Prevention of adverse drug reactions in hospitalized older patients with multi-morbidity and polypharmacy: the SENATOR* randomized controlled clinical trial.

abstract：:A 3-year prospective, controlled study of sports injuries in elderly athletes (over 60 years of age) treated at an outpatient sports clinic was carried out in order to determine the number, profile, and specific features of these injuries compared with those of young athletes (between 21 and 25 years). During the stud...

journal_title：Age and ageing

authors： Kannus P,Niittymäki S,Järvinen M,Lehto M

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:despite the vast literature in the area, few studies examined the large range of factors associated with physical activity (PA) in the older adult collectively, information that could help develop a supportive culture for healthy ageing. OBJECTIVE:to identify the socio-demographic, social connectedness, phy...

journal_title：Age and ageing

authors： McKee G,Kearney PM,Kenny RA

更新日期：2015-07-01 00:00:00

abstract：:An outline is given of simple urodynamic investigations applicable to elderly subjects. The type of patient presenting primarily to geriatric departments with urinary incontinence, whose management is aided by such studies, is described under various clinical groupings. The requirement for urodynamic studies and the b...

journal_title：Age and ageing

authors： Eastwood HD

更新日期：1979-02-01 00:00:00

abstract：PURPOSE:Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. METHODS:We reviewed the 2008 STOPP/START criteria to add new evidence-based...

journal_title：Age and ageing

authors： O'Mahony D,O'Sullivan D,Byrne S,O'Connor MN,Ryan C,Gallagher P

更新日期：2015-03-01 00:00:00

abstract：:To determine whether medication use differs by cognitive status among community dwelling elderly, a survey was made of a stratified random sample of 4110 black and white participants, aged 65 or older from the Duke Established Populations for Epidemiologic Studies of the Elderly in five adjacent urban and rural counti...

journal_title：Age and ageing

authors： Hanlon JT,Landerman LR,Wall WE Jr,Horner RD,Fillenbaum GG,Dawson DV,Schmader KE,Cohen HJ,Blazer DG

更新日期：1996-05-01 00:00:00

abstract：:Many studies have shown the indigenous elderly population and Asian immigrants to be groups at particular risk of vitamin D deficiency and osteomalacia, but there are no data on the risks in elderly Asians. In this community-based study a group of elderly Asians was compared with control groups of elderly and young wh...

journal_title：Age and ageing

authors： Solanki T,Hyatt RH,Kemm JR,Hughes EA,Cowan RA

更新日期：1995-03-01 00:00:00

abstract：:One hundred and sixty centenarians were discovered and followed up for 7 years (1982-88) in Shanghai. The proportion of centenarians in the population was non-significantly greater in the urban than in the rural area and centenarians were in general increasing in both areas over the years. The factors promoting longev...

journal_title：Age and ageing

authors： Zheng ZX,Wang ZS,Zhu HM,Yang JY,Peng HY,Wang LX,Li J,Jiang XW,Yu YF

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:nasogastric tube (NGT) feeding is commonly used after stroke, but its effectiveness is limited by frequent dislodgement. OBJECTIVE:the objective of the study was to evaluate looped NGT feeding in acute stroke patients with dysphagia. METHODS:this was a randomised controlled trial of 104 patients with acute...

journal_title：Age and ageing

authors： Beavan J,Conroy SP,Harwood R,Gladman JR,Leonardi-Bee J,Sach T,Bowling T,Sunman W,Gaynor C

更新日期：2010-09-01 00:00:00

abstract：:Faecal incontinence occurring at least once weekly was found in 10.3% of residents in 30 residential homes for the elderly. Fifty-two randomly-selected incontinent residents were prescribed treatment and the outcome was compared with 30 incontinent residents acting as controls. The vast majority of all incontinent res...

journal_title：Age and ageing

authors： Tobin GW,Brocklehurst JC

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:in the UK, two-thirds of patients in general hospitals are older than 70, of whom half have dementia or delirium or both. Our objective was to explore doctors, nurses and allied health professionals' perceptions of their preparation to care for confused older patients on general hospital wards....

