Neighbourhood deprivation and incident mobility disability in older adults.

abstract：:In a study of two representative population samples of 70-year-olds, one of which was followed up at 75 years of age, digitalis treatment was associated with oestrogen-like metabolic effects, indicated by changes in the composition of the plasma phospholipid fraction. Digitalis treatment, at least at these ages, is re...

journal_title：Age and ageing

authors： Persson G,Landahl S,Svanborg A

更新日期：1982-11-01 00:00:00

abstract：:In this study we examine whether the introduction of a clerking pro forma improves the completeness of the recording of the management of stroke patients and we review methodological issues important in this type of audit. We prospectively identified 244 consecutive stroke patients before and after the introduction of...

journal_title：Age and ageing

authors： Davenport RJ,Dennis MS,Warlow CP

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:age-related hearing loss is a common chronic condition; hence, it is important to understand its influence on the functional status of older adults. We assessed the association between hearing impairment with activity limitations as assessed by the activities of daily living (ADL) scale. METHODS:a total of ...

journal_title：Age and ageing

authors： Gopinath B,Schneider J,McMahon CM,Teber E,Leeder SR,Mitchell P

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:delirium is a frequent complication of hospital admission for older people and can be reduced by multicomponent interventions, but implementation and delivery of such interventions is challenging. OBJECTIVE:to investigate fidelity to the prevention of delirium system of care within a multicentre, pragmatic,...

journal_title：Age and ageing

authors： Smith J,Green J,Siddiqi N,Inouye SK,Collinson M,Farrin A,Young J

更新日期：2020-07-01 00:00:00

abstract：:Falls pose a major threat to the well-being and quality of life of older people. Falls can result in fractures and other injuries, disability and fear and can trigger a decline in physical function and loss of autonomy. This article synthesises recent published findings on fall risk and mobility assessments and fall p...

journal_title：Age and ageing

authors： Lord SR,Close JCT

更新日期：2018-07-01 00:00:00

abstract：:The results reported here are from a 2-year follow-up study of 58 elderly patients in a continuing-care unit. Most of these patients were in a hyperosmolar state at the time of entry (mean plasma osmolality 304 +/- 8 mOsmol/kg). The survival of those patients with the highest osmolality (greater than 308 mOsmol/kg) wa...

journal_title：Age and ageing

authors： O'Neill PA,Faragher EB,Davies I,Wears R,McLean KA,Fairweather DS

更新日期：1990-01-01 00:00:00

abstract：:There have so far been no reported studies of localization of urinary tract infection (UTI) in elderly women. The site of infection, renal or bladder, in significant urinary tract infection in 50 elderly women (mean age 80) admitted acutely to a geriatric unit was determined by the Fairley bladder washout method. Of t...

journal_title：Age and ageing

authors： Suntharalingam M,Seth V,Moore-Smith B

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:to investigate auditory function in subjects with early Alzheimer's disease, mild cognitive impairment and with subjective memory complaints, in search of signs of central auditory processing dysfunction even in early stages of cognitive impairment. DESIGN AND SUBJECTS:a consecutive group of men and women, r...

journal_title：Age and ageing

authors： Idrizbegovic E,Hederstierna C,Dahlquist M,Kämpfe Nordström C,Jelic V,Rosenhall U

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The risk/benefit ratio of warfarin therapy changes in the over 75s, when haemorrhagic side-effects become more common. These may not always be reported in the literature. CASE REPORT:A woman of 80 years, on long-term warfarin therapy presented with an acute dissecting thoracic aortic aneurysm; on investigat...

journal_title：Age and ageing

authors： Blunt DM,Impallomeni MG

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:the relationship between proximity to death and the amount of care provided by general practitioners (GPs) is largely unknown. OBJECTIVE:to examine the influence of the proximity to death on the frequency and length of GP contacts in the oldest old. STUDY DESIGN:this population-based follow-up study includ...

journal_title：Age and ageing

authors： Blom JW,Lemmens SP,Assendelft WJ,Eekhof JA,Gussekloo J

更新日期：2012-11-01 00:00:00

abstract：Background:high cardiorespiratory fitness (CRF) is associated with larger brain volumes but data on sex differences in the association of CRF with brain volumes are scarce. We investigated whether the association of CRF with total grey matter (GM) and white matter volumes as well as medial temporal lobe and striatum vo...

