Central but not peripheral fat mass percentage is associated with blood pressure components in the elderly.

Abstract:

BACKGROUND:the human body composition changes with advances in age. Particularly, the central fat amount increases. Because the central fat mass is a cardiovascular risk factor, we investigated whether in an elderly population, fat mass (measured at different bodily locations) is associated with peripheral and central blood pressure components. METHODS:cross-sectional design. Using dual-energy X-ray absorptiometry (DEXA), fat mass was measured within a geriatric outpatient clinic population. Blood pressure was measured with an oscillometric device, and aortic blood pressure and augmentation index (AIx) were obtained by radial artery tonometry, using the SphygmoCor system. Multivariate adjustment for confounders was performed using linear regression analyses. RESULTS:totally, 216 subjects were included (age 77.3 years ± 6.1, 34.7% male). The truncal fat mass percentage, but not the peripheral fat mass percentage, was positively associated with the peripheral systolic blood pressure (SBP) [beta 0.07 (95% CI: 0.02 to 0.11)] and the peripheral pulse pressure (PP) [beta 0.07 (95% CI: 0.02 to 0.11)], but negatively with the peripheral diastolic blood pressure (DBP) [beta -0.16 (95% CI -0.27 to -0.04)]. The truncal fat mass percentage was similarly associated with estimated aortic blood pressure components, but no association was found between the truncal fat mass percentage and the AIx. CONCLUSION:in older persons, the truncal fat mass percentage as a reflection of the central fat mass percentage, but not the peripheral fat mass percentage is associated with peripheral and aortic blood pressure components.

journal_name

Age Ageing

journal_title

Age and ageing

authors

van Dijk S,van den Meiracker A,van der Cammen T,Mattace Raso F,van der Velde N

doi

10.1093/ageing/afs056

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

534-40

issue

4

eissn

0002-0729

issn

1468-2834

pii

afs056

journal_volume

41

pub_type

杂志文章
  • Nutritional differences in patients with proximal femoral fractures.

    abstract:BACKGROUND:The reason why elderly human hips tend to break in one of two anatomical regions is uncertain. Nutritional factors may affect the site of fracture. OBJECTIVE:To assess possible nutritional differences in patients with proximal femoral fractures. DESIGN:Prospective observational cohort study. SETTING:Unive...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/28.5.458

    authors: Maffulli N,Dougall TW,Brown MT,Golden MH

    更新日期:1999-09-01 00:00:00

  • Tuberculosis in older people--is it on the increase? Trends in notifications in Leeds from 1976 to 1996.

    abstract:OBJECTIVES:the absolute number of notifications for tuberculosis in older people appears to have increased in Scotland. To determine if these trends are present elsewhere in the UK, we have reviewed notifications in Leeds with particular reference to non-pulmonary disease, Asian subcontinent groups and older people. M...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/29.4.319

    authors: Phelan F,Teale C

    更新日期:2000-07-01 00:00:00

  • Survey of 160 centenarians in Shanghai.

    abstract::One hundred and sixty centenarians were discovered and followed up for 7 years (1982-88) in Shanghai. The proportion of centenarians in the population was non-significantly greater in the urban than in the rural area and centenarians were in general increasing in both areas over the years. The factors promoting longev...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/22.1.16

    authors: Zheng ZX,Wang ZS,Zhu HM,Yang JY,Peng HY,Wang LX,Li J,Jiang XW,Yu YF

    更新日期:1993-01-01 00:00:00

  • Transcatheter aortic valve implantation: restoring the qualities of life in old age.

    abstract::Transcatheter aortic valve implantation (TAVI) is a tremendous therapeutic advance for patients with severe aortic stenosis and high-surgical risk. Since TAVI-treated patients are elderly with multiple co-existing conditions, limited life expectancy and disproportionate health-care expenditures, the aspect of the heal...

    journal_title:Age and ageing

    pub_type: 杂志文章,评审

    doi:10.1093/ageing/afs110

    authors: Georgiadou P,Sbarouni E,Karavolias GK,Voudris V

    更新日期:2013-01-01 00:00:00

  • Patterns of emergency department attendance among older people in the last three months of life and factors associated with frequent attendance: a mortality follow-back survey.

    abstract:BACKGROUND:frequent emergency department (ED) attendance at the end of life disrupts care continuity and contradicts most patients' preference for home-based care. OBJECTIVE:to examine factors associated with frequent (≥3) end of life ED attendances among older people to identify opportunities to improve care. METHOD...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afz043

    authors: Bone AE,Evans CJ,Henson LA,Gao W,Higginson IJ,BUILDCARE study.

