Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of IL15.

abstract：BACKGROUND:polypharmacy is an important risk factor for falls, but recent studies suggest only when including medications associated with increasing the risk of falls. DESIGN:a prospective, population-based cohort study. SUBJECTS:6,666 adults aged ≥50 years from The Irish Longitudinal study on Ageing. METHODS:partic...

journal_title：Age and ageing

authors： Richardson K,Bennett K,Kenny RA

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:to determine the prevalence of vertebral fractures and their risk factors in geriatric patients. DESIGN:prospective cohort study. SETTING:teaching hospital in Amsterdam, The Netherlands. SUBJECTS:three hundred and three geriatric patients, who had their first visit at a diagnostic day hospital between Apr...

journal_title：Age and ageing

authors： van der Jagt-Willems HC,van Hengel M,Vis M,van Munster BC,van Campen JP,Tulner LR,Lems WF

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:In older ambulatory persons, exercise strategies that are expected to generate beneficial muscle adaptations with low cardiopulmonary demands are needed. OBJECTIVE:We hypothesised that eccentric resistance exercise would be less demanding on the cardiovascular and pulmonary systems than bouts of concentric ...

journal_title：Age and ageing

authors： Vallejo AF,Schroeder ET,Zheng L,Jensky NE,Sattler FR

更新日期：2006-05-01 00:00:00

abstract：:At present, frailty is defined variably. Some consensus on a definition is likely to emerge, but the basis for a successful definition needs to be explored. Here, a classic approach to validation is proposed: a successful definition of frailty should be multifactorial but must also manage the many factors in a way tha...

journal_title：Age and ageing

authors： Rockwood K

更新日期：2005-09-01 00:00:00

abstract：:Alcohol consumption constitutes a substantial burden of disease. Older people are being admitted to hospital for alcohol problems in increasing numbers. A recent systematic review reports cautious supportive evidence for primary prevention interventions in reducing excessive alcohol consumption in older drinkers, but ...

journal_title：Age and ageing

authors： Crome IB,Crome P

更新日期：2018-03-01 00:00:00

abstract：Background:measuring the complex needs of care home residents is crucial for resource allocation. Hospital patient administration systems (PAS) may not accurately identify admissions from care homes. Objective:to develop and validate an accurate, practical method of identifying care home resident hospital admission us...

journal_title：Age and ageing

authors： Housley G,Lewis S,Usman A,Gordon AL,Shaw DE

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:vascular disease has been postulated to contribute to muscle dysfunction in old age. Previous studies examining the effects of cardiovascular drugs on muscle function have shown conflicting results. We therefore examined the association of angiotensin converting enzyme (ACE) inhibitor, thiazide and statin us...

journal_title：Age and ageing

authors： Witham MD,Syddall HE,Dennison E,Cooper C,McMurdo ME,Sayer AA

更新日期：2014-09-01 00:00:00

abstract：:Data on National Health Service (NHS) dental care utilization by the elderly are analysed to consider the distribution of dental care according to the charge status of the patient. Considerable and significant differences are observed in the type and amount of dental care provided to elderly patients exempt and not ex...

journal_title：Age and ageing

authors： Birch S

更新日期：1989-03-01 00:00:00

abstract：IMPORTANCE:risk factors for delirium in hospital inpatients are well established, but less is known about whether delirium occurring in the community or during an emergency admission to hospital care might be predicted from routine primary-care records. OBJECTIVES:identify risk factors in primary-care electronic healt...

journal_title：Age and ageing

authors： Bowman K,Jones L,Masoli J,Mujica-Mota R,Strain D,Butchart J,Valderas JM,Fortinsky RH,Melzer D,Delgado J

更新日期：2020-04-27 00:00:00

abstract：Background:orthostatic hypotension (OH) is a common disabling condition associated with increased morbidity and mortality. Much of the evidence available is derived from younger populations with chronic neurological disease leading to uncertainty for the diagnosis and management of older people. Objective:to provide a...

