Circulating oxidised LDL lipids, when proportioned to HDL-c, emerged as a risk factor of all-cause mortality in a population-based survival study.

abstract：OBJECTIVE:chronic obstructive pulmonary disease (COPD) prevalence steadily increases with age. However, the effectiveness of inhaled therapy in the elderly COPD population has rarely been formally evaluated. We studied a group of elderly patients with COPD with a range of severity, selected from one General Practice re...

journal_title：Age and ageing

authors： Jarvis S,Ind PW,Shiner RJ

更新日期：2007-03-01 00:00:00

abstract：:A study was carried out to examine the prevalence of oropharyngeal and urinary tract colonization and to compare the colonizing bacteria with the strains causing nosocomial infections during patients' stays in a geriatric ward. Colonization with Gram-negative rods was not uncommon. Nosocomial infections frequently occ...

journal_title：Age and ageing

authors： Michielsen W,Vandevondele D,Verschraegen G,Claeys G,Afschrift M

更新日期：1993-05-01 00:00:00

abstract：Background:overactive bladder (OAB) is a common condition in older persons. Antimuscarinic treatment remains the mainstay of treatment of OAB but clinicians have been reluctant to prescribe this to older patients. This study examined efficacy and safety information from patients >65 in fesoterodine trials to reaffirm e...

journal_title：Age and ageing

authors： Wagg A,Arumi D,Herschorn S,Angulo Cuesta J,Haab F,Ntanios F,Carlsson M,Oelke M

更新日期：2017-07-01 00:00:00

abstract：Objective:to investigate a high-intensity functional exercise (HIFE) group in hospitalised older adults. Design:assessor-blinded, randomised-controlled trial. Setting:sub-acute wards at a metropolitan rehabilitation hospital. Participants:older adults ≥65 years (n = 468) able to stand with minimum assistance or less...

journal_title：Age and ageing

authors： Raymond MJ,Jeffs KJ,Winter A,Soh SE,Hunter P,Holland AE

更新日期：2017-03-01 00:00:00

abstract：:A straight abdominal radiograph can be used in the elderly to indicate a loaded colon. Two groups of patients were identified using radiology, one with faeces-filled caeca and the other with gas-filled caeca. Gastro-intestinal transit time measurements and breath methane analysis, an indicator of colonic bacterial act...

journal_title：Age and ageing

authors： McKay LF,Smith RG,Eastwood MA,Walsh SD,Cruikshank JG

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Valproate (VPA) is an antiepileptic drug with a broad spectrum of efficacy. Although usually well-tolerated, it may have side-effects of which encephalopathy is one of the most serious. OBJECTIVE:To describe the clinical characteristics of valproate encephalopathy (VE) in five older patients with remote sym...

journal_title：Age and ageing

authors： Beyenburg S,Back C,Diederich N,Lewis M,Reuber M

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:home visits and telephone calls are two often used approaches in transitional care, but their differential economic effects are unknown. OBJECTIVE:to examine the differential economic benefits of home visits with telephone calls and telephone calls only in transitional discharge support. DESIGN:cost-effect...

journal_title：Age and ageing

authors： Wong FK,So C,Chau J,Law AK,Tam SK,McGhee S

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:the Oxfordshire Community Stroke Project (OCSP) devised a simple clinical classification for acute stroke which predicted mortality, functional recovery and patterns of recurrent stroke. We aimed to determine whether this could predict the presence of carotid disease and be used to select which patients with...

journal_title：Age and ageing

authors： Mead GE,Shingler H,Farrell A,O'Neill PA,McCollum CN

更新日期：1998-11-01 00:00:00

abstract：Objective:To establish a consensus on the care and professional development needs of registered nurses (RNs) employed by UK care homes. Design:Two-stage, online modified Delphi study. Setting and Participants:A panel (n = 352) of individuals with experience, expertise or interest in care home nursing: (i) care home n...

journal_title：Age and ageing

authors： Cooper E,Spilsbury K,McCaughan D,Thompson C,Butterworth T,Hanratty B

更新日期：2017-01-08 00:00:00

abstract：:A study of 414 elderly residents of sheltered accommodation in West Essex investigated the degree to which health, physical handicap and support from community care services affected dental needs and utilization of dental services. The study population had a mean age of 77 years, 77% lived alone, 17% were housebound a...

