Ageism in the management of lung cancer.

Abstract:

BACKGROUND:age-related differences in the treatment of lung cancer patients have been reported in the past, but most previous studies have not recorded case-mix factors, nor have they studied the impact of such ageism on survival. METHODS:a questionnaire-based study of diagnostic and case-mix factors was carried out across 48 hospital Trusts in the UK between 1997 and 1998. We identified 1,652 patients and followed through with regard to their treatment and survival for 6 months after diagnosis. RESULTS:the median age of the population was 69 years, and for this analysis, was divided into three age groups: under 65 years, 65-74 and 75 years and over. There were significant inverse correlations between age and histological diagnosis, any active treatment and survival, even when corrected for case-mix factors and non-cancer causes of death. For example, the surgical resection rate in patients with confirmed non-small cell lung cancer with good performance status, no chronic obstructive pulmonary disease and limited disease was 37% in the younger patients compared with 15% in those 75 and over. The overall mortality rates at 6 months ranged from 42% in patients under 65 to 58% in the over 75s. CONCLUSIONS:this national study of lung cancer care in the UK has shown large age-related differences in management and survival in patients with lung cancer, largely independent of case-mix factors. The reasons for this are complex but such under-treatment in the elderly may be one factor underlying the poor outcomes in lung cancer patients in the UK.

journal_name

Age Ageing

journal_title

Age and ageing

authors

Peake MD,Thompson S,Lowe D,Pearson MG,Participating Centres.

doi

10.1093/ageing/32.2.171

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

171-7

issue

2

eissn

0002-0729

issn

1468-2834

journal_volume

32

pub_type

杂志文章
  • Caring for a dying spouse at the end of life: 'It's one of the things you volunteer for when you get married': a qualitative study of the oldest carers' experiences.

    abstract:BACKGROUND:older people aged 80 and over are increasingly providing end-of-life care to spouses at home and often do so for long periods of time, while also trying to manage their own illnesses and disabilities. Little of the research on older spousal carers has focussed on the oldest carers; hence, the needs of this p...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afw047

    authors: Turner M,King C,Milligan C,Thomas C,Brearley SG,Seamark D,Wang X,Blake S,Payne S

    更新日期:2016-05-01 00:00:00

  • Quantification of proteinuria: a re-evaluation of the protein/creatinine ratio for elderly subjects.

    abstract::The difficulties of 24-hour urine collection are well recognized, especially for elderly people for whom a means of estimating protein excretion from a single casual unit sample would be preferable. We compared measurement of total urinary protein estimated by the protein/creatinine ratio with 24-h urine collection an...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/22.6.443

    authors: Mitchell SC,Sheldon TA,Shaw AB

    更新日期:1993-11-01 00:00:00

  • Preventing delirium: should non-pharmacological, multicomponent interventions be used? A systematic review and meta-analysis of the literature.

    abstract:BACKGROUND:Delirium is a complex neuropsychiatric syndrome that is common among elderly inpatients. It has been associated with increased mortality, longer hospital stays, cognitive and functional decline and increased institutionalisation rates. Multicomponent interventions, a series of non-pharmacological strategies ...

    journal_title:Age and ageing

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/ageing/afu173

    authors: Martinez F,Tobar C,Hill N

    更新日期:2015-03-01 00:00:00

  • Four-year clinical results of transcatheter self-expanding Medtronic CoreValve implantation in high-risk patients with severe aortic stenosis.

    abstract:BACKGROUND:transcatheter aortic valve implantation (TAVI) has emerged as an alternative to surgical aortic valve replacement for patients with severe aortic stenosis considered inoperable or at high operative risk, but the long-term outcome remains unknown. HYPOTHESIS:we assessed the 4-year clinical and echocardiograp...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afw038

    authors: Thomopoulou S,Vavuranakis M,Karyofyllis P,Kariori M,Karavolias G,Balanika M,Smyrli A,Stefopoulos C,Sbarouni E,Moldovan C,Khoury M,Stefanadis C,Voudris V

    更新日期:2016-05-01 00:00:00

  • Trends in hip fracture incidence and mortality in Chinese population from Hong Kong 2001-09.

    abstract:BACKGROUND:there is a suggestion that while the age-adjusted incidence of hip fracture in the West may be declining, the incidence may be rising in Asia. OBJECTIVE:this study examines the incidence and post-fracture mortality from 2001 to 2009 among the population aged 65 years and over. METHODS:hip fracture incidenc...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afs177

    authors: Chau PH,Wong M,Lee A,Ling M,Woo J

    更新日期:2013-03-01 00:00:00

  • Survival of elderly men with congestive heart failure.