journal_title：Age and ageing

authors： Pentikäinen H,Ngandu T,Liu Y,Savonen K,Komulainen P,Hallikainen M,Kivipelto M,Rauramaa R,Soininen H

更新日期：2017-03-01 00:00:00

abstract：:A sample of 761 subjects 70 years and over was drawn from general-practice records of a rural township. Each subject was assessed and followed for 1 year to determine the incidence of and factors related to falls. The fall rate (number of falls per 100 person-years) increased from 47 for those aged 70-74 years to 121 ...

journal_title：Age and ageing

authors： Campbell AJ,Borrie MJ,Spears GF,Jackson SL,Brown JS,Fitzgerald JL

更新日期：1990-03-01 00:00:00

abstract：:Hospital-at-Home schemes have been claimed to hasten the discharge of elderly orthopaedic patients, and are becoming increasingly popular with health service managers. In an attempt to measure the benefits of such a scheme when applied to elderly medical patients, we prospectively randomized 60 consecutive referrals o...

journal_title：Age and ageing

authors： Donald IP,Baldwin RN,Bannerjee M

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVES:the impact of retirement on physical health is an important focus of ageing research; however, research findings vary greatly. To investigate under what conditions retirement might benefit health, we examined physical functioning 8 years pre- and post-retirement. METHODS:using longitudinal data from the New...

journal_title：Age and ageing

authors： Szabó Á,Allen J,Stephens C,Alpass F

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:the incidence of pulmonary embolism increases with age but the 'classical' presentation of acute pulmonary embolism may not occur in older persons. OBJECTIVES:to compare the clinical presentation of younger and older patients with acute pulmonary embolism. DESIGN:retrospective identification of 60 consecut...

journal_title：Age and ageing

authors： Timmons S,Kingston M,Hussain M,Kelly H,Liston R

更新日期：2003-11-01 00:00:00

abstract：:Formal assessment of cognitive decline with cognitive tests can be difficult, requiring either two measurement points or a comparison of 'hold' with 'don't hold' tests. Informant-based assessment provides an alternative approach because informants can adopt a longitudinal perspective and directly rate cognitive change...

journal_title：Age and ageing

authors： Jorm AF,Christensen H,Henderson AS,Jacomb PA,Korten AE,Mackinnon A

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:STOPP/START was formulated to identify potentially inappropriate prescribing (PIP) and potential prescribing omissions (PPOs) in older people. The purpose of this study was to determine the prevalence of PIP and PPO in older Irish patients in residential care using STOPP/START. METHODS:data were collected p...

journal_title：Age and ageing

authors： Ryan C,O'Mahony D,Kennedy J,Weedle P,Cottrell E,Heffernan M,O'Mahony B,Byrne S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:older people aged 80 and over are increasingly providing end-of-life care to spouses at home and often do so for long periods of time, while also trying to manage their own illnesses and disabilities. Little of the research on older spousal carers has focussed on the oldest carers; hence, the needs of this p...

journal_title：Age and ageing

authors： Turner M,King C,Milligan C,Thomas C,Brearley SG,Seamark D,Wang X,Blake S,Payne S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:self-rated health (SRH) likely reflects both mental and physical health domains, and is assessed by asking individuals to describe their health status. Poor SRH is associated with disease incidence and subsequent mortality. Changes in SRH across time in persons with different incident diseases are uncharacte...

journal_title：Age and ageing

authors： Foraker RE,Rose KM,Chang PP,McNeill AM,Suchindran CM,Selvin E,Rosamond WD

更新日期：2011-11-01 00:00:00

abstract：:A simple random sample of older people composed of 215 men and 272 women aged 62 years and over was examined in Edinburgh in 1968-9. After one year, 86 per cent of the men and 79 per cent of the women were re-examined; 7 per cent of the men and 4 per cent of the women had died and the remainder were not re-examined fo...

