Is there a role for physical activity in preventing cognitive decline in people with mild cognitive impairment?

abstract：Background:high cardiorespiratory fitness (CRF) is associated with larger brain volumes but data on sex differences in the association of CRF with brain volumes are scarce. We investigated whether the association of CRF with total grey matter (GM) and white matter volumes as well as medial temporal lobe and striatum vo...

journal_title：Age and ageing

authors： Pentikäinen H,Ngandu T,Liu Y,Savonen K,Komulainen P,Hallikainen M,Kivipelto M,Rauramaa R,Soininen H

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:Age limits for diagnostics and treatments have been largely removed and replaced by an active diagnostic and treatment practice among the oldest old and has led to concerns about potential overtreatment during the last years of life. METHODS:Use of prescription medication in the last years of life was ass...

journal_title：Age and ageing

authors： Pedersen JK,Jensen TM,Waldorff FB,Søndergaard J,Christensen K

更新日期：2020-10-23 00:00:00

abstract：OBJECTIVE:to review systematically the range of case definitions and methods used to measure falls in randomised controlled trials. DESIGN/METHODS:a Cochrane review of fall prevention interventions was used to identify fall definitions in published trials. Secondary searches of various databases were used to identify ...

journal_title：Age and ageing

authors： Hauer K,Lamb SE,Jorstad EC,Todd C,Becker C,PROFANE-Group.

更新日期：2006-01-01 00:00:00

abstract：:A study is reported of the religious beliefs, attitudes, and practice of old people in the West of Scotland, based on a questionnaire given to 501 people aged 65 years and over randomly selected from those living at home. Almost all had had a full range of religious instruction, and regarded their parents as religious...

journal_title：Age and ageing

authors： Reid WS,Gilmore AJ,Andrews GR,Caird FI

更新日期：1978-02-01 00:00:00

abstract：:From an international comparison of arm anthropometric reference norms for the elderly a new diagnostic criterion for severe wasting malnutrition was derived: corrected arm muscle area at or below 16.0 cm2 for men or 16.9 cm2 for women. Of 201 consecutive hospital admissions aged 65 years and over, 10 subjects were ma...

journal_title：Age and ageing

authors： Friedman PJ,Campbell AJ,Caradoc-Davies TH

更新日期：1985-05-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) isolated from patients with Alzheimer's disease to produce interleukin-1 and -2 (IL-1, IL-2) was compared to that of cells from age-matched controls and young healthy subjects. There was no difference in the production of both interleukins between patients and ...

journal_title：Age and ageing

authors： Bessler H,Sirota P,Hart J,Djaldetti M

更新日期：1989-01-01 00:00:00

abstract：:We analysed 103 episodes of upper gastrointestinal bleeding in 88 elderly patients (age 76 +/- 7.7 years) to determine which of a group of 52 clinical and laboratory variables, measured on admission, best predicted continued or rebleeding, and death in these patients. Variables which related directly to the size of th...

journal_title：Age and ageing

authors： Booker JA,Johnston M,Booker CI,Tydd T,Mitchell R

更新日期：1987-07-01 00:00:00

abstract：:This is the second in an occasional series of paired commentaries in Age and Ageing, the Journal of the British Geriatrics Society and the Journal of the American Geriatrics Society (JAGS). The aim is to address issues of current significance and to foster dialogue and increased understanding between academics and cli...

journal_title：Age and ageing

authors： Pollock K,Seymour J

更新日期：2018-05-01 00:00:00

abstract：:We present two cases of acute hepatotoxicity associated with elevated paracetamol (acetaminophen) levels in older patients. Both patients were receiving a standard European dose of oral paracetamol (2 × 500 mg QDS) with no risk factors for slowed metabolism (weight <50 kg, interacting medications, hepatic enzyme induc...

journal_title：Age and ageing

authors： Ging P,Mikulich O,O'Reilly KM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:dementia is associated with an excess risk of death but mortality after chronic subdural hematoma (CSDH) evacuation in older people with dementia is unknown. We assessed the association between dementia and 1-year case-fatality in older persons undergoing CSDH evacuation. METHODS:we conducted a nationwide F...