    更新日期:2019-09-01 00:00:00

  • Cost-effectiveness of telecare for people with social care needs: the Whole Systems Demonstrator cluster randomised trial.

    abstract:PURPOSE OF THE STUDY:to examine the costs and cost-effectiveness of 'second-generation' telecare, in addition to standard support and care that could include 'first-generation' forms of telecare, compared with standard support and care that could include 'first-generation' forms of telecare. DESIGN AND METHODS:a pragm...

    journal_title:Age and ageing

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/ageing/afu067

    authors: Henderson C,Knapp M,Fernández JL,Beecham J,Hirani SP,Beynon M,Cartwright M,Rixon L,Doll H,Bower P,Steventon A,Rogers A,Fitzpatrick R,Barlow J,Bardsley M,Newman SP

    更新日期:2014-11-01 00:00:00

  • Severity of age-related hearing loss is associated with impaired activities of daily living.

    abstract:BACKGROUND:age-related hearing loss is a common chronic condition; hence, it is important to understand its influence on the functional status of older adults. We assessed the association between hearing impairment with activity limitations as assessed by the activities of daily living (ADL) scale. METHODS:a total of ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afr155

    authors: Gopinath B,Schneider J,McMahon CM,Teber E,Leeder SR,Mitchell P

    更新日期:2012-03-01 00:00:00

  • Much more medicine for the oldest old: trends in UK electronic clinical records.

    abstract:BACKGROUND:the oldest old (85+) pose complex medical challenges. Both underdiagnosis and overdiagnosis are claimed in this group. OBJECTIVE:to estimate diagnosis, prescribing and hospital admission prevalence from 2003/4 to 2011/12, to monitor trends in medicalisation. DESIGN AND SETTING:observational study of Clinic...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afu113

    authors: Melzer D,Tavakoly B,Winder RE,Masoli JA,Henley WE,Ble A,Richards SH

    更新日期:2015-01-01 00:00:00

  • Perceived age as a predictor of old age mortality: a 13-year prospective study.

    abstract:OBJECTIVES:To examine whether in older people perceived age is associated with risk of total mortality independent of chronological age. DESIGN:Prospective population-based study (Evergreen project) with mortality surveillance for 13 years after the baseline. SETTING:Face-to-face interview among community-dwelling re...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afi091

    authors: Uotinen V,Rantanen T,Suutama T

    更新日期:2005-07-01 00:00:00

  • Lower urinary tract dysfunction in Parkinson's disease: changes relate to age and not disease.

    abstract::Lower urinary tract symptoms are frequency report in Parkinson's disease. Whether these are causally related to Parkinson's disease rather than the known effects of age on the urinary tract is unknown. In this study we compared urodynamic data from 1864 women and 357 men with no neurological disease with data from 34 ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/24.6.499

    authors: Gray R,Stern G,Malone-Lee J

    更新日期:1995-11-01 00:00:00

  • Follow-up services for delirium after COVID-19-where now?

    abstract::Delirium is a common presentation in older inpatients with COVID-19, and a risk factor for cognitive decline at discharge. The glaring gaps in the service provision in delirium care, regardless of aetiology, after a hospital admission pre-existed the pandemic, but the pandemic arguably offers an opportunity now to add...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afab014

    authors: Rahman S,Byatt K

    更新日期:2021-01-22 00:00:00

  • The association between Healthy Eating Index-2005 scores and disability among older Americans.

    abstract:BACKGROUND:several studies examining diet and functional status of individuals have focused on single nutrients or food groups. Studies examining the relationship between diet and health have increasingly witnessed a shift in focus from single nutrients to overall diet quality. The objective of this study was to examin...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afr158

    authors: Xu B,Houston D,Locher JL,Zizza C

    更新日期:2012-05-01 00:00:00

  • Infective discitis as an uncommon but important cause of back pain in older people.

    abstract:CASE REPORTS:two elderly patients (aged 70 and 80 years) presented with severe back pain and restriction of spinal movements. Inflammatory markers were raised and in each case computed tomography findings confirmed infective discitis. One patient improved with antibiotics but the second developed paraplegia, a recogniz...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/29.5.454

    authors: Goel V,Young JB,Patterson CJ

    更新日期:2000-09-01 00:00:00

  • Comparative effectiveness of sitagliptin vs sulphonylureas in older people.

