What would make a definition of frailty successful?

abstract：OBJECTIVES:To evaluate the influence of age on the day-night blood pressure rhythm and on the prevalence of vascular events in those whose systolic blood pressure (SBP) fell by <10% overnight (non-dippers). DESIGN:Cross-sectional observational cohort study. SETTING:Outpatient hypertension clinic. PARTICIPANTS:419 Hy...

journal_title：Age and ageing

authors： Di Iorio A,Marini E,Lupinetti M,Zito M,Abate G

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:age-related hearing loss is a common chronic condition; hence, it is important to understand its influence on the functional status of older adults. We assessed the association between hearing impairment with activity limitations as assessed by the activities of daily living (ADL) scale. METHODS:a total of ...

journal_title：Age and ageing

authors： Gopinath B,Schneider J,McMahon CM,Teber E,Leeder SR,Mitchell P

更新日期：2012-03-01 00:00:00

abstract：Background:pain is prevalent in frail older adults; however, the association of pain and frailty has not been evaluated yet by a systematic assessment of prospective longitudinal studies. Objective:we aimed to assess the association of persistent pain as a risk factor for frailty incidence, using data from longitudina...

journal_title：Age and ageing

authors： Saraiva MD,Suzuki GS,Lin SM,de Andrade DC,Jacob-Filho W,Suemoto CK

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Care management and assessment of need are the cornerstones of the community care reforms in the UK. Although much of the research base has been on highly vulnerable older people, in practice, care management has been implemented for a wider group. OBJECTIVE:To examine how intensive care-management at home ...

journal_title：Age and ageing

authors： Challis D,Darton R,Hughes J,Stewart K,Weiner K

更新日期：2001-09-01 00:00:00

abstract：:In a study of two representative population samples of 70-year-olds, one of which was followed up at 75 years of age, digitalis treatment was associated with oestrogen-like metabolic effects, indicated by changes in the composition of the plasma phospholipid fraction. Digitalis treatment, at least at these ages, is re...

journal_title：Age and ageing

authors： Persson G,Landahl S,Svanborg A

更新日期：1982-11-01 00:00:00

abstract：:Many studies have shown the indigenous elderly population and Asian immigrants to be groups at particular risk of vitamin D deficiency and osteomalacia, but there are no data on the risks in elderly Asians. In this community-based study a group of elderly Asians was compared with control groups of elderly and young wh...

journal_title：Age and ageing

authors： Solanki T,Hyatt RH,Kemm JR,Hughes EA,Cowan RA

更新日期：1995-03-01 00:00:00

abstract：:Previous work has shown persistent elevations in plasma cortisol concentration following upper femur fracture in elderly people. To investigate this phenomenon further, we measured plasma cortisol and adrenocorticotrophin (ACTH) and performed overnight dexamethasone suppression tests in carefully characterized patient...

journal_title：Age and ageing

authors： Roberts NA,Barton RN,Horan MA,White A

更新日期：1990-09-01 00:00:00

abstract：:Doppler-shifted ultrasound and spectral analysis were used to assess signals from the resting supra-orbital artery and the common carotid artery at the base of the neck of 658 (270 male, 388 female) asymptomatic subjects aged 5 to 90 years. The sonagrams obtained showed two peaks (A and B) during cardiac systole. The ...

journal_title：Age and ageing

authors： Baskett JJ,Lewis RR,Beasley MG,Gosling RG

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:we aimed to investigate the association of smoking cessation with risk of all-cause mortality amongst oldest old people (aged ≥ 80 years). DESIGN:this was a prospective cohort study. SETTING:the Chinese Longitudinal Healthy Longevity Survey, implemented in 23 provinces of China. PARTICIPANTS:a total of 28,...

journal_title：Age and ageing

authors： Wei Y,Lv Y,Zhou J,Gao X,Duan J,Zhao C,Yin Z,Kang Q,Wu B,Chen C,Mao C,Li J,Shi X

更新日期：2021-01-23 00:00:00

abstract：PURPOSE:Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. METHODS:We reviewed the 2008 STOPP/START criteria to add new evidence-based...

journal_title：Age and ageing

authors： O'Mahony D,O'Sullivan D,Byrne S,O'Connor MN,Ryan C,Gallagher P

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:frequent emergency department (ED) attendance at the end of life disrupts care continuity and contradicts most patients' preference for home-based care. OBJECTIVE:to examine factors associated with frequent (≥3) end of life ED attendances among older people to identify opportunities to improve care. METHOD...

journal_title：Age and ageing

authors： Bone AE,Evans CJ,Henson LA,Gao W,Higginson IJ,BUILDCARE study.