journal_title：Age and ageing

authors： Tommiska P,Korja M,Siironen J,Kaprio J,Raj R

更新日期：2020-10-06 00:00:00

abstract：:Guidelines state that doctors should reveal the diagnosis to the carer and the person with dementia. Carers may, however, not wish the diagnosis to be disclosed. We investigated carer and patient characteristics associated with the wish for disclosure. Fifty-four per cent of 100 carers wished the diagnosis to be revea...

journal_title：Age and ageing

authors： Fahy M,Wald C,Walker Z,Livingston G

更新日期：2003-07-01 00:00:00

abstract：Background:despite an increasing proportion of older people working beyond State Pension Age (SPA), little is known about neither the motivations for this decision nor whether, and to what extent, working beyond SPA affects quality of life (QoL). Methods:QoL was measured using the CASP-19 scale. Respondents in paid wo...

journal_title：Age and ageing

authors： Di Gessa G,Corna L,Price D,Glaser K

更新日期：2018-05-01 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) is a tremendous therapeutic advance for patients with severe aortic stenosis and high-surgical risk. Since TAVI-treated patients are elderly with multiple co-existing conditions, limited life expectancy and disproportionate health-care expenditures, the aspect of the heal...

journal_title：Age and ageing

authors： Georgiadou P,Sbarouni E,Karavolias GK,Voudris V

更新日期：2013-01-01 00:00:00

abstract：UNLABELLED:Delirium is one of the foremost unmet medical needs in healthcare. It affects one in eight hospitalised patients and is associated with multiple adverse outcomes including increased length of stay, new institutionalisation, and considerable patient distress. Recent studies also show that delirium strongly pr...

journal_title：Age and ageing

authors： Maclullich AM,Anand A,Davis DH,Jackson T,Barugh AJ,Hall RJ,Ferguson KJ,Meagher DJ,Cunningham C

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:(i) to describe the general practitioner utilisation of health assessments, management plans, coordination of team care arrangements and medication review item numbers within 6 months of an aged care eligibility assessment for home care packages (HCP) and (ii) investigate the impact of health assessments on t...

journal_title：Age and ageing

authors： Visvanathan R,Amare AT,Lang C,Khadka J,Yu S,Beilby J,Wesselingh S,Inacio MC

更新日期：2021-01-08 00:00:00

abstract：BACKGROUND:the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. OBJECTIVE:to investigate the association of education with the onset of terminal decline in g...

journal_title：Age and ageing

authors： Terrera GM,Minett T,Brayne C,Matthews FE

更新日期：2014-01-01 00:00:00

abstract：:Japan is a super-ageing society that faces pressures on its aged care system from a growing population of older adults. Naturalistic observations were undertaken at eight aged care facilities in central and northern Japan to explore how aged care is configured. Four aspects of contemporary provision were identified th...

journal_title：Age and ageing

authors： Annear MJ,Otani J,Sun J

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:to explore the relationship between blood lipids/lipoproteins and cognitive function in the Chinese oldest-old. DESIGN:multivariate statistical analysis using cross-sectional data. SETTING:community-based setting in longevity areas in China. SUBJECTS:eight hundred and thirty-six subjects aged 80 and older ...

journal_title：Age and ageing

authors： Yin ZX,Shi XM,Kraus VB,Fitzgerald SM,Qian HZ,Xu JW,Zhai Y,Sereny MD,Zeng Y

更新日期：2012-09-01 00:00:00

abstract：AIM:to determine the positive yield of carotid sinus massage in different patient groups: unexplained syncope, falls, dizziness and controls. DESIGN:observational study. SETTING:teaching hospital. METHODS:we studied consecutive patients over the age of 60 years referred to the 'falls clinic' with a history of unexpl...

journal_title：Age and ageing

authors： Kumar NP,Thomas A,Mudd P,Morris RO,Masud T

更新日期：2003-11-01 00:00:00

abstract：:This review considers the changes in salivary glands associated with ageing and concludes that there is no evidence to show that xerostomia is likely to result from the ageing process alone. The four main factors causing xerostomia are presented and it can be seen that the condition is a side-effect of diseases and th...

