Abstract:
:The effects of discontinuing long-term diuretic therapy were investigated by means of a double-blind randomized controlled trial. A total of 141 elderly patients in the long-stay wards of six hospitals were found to be taking maintenance diuretics, and for 33 of these the drugs were judged to be mandatory. Of the remaining patients, 52 continued to receive diuretics while 54 were given matching placebo tablets. Eight in the latter group required diuretic therapy to be resumed during the following 12 weeks. The main change observed in patients who completed the trial was a slight increase of ankle oedema in the placebo group. Plasma potassium levels below 3.5 mEq/1 were found in some patients taking diuretics but not when the drugs had been withdrawn for 12 weeks. Blood pressure rose slightly in the placebo group and plasma urea rose slightly in the diuretic group. It was concluded that old people receiving long-term diuretic therapy without obvious current indication should have the drugs withdrawn under careful supervision so that those needing them could be identified.
journal_name
Age Ageingjournal_title
Age and ageingauthors
Burr ML,King S,Davies HE,Pathy MSdoi
10.1093/ageing/6.1.38subject
Has Abstractpub_date
1977-02-01 00:00:00pages
38-45issue
1eissn
0002-0729issn
1468-2834journal_volume
6pub_type
杂志文章相关文献
AGE AND AGEING文献大全abstract:Objective:To establish a consensus on the care and professional development needs of registered nurses (RNs) employed by UK care homes. Design:Two-stage, online modified Delphi study. Setting and Participants:A panel (n = 352) of individuals with experience, expertise or interest in care home nursing: (i) care home n...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw160
更新日期:2017-01-08 00:00:00
abstract::In the population study Seventy-year-old People in Göteborg, 449 70-year-old men were examined in 1971/72. Out of these, 331 were re-examined in 1976/77 at age 75, together with a cohort-comparison group of 474 70-year-old men. Cohort differences and a lower smoking prevalence at higher ages were observed. The loss of...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/11.1.45
更新日期:1982-02-01 00:00:00
abstract:BACKGROUND:the study of factors associated with age-related gait decline may assist in developing methods to preserve mobility in older people. OBJECTIVE:to examine the associations between sensorimotor factors relevant to ageing and gait in the general older population. DESIGN:cross-sectional population-based study....
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afp017
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:cranberry juice is often given to older people in hospital to prevent urinary tract infection (UTI), although there is little evidence to support its use. OBJECTIVE:to assess whether cranberry juice ingestion is effective in reducing UTIs in older people in hospital. DESIGN:randomised, placebo-controlled, ...
journal_title:Age and ageing
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ageing/afi101
更新日期:2005-05-01 00:00:00
abstract::Of 60 patients referred for geriatric assessment with clinically significant hypochromic anaemia, in the absence of frank bleeding, 44 underwent upper gastrointestinal and 27 lower gastrointestinal investigations. The probability of identifying a potential cause at upper gastrointestinal endoscopy was three times that...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/16.6.399
更新日期:1987-11-01 00:00:00
abstract::From an international comparison of arm anthropometric reference norms for the elderly a new diagnostic criterion for severe wasting malnutrition was derived: corrected arm muscle area at or below 16.0 cm2 for men or 16.9 cm2 for women. Of 201 consecutive hospital admissions aged 65 years and over, 10 subjects were ma...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/14.3.149
更新日期:1985-05-01 00:00:00
abstract::One hundred and twenty-two consecutive patients admitted with acute stroke in a carotid distribution had venous blood taken for haematocrit (Hct), haemoglobin (Hb), white cell count (WCC) and urea estimations. Patients were followed for 12 weeks to determine the influence of haematocrit upon fatality. There were 96 pa...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/17.6.406
更新日期:1988-11-01 00:00:00
abstract:BACKGROUND:There are conflicting data on the association between Helicobacter pylori (HP) infection and cardiovascular diseases. AIM:To determine if there is an association between gastric HP infection and atherosclerosis of cerebral or peripheral arteries in elderly subjects. METHODS:90 dyspeptic elderly subjects ha...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/28.4.367
更新日期:1999-07-01 00:00:00
abstract:Background:pain is prevalent in frail older adults; however, the association of pain and frailty has not been evaluated yet by a systematic assessment of prospective longitudinal studies. Objective:we aimed to assess the association of persistent pain as a risk factor for frailty incidence, using data from longitudina...
journal_title:Age and ageing
pub_type: 杂志文章,meta分析
doi:10.1093/ageing/afy104
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:(i) to describe the general practitioner utilisation of health assessments, management plans, coordination of team care arrangements and medication review item numbers within 6 months of an aged care eligibility assessment for home care packages (HCP) and (ii) investigate the impact of health assessments on t...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afaa091
更新日期:2021-01-08 00:00:00
abstract:AIM:to assess the effects of a physiotherapist-led stroke training programme for nurses working in a rehabilitation ward on clinical practice and patient outcome. METHOD:before and after group comparison with outcome assessment by observational and quantitative methods. Non-participant observation before and after the...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/28.6.567
更新日期:1999-10-01 00:00:00
abstract::A prospective study was carried out on 288 general surgical patients aged 65 years and over. Over 40% of patients suffered no post-operative complication. The commonest post-operative problem was respiratory, with 17% of patients having simple atelectasis, 12% acute bronchitis and 10% pneumonia. Six per cent of patien...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/18.5.316
更新日期:1989-09-01 00:00:00
abstract:OBJECTIVES:we investigated the exact relationship between age and gender on augmentation pressure (AG) and augmentation index (AI) measured over the radial (muscular) and carotid (elastic) arteries. DESIGN AND METHODS:AG is the contribution that wave reflection makes to systolic arterial pressure. AI is an indirect me...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afl115
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:the relationship between proximity to death and the amount of care provided by general practitioners (GPs) is largely unknown. OBJECTIVE:to examine the influence of the proximity to death on the frequency and length of GP contacts in the oldest old. STUDY DESIGN:this population-based follow-up study includ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afs062
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. METHODS:We reviewed the 2008 STOPP/START criteria to add new evidence-based...
