Warfarin-associated thoracic aortic dissection in an elderly woman.

Abstract:

BACKGROUND:The risk/benefit ratio of warfarin therapy changes in the over 75s, when haemorrhagic side-effects become more common. These may not always be reported in the literature. CASE REPORT:A woman of 80 years, on long-term warfarin therapy presented with an acute dissecting thoracic aortic aneurysm; on investigation the only precipitating factor found was an international normalised ratio of 4.8. This patient, who also had an abdominal aortic aneurysm, survived, on discontinuation of her anticoagulant therapy. CONCLUSIONS:We describe a previously unreported complication of warfarin therapy in a patient over 75 years of age, to add to the cautions in prescribing this drug in patients of this age group.

journal_name

Age Ageing

journal_title

Age and ageing

authors

Blunt DM,Impallomeni MG

doi

10.1093/ageing/afh015

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

199-201

issue

2

eissn

0002-0729

issn

1468-2834

pii

33/2/199

journal_volume

33

pub_type

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