    abstract:BACKGROUND:two common anti-diabetic treatments used are sitagliptin and sulphonylureas however evidence examining their comparative effectiveness in older people is limited. OBJECTIVE:to evaluate effectiveness of sitagliptin vs sulphonylureas when added to metformin in older (aged ≥75) vs younger people (18-75). DESI...

    journal_title:Age and ageing

    pub_type: 杂志文章,多中心研究

    doi:10.1093/ageing/afz078

    authors: Sharma M,Nazareth I,Petersen I

    更新日期:2019-09-01 00:00:00

  • Missed diagnosis of pulmonary embolism with age-adjusted d-dimer cut-off value.

    abstract::Pulmonary embolism (PE) is a potentially severe diagnosis with high short-term mortality. Recently, age-adjusted cut-off values (age × 10 μg/l) of D-dimer were introduced to improve the diagnostic workup in older patients. In clinical practice, PE is considered 'ruled out' in patients with a non-high clinical probabil...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afw132

    authors: Stein CE,Keijsers CJ,Bootsma JE,Schouten HJ

    更新日期:2016-11-01 00:00:00

  • Quantification of proteinuria: a re-evaluation of the protein/creatinine ratio for elderly subjects.

    abstract::The difficulties of 24-hour urine collection are well recognized, especially for elderly people for whom a means of estimating protein excretion from a single casual unit sample would be preferable. We compared measurement of total urinary protein estimated by the protein/creatinine ratio with 24-h urine collection an...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/22.6.443

    authors: Mitchell SC,Sheldon TA,Shaw AB

    更新日期:1993-11-01 00:00:00

  • The association between life course socioeconomic position and life satisfaction in different welfare states: European comparative study of individuals in early old age.

    abstract:BACKGROUND:whether socioeconomic position over the life course influences the wellbeing of older people similarly in different societies is not known. OBJECTIVE:to investigate the magnitude of socioeconomic inequalities in life satisfaction among individuals in early old age and the influence of the welfare state regi...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afu004

    authors: Niedzwiedz CL,Katikireddi SV,Pell JP,Mitchell R

    更新日期:2014-05-01 00:00:00

  • Neighbourhood deprivation and incident mobility disability in older adults.

    abstract:OBJECTIVE:to assess whether incident mobility disability and neighbourhood deprivation in older people are associated independent of the effects of individual socio-economic status, health behaviours and health status. METHODS:prospective cohort study with a 2-year follow-up. SETTING:the English Longitudinal Study of...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afn092

    authors: Lang IA,Llewellyn DJ,Langa KM,Wallace RB,Melzer D

    更新日期:2008-07-01 00:00:00

  • Validity of direct assessment of functional status as a tool for measuring Alzheimer's disease severity.

    abstract:OBJECTIVE:to assess the validity of the Direct Assessment of Functional Status (DAFS) performance-based functional scale for the staging of dementia severity by comparing it with established clinical, functional and cognitive scales. PATIENTS AND METHODS:93 consecutive Alzheimer's disease patients underwent DAFS. Soci...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/27.5.615

    authors: Zanetti O,Frisoni GB,Rozzini L,Bianchetti A,Trabucchi M

    更新日期:1998-09-01 00:00:00

  • An evaluation of the efficacy and safety of tetrahydroaminoacridine (THA) without lecithin in the treatment of Alzheimer's disease.

    abstract::Seventy-nine patients with probable Alzheimer's disease were enrolled into a double-blind, placebo-controlled cross-over study to assess the therapeutic effect and safety of THA (tetrahydroaminoacridine; tacrine) without concomitant lecithin administration. Forty-one patients completed the trial which consisted of two...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/22.5.316

    authors: Wilcock GK,Surmon DJ,Scott M,Boyle M,Mulligan K,Neubauer KA,O'Neill D,Royston VH

    更新日期:1993-09-01 00:00:00

  • Effects of a physiotherapist-led stroke training programme for nurses.

    abstract:AIM:to assess the effects of a physiotherapist-led stroke training programme for nurses working in a rehabilitation ward on clinical practice and patient outcome. METHOD:before and after group comparison with outcome assessment by observational and quantitative methods. Non-participant observation before and after the...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/28.6.567

    authors: Forster A,Dowswell G,Young J,Sheard J,Wright P,Bagley P

    更新日期:1999-10-01 00:00:00

  • Evidence for the validity of the Short-form 36 Questionnaire (SF-36) in an elderly population.