journal_title：Age and ageing

authors： Tobias B

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:fall-risk assessment with fall-prevention intervention referral for at-risk groups to avoid falls could be cost-effective from a care-payer perspective. AIMS:to model the cost-effectiveness of a fall-risk assessment (QTUG compared to TUG) with referral to one of four fall-prevention interventions (Otago, Fa...

journal_title：Age and ageing

authors： Franklin M,Hunter RM

更新日期：2019-12-01 00:00:00

abstract：:Clinical observations suggest an age-associated decline in skin perfusion but there are few quantitative in vivo data on skin perfusion at various ages. We studied skin perfusion of the dorsum of the foot by determining the capillary blood flow velocity (CBFV) expressed in millivolts (mV), using laser Doppler flowmetr...

journal_title：Age and ageing

authors： Weiss M,Milman B,Rosen B,Eisenstein Z,Zimlichman R

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:transcatheter aortic valve implantation (TAVI) has emerged as an alternative to surgical aortic valve replacement for patients with severe aortic stenosis considered inoperable or at high operative risk, but the long-term outcome remains unknown. HYPOTHESIS:we assessed the 4-year clinical and echocardiograp...

journal_title：Age and ageing

authors： Thomopoulou S,Vavuranakis M,Karyofyllis P,Kariori M,Karavolias G,Balanika M,Smyrli A,Stefopoulos C,Sbarouni E,Moldovan C,Khoury M,Stefanadis C,Voudris V

更新日期：2016-05-01 00:00:00

abstract：:Fasting serum cholesterol and triglyceride levels, and lipoprotein electrophoretic patterns have been investigated in 42 men aged 67-92 years (mean 79 years). Although all the cholesterol and the majority of the triglyceride levels were within the normal range for younger people, both were significantly greater (P < 0...

journal_title：Age and ageing

authors： Horsey J,Livesley B,Dickerson JW

更新日期：1980-08-01 00:00:00

abstract：:Clinical assessments have to be used in epidemiological studies in the absence of more objective means of establishing diagnosis or recording events in the natural history of disease. This requires the standardization of definition, technique and interpretation as a means of reducing observer variability in clinical e...

journal_title：Age and ageing

authors： Garraway WM,Akhtar AJ,Gore SM,Prescott RJ,Smith RG

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVES:To compare costs and outcome of occupational therapy-led assessment with social worker-led assessment of older people, in terms of their independence and quality of life. DESIGN:Cost-effectiveness analysis alongside a randomised controlled trial. The analysis took viewpoints of health services and patients....

journal_title：Age and ageing

authors： Flood C,Mugford M,Stewart S,Harvey I,Poland F,Lloyd-Smith W

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:arterial stiffening is a marker of vascular ageing and an independent risk factor for cardiovascular disease. A potential mechanism linking cardiovascular disease to chronic kidney disease might be the change in arterial elasticity. We aim to determine the association between renal function and arterial stif...

journal_title：Age and ageing

authors： Sedaghat S,Dawkins Arce FG,Verwoert GC,Hofman A,Ikram MA,Franco OH,Dehghan A,Witteman JC,Mattace-Raso F

更新日期：2014-11-01 00:00:00

abstract：Introduction:identifying the most at risk older people in Emergency Departments (EDs) may help guide clinical practice, and service improvement in emergency care, but little is known about how to implement such tools in practice. Methods:consensus building was used to determine the desirable characteristics of a risk ...

journal_title：Age and ageing

authors： Elliott A,Phelps K,Regen E,Conroy SP

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:in recent years, the NHS has been accused of ageism frequently and from many fronts. Previous studies have shown that the number of critical care beds in the UK is inadequate to meet the needs of the population. This study asks whether there is discrimination against older people in access to these critical ...

journal_title：Age and ageing

authors： Hubbard RE,Lyons RA,Woodhouse KW,Hillier SL,Wareham K,Ferguson B,Major E

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:to test the hypothesis as to whether persons newly discharged into the community following an acute stroke and assigned a stroke case manager would experience, compared to usual post-hospital care, better health-related quality of life (HRQL), fewer emergency room visits and less non-elective hospitalisation...