    abstract::Congestive heart failure (CHF) is the most common discharge diagnosis for elderly patients. The survival of elderly (age greater than or equal to 75 years) patients with CHF has not recently been reported, especially with reference to left ventricular ejection fraction (LVEF). A patient database was searched for the d...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/21.1.49

    authors: Taffet GE,Teasdale TA,Bleyer AJ,Kutka NJ,Luchi RJ

    更新日期:1992-01-01 00:00:00

  • A systematic review of outcomes following emergency transfer to hospital for residents of aged care facilities.

    abstract:BACKGROUND:residential aged care facility (RACF) resident numbers are increasing. Residents are frequently frail with substantial co-morbidity, functional and cognitive impairment with high susceptibility to acute illness. Despite living in facilities staffed by health professionals, a considerable proportion of reside...

    journal_title:Age and ageing

    pub_type: 杂志文章,评审

    doi:10.1093/ageing/afu117

    authors: Dwyer R,Gabbe B,Stoelwinder JU,Lowthian J

    更新日期:2014-11-01 00:00:00

  • Factors associated with hospital deaths in the oldest old: a cross-sectional study.

    abstract:AIMS/OBJECTIVES:to study associations between the likelihood of hospital death with patient demographics, cause of death and co-morbidities for people aged ≥85 at death who have been previously admitted (within 12 months of death) to hospital. METHODS:a cross-sectional study, using death registration data and hospital...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afw019

    authors: Pocock LV,Ives A,Pring A,Verne J,Purdy S

    更新日期:2016-05-01 00:00:00

  • Impact of lifestyle factors on fracture risk in older patients with cardiovascular disease: a prospective cohort study of 26,335 individuals from 40 countries.

    abstract:BACKGROUND:fractures are a major health concern among the elderly. People at risk for cardiovascular disease (CVD) are at an increased risk for fractures. The aim of this study was to assess the individual and combined effect of the CVD risk factors of smoking, alcohol consumption and physical activity on fracture risk...

    journal_title:Age and ageing

    pub_type: 杂志文章,多中心研究

    doi:10.1093/ageing/afu009

    authors: Khatib R,Yusuf S,Barzilay JI,Papaioannou A,Thabane L,Gao P,Joseph PG,Teo K,Mente A

    更新日期:2014-09-01 00:00:00

  • Age-associated change in pain threshold measured by transcutaneous neuronal electrical stimulation.

    abstract::The measurement of cutaneous pain threshold using the Neuromod Selectra Model 7750 Transcutaneous Neuronal Electrical Stimulator is described. Pain threshold, measured in 520 healthy volunteers aged 5-105 years, increased with age. Consistent values were obtained in 22 healthy volunteers on three successive days. Pain...

    journal_title:Age and ageing

    pub_type: 杂志文章,评审

    doi:10.1093/ageing/18.4.241

    authors: Tucker MA,Andrew MF,Ogle SJ,Davison JG

    更新日期:1989-07-01 00:00:00

  • Effect of a lathyrogen (aminoacetonitrile hydrochloride) on aortic physiosclerosis and skeletal mineralization in growing rats of different age.

    abstract::In one experiment, four groups of six-week-old-male PVG rats were, respectively, given tap water ('control group'), 0.00125M, 0.0025M, and 0.005M lathyrogen (aminoacetonitrile hydrochloride: AAN) solutions ad libitum for a period of 20 weeks. In a second experiment, 12-week-old male rats were similarly treated. It was...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/5.3.155

    authors: Morgan AJ,Bellamy D

    更新日期:1976-08-01 00:00:00

  • Lower urinary tract dysfunction in Parkinson's disease: changes relate to age and not disease.

    abstract::Lower urinary tract symptoms are frequency report in Parkinson's disease. Whether these are causally related to Parkinson's disease rather than the known effects of age on the urinary tract is unknown. In this study we compared urodynamic data from 1864 women and 357 men with no neurological disease with data from 34 ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/24.6.499

    authors: Gray R,Stern G,Malone-Lee J

    更新日期:1995-11-01 00:00:00

  • Tuberculosis in older people--is it on the increase? Trends in notifications in Leeds from 1976 to 1996.

    abstract:OBJECTIVES:the absolute number of notifications for tuberculosis in older people appears to have increased in Scotland. To determine if these trends are present elsewhere in the UK, we have reviewed notifications in Leeds with particular reference to non-pulmonary disease, Asian subcontinent groups and older people. M...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/29.4.319

    authors: Phelan F,Teale C

    更新日期:2000-07-01 00:00:00

  • Measures of physical functioning after hip fracture: construct validity and responsiveness of performance-based and self-reported measures.