更新日期：2019-09-01 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) is a tremendous therapeutic advance for patients with severe aortic stenosis and high-surgical risk. Since TAVI-treated patients are elderly with multiple co-existing conditions, limited life expectancy and disproportionate health-care expenditures, the aspect of the heal...

journal_title：Age and ageing

authors： Georgiadou P,Sbarouni E,Karavolias GK,Voudris V

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Age is thought to be strongly associated with intensive care outcomes, but this relationship may be confounded by many clinical variables. OBJECTIVES:To compare clinical characteristics of elderly patients (> or = 65 years) admitted to the intensive care unit (ICU) with those in younger patients and to iden...

journal_title：Age and ageing

authors： Vosylius S,Sipylaite J,Ivaskevicius J

更新日期：2005-03-01 00:00:00

abstract：:The world is ageing rapidly. Between 2000 and 2050, the number of people aged ≥65 will double as a proportion of the global population, from 7% to 16%, respectively. By 2050, for the first time in human history, there will be more older people than children (aged 0–14 years) in the population. More distinctive is the ...

journal_title：Age and ageing

authors： van der Cammen TJ,Albayrak A,Voûte E,Molenbroek JF

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:there are around 100,000 new stroke cases and over a million people living with its consequences annually in the UK. This has large impacts on health and social care, unpaid carers and lost productivity. We aimed to estimate associated costs. METHODS:we estimated 2014/2015 annual mean cost per person and ag...

journal_title：Age and ageing

authors： Patel A,Berdunov V,Quayyum Z,King D,Knapp M,Wittenberg R

更新日期：2020-02-27 00:00:00

abstract：:The effect of tamoxifen on the vaginal mucosa and on serum oestrone, oestradiol and gonadotrophin concentrations was investigated in a group of nine postmenopausal women with non-metastatic breast cancer. Compared with fit age-matched controls, the vaginal pH in the tamoxifen-treated group was significantly lower and ...

journal_title：Age and ageing

authors： Miodrag A,Ekelund P,Burton R,Castleden CM

更新日期：1991-01-01 00:00:00

abstract：Background:diabetes increases the risk of frailty that is a leading cause of disability and premature mortality in older people. Metabolic syndrome (MS) and insulin resistance (IR) are strong risk factors for diabetes and could, thus, lead to frailty. However, the association between MS or IR and frailty has barely bee...

journal_title：Age and ageing

authors： Pérez-Tasigchana RF,León-Muñoz LM,Lopez-Garcia E,Gutierrez-Fisac JL,Laclaustra M,Rodríguez-Artalejo F,Guallar-Castillón P

更新日期：2017-09-01 00:00:00

abstract：:We present two cases of acute hepatotoxicity associated with elevated paracetamol (acetaminophen) levels in older patients. Both patients were receiving a standard European dose of oral paracetamol (2 × 500 mg QDS) with no risk factors for slowed metabolism (weight <50 kg, interacting medications, hepatic enzyme induc...

journal_title：Age and ageing

authors： Ging P,Mikulich O,O'Reilly KM

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:health-related quality of life (HRQOL) is an important psycho-social characteristic which may impact an individual's ability to manage their chronic disease. We examined the association between HRQOL and antihypertensive medication adherence in older adults. METHODS:participants were part of a cohort study of ...

journal_title：Age and ageing

authors： Holt EW,Muntner P,Joyce CJ,Webber L,Krousel-Wood MA

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:a fall occurs when an individual experiences a loss of balance from which they are unable to recover. Assessment of balance recovery ability in older adults may therefore help to identify individuals at risk of falls. The purpose of this 12-month prospective study was to assess whether the ability to recover...