journal_title:Age and ageing
pub_type: 杂志文章,实务指引,评审
doi:10.1093/ageing/afu145
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:residential aged care facility (RACF) resident numbers are increasing. Residents are frequently frail with substantial co-morbidity, functional and cognitive impairment with high susceptibility to acute illness. Despite living in facilities staffed by health professionals, a considerable proportion of reside...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afu117
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:our aim was to study the relationship between HbA1c and cardiovascular morbidity and all-cause mortality among older insulin-treated patients with type 2 diabetes (T2D) after adjustment for multiple confounders. METHODS:data for 4589 adults with T2D (>65 years) on insulin treatment were sourced from 532 UK ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afy178
更新日期:2019-03-01 00:00:00
abstract::Deafness is a very common problem in older persons. We present a case of metastatic adenocarcinoma of the pancreas with deafness being the patient's only reason for seeking medical attention. The patient had bilateral vestibulocochlear nerve palsies with associated lower motor neurone facial nerve palsies and a bulbar...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afs085
更新日期:2012-11-01 00:00:00
abstract::The elastic and mechanical behaviour of isolated papillar muscle was studied in aged and in young rats. The spontaneous fall in tension (stress relaxation phenomenon) and the duration of the active state of the contractile element during the isometric and isotonic contraction were greater in aged than in young rats. T...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/5.2.71
更新日期:1976-05-01 00:00:00
abstract::The cardiovascular responses to tilting and breathing were studied in 24 patients with late-onset Alzheimer's disease (AD) and 54 healthy control women aged between 75 and 96 years in order to study the parasympathetic and sympathetic heart-rate control. The cardiovascular response to tilting and breathing showed no a...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/21.4.301
更新日期:1992-07-01 00:00:00
abstract:UNLABELLED:Older people are majority users of health and social care services in the UK and internationally. Many older people who access these services have frailty, which is a state of vulnerability to adverse outcomes. The existing health care response to frailty is mainly secondary care-based and reactive to the ac...
journal_title:Age and ageing
pub_type: 杂志文章,实务指引,评审
doi:10.1093/ageing/afu138
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The benefit of endovascular thrombectomy (EVT) among nonagenarians (90 years or older) is poorly documented. We aimed to investigate the clinical and imaging factors associated with good outcomes and mortality at 90 days in nonagenarians undergoing EVT for acute ischemic stroke (AIS). METHODS:Da...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afaa243
更新日期:2020-11-17 00:00:00
abstract::In a study of two representative population samples of 70-year-olds, one of which was followed up at 75 years of age, digitalis treatment was associated with oestrogen-like metabolic effects, indicated by changes in the composition of the plasma phospholipid fraction. Digitalis treatment, at least at these ages, is re...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/11.4.261
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:to review systematically the range of case definitions and methods used to measure falls in randomised controlled trials. DESIGN/METHODS:a Cochrane review of fall prevention interventions was used to identify fall definitions in published trials. Secondary searches of various databases were used to identify ...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afi218
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:in a secondary analysis of a randomised controlled trial, we investigated whether 6 months of music-based multitask training had beneficial effects on cognitive functioning and mood in older adults. METHODS:134 community-dwellers aged ≥65 years at increased risk for falling were randomly assigned to either ...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/aft163
更新日期:2014-03-01 00:00:00
abstract::In one experiment, four groups of six-week-old-male PVG rats were, respectively, given tap water ('control group'), 0.00125M, 0.0025M, and 0.005M lathyrogen (aminoacetonitrile hydrochloride: AAN) solutions ad libitum for a period of 20 weeks. In a second experiment, 12-week-old male rats were similarly treated. It was...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/5.3.155
更新日期:1976-08-01 00:00:00
abstract::The UK has many excellent care homes that provide high-quality care for their residents; however, across the care home sector, there is a significant need for improvement. Even though the majority of care homes receive a rating of 'good' from regulators, still significant numbers are identified as requiring 'improveme...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw154
更新日期:2017-03-01 00:00:00
abstract::Forty patients over 65 years of age with fractures of the proximal femur, whose operation was delayed more than 24 hours after admission for medical reasons, were studied. Length of post-operative stay on the orthopaedic wards, mobility after one month and need for continuing supervision by the geriatric services, aft...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/20.1.41
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Eating by oneself may be a risk factor for mental illness among older adults, but may be influenced by cohabitation status. We examined the association between eating alone and depression in the context of cohabitation status in older adults in Japan. DESIGN:A longitudinal, population-based study. SETTING:...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afv145
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:age-related hearing loss is a common chronic condition; hence, it is important to understand its influence on the functional status of older adults. We assessed the association between hearing impairment with activity limitations as assessed by the activities of daily living (ADL) scale. METHODS:a total of ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afr155
更新日期:2012-03-01 00:00:00