Abstract:
BACKGROUND:the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. OBJECTIVE:to investigate the association of education with the onset of terminal decline in global cognitive function measured by Mini Mental State Exam (MMSE) scores. SUBJECTS:deceased participants of the Cambridge City over 75 Cohort Study who were interviewed at about 2, 7, 9, 13, 17 and 21 years after baseline. METHODS:regular and Tobit random change point growth models were fitted to MMSE scores to identify the onset of terminal decline and assess the effect of education on this onset. RESULTS:people who left school at an older age had a delayed onset of terminal decline. Thus better educated individuals experience a slightly shorter period of faster decline before death. CONCLUSION:an important finding emerging from our work is that education does appear to delay the onset of terminal decline, although only by a limited amount.
journal_name
Age Ageingjournal_title
Age and ageingauthors
Terrera GM,Minett T,Brayne C,Matthews FEdoi
10.1093/ageing/aft150subject
Has Abstractpub_date
2014-01-01 00:00:00pages
26-31issue
1eissn
0002-0729issn
1468-2834pii
aft150journal_volume
43pub_type
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