    abstract:OBJECTIVES:this study aimed to investigate the construct validity and responsiveness of performance-based and self-reported measures of strength, mobility and balance after hip fracture. DESIGN:secondary analysis of clinical trial data. SUBJECTS:a total of 148 older people undergoing hip fracture rehabilitation. MET...

    journal_title:Age and ageing

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/ageing/afs090

    authors: Farag I,Sherrington C,Kamper SJ,Ferreira M,Moseley AM,Lord SR,Cameron ID

    更新日期:2012-09-01 00:00:00

  • Best practice guidelines for the management of frailty: a British Geriatrics Society, Age UK and Royal College of General Practitioners report.

    abstract:UNLABELLED:Older people are majority users of health and social care services in the UK and internationally. Many older people who access these services have frailty, which is a state of vulnerability to adverse outcomes. The existing health care response to frailty is mainly secondary care-based and reactive to the ac...

    journal_title:Age and ageing

    pub_type: 杂志文章,实务指引,评审

    doi:10.1093/ageing/afu138

    authors: Turner G,Clegg A,British Geriatrics Society.,Age UK.,Royal College of General Practioners.

    更新日期:2014-11-01 00:00:00

  • Why should medical students study Social Gerontology?

    abstract::The General Medical Council (GMC) provides a core curriculum for all medical degrees in the UK. However, these guidelines do not provide in-depth, specific learning outcomes for the various medical specialties. Recognising our ageing population, the British Geriatrics Society in 2013 published their own supplementary ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afw003

    authors: Tinker A,Hussain L,D'Cruz JL,Tai WY,Zaidman S

    更新日期:2016-03-01 00:00:00

  • Older people in accident and emergency departments.

    abstract::Older people attend accident and emergency departments more frequently than younger people. However, most assessments indicate that this higher level of use is appropriate and is the result of more serious injury and illness among this population. Older patients discharged from accident and emergency departments are f...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/30.suppl_3.3

    authors: Burns E

    更新日期:2001-08-01 00:00:00

  • Hip fracture risk and subsequent mortality among Alzheimer's disease patients in the United Kingdom, 1988-2007.

    abstract:BACKGROUND:hip fractures result in a significant burden to the patient, their caregivers and the health care system. Patients with Alzheimer's disease (AD) have a higher incidence of hip fracture compared with other older people without AD, although it is not clear if AD is an independent risk factor for hip fracture. ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afq146

    authors: Baker NL,Cook MN,Arrighi HM,Bullock R

    更新日期:2011-01-01 00:00:00

  • High normal plasma triglycerides are associated with preserved cognitive function in Chinese oldest-old.

    abstract:OBJECTIVE:to explore the relationship between blood lipids/lipoproteins and cognitive function in the Chinese oldest-old. DESIGN:multivariate statistical analysis using cross-sectional data. SETTING:community-based setting in longevity areas in China. SUBJECTS:eight hundred and thirty-six subjects aged 80 and older ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afs033

    authors: Yin ZX,Shi XM,Kraus VB,Fitzgerald SM,Qian HZ,Xu JW,Zhai Y,Sereny MD,Zeng Y

    更新日期:2012-09-01 00:00:00

  • Health-related quality of life and antihypertensive medication adherence among older adults.

    abstract:PURPOSE:health-related quality of life (HRQOL) is an important psycho-social characteristic which may impact an individual's ability to manage their chronic disease. We examined the association between HRQOL and antihypertensive medication adherence in older adults. METHODS:participants were part of a cohort study of ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afq040

    authors: Holt EW,Muntner P,Joyce CJ,Webber L,Krousel-Wood MA

    更新日期:2010-07-01 00:00:00

  • Visual acuity and contrast sensitivity in relation to falls in an elderly population.

    abstract::Visual acuity and contrast sensitivity were measured in 95 residents of a hostel for the aged (mean age = 83 years) using a dual-contrast letter chart and the Melbourne Edge Test (MET). Vision (as measured by visual acuity, the MET, low-contrast visual acuity, and difference between high- and low-contrast acuity) decr...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/20.3.175

    authors: Lord SR,Clark RD,Webster IW

    更新日期:1991-05-01 00:00:00

  • Poor oral hygiene, oral microorganisms and aspiration pneumonia risk in older people in residential aged care: a systematic review.