    abstract::The objective of this study was to determine whether the Short-form 36 Health Status Questionnaire (SF-36) is suitable for use in an elderly population. The SF-36 was administered by interview to a random sample of 827 adults from West Glamorgan. Among the 216 adults aged 65 and over the data were 98.8% complete. Evid...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/23.3.182

    authors: Lyons RA,Perry HM,Littlepage BN

    更新日期:1994-05-01 00:00:00

  • Time-efficient physical activity interventions to reduce blood pressure in older adults: a randomised controlled trial.

    abstract:BACKGROUND:Hypertension is a risk factor for both cardiovascular and cerebrovascular disease, with an increasing incidence with advancing patient age. Exercise interventions have the potential to reduce blood pressure in older adults, however, rates of exercise uptake and adherence are low, with 'lack of time' a common...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afaa211

    authors: Herrod PJJ,Lund JN,Phillips BE

    更新日期:2020-10-17 00:00:00

  • Age and the rate of induction of aryl hydrocarbon hydroxylase in isolated peripheral blood monocytes.

    abstract::We have measured the rate of induction of the microsomal monooxygenase enzyme aryl hydrocarbon hydroxylase (AHH) in isolated peripheral blood monocytes from young and elderly donors. There was no effect of age on rate of induction. The mechanisms underlying impaired induction of drug metabolism in elderly people remai...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/20.6.421

    authors: George G,Wynne H,Woodhouse K

    更新日期:1991-11-01 00:00:00

  • Suicide and parasuicide in old age: a review.

    abstract::The disproportionately high suicide rate among the elderly is examined in this review. As opposed to younger age groups, a close association exists between suicide and parasuicide in old age. Factors associated with these events include a high incidence of depression, serious physical illness, as well as social factor...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/7.4.201

    authors: Shulman K

    更新日期:1978-11-01 00:00:00

  • STOPP/START version 2-development of software applications: easier said than done?

    abstract::Explicit criteria, such as the STOPP/START criteria, are increasingly used both in clinical practice and in research to identify potentially inappropriate prescribing in older people. In an article on the STOPP/START criteria version 2, O'Mahony et al have pointed out the advantages of developing computerised criteria...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afw114

    authors: Anrys P,Boland B,Degryse JM,De Lepeleire J,Petrovic M,Marien S,Dalleur O,Strauven G,Foulon V,Spinewine A

    更新日期:2016-09-01 00:00:00

  • Will drugs help patients with Alzheimer's disease?

    abstract::Recent studies have shown a defect in the cholinergic system of the cerebral cortex of patients suffering from nonvascular senile dementia. This observation suggests the possibility of instituting some kind of replacement therapy and trial have been carried out. At this juncture it seem pertinent to ask what lessons c...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/8.2.86

    authors: Kendall MJ

    更新日期:1979-05-01 00:00:00

  • Myocardial contractility in aged rats.

    abstract::The elastic and mechanical behaviour of isolated papillar muscle was studied in aged and in young rats. The spontaneous fall in tension (stress relaxation phenomenon) and the duration of the active state of the contractile element during the isometric and isotonic contraction were greater in aged than in young rats. T...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/5.2.71

    authors: Minelli R,Reggiani C,De Nicola P

    更新日期:1976-05-01 00:00:00

  • Temporal trends in impairments of physical function among older adults during 2001-16 in Sweden: towards a healthier ageing.

    abstract:Background:a trend towards decline in disability has been reported in older adults, but less is known about corresponding temporal trends in measured physical functions. Objective:to verify these trends during 2001-16 in an older Swedish population. Methods:functional status was assessed at three occasions: 2001-04 (...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afy085

    authors: Santoni G,Angleman SB,Ek S,Heiland EG,Lagergren M,Fratiglioni L,Welmer AK

    更新日期:2018-09-01 00:00:00

  • Immunogenicity of inactivated influenza vaccine in residential homes for elderly people.

    abstract::One hundred and seventy residents of 11 Leicester City Council homes for the elderly, with a total of 515 beds, were studied during a 30-week period from September 1988 to March 1989 to determine the use of influenza vaccine, the levels of influenza antibody, the incidence of influenza, and the protection afforded by ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/21.3.182

    authors: Nicholson KG,Baker DJ,Chakraverty P,Farquhar A,Hurd D,Kent J,Litton PA,Smith SH

    更新日期:1992-05-01 00:00:00