journal_title：Age and ageing

authors： Ettinger RL

更新日期：1996-09-01 00:00:00

abstract：:The effects of discontinuing long-term diuretic therapy were investigated by means of a double-blind randomized controlled trial. A total of 141 elderly patients in the long-stay wards of six hospitals were found to be taking maintenance diuretics, and for 33 of these the drugs were judged to be mandatory. Of the rema...

journal_title：Age and ageing

authors： Burr ML,King S,Davies HE,Pathy MS

更新日期：1977-02-01 00:00:00

abstract：:The effect of leukoaraiosis or white matter low attenuation (WMLA) on cognitive function is not fully understood. We compared the neuropsychological performance of 37 Alzheimer's disease patients with WMLA on CT brain scans with a similar group of 31 Alzheimer's disease patients with no evidence of white matter lesion...

journal_title：Age and ageing

authors： Amar K,Bucks RS,Lewis T,Scott M,Wilcock GK

更新日期：1996-11-01 00:00:00

abstract：:Congestive heart failure (CHF) is the most common discharge diagnosis for elderly patients. The survival of elderly (age greater than or equal to 75 years) patients with CHF has not recently been reported, especially with reference to left ventricular ejection fraction (LVEF). A patient database was searched for the d...

journal_title：Age and ageing

authors： Taffet GE,Teasdale TA,Bleyer AJ,Kutka NJ,Luchi RJ

更新日期：1992-01-01 00:00:00

abstract：:The aim of the present study was to determine the prevalence of biliary lithiasis (BL) and its major associated factors in the elderly people of a small town in Sicily. All inhabitants over the age of 65 were interviewed and underwent a general physical examination, blood tests and ultrasonography of the gallbladder a...

journal_title：Age and ageing

authors： Montalto G,Soresi M,Carroccio A,Averna MR,Muratore R,Li Castri C,Barbagallo CM,Cavera G,Sapienza M,Notarbartolo A

更新日期：1992-09-01 00:00:00

abstract：:Orthostatic hypotension is a common problem in older adults and can be associated with falls, dizziness and syncope and their associated consequences. Therefore, it is important to recognise the condition and institute appropriate management. We report an elderly woman who presented with orthostatic hypotension and wa...

journal_title：Age and ageing

authors： Bragg F,Kumar NP

更新日期：2005-05-01 00:00:00

abstract：:Hospital-at-Home schemes have been claimed to hasten the discharge of elderly orthopaedic patients, and are becoming increasingly popular with health service managers. In an attempt to measure the benefits of such a scheme when applied to elderly medical patients, we prospectively randomized 60 consecutive referrals o...

journal_title：Age and ageing

authors： Donald IP,Baldwin RN,Bannerjee M

更新日期：1995-09-01 00:00:00

abstract：Introduction:identifying the most at risk older people in Emergency Departments (EDs) may help guide clinical practice, and service improvement in emergency care, but little is known about how to implement such tools in practice. Methods:consensus building was used to determine the desirable characteristics of a risk ...

journal_title：Age and ageing

authors： Elliott A,Phelps K,Regen E,Conroy SP

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Previous research has indicated that age-related medical or health conditions can affect driving performance in older adults but little, if any, research has examined the mechanisms through which health conditions affect driving difficulties in older adults. DESIGN:Cross-sectional, correlational study. SET...

journal_title：Age and ageing

authors： Tuokko HA,Rhodes RE,Dean R

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Obtaining well-founded estimates of the effect of demographic change on future health expenditures is a pressing issue in all developed countries. Thus far, expenditure projections have examined the effect of age on health care costs, but fail to account for the influence of remaining life expectancy on cost...

journal_title：Age and ageing

authors： Seshamani M,Gray A

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:to investigate auditory function in subjects with early Alzheimer's disease, mild cognitive impairment and with subjective memory complaints, in search of signs of central auditory processing dysfunction even in early stages of cognitive impairment. DESIGN AND SUBJECTS:a consecutive group of men and women, r...

journal_title：Age and ageing

authors： Idrizbegovic E,Hederstierna C,Dahlquist M,Kämpfe Nordström C,Jelic V,Rosenhall U

更新日期：2011-03-01 00:00:00