An N-of-1 randomized controlled trial ('N-of-1 trial') of donepezil in the treatment of non-progressive amnestic syndrome.

abstract：BACKGROUND:in a secondary analysis of a randomised controlled trial, we investigated whether 6 months of music-based multitask training had beneficial effects on cognitive functioning and mood in older adults. METHODS:134 community-dwellers aged ≥65 years at increased risk for falling were randomly assigned to either ...

journal_title：Age and ageing

authors： Hars M,Herrmann FR,Gold G,Rizzoli R,Trombetti A

更新日期：2014-03-01 00:00:00

abstract：Objective:to investigate whether cognitive impairment, measured early after Emergency Department (ED) arrival and irrespective of its cause, is independently associated with functional decline or mortality after 3 and 12 months in older ED patients. Design and setting:a prospective multi-centre cohort study in all Acu...

journal_title：Age and ageing

authors： Lucke JA,de Gelder J,Heringhaus C,van der Mast RC,Fogteloo AJ,Anten S,Blauw GJ,de Groot B,Mooijaart SP

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:the purpose of this study was to evaluate the likelihood that the presence of certain medical conditions in older ambulatory patients are associated with the risk of developing a new pressure ulcer. DESIGN:a cohort study. SETTING AND SUBJECTS:a large outpatient record database from the United Kingdom calle...

journal_title：Age and ageing

authors： Margolis DJ,Knauss J,Bilker W,Baumgarten M

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:delirium is a frequent complication of hospital admission for older people and can be reduced by multicomponent interventions, but implementation and delivery of such interventions is challenging. OBJECTIVE:to investigate fidelity to the prevention of delirium system of care within a multicentre, pragmatic,...

journal_title：Age and ageing

authors： Smith J,Green J,Siddiqi N,Inouye SK,Collinson M,Farrin A,Young J

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:early mobilization after hip fracture (HF) is an important predictor of outcome, but knowledge of the consequences of not achieving the pre-fracture basic mobility status in acute hospital recovery is sparse. OBJECTIVE:we examined whether the regain of pre-fracture basic mobility status evaluated with the c...

journal_title：Age and ageing

authors： Kristensen MT,Öztürk B,Röck ND,Ingeman A,Palm H,Pedersen AB

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:dysphagia is common in acute stroke. Accurate detection of the presence or absence of aspiration by bedside swallowing assessment is difficult without objective methods, tending to over-diagnose aspiration. As a result, some patients suffer restricted oral intake unnecessarily. OBJECTIVE:we examined the pre...

journal_title：Age and ageing

authors： Smith HA,Lee SH,O'Neill PA,Connolly MJ

更新日期：2000-11-01 00:00:00

abstract：INTRODUCTION:care home residents have high healthcare needs not fully met by prevailing healthcare models. This study explored how healthcare configuration influences resource use. METHODS:a realist evaluation using qualitative and quantitative data from case studies of three UK health and social care economies select...

journal_title：Age and ageing

authors： Gordon AL,Goodman C,Davies SL,Dening T,Gage H,Meyer J,Schneider J,Bell B,Jordan J,Martin FC,Iliffe S,Bowman C,Gladman JRF,Victor C,Mayrhofer A,Handley M,Zubair M

更新日期：2018-07-01 00:00:00

abstract：:The frequency of snoring was studied in 46 patients with Alzheimer's disease (AD), 37 with multiinfarct dementia (MID), and in a random sample of 124 elderly community residents without known diseases affecting higher cortical functions. The demented patients were reported to snore twice as frequently as the control s...

journal_title：Age and ageing

authors： Erkinjuntti T,Partinen M,Sulkava R,Palomaki H,Tilvis R

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:To evaluate whether older patients with pyogenic liver abscess have distinctive presenting features or if their management differs from that of younger patients. DESIGN:Retrospective chart review of all cases occurring from 1982 to 1992. SETTING:A regional trauma centre and two large community hospitals. P...

journal_title：Age and ageing

authors： Smoger SH,Mitchell CK,McClave SA

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:to ascertain the value of employing a specialist clinician's contribution to the assessment of older people prior to care home entry. DESIGN:randomised controlled trial. METHOD:256 older people at risk of care home entry were randomly allocated to either a control group, who received the usual care manageme...

