An evaluation of the efficacy and safety of tetrahydroaminoacridine (THA) without lecithin in the treatment of Alzheimer's disease.

abstract：OBJECTIVES:The objectives of this study were to (i) survey the risk factors for NSAID gastropathy in outpatients (elderly patients in the community), compared to those living in old people's homes or nursing homes, (ii) study the prescription of medication prophylaxis during use of NSAIDs conform the current national g...

journal_title：Age and ageing

authors： van Leen MW,van der Eijk I,Schols JM

更新日期：2007-07-01 00:00:00

abstract：INTRODUCTION:care home residents have high healthcare needs not fully met by prevailing healthcare models. This study explored how healthcare configuration influences resource use. METHODS:a realist evaluation using qualitative and quantitative data from case studies of three UK health and social care economies select...

journal_title：Age and ageing

authors： Gordon AL,Goodman C,Davies SL,Dening T,Gage H,Meyer J,Schneider J,Bell B,Jordan J,Martin FC,Iliffe S,Bowman C,Gladman JRF,Victor C,Mayrhofer A,Handley M,Zubair M

更新日期：2018-07-01 00:00:00

abstract：:The Neuberger report failed to show that the Liverpool Care Pathway was the cause of poor end-of-life care and made it the scapegoat for poor communication and faulty decision-making. The report's discrediting of a quality assurance mechanism that had the potential for improvement is a disservice to dying patients. Se...

journal_title：Age and ageing

authors： Regnard C

更新日期：2014-03-01 00:00:00

abstract：INTRODUCTION:national reports have highlighted deficiencies in care provided to older surgical patients and suggested a role for innovative, collaborative, inter-specialty models of care. The extent of geriatrician-led perioperative services in the UK (excluding orthogeriatric services) has not previously been describe...

journal_title：Age and ageing

authors： Partridge JS,Collingridge G,Gordon AL,Martin FC,Harari D,Dhesi JK

更新日期：2014-09-01 00:00:00

abstract：:High rates of mortality are an abiding feature of homes for the elderly. Almost a fifth (19.2%) of a cohort of 6947 residents died in the 12 months following initial assessment. Survival rates vary widely, however, for different groups within the residential population. Using data from a longitudinal study of 175 home...

journal_title：Age and ageing

authors： Booth T,Phillips D,Barritt A,Berry S,Martin DN,Melotte C

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:the recognition of stroke symptoms by the public and activation of the emergency medical services (EMS) are the most important factors in instigating pre-hospital stroke care. Studies have suggested that poor recognition of the warning signs of stroke is the main cause of delay in accessing the EMS. METHODS...

journal_title：Age and ageing

authors： Jones SP,Jenkinson AJ,Leathley MJ,Watkins CL

更新日期：2010-01-01 00:00:00

abstract：:In a city where specialist homes for the elderly mentally infirm (EMI) have been extensively developed, a study was carried out to determine if residents in such homes were mentally impaired to a degree intermediate between that of residents in ordinary homes, and those in psychogeriatric beds. The study, using valid ...

journal_title：Age and ageing

authors： de Zoysa AS,Blessed G

更新日期：1984-07-01 00:00:00

abstract：INTRODUCTION:a professional man sustained a residual, persisting, isolated impairment of short-term memory secondary to severe carbon monoxide poisoning. Informal, open trial of the cholinesterase inhibitor donepezil resulted in uncertain benefit. PROTOCOL:an N-of-1 randomized, double-blind controlled trial of donepez...

journal_title：Age and ageing

authors： Price JD,Grimley Evans J

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:the empirical Dignity Model has profoundly influenced the provision of palliative care for older terminally ill patients in the West, as it provides practical guidance and intervention strategies for promoting dignity and reducing distress at the end-of-life. OBJECTIVE:to examine the concept of 'living and ...

journal_title：Age and ageing

authors： Ho AH,Chan CL,Leung PP,Chochinov HM,Neimeyer RA,Pang SM,Tse DM

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:this study investigated the prospective associations of accelerometer assessed daily steps with subsequent depressive symptoms in older adults. METHODS:a 2-year prospective study was performed in the community. A total of 285 older adults ≥65 years (mean age = 74.5) attended the baseline assessment in 2012....