journal_title：Age and ageing

authors： Griffiths A,Knight A,Harwood R,Gladman JR

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:to examine the association of physical activity and cardio-respiratory fitness with dehydroepiandrosterone sulphate (DHEAS), insulin-like growth factor I (IGF-I) and testosterone in healthy elderly people. DESIGN:cross-sectional study. SETTING:university research department and department of geriatric medic...

journal_title：Age and ageing

authors： Bonnefoy M,Kostka T,Patricot MC,Berthouze SE,Mathian B,Lacour JR

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Care management and assessment of need are the cornerstones of the community care reforms in the UK. Although much of the research base has been on highly vulnerable older people, in practice, care management has been implemented for a wider group. OBJECTIVE:To examine how intensive care-management at home ...

journal_title：Age and ageing

authors： Challis D,Darton R,Hughes J,Stewart K,Weiner K

更新日期：2001-09-01 00:00:00

abstract：:Data on National Health Service (NHS) dental care utilization by the elderly are analysed to consider the distribution of dental care according to the charge status of the patient. Considerable and significant differences are observed in the type and amount of dental care provided to elderly patients exempt and not ex...

journal_title：Age and ageing

authors： Birch S

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:the oldest old (85+) pose complex medical challenges. Both underdiagnosis and overdiagnosis are claimed in this group. OBJECTIVE:to estimate diagnosis, prescribing and hospital admission prevalence from 2003/4 to 2011/12, to monitor trends in medicalisation. DESIGN AND SETTING:observational study of Clinic...

journal_title：Age and ageing

authors： Melzer D,Tavakoly B,Winder RE,Masoli JA,Henley WE,Ble A,Richards SH

更新日期：2015-01-01 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) is a tremendous therapeutic advance for patients with severe aortic stenosis and high-surgical risk. Since TAVI-treated patients are elderly with multiple co-existing conditions, limited life expectancy and disproportionate health-care expenditures, the aspect of the heal...

journal_title：Age and ageing

authors： Georgiadou P,Sbarouni E,Karavolias GK,Voudris V

更新日期：2013-01-01 00:00:00

abstract：Background:Pain and delirium are common in people with dementia admitted to hospitals. These are often under-diagnosed and under-treated. Pain is implicated as a cause of delirium but this association has not been investigated in this setting. Objective:To investigate the relationship between pain and delirium in peop...

journal_title：Age and ageing

authors： Feast AR,White N,Lord K,Kupeli N,Vickerstaff V,Sampson EL

更新日期：2018-11-01 00:00:00

abstract：:We evaluated the effect of impaired hearing and vision on balance in a sample of 977 elderly people residing in the community. Of the sample, 21% reported balance problems, 27% vision problems, and 30% hearing problems. The increased relative risk for balance problems was 1.7 for each 10-year age increment. Women were...

journal_title：Age and ageing

authors： Gerson LW,Jarjoura D,McCord G

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:essential aspects of independence in community mobility among older people concern the control over where, when and how to participate (perceived autonomy), and actual mobility (life-space mobility; frequency, distance and need of assistance). We studied relationships between frailty and life-space mobility ...

journal_title：Age and ageing

authors： Portegijs E,Rantakokko M,Viljanen A,Sipilä S,Rantanen T

更新日期：2016-07-01 00:00:00

abstract：:Japan is a super-ageing society that faces pressures on its aged care system from a growing population of older adults. Naturalistic observations were undertaken at eight aged care facilities in central and northern Japan to explore how aged care is configured. Four aspects of contemporary provision were identified th...

journal_title：Age and ageing

authors： Annear MJ,Otani J,Sun J

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:exposures in childhood and adolescence may impact the development of diseases and symptoms in late life. However, evidence from low- and middle-income countries is scarce. In this cross-sectional study, we examined the association of early life risk factors with frailty amongst older adults using a large, na...

