, and ultra-structural examination features of a poorly differentiated (insular) thyroid carcinoma. The tumor in this patient most likely arose from ectopically displaced thyroid tissue on the ...

journal_title：American journal of clinical pathology

authors： Dominguez-Malagon H,Guerrero-Medrano J,Suster S

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVES:Mutations in CALR (calreticulin) have been discovered in 50% to 80% of JAK2 (Janus kinase 2) and MPL (myeloproliferative leukemia protein) wild-type patients with Philadelphia-negative myeloproliferative neoplasm (MPNs). We evaluate the performance of a monoclonal antibody for immunohistochemical detection o...

journal_title：American journal of clinical pathology

authors： Nomani L,Bodo J,Zhao X,Durkin L,Loghavi S,Hsi ED

更新日期：2016-10-01 00:00:00

abstract：:Transketolases link the Embden-Meyerhof pathway to the pentose phosphate pathway. An influence of p-Akt on this metabolism was described. This study was performed to compare the expression of transketolase-like 1 (TKTL1) and p-Akt in glioblastoma multiforme (GBM) and other astrocytic gliomas (AGs, grades II and III). ...

journal_title：American journal of clinical pathology

authors： Völker HU,Hagemann C,Coy J,Wittig R,Sommer S,Stojic J,Haubitz I,Vince GH,Kämmerer U,Monoranu CM

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:We aimed to find descriptors to identify chronic lymphocytic leukemia (CLL), Sézary, granular, and villous lymphocytes among normal and abnormal lymphocytes in peripheral blood. METHODS:Image analysis was applied to 768 images from 15 different types of lymphoid cells and monocytes to determine four discrim...

journal_title：American journal of clinical pathology

authors： Puigví L,Merino A,Alférez S,Boldú L,Acevedo A,Rodellar J

更新日期：2019-06-05 00:00:00

abstract：:A case of metastatic ameloblastoma of the maxilla with secondary hypercalcemia in a 54-year-old man is presented. After treatment with surgery, chemotherapy, and radiotherapy, the patient was found to have multiple metastases and severe hypercalcemia associated with high levels of parathormone-like substance in the pe...

journal_title：American journal of clinical pathology

authors： Madiedo G,Choi H,Kleinman JG

更新日期：1981-04-01 00:00:00

abstract：:We present what, to our knowledge, is the first reported case of nephrogenic metaplasia of the ureter. Nephrogenic metaplasia involves the transitional epithelium of the urinary tract and results in the formation of epithelial tubules, which are histologically similar to renal tubules. Special stains demonstrated both...

journal_title：American journal of clinical pathology

authors： Lugo M,Petersen RO,Elfenbein IB,Stein BS,Duker NJ

更新日期：1983-07-01 00:00:00

abstract：:Bull's algorithm has been evaluated by computer simulation studies. Varying amounts of systematic analytic error were simulated in either hemoglobin (Hgb), red blood cell count (RBC), or mean corpuscular volume (MCV) with the resulting red blood cell indices averaged in batches of 20 using Bull's algorithm. The number...

journal_title：American journal of clinical pathology

authors： Cembrowski GS,Westgard JO

更新日期：1985-03-01 00:00:00

abstract：:DRC (dendritic reticulum cell) antigen expression was studied in 38 cases of B-cell lymphomas including follicular lymphoma. The results of this study showed DRC-1 to be expressed in 1/3 of small lymphocytic; 3/3 of mantle zone lymphoma (MZL); 10/10 of follicular, small cleaved; 6/7 of follicular, mixed; 1/2 of follic...

journal_title：American journal of clinical pathology

authors： Mori N,Oka K,Kojima M

更新日期：1988-04-01 00:00:00

abstract：:The authors investigated the humoral and tissue expression of six antigens associated with medullary thyroid cancer (MTC): calcitonin (CT), calcitonin gene-related peptide (CGRP), carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), somatostatin (SRIF), and thyroglobulin (TG). The antigens were studied in th...

