Abstract:
OBJECTIVE:to explore the relationship between blood lipids/lipoproteins and cognitive function in the Chinese oldest-old. DESIGN:multivariate statistical analysis using cross-sectional data. SETTING:community-based setting in longevity areas in China. SUBJECTS:eight hundred and thirty-six subjects aged 80 and older were included in the sample. METHODS:plasma total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood pressure and fasting plasma glucose were measured and information about demographics and lifestyle was collected. Cognitive status was assessed using the Mini-Mental State Examination (MMSE). RESULTS:cumulative logit model analysis showed that triglyceride was significantly negatively associated with cognitive impairment. By general linear modelling, there was a significant linear trend of MMSE scores with the level of triglyceride, but not with levels of cholesterol after adjustment. The odds ratio (OR) of cognitive impairment (MMSE score < 18) was significantly reduced for the highest quartile of plasma triglyceride concentration (OR: 0.52, 95% CI: 0.33-0.84), but not for the second or third quartile, compared with the lowest quartile (adjusted models). There were no significant associations between cognitive impairment and cholesterol. CONCLUSION:we concluded that high normal plasma triglyceride was associated with preservation of cognitive function while lower concentrations were not in the Chinese oldest-old.
journal_name
Age Ageingjournal_title
Age and ageingauthors
Yin ZX,Shi XM,Kraus VB,Fitzgerald SM,Qian HZ,Xu JW,Zhai Y,Sereny MD,Zeng Ydoi
10.1093/ageing/afs033subject
Has Abstractpub_date
2012-09-01 00:00:00pages
600-6issue
5eissn
0002-0729issn
1468-2834pii
afs033journal_volume
41pub_type
杂志文章相关文献
AGE AND AGEING文献大全abstract::Brucellosis is the most commonly reported zoonosis. Nervous system participation can occur at any stage of the disease either in acute or subacute or chronic form. Isolated nervous system involvement or neurobrucellosis is a relatively rare form of the disease. We describe an unusual case of an older patient with deme...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afz020
更新日期:2019-07-01 00:00:00
abstract::A retrospective study was performed of 163 patients aged 65 years and over with a diagnosis of duodenal ulceration admitted to one Health District over a period of six years. Eighty per cent of the patients were admitted with acute complications, 50% bled and 30% were perforated. A large proportion of these patients w...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/14.4.225
更新日期:1985-07-01 00:00:00
abstract:BACKGROUND:several studies examining diet and functional status of individuals have focused on single nutrients or food groups. Studies examining the relationship between diet and health have increasingly witnessed a shift in focus from single nutrients to overall diet quality. The objective of this study was to examin...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afr158
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:the recognition of stroke symptoms by the public and activation of the emergency medical services (EMS) are the most important factors in instigating pre-hospital stroke care. Studies have suggested that poor recognition of the warning signs of stroke is the main cause of delay in accessing the EMS. METHODS...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afp196
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:faecal incontinence affects quality of life and causes caregiver strain. Patients are often reluctant to seek help because of embarrassment and perceived lack of effective treatment. Persisting faecal soiling may lead to unwanted and premature institutionalization. OBJECTIVE:to ascertain the prevalence of f...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/30.6.503
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:arterial stiffening is a marker of vascular ageing and an independent risk factor for cardiovascular disease. A potential mechanism linking cardiovascular disease to chronic kidney disease might be the change in arterial elasticity. We aim to determine the association between renal function and arterial stif...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu111
更新日期:2014-11-01 00:00:00
abstract::Inappropriate prescribing (IP) is a common and serious global healthcare problem in elderly people, leading to increased risk of adverse drug reactions (ADRs), polypharmacy being the main risk factor for both IP and ADRs. IP in older people is highly prevalent but preventable; hence screening tools for IP have been de...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afm189
更新日期:2008-03-01 00:00:00
abstract::Spasticity is common after stroke and other neurological conditions and causes considerable limitations of movement, activities of daily living and participation. Interaction with other components of the upper motor neurone syndrome (UMNS) and the heterogeneity of patients' presentations together with limited tools fo...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/aft064
更新日期:2013-07-01 00:00:00
abstract::Explicit criteria, such as the STOPP/START criteria, are increasingly used both in clinical practice and in research to identify potentially inappropriate prescribing in older people. In an article on the STOPP/START criteria version 2, O'Mahony et al have pointed out the advantages of developing computerised criteria...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw114
更新日期:2016-09-01 00:00:00
abstract::The cardiovascular responses to tilting and breathing were studied in 24 patients with late-onset Alzheimer's disease (AD) and 54 healthy control women aged between 75 and 96 years in order to study the parasympathetic and sympathetic heart-rate control. The cardiovascular response to tilting and breathing showed no a...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/21.4.301
更新日期:1992-07-01 00:00:00
abstract::A study of 414 elderly residents of sheltered accommodation in West Essex investigated the degree to which health, physical handicap and support from community care services affected dental needs and utilization of dental services. The study population had a mean age of 77 years, 77% lived alone, 17% were housebound a...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/17.2.103
更新日期:1988-03-01 00:00:00
abstract:Objective:To establish a consensus on the care and professional development needs of registered nurses (RNs) employed by UK care homes. Design:Two-stage, online modified Delphi study. Setting and Participants:A panel (n = 352) of individuals with experience, expertise or interest in care home nursing: (i) care home n...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afw160
更新日期:2017-01-08 00:00:00
abstract:BACKGROUND:In older ambulatory persons, exercise strategies that are expected to generate beneficial muscle adaptations with low cardiopulmonary demands are needed. OBJECTIVE:We hypothesised that eccentric resistance exercise would be less demanding on the cardiovascular and pulmonary systems than bouts of concentric ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afj082
