Central auditory function in early Alzheimer's disease and in mild cognitive impairment.

abstract：BACKGROUND:in 2007, the National Patient Safety Agency (NPSA) published 'Slips trips and falls in hospital' and 'Using bedrails safely and effectively'. OBJECTIVES:this observational study aimed to identify changes in local policies in hospitals in England and Wales following these publications. METHOD:policies in pl...

journal_title：Age and ageing

authors： Healey F,Treml J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:the human body composition changes with advances in age. Particularly, the central fat amount increases. Because the central fat mass is a cardiovascular risk factor, we investigated whether in an elderly population, fat mass (measured at different bodily locations) is associated with peripheral and central ...

journal_title：Age and ageing

authors： van Dijk S,van den Meiracker A,van der Cammen T,Mattace Raso F,van der Velde N

更新日期：2012-07-01 00:00:00

abstract：Background:making informed decisions about cancer care provision for older cancer patients can be challenging and complex. Evidence suggests cancer care varies by age, however the relationship between age and care experiences from diagnosis to death for cancer patients within the UK has not previously been examined in ...

journal_title：Age and ageing

authors： Craigs CL,Bennett MI,Hurlow A,West RM,Ziegler LE

更新日期：2018-11-01 00:00:00

abstract：Objective:to investigate a high-intensity functional exercise (HIFE) group in hospitalised older adults. Design:assessor-blinded, randomised-controlled trial. Setting:sub-acute wards at a metropolitan rehabilitation hospital. Participants:older adults ≥65 years (n = 468) able to stand with minimum assistance or less...

journal_title：Age and ageing

authors： Raymond MJ,Jeffs KJ,Winter A,Soh SE,Hunter P,Holland AE

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:home visits and telephone calls are two often used approaches in transitional care, but their differential economic effects are unknown. OBJECTIVE:to examine the differential economic benefits of home visits with telephone calls and telephone calls only in transitional discharge support. DESIGN:cost-effect...

journal_title：Age and ageing

authors： Wong FK,So C,Chau J,Law AK,Tam SK,McGhee S

更新日期：2015-01-01 00:00:00

abstract：:Clinical assessments have to be used in epidemiological studies in the absence of more objective means of establishing diagnosis or recording events in the natural history of disease. This requires the standardization of definition, technique and interpretation as a means of reducing observer variability in clinical e...

journal_title：Age and ageing

authors： Garraway WM,Akhtar AJ,Gore SM,Prescott RJ,Smith RG

更新日期：1976-11-01 00:00:00

abstract：:Sporadic Creutzfeld-Jakob disease (CJD) is a rare neurodegenerative disorder. It is uniformly fatal. Clinical signs include myoclonus, visual disturbances, cerebellar ataxia, akinetic mutism and pyramidal/extrapyramidal signs in addition to a rapidly progressive dementia. Premortem diagnosis is challenging due to the ...

journal_title：Age and ageing

authors： Podger H,Ipe A

更新日期：2020-04-27 00:00:00

abstract：BACKGROUND:cranberry juice is often given to older people in hospital to prevent urinary tract infection (UTI), although there is little evidence to support its use. OBJECTIVE:to assess whether cranberry juice ingestion is effective in reducing UTIs in older people in hospital. DESIGN:randomised, placebo-controlled, ...

journal_title：Age and ageing

authors： McMurdo ME,Bissett LY,Price RJ,Phillips G,Crombie IK

更新日期：2005-05-01 00:00:00

abstract：INTRODUCTION:Patients with Parkinson's disease (PD) are not routinely prescribed bone-protecting medication despite the fact that they are known to be at risk of falling. We investigated whether subjects with PD were more at risk of fractures than other patient groups in order to establish whether preventative measures...

journal_title：Age and ageing

authors： Genever RW,Downes TW,Medcalf P

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. OBJECTIVE:to investigate the association of education with the onset of terminal decline in g...

journal_title：Age and ageing

authors： Terrera GM,Minett T,Brayne C,Matthews FE

更新日期：2014-01-01 00:00:00

abstract：:The type of environmental hazards implicated in the aetiology of a consecutive series of 787 hip-fracture patients was prospectively studied. Most falls occurred between 09 h 00 and midday and there was no seasonal variation. Fifty-one different environmental hazards were implicated in the aetiology of the fall for 58...

journal_title：Age and ageing

authors： Parker MJ,Twemlow TR,Pryor GA

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:to evaluate the effectiveness of a multifactorial intervention on incidence of falls in psychogeriatric nursing home patients. DESIGN:cluster-randomised controlled 12-month trial. SETTING:psychogeriatric wards in 12 nursing homes in The Netherlands. PARTICIPANTS:psychogeriatric nursing home patients (n = 5...

journal_title：Age and ageing

authors： Neyens JC,Dijcks BP,Twisk J,Schols JM,van Haastregt JC,van den Heuvel WJ,de Witte LP

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:faecal incontinence affects quality of life and causes caregiver strain. Patients are often reluctant to seek help because of embarrassment and perceived lack of effective treatment. Persisting faecal soiling may lead to unwanted and premature institutionalization. OBJECTIVE:to ascertain the prevalence of f...