journal_title：Age and ageing

authors： Mayo NE,Nadeau L,Ahmed S,White C,Grad R,Huang A,Yaffe MJ,Wood-Dauphinee S

更新日期：2008-01-01 00:00:00

abstract：:In Hong Kong, about 15% of older people (aged 80 and above) live in care homes, one of the highest proportions in the world. During the spread of severe acute respiratory syndrome in 2003, the crude fatality rate for older people in care homes that were infected was 72%. After taking the advice of a team of internatio...

journal_title：Age and ageing

authors： Chow L

更新日期：2021-01-08 00:00:00

abstract：Background:there is growing consensus around the importance of population level approaches which seek to improve public knowledge and awareness of dementia. Aim:to assess knowledge of the relationship between dementia and ageing, and of the risk and protective factors associated with it, among the general public in Ir...

journal_title：Age and ageing

authors： Glynn RW,Shelley E,Lawlor BA

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:aspiration pneumonia increases hospitalisation and mortality of older people in residential aged care. OBJECTIVES:determine potentially pathogenic microorganisms in oral specimens of older people with aspiration pneumonia and the effect of professional oral care in reducing aspiration pneumonia risk. DATA ...

journal_title：Age and ageing

authors： Khadka S,Khan S,King A,Goldberg LR,Crocombe L,Bettiol S

更新日期：2021-01-08 00:00:00

abstract：:A simple random sample of older people composed of 215 men and 272 women aged 62 years and over was examined in Edinburgh in 1968-9. After one year, 86 per cent of the men and 79 per cent of the women were re-examined; 7 per cent of the men and 4 per cent of the women had died and the remainder were not re-examined fo...

journal_title：Age and ageing

authors： Milne JS,Chopin JM

更新日期：1975-08-01 00:00:00

abstract：OBJECTIVE:to investigate auditory function in subjects with early Alzheimer's disease, mild cognitive impairment and with subjective memory complaints, in search of signs of central auditory processing dysfunction even in early stages of cognitive impairment. DESIGN AND SUBJECTS:a consecutive group of men and women, r...

journal_title：Age and ageing

authors： Idrizbegovic E,Hederstierna C,Dahlquist M,Kämpfe Nordström C,Jelic V,Rosenhall U

更新日期：2011-03-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) isolated from patients with Alzheimer's disease to produce interleukin-1 and -2 (IL-1, IL-2) was compared to that of cells from age-matched controls and young healthy subjects. There was no difference in the production of both interleukins between patients and ...

journal_title：Age and ageing

authors： Bessler H,Sirota P,Hart J,Djaldetti M

更新日期：1989-01-01 00:00:00

abstract：:Older people attend accident and emergency departments more frequently than younger people. However, most assessments indicate that this higher level of use is appropriate and is the result of more serious injury and illness among this population. Older patients discharged from accident and emergency departments are f...

journal_title：Age and ageing

authors： Burns E

更新日期：2001-08-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs are currently being investigated as agents to reduce the incidence and progression of Alzheimer's disease. Paradoxically they have also been reported to induce deleterious effects on the central nervous system, including aseptic meningitis and cognitive decline in the elderly. We ...

journal_title：Age and ageing

authors： Ashton D,Kim P,Griffiths N,Beran R

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVES:Previous research has indicated that age-related medical or health conditions can affect driving performance in older adults but little, if any, research has examined the mechanisms through which health conditions affect driving difficulties in older adults. DESIGN:Cross-sectional, correlational study. SET...

journal_title：Age and ageing

authors： Tuokko HA,Rhodes RE,Dean R

更新日期：2007-07-01 00:00:00

abstract：Background:harmful alcohol consumption is reported to be increasing in older people. To intervene and reduce associated risks, evidence currently available needs to be identified. Methods:two systematic reviews in older populations (55+ years): (1) Interventions to prevent or reduce excessive alcohol consumption; (2) ...

journal_title：Age and ageing

authors： Kelly S,Olanrewaju O,Cowan A,Brayne C,Lafortune L

更新日期：2018-03-01 00:00:00