更新日期:2006-05-01 00:00:00
abstract::Recent studies have shown a defect in the cholinergic system of the cerebral cortex of patients suffering from nonvascular senile dementia. This observation suggests the possibility of instituting some kind of replacement therapy and trial have been carried out. At this juncture it seem pertinent to ask what lessons c...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/8.2.86
更新日期:1979-05-01 00:00:00
abstract:BACKGROUND:there is a suggestion that while the age-adjusted incidence of hip fracture in the West may be declining, the incidence may be rising in Asia. OBJECTIVE:this study examines the incidence and post-fracture mortality from 2001 to 2009 among the population aged 65 years and over. METHODS:hip fracture incidenc...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afs177
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:in recent years, the NHS has been accused of ageism frequently and from many fronts. Previous studies have shown that the number of critical care beds in the UK is inadequate to meet the needs of the population. This study asks whether there is discrimination against older people in access to these critical ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/32.4.382
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVES:the absolute number of notifications for tuberculosis in older people appears to have increased in Scotland. To determine if these trends are present elsewhere in the UK, we have reviewed notifications in Leeds with particular reference to non-pulmonary disease, Asian subcontinent groups and older people. M...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/29.4.319
更新日期:2000-07-01 00:00:00
abstract::Clinical observations suggest an age-associated decline in skin perfusion but there are few quantitative in vivo data on skin perfusion at various ages. We studied skin perfusion of the dorsum of the foot by determining the capillary blood flow velocity (CBFV) expressed in millivolts (mV), using laser Doppler flowmetr...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/21.4.237
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVES:we investigated the exact relationship between age and gender on augmentation pressure (AG) and augmentation index (AI) measured over the radial (muscular) and carotid (elastic) arteries. DESIGN AND METHODS:AG is the contribution that wave reflection makes to systolic arterial pressure. AI is an indirect me...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afl115
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:home visits and telephone calls are two often used approaches in transitional care, but their differential economic effects are unknown. OBJECTIVE:to examine the differential economic benefits of home visits with telephone calls and telephone calls only in transitional discharge support. DESIGN:cost-effect...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/afu166
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The very old are expected to become a growing part of the stroke population in the industrialised part of the world. The aims of this study were to evaluate clinical characteristics of patients aged 85 years or more at stroke onset and to investigate very old age as an independent predictor of sh...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afh052
更新日期:2004-03-01 00:00:00
abstract::The overactive bladder is the commonest underlying bladder disorder causing urinary incontinence in elderly people. Management of the condition relies upon a holistic assessment of the problem, lifestyle adjustment, behavioural management and drug therapy. The majority of currently available drugs rely on their anti-m...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/31.4.241
更新日期:2002-07-01 00:00:00
abstract:Objective:to describe differences in care and 30-day mortality of patients admitted with hip fracture on weekends (Saturday-Sunday) compared to weekdays (Monday-Friday), and their relationship to the organisation of care. Methods:data came from the National Hip Fracture Database (NHFD) linked to ONS mortality data on ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afy074
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:nasogastric tube (NGT) feeding is commonly used after stroke, but its effectiveness is limited by frequent dislodgement. OBJECTIVE:the objective of the study was to evaluate looped NGT feeding in acute stroke patients with dysphagia. METHODS:this was a randomised controlled trial of 104 patients with acute...
journal_title:Age and ageing
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/ageing/afq088
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:The reason why elderly human hips tend to break in one of two anatomical regions is uncertain. Nutritional factors may affect the site of fracture. OBJECTIVE:To assess possible nutritional differences in patients with proximal femoral fractures. DESIGN:Prospective observational cohort study. SETTING:Unive...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/28.5.458
更新日期:1999-09-01 00:00:00
abstract:CASE REPORTS:We report three cases of rectus sheath haematoma in elderly women. This condition is commonly misdiagnosed at any age but is an even more elusive diagnosis in elderly patients. CONCLUSION:It is important to consider rectus sheath haematoma in older patients with an abdominal or pelvic mass or spontaneous ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/27.4.512
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:Using Newcastle 85+ Study data, we investigated transitions between frailty states from age 85 to 90 years and whether multi-morbidities and socioeconomic status (SES) modify transitions. METHODS:The Newcastle 85+ Study is a prospective, longitudinal cohort study of all people born in 1921 in Newcastle and ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afaa054
更新日期:2020-10-23 00:00:00
abstract:BACKGROUND:dysphagia is common in acute stroke. Accurate detection of the presence or absence of aspiration by bedside swallowing assessment is difficult without objective methods, tending to over-diagnose aspiration. As a result, some patients suffer restricted oral intake unnecessarily. OBJECTIVE:we examined the pre...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/29.6.495
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:in 2007, the National Patient Safety Agency (NPSA) published 'Slips trips and falls in hospital' and 'Using bedrails safely and effectively'. OBJECTIVES:this observational study aimed to identify changes in local policies in hospitals in England and Wales following these publications. METHOD:policies in pl...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afs063
更新日期:2013-01-01 00:00:00
abstract::Deprescribing has gained interest recently, driven by an ageing population seeing an increasing number living with multiple long-term conditions. This, coupled with disease-specific guidelines derived from clinical trials in younger people, has led to an increase in exposure to polypharmacy and the associated therapeu...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afz109
更新日期:2019-11-01 00:00:00