journal_title：Age and ageing

authors： Challis D,Clarkson P,Williamson J,Hughes J,Venables D,Burns A,Weinberg A

更新日期：2004-01-01 00:00:00

abstract：Background/Objective:studies on the association of dementia with specific body composition (BC) components are scarce. Our aim was to investigate associations of BC measures with different levels of cognitive function in late-life. Methods:we studied 5,169 participants (mean age 76 years, 42.9% men) in the AGES-Reykja...

journal_title：Age and ageing

authors： Spauwen PJ,Murphy RA,Jónsson PV,Sigurdsson S,Garcia ME,Eiriksdottir G,van Boxtel MP,Lopez OL,Gudnason V,Harris TB,Launer LJ

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:to explore views on advance care planning in care homes for older people. DESIGN:qualitative exploration of views from care home staff and the family of residents in care homes for older people. SETTING:all care homes for the elderly in two London Boroughs. PARTICIPANTS:staff (care managers, nurses and car...

journal_title：Age and ageing

authors： Stewart F,Goddard C,Schiff R,Hall S

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:the data concerning the predictive role of oxidised LDL (ox-LDL) in all-cause mortality are scarce. We investigated whether circulating ox-LDL would stand out as a risk factor of total mortality in the elderly. Study subjects, design and methods: a total of 1,260 elderly inhabitants (533 men, 7...

journal_title：Age and ageing

authors： Linna M,Ahotupa M,Löppönen MK,Irjala K,Vasankari T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Some patients may have medication-related risk factors only identified by home visits, but the extent to which those risk factors are associated with poor health outcomes remains unclear. OBJECTIVE:To determine the association between medication-related risk factors and poor patient health outcomes from obs...

journal_title：Age and ageing

authors： Sorensen L,Stokes JA,Purdie DM,Woodward M,Roberts MS

更新日期：2005-11-01 00:00:00

abstract：Background:orthostatic hypotension (OH) is a common disabling condition associated with increased morbidity and mortality. Much of the evidence available is derived from younger populations with chronic neurological disease leading to uncertainty for the diagnosis and management of older people. Objective:to provide a...

journal_title：Age and ageing

authors： Frith J,Parry SW

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:the empirical Dignity Model has profoundly influenced the provision of palliative care for older terminally ill patients in the West, as it provides practical guidance and intervention strategies for promoting dignity and reducing distress at the end-of-life. OBJECTIVE:to examine the concept of 'living and ...

journal_title：Age and ageing

authors： Ho AH,Chan CL,Leung PP,Chochinov HM,Neimeyer RA,Pang SM,Tse DM

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:(i) to describe the general practitioner utilisation of health assessments, management plans, coordination of team care arrangements and medication review item numbers within 6 months of an aged care eligibility assessment for home care packages (HCP) and (ii) investigate the impact of health assessments on t...

journal_title：Age and ageing

authors： Visvanathan R,Amare AT,Lang C,Khadka J,Yu S,Beilby J,Wesselingh S,Inacio MC

更新日期：2021-01-08 00:00:00

abstract：BACKGROUND:arterial stiffening is a marker of vascular ageing and an independent risk factor for cardiovascular disease. A potential mechanism linking cardiovascular disease to chronic kidney disease might be the change in arterial elasticity. We aim to determine the association between renal function and arterial stif...

journal_title：Age and ageing

authors： Sedaghat S,Dawkins Arce FG,Verwoert GC,Hofman A,Ikram MA,Franco OH,Dehghan A,Witteman JC,Mattace-Raso F

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:the nursing home Resident Assessment Instrument (RAI) includes a set of core assessment items, known as the Minimum Data Set (MDS), for assessment and care screening and more detailed Resident Assessment Protocols in 18 areas that represent common problem areas or risk factors for nursing home residents. Its...

journal_title：Age and ageing

authors： Hawes C,Morris JN,Phillips CD,Fries BE,Murphy K,Mor V

更新日期：1997-09-01 00:00:00

abstract：:Pulmonary embolism (PE) is a potentially severe diagnosis with high short-term mortality. Recently, age-adjusted cut-off values (age × 10 μg/l) of D-dimer were introduced to improve the diagnostic workup in older patients. In clinical practice, PE is considered 'ruled out' in patients with a non-high clinical probabil...