    abstract:BACKGROUND:aspiration pneumonia increases hospitalisation and mortality of older people in residential aged care. OBJECTIVES:determine potentially pathogenic microorganisms in oral specimens of older people with aspiration pneumonia and the effect of professional oral care in reducing aspiration pneumonia risk. DATA ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afaa102

    authors: Khadka S,Khan S,King A,Goldberg LR,Crocombe L,Bettiol S

    更新日期:2021-01-08 00:00:00

  • Regaining pre-fracture basic mobility status after hip fracture and association with post-discharge mortality and readmission-a nationwide register study in Denmark.

    abstract:BACKGROUND:early mobilization after hip fracture (HF) is an important predictor of outcome, but knowledge of the consequences of not achieving the pre-fracture basic mobility status in acute hospital recovery is sparse. OBJECTIVE:we examined whether the regain of pre-fracture basic mobility status evaluated with the c...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afy185

    authors: Kristensen MT,Öztürk B,Röck ND,Ingeman A,Palm H,Pedersen AB

    更新日期:2019-03-01 00:00:00

  • Catheter-associated urinary tract infection in primary and community health care.

    abstract:INTRODUCTION:Although often a last resort, urinary catheterisation is a relatively common management option for bladder dysfunction in older people and others cared for in community settings. Catheter-associated urinary tract infection (CAUTI) is a well-recognised source of increased morbidity and economic burden in ac...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afl052

    authors: Getliffe K,Newton T

    更新日期:2006-09-01 00:00:00

  • Severity of age-related hearing loss is associated with impaired activities of daily living.

    abstract:BACKGROUND:age-related hearing loss is a common chronic condition; hence, it is important to understand its influence on the functional status of older adults. We assessed the association between hearing impairment with activity limitations as assessed by the activities of daily living (ADL) scale. METHODS:a total of ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afr155

    authors: Gopinath B,Schneider J,McMahon CM,Teber E,Leeder SR,Mitchell P

    更新日期:2012-03-01 00:00:00

  • Postural orientation and equilibrium: what do we need to know about neural control of balance to prevent falls?

    abstract::Postural control is no longer considered simply a summation of static reflexes but, rather, a complex skill based on the interaction of dynamic sensorimotor processes. The two main functional goals of postural behaviour are postural orientation and postural equilibrium. Postural orientation involves the active alignme...

    journal_title:Age and ageing

    pub_type: 杂志文章,评审

    doi:10.1093/ageing/afl077

    authors: Horak FB

    更新日期:2006-09-01 00:00:00

  • Total anticholinergic burden and risk of mortality and cardiovascular disease over 10 years in 21,636 middle-aged and older men and women of EPIC-Norfolk prospective population study.

    abstract:BACKGROUND:Studies have raised concerns that medications with anticholinergic property have potential adverse effects on health outcomes. OBJECTIVES:The objective of this study is to examine the prospective relationships between total anticholinergic burden (ACB) from medications and mortality, and cardiovascular dise...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afu185

    authors: Myint PK,Fox C,Kwok CS,Luben RN,Wareham NJ,Khaw KT

    更新日期:2015-03-01 00:00:00

  • A modelling-based economic evaluation of primary-care-based fall-risk screening followed by fall-prevention intervention: a cohort-based Markov model stratified by older age groups.

    abstract:BACKGROUND:fall-risk assessment with fall-prevention intervention referral for at-risk groups to avoid falls could be cost-effective from a care-payer perspective. AIMS:to model the cost-effectiveness of a fall-risk assessment (QTUG compared to TUG) with referral to one of four fall-prevention interventions (Otago, Fa...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afz125

    authors: Franklin M,Hunter RM

    更新日期:2019-12-01 00:00:00

  • A re-validation of the Rivermead ADL scale for elderly patients with stroke.

    abstract::The Rivermead ADL scale was developed for assessing activities of daily living in stroke patients but was not validated for elderly subjects. This study was designed to validate the scale for patients aged over 64 years. A series of 150 stroke patients was assessed on the scale, of whom 103 were aged over 64 years. Th...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/19.1.19

    authors: Lincoln NB,Edmans JA

    更新日期:1990-01-01 00:00:00

  • Improving the recording of the clinical assessment of stroke patients using a clerking pro forma.

    abstract::In this study we examine whether the introduction of a clerking pro forma improves the completeness of the recording of the management of stroke patients and we review methodological issues important in this type of audit. We prospectively identified 244 consecutive stroke patients before and after the introduction of...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/24.1.43

    authors: Davenport RJ,Dennis MS,Warlow CP

    更新日期:1995-01-01 00:00:00