journal_title：American journal of clinical pathology

authors： Pacini F,Basolo F,Elisei R,Fugazzola L,Cola A,Pinchera A

更新日期：1991-03-01 00:00:00

abstract：:Wild-type apolipoprotein A-I (apo A-I)-derived amyloid commonly occurs in atherosclerotic plaques. To clarify apo A-I amyloid formation, plasma levels of apo A-I and cholesterol were related to the presence of amyloid in atherosclerotic plaques in 15 patients with peripheral atherosclerosis, subjected to arterial reco...

journal_title：American journal of clinical pathology

authors： Mucchiano GI,Jonasson L,Häggqvist B,Einarsson E,Westermark P

更新日期：2001-02-01 00:00:00

abstract：:Chicken pox, although common, is rarely associated with autoimmune hemolytic anemia. Reported here is the case of an 8-year-old boy who was found to have cold agglutinin disease and severe anemia several days after he contracted chicken pox. The cold agglutinin appeared to be a polyclonal immunoglobulin M antibody wit...

journal_title：American journal of clinical pathology

authors： Friedman HD,Dracker RA

更新日期：1992-01-01 00:00:00

abstract：:Results of a comparison of the diagnostic efficacy of percutaneous needle biopsy of the parietal pleura with that of cytologic examination of pleural fluid sediment obtained concurrently from 166 patients with benign or cancerous pleural disorders are reported. Of 44 patients with confirmatory evidence of cancer invol...

journal_title：American journal of clinical pathology

authors： Frist B,Kahan AV,Koss LG

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVES:To compare next-generation sequencing (NGS) platforms with mutation-specific analysis platforms in a clinical setting, in terms of sensitivity, mutation specificity, costs, capacity, and ease of use. METHODS:We analyzed 25 formalin-fixed, paraffin-embedded lung cancer samples of different size and tumor per...

journal_title：American journal of clinical pathology

authors： Hinrichs JW,van Blokland WT,Moons MJ,Radersma RD,Radersma-van Loon JH,de Voijs CM,Rappel SB,Koudijs MJ,Besselink NJ,Willems SM,de Weger RA

更新日期：2015-04-01 00:00:00

abstract：:The authors have assessed the clinical value of an "accurate" band count as a correlate to infection in 33 patients with a culture proven bacterial infection and a normal total leukocyte count. Thirty hematologically normal outpatients, presumably with no infections, were selected for the control group. Manual 500 cel...

journal_title：American journal of clinical pathology

authors： Ardron MJ,Westengard JC,Dutcher TF

更新日期：1994-11-01 00:00:00

abstract：:An anti-serum against human neuron-specific enolase (NSE), raised in sheep, has been characterized and used for immunocytochemical localization of NSE in paraffin sections of normal tissues and lung cancers. Of the small cell carcinomas (SCC), 69 out of 99 (70%) cases stained with the anti-serum. Maltreated biopsies s...

journal_title：American journal of clinical pathology

authors： Bergh J,Esscher T,Steinholtz L,Nilsson K,Påhlman S

更新日期：1985-07-01 00:00:00

abstract：:A rapid, convenient immunologic assay technic for fibrinogen is reported. Basically a latex agglutination, the assay technic, called kinetic latex agglutinometry, quantitates the increase in light transmission that occurs in a stirred suspension of anti-fibrinogen-coated latex beads after the addition of a plasma or w...

journal_title：American journal of clinical pathology

authors： Babson AL,Opper CA,Crane LJ

更新日期：1982-04-01 00:00:00

abstract：:Although red blood cell (RBC) antigen typing by agglutination is generally useful, several situations exist where this approach is difficult or impossible. For example, following a massive transfusion, a patient's residual RBCs are mixed with transfused normal donor RBCs. In this case, typing by hemagglutination prima...

journal_title：American journal of clinical pathology

authors： Eshleman JR,Shakin-Eshleman SH,Church A,Kant JA,Spitalnik SL

更新日期：1995-03-01 00:00:00

abstract：:A variant hemoglobin fraction may be an incidental finding during HbA(1c) analysis using the G8 Tosoh HPLC analyzer, but it is unclear if the retention times and fraction patterns can reliably predict the findings of a high-performance liquid chromatography (HPLC) β-thalassemia program (Bio Rad Variant II analyzer). W...

