A murine intraperitoneal infection model reveals that host resistance to Campylobacter jejuni is Nramp1 dependent.

abstract：:Exhaustive information on the Epstein-Barr virus, a member of the herpes family, is described at the International Herpes Management Forum web-site. Cervical cancer associations, AIDS treatment projects, and the Los Alamos National Laboratories provide useful information on papillomavirus infections, as well as hyperl...

journal_title：Microbes and infection

authors： Kotra LP,Ojcius DM

更新日期：2000-10-01 00:00:00

abstract：:Parachlamydia acanthamoebae is an obligate intracellular bacterium naturally infecting free-living amoebae. The role of this bacterium as an agent of pneumonia is suggested by sero-epidemiological studies and molecular surveys. Furthermore, P. acanthamoebae may escape macrophages microbicidal effectors. Recently, we d...

journal_title：Microbes and infection

authors： Pilloux L,Casson N,Sommer K,Klos A,Stehle JC,Pusztaszeri M,Greub G

更新日期：2015-11-01 00:00:00

abstract：:Immune-mediated clearance of virus from the central nervous system (CNS) differs from that of the other organs. Mechanisms of virus control are largely dependent upon the target cell type. Although cytolytic T lymphocytes may mediate clearance of virus from glial cells, non-cytolytic mechanisms mediated by antibody an...

journal_title：Microbes and infection

authors： Binder GK,Griffin DE

更新日期：2003-04-01 00:00:00

abstract：:Several bacterial pathogens interact with their host through protein secretion effectuated by a type VI secretion system (T6SS). Francisella tularensis is a highly pathogenic intracellular bacterium that causes the disease tularemia. Proteins encoded by the Francisella pathogenicity island (FPI), which constitute a ty...

journal_title：Microbes and infection

authors： Ozanic M,Marecic V,Lindgren M,Sjöstedt A,Santic M

更新日期：2016-12-01 00:00:00

abstract：:We investigated the epidemiology of antibiotic resistance and virulence properties among Pseudomonas aeruginosa clinical isolates collected in 1999 from patients hospitalized in the intensive care units of the centre hospitalier d'Orléans, in France. We compared the totality of the strains from mechanically ventilated...

journal_title：Microbes and infection

authors： Di Martino P,Gagnière H,Berry H,Bret L

更新日期：2002-05-01 00:00:00

abstract：:Yersiniabactin (Ybt) is a siderophore-dependent iron uptake system encoded on a pathogenicity island that is widespread among pathogenic bacteria including the Yersiniae. While biosynthesis of the siderophore has been elucidated, the secretion mechanism and a few components of the uptake/utilization pathway are uniden...

journal_title：Microbes and infection

authors： Perry RD,Fetherston JD

更新日期：2011-09-01 00:00:00

abstract：:T cells are thought to play a critical role in cerebral malaria pathogenesis. However, available evidences are restricted to rodent models in which V beta specific T cell expansion has been associated with neurological syndrome suggesting involvement of superantigens or dominant antigens. Using flow cytometry, we stud...

journal_title：Microbes and infection

authors： Loizon S,Boeuf P,Tetteh JK,Goka B,Obeng-Adjei G,Kurtzhals JA,Rogier C,Akanmori BD,Mercereau-Puijalon O,Hviid L,Behr C

更新日期：2007-09-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) mostly owes its success to its ability to evade host immune responses. Understanding viral immune escape mechanisms is a prerequisite to improve future HIV-1 vaccine design. This review focuses on the strategies that HIV-1 has evolved to evade recognition by natural killer (...

journal_title：Microbes and infection

authors： Jost S,Altfeld M

更新日期：2012-09-01 00:00:00

abstract：:Campylobacter jejuni and Campylobacter coli together represent the leading bacterial cause of human enteritis. However, the pathogenesis of this disease is poorly understood. Infection results in the formation of crypt abscesses resulting from the migration of neutrophils across the intestinal epithelium and into the ...

journal_title：Microbes and infection

authors： Murphy H,Cogan T,Humphrey T

更新日期：2011-01-01 00:00:00

abstract：:Cell-mediated immunity to Toxoplasma gondii establishes and maintains a balanced host-pathogen relationship. Recent analyses using spontaneous and genetically engineered mouse mutants have yielded a clearer picture of factors positively and negatively regulating the host immune response and a better understanding of c...

journal_title：Microbes and infection

authors： Yap GS,Shaw MH,Ling Y,Sher A

更新日期：2006-04-01 00:00:00

abstract：:The chemokine receptor CCR6 is expressed on naïve B cells, dendritic cell and T-cell subpopulations and is involved in cell navigation during organogenesis and recruitment in response to inflammatory stimuli. Gene-deficient C57BL/6 CCR6(-/-) mice infected with the protozoan parasite Leishmania (L.) major were able to ...