journal_title：Age and ageing

authors： Li Y,Xue QL,Odden MC,Chen X,Wu C

更新日期：2020-02-27 00:00:00

abstract：AIM:to determine the positive yield of carotid sinus massage in different patient groups: unexplained syncope, falls, dizziness and controls. DESIGN:observational study. SETTING:teaching hospital. METHODS:we studied consecutive patients over the age of 60 years referred to the 'falls clinic' with a history of unexpl...

journal_title：Age and ageing

authors： Kumar NP,Thomas A,Mudd P,Morris RO,Masud T

更新日期：2003-11-01 00:00:00

abstract：:The number of older people living with human immunodeficiency virus (HIV) in the UK is rising. Older people are at risk of acquiring HIV infection for a multitude of reasons. This, combined with effective HIV treatment which has significantly prolonged life expectancy, means that health care professionals working in t...

journal_title：Age and ageing

authors： Pratt G,Gascoyne K,Cunningham K,Tunbridge A

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:the human body composition changes with advances in age. Particularly, the central fat amount increases. Because the central fat mass is a cardiovascular risk factor, we investigated whether in an elderly population, fat mass (measured at different bodily locations) is associated with peripheral and central ...

journal_title：Age and ageing

authors： van Dijk S,van den Meiracker A,van der Cammen T,Mattace Raso F,van der Velde N

更新日期：2012-07-01 00:00:00

abstract：:To learn whether the percentage of time spent at different functional levels varies as a function of age, we studied 44 older (mean age 70 years) and 46 younger (mean age 27 years) urban, community-dwelling volunteers who participated in a study of normative ageing of the cardiovascular system. Each subject completed ...

journal_title：Age and ageing

authors： Ashworth JB,Reuben DB,Benton LA

更新日期：1994-01-01 00:00:00

abstract：:Lyme disease is an infectious disease caused by the Borrelia burgdorferi spirochetes and other related species that are transmitted through an infected tick bite. We report the case of an older patient presenting with bilateral facial palsy due to Lyme disease. Multiple non-specific clinical signs preceded facial pals...

journal_title：Age and ageing

authors： Méreaux JL,Hébant B,Magne N,Quesney G,Lefaucheur R

更新日期：2020-08-24 00:00:00

abstract：Background:overactive bladder (OAB) is a common condition in older persons. Antimuscarinic treatment remains the mainstay of treatment of OAB but clinicians have been reluctant to prescribe this to older patients. This study examined efficacy and safety information from patients >65 in fesoterodine trials to reaffirm e...

journal_title：Age and ageing

authors： Wagg A,Arumi D,Herschorn S,Angulo Cuesta J,Haab F,Ntanios F,Carlsson M,Oelke M

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:two common anti-diabetic treatments used are sitagliptin and sulphonylureas however evidence examining their comparative effectiveness in older people is limited. OBJECTIVE:to evaluate effectiveness of sitagliptin vs sulphonylureas when added to metformin in older (aged ≥75) vs younger people (18-75). DESI...

journal_title：Age and ageing

authors： Sharma M,Nazareth I,Petersen I

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Age is thought to be strongly associated with intensive care outcomes, but this relationship may be confounded by many clinical variables. OBJECTIVES:To compare clinical characteristics of elderly patients (> or = 65 years) admitted to the intensive care unit (ICU) with those in younger patients and to iden...

journal_title：Age and ageing

authors： Vosylius S,Sipylaite J,Ivaskevicius J

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVES:the absolute number of notifications for tuberculosis in older people appears to have increased in Scotland. To determine if these trends are present elsewhere in the UK, we have reviewed notifications in Leeds with particular reference to non-pulmonary disease, Asian subcontinent groups and older people. M...

journal_title：Age and ageing

authors： Phelan F,Teale C

更新日期：2000-07-01 00:00:00

abstract：Background:orthostatic hypotension (OH) is a common disabling condition associated with increased morbidity and mortality. Much of the evidence available is derived from younger populations with chronic neurological disease leading to uncertainty for the diagnosis and management of older people. Objective:to provide a...

journal_title：Age and ageing

authors： Frith J,Parry SW

更新日期：2017-03-01 00:00:00