journal_title：Age and ageing

authors： Stein CE,Keijsers CJ,Bootsma JE,Schouten HJ

更新日期：2016-11-01 00:00:00

abstract：:The Rivermead ADL scale was developed for assessing activities of daily living in stroke patients but was not validated for elderly subjects. This study was designed to validate the scale for patients aged over 64 years. A series of 150 stroke patients was assessed on the scale, of whom 103 were aged over 64 years. Th...

journal_title：Age and ageing

authors： Lincoln NB,Edmans JA

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:there is limited evidence of a protective effect of physical activity in preventing hip fractures among older people living in institutions and in those aged 80 or over. OBJECTIVE:to examine the relationship between physical activity and risk of hip fracture in frail older people. DESIGN:a case-control stu...

journal_title：Age and ageing

authors： Norton R,Galgali G,Campbell AJ,Reid IR,Robinson E,Butler M,Gray H

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:age-related differences in the treatment of lung cancer patients have been reported in the past, but most previous studies have not recorded case-mix factors, nor have they studied the impact of such ageism on survival. METHODS:a questionnaire-based study of diagnostic and case-mix factors was carried out a...

journal_title：Age and ageing

authors： Peake MD,Thompson S,Lowe D,Pearson MG,Participating Centres.

更新日期：2003-03-01 00:00:00

abstract：:Formal assessment of cognitive decline with cognitive tests can be difficult, requiring either two measurement points or a comparison of 'hold' with 'don't hold' tests. Informant-based assessment provides an alternative approach because informants can adopt a longitudinal perspective and directly rate cognitive change...

journal_title：Age and ageing

authors： Jorm AF,Christensen H,Henderson AS,Jacomb PA,Korten AE,Mackinnon A

更新日期：1996-03-01 00:00:00

abstract：PRESENTATION:an 83-year-old man was admitted to hospital with acute confusion 3 days after a direct flight from Australia. OUTCOME:computed tomography (CT) brain scan and magnetic resonance imaging head scan revealed the cause to be pneumocephalus, apparently the result of barotrauma caused by Valsalva manoeuvres when...

journal_title：Age and ageing

authors： Chan YP,Yau CY,Lewis RR,Kinirons MT

更新日期：2000-07-01 00:00:00

abstract：:In this study we examine whether the introduction of a clerking pro forma improves the completeness of the recording of the management of stroke patients and we review methodological issues important in this type of audit. We prospectively identified 244 consecutive stroke patients before and after the introduction of...

journal_title：Age and ageing

authors： Davenport RJ,Dennis MS,Warlow CP

更新日期：1995-01-01 00:00:00

abstract：UNLABELLED:Older people are majority users of health and social care services in the UK and internationally. Many older people who access these services have frailty, which is a state of vulnerability to adverse outcomes. The existing health care response to frailty is mainly secondary care-based and reactive to the ac...

journal_title：Age and ageing

authors： Turner G,Clegg A,British Geriatrics Society.,Age UK.,Royal College of General Practioners.

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:physical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death. METHODS:in the Women's Health Initiativ...

journal_title：Age and ageing

authors： Saquib N,Brunner R,Desai M,Kroenke C,Martin LW,Daviglus M,Allen NB,Robinson J,Tindle H,Stefanick ML

更新日期：2019-05-01 00:00:00

abstract：IMPORTANCE:risk factors for delirium in hospital inpatients are well established, but less is known about whether delirium occurring in the community or during an emergency admission to hospital care might be predicted from routine primary-care records. OBJECTIVES:identify risk factors in primary-care electronic healt...

journal_title：Age and ageing

authors： Bowman K,Jones L,Masoli J,Mujica-Mota R,Strain D,Butchart J,Valderas JM,Fortinsky RH,Melzer D,Delgado J

更新日期：2020-04-27 00:00:00

abstract：OBJECTIVES:Previous research has indicated that age-related medical or health conditions can affect driving performance in older adults but little, if any, research has examined the mechanisms through which health conditions affect driving difficulties in older adults. DESIGN:Cross-sectional, correlational study. SET...

journal_title：Age and ageing

authors： Tuokko HA,Rhodes RE,Dean R

更新日期：2007-07-01 00:00:00