journal_title：Microbes and infection

authors： Lechner A,Ritter U,Varona R,Marquez G,Bogdan C,Körner H

更新日期：2007-03-01 00:00:00

abstract：:Human immunodeficiency virus-1 (HIV-1) infects cells by membrane fusion that is mediated by the envelope proteins gp120/gp41 and the cellular receptors CD4 and CCR5. During this process, some conserved viral epitopes are temporarily exposed and may induce a neutralizing antibody response when fixed in the fusogenic co...

journal_title：Microbes and infection

authors： Zipeto D,Matucci A,Ripamonti C,Scarlatti G,Rossolillo P,Turci M,Sartoris S,Tridente G,Bertazzoni U

更新日期：2006-05-01 00:00:00

abstract：:We investigated the thymic and peripheral T-lymphocyte subsets in BALB/c mice undergoing acute or chronic Trypanosoma cruzi infection, in terms of expression of particular Vbeta rearrangements of the T-cell receptor. We first confirmed the severe depletion of CD4(+)CD8(+) thymocytes following acute T. cruzi infection....

journal_title：Microbes and infection

authors： Mendes-da-Cruz DA,de Meis J,Cotta-de-Almeida V,Savino W

更新日期：2003-08-01 00:00:00

abstract：:Two strains of mice selected according to extreme phenotypes of susceptibility and resistance to oral tolerance (TS and TR mice, respectively) were infected with 1 x 10(7) Leishmania amazonensis promastigotes and studied comparatively. TS mice developed a minor pathology while permitting parasite growth with the prese...

journal_title：Microbes and infection

authors： Tavares D,da Conceição Ribeiro R,Carlos da Silva A

更新日期：2006-04-01 00:00:00

abstract：:Infectious diseases are major causes, with malignancies, of morbidity and mortality in the elderly. Increased susceptibility to infections may result from underlying dysfunction of an aged immune system; moreover, inappropriate immunologic functions associated with aging can determine an insufficient response to vacci...

journal_title：Microbes and infection

authors： Ginaldi L,Loreto MF,Corsi MP,Modesti M,De Martinis M

更新日期：2001-08-01 00:00:00

abstract：:Purging HIV-1 to cure the infection in patients undergoing suppressive antiretroviral therapy requires targeting all possible viral reservoirs. Other than the memory CD4(+) T cells, several other HIV-1 reservoirs have been identified. HIV-1 infection in the brain as a reservoir is well documented, but not fully charac...

journal_title：Microbes and infection

authors： Chauhan A

更新日期：2015-09-01 00:00:00

abstract：:Clostridium difficile is now established as a major nosocomial pathogen. C. difficile infection is seen almost exclusively as a complication of antibiotic therapy, and is particularly associated with clindamycin and third-generation cephalosporins. Depletion of the indigenous gut microflora by antibiotic therapy has l...

journal_title：Microbes and infection

authors： Freeman J,Wilcox MH

更新日期：1999-04-01 00:00:00

abstract：:In early 2014, a novel subclade (2.3.4.4) of the highly pathogenic avian influenza (HPAI) A(H5N8) virus caused the first outbreak in domestic ducks and migratory birds in South Korea. Since then, it has spread to 44 countries and regions. To date, no human infections with A(H5N8) virus have been reported, but the poss...

journal_title：Microbes and infection

authors： Xu W,Dai Y,Hua C,Wang Q,Zou P,Deng Q,Jiang S,Lu L

更新日期：2017-12-01 00:00:00

abstract：:Effective vaccines against infectious diseases and biological warfare agents remain an urgent public health priority. Studies have characterized the differentiation of effector and memory T cells and identified a subset of T cells capable of conferring enhanced protective immunity against pathogen challenge. We hypoth...

journal_title：Microbes and infection

authors： Brice GT,Dobaño C,Sedegah M,Stefaniak M,Graber NL,Campo JJ,Carucci DJ,Doolan DL

更新日期：2007-10-01 00:00:00

abstract：:Amoebiasis is responsible for 50000-100000 deaths annually. Invasive amoebic disease begins with the attachment of Entamoeba histolytica trophozoites to colonic mucin, a process mediated by the amoebic Gal/GalNAc lectin. The non-pathogenic counterpart, E. dispar, is morphologically identical but genetically distinct. ...

journal_title：Microbes and infection

authors： Pillai DR,Kain KC

更新日期：2000-11-01 00:00:00

abstract：:Paracoccidioides brasiliensis is a dimorphic fungus known to produce invasive systemic disease in humans. The 43-kDa glycoprotein of P. brasiliensis is the major diagnostic antigen of paracoccidioidomycosis and may act as a virulence factor, since it is a receptor for laminin.Very little is known about early interacti...

