Education associated with a delayed onset of terminal decline.

Abstract:

BACKGROUND:the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. OBJECTIVE:to investigate the association of education with the onset of terminal decline in global cognitive function measured by Mini Mental State Exam (MMSE) scores. SUBJECTS:deceased participants of the Cambridge City over 75 Cohort Study who were interviewed at about 2, 7, 9, 13, 17 and 21 years after baseline. METHODS:regular and Tobit random change point growth models were fitted to MMSE scores to identify the onset of terminal decline and assess the effect of education on this onset. RESULTS:people who left school at an older age had a delayed onset of terminal decline. Thus better educated individuals experience a slightly shorter period of faster decline before death. CONCLUSION:an important finding emerging from our work is that education does appear to delay the onset of terminal decline, although only by a limited amount.

journal_name

Age Ageing

journal_title

Age and ageing

authors

Terrera GM,Minett T,Brayne C,Matthews FE

doi

10.1093/ageing/aft150

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

26-31

issue

1

eissn

0002-0729

issn

1468-2834

pii

aft150

journal_volume

43

pub_type

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