journal_title：Age and ageing

authors： Frith J,Parry SW

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Obtaining well-founded estimates of the effect of demographic change on future health expenditures is a pressing issue in all developed countries. Thus far, expenditure projections have examined the effect of age on health care costs, but fail to account for the influence of remaining life expectancy on cost...

journal_title：Age and ageing

authors： Seshamani M,Gray A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:dysphagia is common in acute stroke. Accurate detection of the presence or absence of aspiration by bedside swallowing assessment is difficult without objective methods, tending to over-diagnose aspiration. As a result, some patients suffer restricted oral intake unnecessarily. OBJECTIVE:we examined the pre...

journal_title：Age and ageing

authors： Smith HA,Lee SH,O'Neill PA,Connolly MJ

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVES:To compare costs and outcome of occupational therapy-led assessment with social worker-led assessment of older people, in terms of their independence and quality of life. DESIGN:Cost-effectiveness analysis alongside a randomised controlled trial. The analysis took viewpoints of health services and patients....

journal_title：Age and ageing

authors： Flood C,Mugford M,Stewart S,Harvey I,Poland F,Lloyd-Smith W

更新日期：2005-01-01 00:00:00

abstract：:Vaginal pessaries are widely considered to be a safe alternative to surgery in older women. We report a case of near fatal septicaemia in a 75-year-old woman associated with a shelf pessary, the presence of which was identified during an exploratory laparotomy. This case highlights the importance of the gynaecological...

journal_title：Age and ageing

authors： Wheeler LD,Lazarus R,Torkington J,O'Mahony MS,Woodhouse KW

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The long-term effectiveness of group continence promotion delivered via community organisations on female urinary incontinence, falls and healthy life expectancy remains unknown. METHODS:A pragmatic cluster randomised trial was conducted among 909 women aged 65-98 years with urinary incontinence, recruited ...

journal_title：Age and ageing

authors： Tannenbaum C,Fritel X,Halme A,van den Heuvel E,Jutai J,Wagg A

更新日期：2019-07-01 00:00:00

abstract：:Twenty digitalized elderly patients with chronic atrial fibrillation were randomized into a double-blind cross-over study. None was in overt heart failure and all were taking < 80 mg frusemide daily. They received xamoterol 200 mg b.d. for 2 months with their usual dose of digoxin for 1 month and placebo digoxin for t...

journal_title：Age and ageing

authors： Lawson-Matthew PJ,McLean KA,Dent M,Austin CA,Channer KS

更新日期：1995-07-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs are currently being investigated as agents to reduce the incidence and progression of Alzheimer's disease. Paradoxically they have also been reported to induce deleterious effects on the central nervous system, including aseptic meningitis and cognitive decline in the elderly. We ...

journal_title：Age and ageing

authors： Ashton D,Kim P,Griffiths N,Beran R

更新日期：2004-07-01 00:00:00

abstract：:Lyme disease is an infectious disease caused by the Borrelia burgdorferi spirochetes and other related species that are transmitted through an infected tick bite. We report the case of an older patient presenting with bilateral facial palsy due to Lyme disease. Multiple non-specific clinical signs preceded facial pals...

journal_title：Age and ageing

authors： Méreaux JL,Hébant B,Magne N,Quesney G,Lefaucheur R

更新日期：2020-08-24 00:00:00

abstract：:Sway has been measured by Wright's Ataxiameter in 151 frail elderly and five young subjects, and compared with various sensory modalities. There is a close relationship between increased sway and impaired vibration sense in the legs. No correlations emerged with proprioception but this may reflect the imprecision of t...

journal_title：Age and ageing

authors： Brocklehurst JC,Robertson D,James-Groom P

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:Dementia is a predictor of death and institutionalization. It is less clear if variations in cognition within the normal range predict adverse outcomes. OBJECTIVE:To determine if variation at the high end of cognitive test scores predicts mortality or institutionalization, independent of the effect of poten...