journal_title：Age and ageing

authors： Hsueh MC,Stubbs B,Lai YJ,Sun CK,Chen LJ,Ku PW

更新日期：2020-09-25 00:00:00

abstract：OBJECTIVE:to examine the association of physical activity and cardio-respiratory fitness with dehydroepiandrosterone sulphate (DHEAS), insulin-like growth factor I (IGF-I) and testosterone in healthy elderly people. DESIGN:cross-sectional study. SETTING:university research department and department of geriatric medic...

journal_title：Age and ageing

authors： Bonnefoy M,Kostka T,Patricot MC,Berthouze SE,Mathian B,Lacour JR

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:there are around 100,000 new stroke cases and over a million people living with its consequences annually in the UK. This has large impacts on health and social care, unpaid carers and lost productivity. We aimed to estimate associated costs. METHODS:we estimated 2014/2015 annual mean cost per person and ag...

journal_title：Age and ageing

authors： Patel A,Berdunov V,Quayyum Z,King D,Knapp M,Wittenberg R

更新日期：2020-02-27 00:00:00

abstract：:Among 352 residents of a home for the elderly, who were fully mobile and devoid of most predisposing factors for bacteriuria, 19% of men and 27% of women had two positive cultures within two months. Positive conversion at one year among men and women negative at entry was 11% and 23% respectively, negative conversion ...

journal_title：Age and ageing

authors： Kasviki-Charvati P,Drolette-Kefakis B,Papanayiotou PC,Dontas AS

更新日期：1982-08-01 00:00:00

abstract：Background:overactive bladder (OAB) is a common condition in older persons. Antimuscarinic treatment remains the mainstay of treatment of OAB but clinicians have been reluctant to prescribe this to older patients. This study examined efficacy and safety information from patients >65 in fesoterodine trials to reaffirm e...

journal_title：Age and ageing

authors： Wagg A,Arumi D,Herschorn S,Angulo Cuesta J,Haab F,Ntanios F,Carlsson M,Oelke M

更新日期：2017-07-01 00:00:00

abstract：:Vaginal pessaries are widely considered to be a safe alternative to surgery in older women. We report a case of near fatal septicaemia in a 75-year-old woman associated with a shelf pessary, the presence of which was identified during an exploratory laparotomy. This case highlights the importance of the gynaecological...

journal_title：Age and ageing

authors： Wheeler LD,Lazarus R,Torkington J,O'Mahony MS,Woodhouse KW

更新日期：2004-09-01 00:00:00

abstract：:Mild cognitive impairment (MCI) is a common clinical syndrome that identifies people at high risk of developing dementia. Although treatments for MCI are currently unavailable, preliminary evidence has identified potential neuro-protective effects of physical activity, which may lead to improved outcomes. However, the...

journal_title：Age and ageing

authors： Barber SE,Clegg AP,Young JB

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Delirium is a common neuropsychiatric disorder. The natural course is of an acute, fluctuating and often transient condition; however, accumulating evidence suggests that delirium can be associated with incomplete recovery. Despite a growing body of research, a lack of clarity exists regarding definition and...

journal_title：Age and ageing

authors： Adamis D,Devaney A,Shanahan E,McCarthy G,Meagher D

更新日期：2015-03-01 00:00:00

abstract：UNLABELLED:Delirium is one of the foremost unmet medical needs in healthcare. It affects one in eight hospitalised patients and is associated with multiple adverse outcomes including increased length of stay, new institutionalisation, and considerable patient distress. Recent studies also show that delirium strongly pr...

journal_title：Age and ageing

authors： Maclullich AM,Anand A,Davis DH,Jackson T,Barugh AJ,Hall RJ,Ferguson KJ,Meagher DJ,Cunningham C

更新日期：2013-11-01 00:00:00

abstract：:Of 212 cases of peritonitis found in a retrospective study of geriatric inpatients, the most common causes were mesenteric infarction, malignancy, intestinal obstruction, perforated peptic ulcer, cholecystitis, diverticulitis and perforation of the urinary bladder. The diagnostic accuracy was 47%. Abdominal pain had b...

journal_title：Age and ageing

authors： Wroblewski M,Mikulowski P

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:there is limited evidence of a protective effect of physical activity in preventing hip fractures among older people living in institutions and in those aged 80 or over. OBJECTIVE:to examine the relationship between physical activity and risk of hip fracture in frail older people. DESIGN:a case-control stu...