journal_title：American journal of clinical pathology

authors： Froom P,Henig C,Zalman L,Barak M

更新日期：2012-09-01 00:00:00

abstract：:The authors describe two patients with clinically and histopathologically documented advanced (tumor) stage mycosis fungoides. In each case the large, pleomorphic neoplastic cells lacked the monoclonal antibody-defined cell surface antigens commonly associated with immature and mature T-cells, i.e., T11, Leu-1, T3, T4...

journal_title：American journal of clinical pathology

authors： Wieczorek R,Suhrland M,Ramsay D,Reed ML,Knowles DM 2nd

更新日期：1986-07-01 00:00:00

abstract：:The use of direct thrombin inhibitors (DTIs) for prophylactic or therapeutic anticoagulation is increasing because of the predictable bioavailability and short half-life of these DTIs. However, in certain situations, indication of the concentration is warranted. We investigated the effects of 3 DTIs (lepirudin, argatr...

journal_title：American journal of clinical pathology

authors： Curvers J,van de Kerkhof D,Stroobants AK,van den Dool EJ,Scharnhorst V

更新日期：2012-10-01 00:00:00

abstract：:Chronic myeloproliferative diseases (MPDs) are not associated with consistent cytogenetic or molecular abnormalities. Demonstration of clonal cell growth by analysis of X-chromosome inactivation (XCI) patterns in females provides a promising tool for diagnosis. However, this technique can be complicated by excessive l...

journal_title：American journal of clinical pathology

authors： Mitterbauer G,Winkler K,Gisslinger H,Geissler K,Lechner K,Mannhalter C

更新日期：1999-07-01 00:00:00

abstract：:We assessed cytologic specimens from 11 mantle cell lymphomas (MCLs) and 32 other B-cell non-Hodgkin lymphomas (NHLs) for 11q13 breakpoints using a 2-color fluorescence in situ hybridization (FISH) assay that uses an 11q13 probe centered on the CCND1 gene and a centromeric chromosome 11 probe (CEP11). The number of nu...

journal_title：American journal of clinical pathology

authors： Katz RL,Caraway NP,Gu J,Jiang F,Pasco-Miller LA,Glassman AB,Luthra R,Hayes KJ,Romaguera JE,Cabanillas FF,Medeiros LJ

更新日期：2000-08-01 00:00:00

abstract：:In normal subjects, mean platelet volume (MPV) has an inverse, nonlinear relation with platelet count, while platelet volume heterogeneity has a direct, nonlinear relation with MPV. Compared with the reference range established for normal subjects, patients with chronic lymphocytic leukemia, atherosclerotic heart dise...

journal_title：American journal of clinical pathology

authors： Bessman JD,Williams LJ,Gilmer PR Jr

更新日期：1982-08-01 00:00:00

abstract：Objectives:The plasma-thrombin method is commonly used to make cell blocks from fine-needle aspiration (FNA) samples but requires centrifugation. We describe a modification to this method that does not require centrifugation for use in resource-limited settings. Methods:Pooled fresh plasma is aliquoted into 2-mL Eppen...

journal_title：American journal of clinical pathology

authors： Aisagbonhi O,Birungi A,Atwine R,Behayo P,Ayebaziwe B,Roberts D,Tambouret R

更新日期：2018-07-03 00:00:00

abstract：:This report describes the clinical evaluation of a novel fluorescent immunoassay (FIA), Sofia Influenza A+B FIA (Quidel, San Diego, CA), for the rapid detection and differentiation of influenza A and B viruses. A total of 2,047 subjects provided nasal swabs and nasopharyngeal swabs or aspirates. The overall sensitivit...

journal_title：American journal of clinical pathology

authors： Lewandrowski K,Tamerius J,Menegus M,Olivo PD,Lollar R,Lee-Lewandrowski E

更新日期：2013-05-01 00:00:00