journal_title：Microbes and infection

authors： Hanna SA,Monteiro da Silva JL,Giannini MJ

更新日期：2000-07-01 00:00:00

abstract：:Tissue Factor (TF) is the initiator of coagulation and Tissue Factor Inhibitor (TFPI) is the physiological inhibitor of the TF/FVIIa complex. Circulating levels of TF and TFPI were quantified in dengue patients and the relationships with disease severity and infecting serotype analysed. A significant decrease in TF an...

journal_title：Microbes and infection

authors： Leal de Azeredo E,Solórzano VE,de Oliveira DB,Marinho CF,de Souza LJ,da Cunha RV,Damasco PV,Kubelka CF,de-Oliveira-Pinto LM

更新日期：2017-01-01 00:00:00

abstract：:In this report, we examined the genetic diversity of HIV-1 strains circulating in the city of Beira, the second largest metropolitan area in Mozambique. A total of 131 blood samples, collected between August and October 2003 from antiretroviral-naïve individuals, were characterized with a combined approach consisting ...

journal_title：Microbes and infection

authors： Parreira R,Piedade J,Domingues A,Lobão D,Santos M,Venenno T,Baptista JL,Mussa SA,Barreto AT,Baptista AJ,Esteves A

更新日期：2006-08-01 00:00:00

abstract：:Filifactor alocis, a previously unrecognized Gram-positive anaerobic rod, is now considered a new emerging pathogen that may play a significant role in periodontal disease. F. alocis' unique characteristics and variations at the molecular level that may be responsible for the functional changes required to mediate the...

journal_title：Microbes and infection

authors： Aruni AW,Mishra A,Dou Y,Chioma O,Hamilton BN,Fletcher HM

更新日期：2015-07-01 00:00:00

abstract：:Anti-retroviral therapy is useful to treat human immunodeficiency virus type 1 (HIV-1)-infected individuals, but has some major problems, such as the generation of multidrug-resistant viruses. To develop a novel supplemental or alternative therapeutic for CCR5-tropic (R5) HIV-1 infection, we generated a recombinant ve...

journal_title：Microbes and infection

authors： Okuma K,Fukagawa K,Kohma T,Takahama Y,Hamaguchi Y,Ito M,Tanaka Y,Buonocore L,Rose JK,Hamaguchi I

更新日期：2017-01-01 00:00:00

abstract：:Comparative genomics and microarrays reveal that the genomes of different Salmonella enterica serovars are distinguished from each other by the presence or absence of hundreds of genes. The distribution of these variable genome regions is often not clonal. Therefore, lateral gene transfer (LGT) plays an important role...

journal_title：Microbes and infection

authors： Porwollik S,McClelland M

更新日期：2003-09-01 00:00:00

abstract：:Innate lymphoid cells (ILCs) are the innate counterpart of T cells. Upon infection or injury, ILCs react promptly to direct the developing immune response to the one most adapted to the threat facing the organism. Therefore, ILCs play an important role early in resistance to infection, but also to maintain homeostasis...

journal_title：Microbes and infection

authors： Cording S,Medvedovic J,Lecuyer E,Aychek T,Eberl G

更新日期：2018-01-01 00:00:00

abstract：:Several pathogens including Gram-negative bacteria hijack complement regulators to escape host's innate response. Pathogenic Leptospira species bind Factor H, C4b binding protein and vitronectin from the complement system. We evaluated the ability of low passage (LP) and culture-attenuated (CA) pathogenic strains of L...

journal_title：Microbes and infection

authors： Moreno-Torres A,Malvido-Jiménez IR,de la Peña-Moctezuma A,Castillo Sánchez LO,Fraga TR,Barbosa AS,Isaac L,Sahagún-Ruiz A

更新日期：2019-01-01 00:00:00

abstract：:Parasites of the Leishmania genus are the causative agents of a complex disease called leishmaniasis. Many activities of infected cells including their responses to a range of stimuli are modulated by Leishmania parasites. This review will profile some of the parasite molecules that target host cell processes for whic...

journal_title：Microbes and infection

authors： Kima PE

更新日期：2014-09-01 00:00:00

abstract：:To increase knowledge of the pathogenic potential of the Burkholderia cepacia complex (BCC), we investigated the effects of reference strains of the nine BCC species on human bronchial epithelial cells in vitro. B. multivorans exhibited the highest rates of adherence to and internalization by host cells. Two out of th...

journal_title：Microbes and infection

authors： Moura JA,Cristina de Assis M,Ventura GC,Saliba AM,Gonzaga L Jr,Si-Tahar M,Marques Ede A,Plotkowski MC

更新日期：2008-01-01 00:00:00