journal_title：Age and ageing

authors： Milne JS,Chopin JM

更新日期：1975-08-01 00:00:00

abstract：OBJECTIVES:To examine whether in older people perceived age is associated with risk of total mortality independent of chronological age. DESIGN:Prospective population-based study (Evergreen project) with mortality surveillance for 13 years after the baseline. SETTING:Face-to-face interview among community-dwelling re...

journal_title：Age and ageing

authors： Uotinen V,Rantanen T,Suutama T

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:the absolute number of notifications for tuberculosis in older people appears to have increased in Scotland. To determine if these trends are present elsewhere in the UK, we have reviewed notifications in Leeds with particular reference to non-pulmonary disease, Asian subcontinent groups and older people. M...

journal_title：Age and ageing

authors： Phelan F,Teale C

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:exposures in childhood and adolescence may impact the development of diseases and symptoms in late life. However, evidence from low- and middle-income countries is scarce. In this cross-sectional study, we examined the association of early life risk factors with frailty amongst older adults using a large, na...

journal_title：Age and ageing

authors： Li Y,Xue QL,Odden MC,Chen X,Wu C

更新日期：2020-02-27 00:00:00

abstract：:Older people attend accident and emergency departments more frequently than younger people. However, most assessments indicate that this higher level of use is appropriate and is the result of more serious injury and illness among this population. Older patients discharged from accident and emergency departments are f...

journal_title：Age and ageing

authors： Burns E

更新日期：2001-08-01 00:00:00

abstract：:Seventy-nine patients with probable Alzheimer's disease were enrolled into a double-blind, placebo-controlled cross-over study to assess the therapeutic effect and safety of THA (tetrahydroaminoacridine; tacrine) without concomitant lecithin administration. Forty-one patients completed the trial which consisted of two...

journal_title：Age and ageing

authors： Wilcock GK,Surmon DJ,Scott M,Boyle M,Mulligan K,Neubauer KA,O'Neill D,Royston VH

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:avoidance of over anticoagulation in response to warfarin therapy would reduce risk of associated bleeding. SUBJECTS:two elderly patients with venous thromboembolism exhibited extreme anticoagulant response to warfarin. Both were noted to have variant CYP2C9 alleles, which reduce the metabolic capacity of c...

journal_title：Age and ageing

authors： Khan T,Kamali F,Daly A,King B,Wynne HA

更新日期：2003-03-01 00:00:00

abstract：:Delirium is a common presentation in older inpatients with COVID-19, and a risk factor for cognitive decline at discharge. The glaring gaps in the service provision in delirium care, regardless of aetiology, after a hospital admission pre-existed the pandemic, but the pandemic arguably offers an opportunity now to add...

journal_title：Age and ageing

authors： Rahman S,Byatt K

更新日期：2021-01-22 00:00:00

abstract：:In one experiment, four groups of six-week-old-male PVG rats were, respectively, given tap water ('control group'), 0.00125M, 0.0025M, and 0.005M lathyrogen (aminoacetonitrile hydrochloride: AAN) solutions ad libitum for a period of 20 weeks. In a second experiment, 12-week-old male rats were similarly treated. It was...

journal_title：Age and ageing

authors： Morgan AJ,Bellamy D

更新日期：1976-08-01 00:00:00

abstract：INTRODUCTION:ageing is accompanied by impairments in immune responses due to remodelling of the immune system (immunesenescence). Additionally, a decline in habitual physical activity has been reported in older adults. We have recently published that specific features of immunesenescence, such as thymic involution and ...

journal_title：Age and ageing

authors： Bartlett DB,Duggal NA

更新日期：2020-04-27 00:00:00

abstract：INTRODUCTION:care home residents have high healthcare needs not fully met by prevailing healthcare models. This study explored how healthcare configuration influences resource use. METHODS:a realist evaluation using qualitative and quantitative data from case studies of three UK health and social care economies select...

journal_title：Age and ageing

authors： Gordon AL,Goodman C,Davies SL,Dening T,Gage H,Meyer J,Schneider J,Bell B,Jordan J,Martin FC,Iliffe S,Bowman C,Gladman JRF,Victor C,Mayrhofer A,Handley M,Zubair M

更新日期：2018-07-01 00:00:00