journal_title：Age and ageing

authors： Carty CP,Cronin NJ,Nicholson D,Lichtwark GA,Mills PM,Kerr G,Cresswell AG,Barrett RS

更新日期：2015-01-01 00:00:00

abstract：:In the population study Seventy-year-old People in Göteborg, 449 70-year-old men were examined in 1971/72. Out of these, 331 were re-examined in 1976/77 at age 75, together with a cohort-comparison group of 474 70-year-old men. Cohort differences and a lower smoking prevalence at higher ages were observed. The loss of...

journal_title：Age and ageing

authors： Mellström D,Rundgren A,Jagenburg R,Steen B,Svanborg A

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:essential aspects of independence in community mobility among older people concern the control over where, when and how to participate (perceived autonomy), and actual mobility (life-space mobility; frequency, distance and need of assistance). We studied relationships between frailty and life-space mobility ...

journal_title：Age and ageing

authors： Portegijs E,Rantakokko M,Viljanen A,Sipilä S,Rantanen T

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:to develop a model to predict one- and three-year mortality in patients with dementia attending a hospital, through hospital admission or day/memory clinic. DESIGN:we constructed a cohort of dementia patients through data linkage of three Dutch national registers: the hospital discharge register (HDR), the p...

journal_title：Age and ageing

authors： van de Vorst IE,Golüke NMS,Vaartjes I,Bots ML,Koek HL

更新日期：2020-04-27 00:00:00

abstract：:Sway has been measured by Wright's Ataxiameter in 151 frail elderly and five young subjects, and compared with various sensory modalities. There is a close relationship between increased sway and impaired vibration sense in the legs. No correlations emerged with proprioception but this may reflect the imprecision of t...

journal_title：Age and ageing

authors： Brocklehurst JC,Robertson D,James-Groom P

更新日期：1982-02-01 00:00:00

abstract：:Fasting serum cholesterol and triglyceride levels, and lipoprotein electrophoretic patterns have been investigated in 42 men aged 67-92 years (mean 79 years). Although all the cholesterol and the majority of the triglyceride levels were within the normal range for younger people, both were significantly greater (P < 0...

journal_title：Age and ageing

authors： Horsey J,Livesley B,Dickerson JW

更新日期：1980-08-01 00:00:00

abstract：:The effects of discontinuing long-term diuretic therapy were investigated by means of a double-blind randomized controlled trial. A total of 141 elderly patients in the long-stay wards of six hospitals were found to be taking maintenance diuretics, and for 33 of these the drugs were judged to be mandatory. Of the rema...

journal_title：Age and ageing

authors： Burr ML,King S,Davies HE,Pathy MS

更新日期：1977-02-01 00:00:00

abstract：:Prolonged head-up tilt is increasingly used as a diagnostic test for vasovagal syncope. Its sensitivity is reported to increase with the concurrent administration of intravenous isoprenaline. False-positive responses are common in young controls particularly following intravascular instrumentation. We studied the infl...

journal_title：Age and ageing

authors： McIntosh SJ,Lawson J,Kenny RA

更新日期：1994-07-01 00:00:00

abstract：:A cross-sectional survey of community-dwelling elderly volunteers (104 women, 87 men, mean age 70 years) was carried out in winter to determine whether cardiovascular and other potentially modifiable lifestyle factors were associated with serum levels of 25-hydroxyvitamin D during this period. Mean winter levels of se...

journal_title：Age and ageing

authors： Scragg R,Khaw KT,Murphy S

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:there is a suggestion that while the age-adjusted incidence of hip fracture in the West may be declining, the incidence may be rising in Asia. OBJECTIVE:this study examines the incidence and post-fracture mortality from 2001 to 2009 among the population aged 65 years and over. METHODS:hip fracture incidenc...

journal_title：Age and ageing

authors： Chau PH,Wong M,Lee A,Ling M,Woo J

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The risk/benefit ratio of warfarin therapy changes in the over 75s, when haemorrhagic side-effects become more common. These may not always be reported in the literature. CASE REPORT:A woman of 80 years, on long-term warfarin therapy presented with an acute dissecting thoracic aortic aneurysm; on investigat...

journal_title：Age and ageing

authors： Blunt DM,Impallomeni MG

更新日期：2004-03-01 00:00:00