journal_title：Age and ageing

authors： Norton R,Galgali G,Campbell AJ,Reid IR,Robinson E,Butler M,Gray H

更新日期：2001-05-01 00:00:00

abstract：:Resuscitation decisions during the first 6 weeks were analysed for 97 admissions to a psychogeriatric ward of a general teaching hospital. Seventy-seven patients (79%) had a written 'do not resuscitate' (DNR) order on admission and 74 patients (875) had a written DNR order after 6 weeks. Morbidity was assessed with a ...

journal_title：Age and ageing

authors： Dautzenberg PL,Hooyer C,Schonwetter RS,Dermout KM,vd Veer JK,Duursma SA

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To compare the levels of satisfaction expressed by residents of nursing homes with those of patients in geriatric long-stay wards. DESIGN:A structured satisfaction questionnaire containing 37 closed and two open questions was used to elicit responses from residents of nursing homes in the former South West T...

journal_title：Age and ageing

authors： Higgs PF,MacDonald LD,MacDonald JS,Ward MC

更新日期：1998-03-01 00:00:00

abstract：Background:a trend towards decline in disability has been reported in older adults, but less is known about corresponding temporal trends in measured physical functions. Objective:to verify these trends during 2001-16 in an older Swedish population. Methods:functional status was assessed at three occasions: 2001-04 (...

journal_title：Age and ageing

authors： Santoni G,Angleman SB,Ek S,Heiland EG,Lagergren M,Fratiglioni L,Welmer AK

更新日期：2018-09-01 00:00:00

abstract：:The type of environmental hazards implicated in the aetiology of a consecutive series of 787 hip-fracture patients was prospectively studied. Most falls occurred between 09 h 00 and midday and there was no seasonal variation. Fifty-one different environmental hazards were implicated in the aetiology of the fall for 58...

journal_title：Age and ageing

authors： Parker MJ,Twemlow TR,Pryor GA

更新日期：1996-07-01 00:00:00

abstract：:The frequency of snoring was studied in 46 patients with Alzheimer's disease (AD), 37 with multiinfarct dementia (MID), and in a random sample of 124 elderly community residents without known diseases affecting higher cortical functions. The demented patients were reported to snore twice as frequently as the control s...

journal_title：Age and ageing

authors： Erkinjuntti T,Partinen M,Sulkava R,Palomaki H,Tilvis R

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:to investigate the associations between chronic health conditions, psychosocial and environmental factors and catastrophic decline in mobility among older people. DESIGN:longitudinal cohort. SETTING:national sample living in private households. PARTICIPANTS:nine hundred and ninety-nine adults aged > or = 6...

journal_title：Age and ageing

authors： Ayis S,Gooberman-Hill R,Bowling A,Ebrahim S

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:to ascertain the value of employing a specialist clinician's contribution to the assessment of older people prior to care home entry. DESIGN:randomised controlled trial. METHOD:256 older people at risk of care home entry were randomly allocated to either a control group, who received the usual care manageme...

journal_title：Age and ageing

authors： Challis D,Clarkson P,Williamson J,Hughes J,Venables D,Burns A,Weinberg A

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:to assess motivating factors of healthy elderly people to comply with influenza vaccination. DESIGN:survey of healthy elderly people invited by mail by their general practitioner to come for influenza vaccination. Compliance and the personal characteristics of gender, age and medical insurance were recorded ...

journal_title：Age and ageing

authors： van Essen GA,Kuyvenhoven MM,de Melker RA

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:antipsychotics are widely used in assisted living (AL facilities). Even more, the prescription of these drugs is gradually increasing since the availability of second-generation atypical antipsychotics. More knowledge is needed on prescription reasons to understand this increasing prevalence. METHODS:cross-...

journal_title：Age and ageing

authors： Larrayadieu A,Abellan van Kan G,Piau A,Soto Martin M,Nourhashemi F,Rolland Y,Vellas B

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:physical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death. METHODS:in the Women's Health Initiativ...

journal_title：Age and ageing

authors： Saquib N,Brunner R,Desai M,Kroenke C,Martin LW,Daviglus M,Allen NB,Robinson J,Tindle H,Stefanick ML

更新日期：2019-05-01 00:00:00