journal_title：Age and ageing

authors： St John PD,Montgomery PR,Kristjansson B,McDowell I

更新日期：2002-09-01 00:00:00

abstract：:Tests of intestinal permeability are used as a reflection of upper-small-intestinal mucosal damage. Thirty-two elderly in-patients aged 75-96 years, and 64 hospital volunteers aged 22-64 years with no overt gastro-intestinal disease were studied to determine whether permeability changes with increasing age. Intestinal...

journal_title：Age and ageing

authors： Saweirs WM,Andrews DJ,Low-Beer TS

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:To determine the presentation, course and duration of delirium in hospitalized older people. DESIGN:Observational cohort study. SETTING:Inpatient surgical and medical wards at a university hospital. PARTICIPANTS:432 people over the age of 65. MEASUREMENTS:All participants were screened daily for confusio...

journal_title：Age and ageing

authors： Rudberg MA,Pompei P,Foreman MD,Ross RE,Cassel CK

更新日期：1997-05-01 00:00:00

abstract：:The contribution of the elderly to the workload of a combined consultative District Hospital Gastroenterology Clinic has been studied over a 12-year period. The elderly group comprise 24% of the total referrals with a gradually increasing trend over successive years. The service implications are discussed and the main...

journal_title：Age and ageing

authors： Purkayastha SK,Salter RH,Holmes KM

更新日期：1988-01-01 00:00:00

abstract：:Congestive heart failure (CHF) is the most common discharge diagnosis for elderly patients. The survival of elderly (age greater than or equal to 75 years) patients with CHF has not recently been reported, especially with reference to left ventricular ejection fraction (LVEF). A patient database was searched for the d...

journal_title：Age and ageing

authors： Taffet GE,Teasdale TA,Bleyer AJ,Kutka NJ,Luchi RJ

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:to explore views on advance care planning in care homes for older people. DESIGN:qualitative exploration of views from care home staff and the family of residents in care homes for older people. SETTING:all care homes for the elderly in two London Boroughs. PARTICIPANTS:staff (care managers, nurses and car...

journal_title：Age and ageing

authors： Stewart F,Goddard C,Schiff R,Hall S

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:exposures in childhood and adolescence may impact the development of diseases and symptoms in late life. However, evidence from low- and middle-income countries is scarce. In this cross-sectional study, we examined the association of early life risk factors with frailty amongst older adults using a large, na...

journal_title：Age and ageing

authors： Li Y,Xue QL,Odden MC,Chen X,Wu C

更新日期：2020-02-27 00:00:00

abstract：:Mild cognitive impairment (MCI) is a common clinical syndrome that identifies people at high risk of developing dementia. Although treatments for MCI are currently unavailable, preliminary evidence has identified potential neuro-protective effects of physical activity, which may lead to improved outcomes. However, the...

journal_title：Age and ageing

authors： Barber SE,Clegg AP,Young JB

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:to develop a model to predict one- and three-year mortality in patients with dementia attending a hospital, through hospital admission or day/memory clinic. DESIGN:we constructed a cohort of dementia patients through data linkage of three Dutch national registers: the hospital discharge register (HDR), the p...

journal_title：Age and ageing

authors： van de Vorst IE,Golüke NMS,Vaartjes I,Bots ML,Koek HL

更新日期：2020-04-27 00:00:00

abstract：Background:overactive bladder (OAB) is a common condition in older persons. Antimuscarinic treatment remains the mainstay of treatment of OAB but clinicians have been reluctant to prescribe this to older patients. This study examined efficacy and safety information from patients >65 in fesoterodine trials to reaffirm e...

journal_title：Age and ageing

authors： Wagg A,Arumi D,Herschorn S,Angulo Cuesta J,Haab F,Ntanios F,Carlsson M,Oelke M

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:the empirical Dignity Model has profoundly influenced the provision of palliative care for older terminally ill patients in the West, as it provides practical guidance and intervention strategies for promoting dignity and reducing distress at the end-of-life. OBJECTIVE:to examine the concept of 'living and ...

journal_title：Age and ageing

authors： Ho AH,Chan CL,Leung PP,Chochinov HM,Neimeyer RA,Pang SM,Tse DM

更新日期：2013-07-01 00:00:00