journal_title：Age and ageing

authors： Edwards NI,Jones D

更新日期：2001-11-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs are currently being investigated as agents to reduce the incidence and progression of Alzheimer's disease. Paradoxically they have also been reported to induce deleterious effects on the central nervous system, including aseptic meningitis and cognitive decline in the elderly. We ...

journal_title：Age and ageing

authors： Ashton D,Kim P,Griffiths N,Beran R

更新日期：2004-07-01 00:00:00

abstract：:Twenty digitalized elderly patients with chronic atrial fibrillation were randomized into a double-blind cross-over study. None was in overt heart failure and all were taking < 80 mg frusemide daily. They received xamoterol 200 mg b.d. for 2 months with their usual dose of digoxin for 1 month and placebo digoxin for t...

journal_title：Age and ageing

authors： Lawson-Matthew PJ,McLean KA,Dent M,Austin CA,Channer KS

更新日期：1995-07-01 00:00:00

abstract：:In a study of two representative population samples of 70-year-olds, one of which was followed up at 75 years of age, digitalis treatment was associated with oestrogen-like metabolic effects, indicated by changes in the composition of the plasma phospholipid fraction. Digitalis treatment, at least at these ages, is re...

journal_title：Age and ageing

authors： Persson G,Landahl S,Svanborg A

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:Age is thought to be strongly associated with intensive care outcomes, but this relationship may be confounded by many clinical variables. OBJECTIVES:To compare clinical characteristics of elderly patients (> or = 65 years) admitted to the intensive care unit (ICU) with those in younger patients and to iden...

journal_title：Age and ageing

authors： Vosylius S,Sipylaite J,Ivaskevicius J

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVES:To compare costs and outcome of occupational therapy-led assessment with social worker-led assessment of older people, in terms of their independence and quality of life. DESIGN:Cost-effectiveness analysis alongside a randomised controlled trial. The analysis took viewpoints of health services and patients....

journal_title：Age and ageing

authors： Flood C,Mugford M,Stewart S,Harvey I,Poland F,Lloyd-Smith W

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Frailty was shown to be associated with psychosocial risk factors, but there are few longitudinal data. METHODS:We used data from waves 5 and 6 of the Survey of Health Aging Retirement in Europe (SHARE) to study the contribution of loneliness and social isolation to transitions towards frailty defined accor...

journal_title：Age and ageing

authors： Jarach CM,Tettamanti M,Nobili A,D'avanzo B

更新日期：2021-01-08 00:00:00

abstract：BACKGROUND:There is a paucity of information about the use of antipsychotic medication in long-term care, especially among the oldest-old residents. OBJECTIVE:To analyse the factors associated with the use of antipsychotic medication among nonagenarian residents in long-term institutional care. DESIGN:A retrospective...

journal_title：Age and ageing

authors： Alanen HM,Finne-Soveri H,Noro A,Leinonen E

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Therapists and nurses often use verbal instruction in the rehabilitation of mobility following stroke. This study aimed to determine whether performing a verbal cognitive task while walking adversely affected patients' balance and velocity. METHODS:There were two counterbalanced conditions: walking only and...

journal_title：Age and ageing

authors： Bowen A,Wenman R,Mickelborough J,Foster J,Hill E,Tallis R

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The long-term effectiveness of group continence promotion delivered via community organisations on female urinary incontinence, falls and healthy life expectancy remains unknown. METHODS:A pragmatic cluster randomised trial was conducted among 909 women aged 65-98 years with urinary incontinence, recruited ...

journal_title：Age and ageing

authors： Tannenbaum C,Fritel X,Halme A,van den Heuvel E,Jutai J,Wagg A

更新日期：2019-07-01 00:00:00

abstract：:Bone's mechanical competence and its fragility in particular depend to a certain extent on the structure and microstructure of the cortical bone compartment. Beyond bone mineral density (BMD) and bone mineral content, a variety of other features of cortical bone contribute to whole bone's resistance to fracture. Struc...

journal_title：Age and ageing

authors： Augat P,Schorlemmer S

更新日期：2006-09-01 00:00:00

abstract：Introduction:identifying the most at risk older people in Emergency Departments (EDs) may help guide clinical practice, and service improvement in emergency care, but little is known about how to implement such tools in practice. Methods:consensus building was used to determine the desirable characteristics of a risk ...

journal_title：Age and ageing

authors： Elliott A,Phelps K,Regen E,Conroy SP

更新日期：2017-09-01 00:00:00

abstract：AIM:to examine the degree of medical treatment wanted by nursing home residents, their relatives and staff members should the resident develop a serious and life-threatening disease and to analyse the degree of agreement between the wishes of these parties. DESIGN:an epidemiological, descriptive cross-sectional study....

journal_title：Age and ageing

authors： Moe C,Schroll M

更新日期：1997-03-01 00:00:00

abstract：:Vaginal pessaries are widely considered to be a safe alternative to surgery in older women. We report a case of near fatal septicaemia in a 75-year-old woman associated with a shelf pessary, the presence of which was identified during an exploratory laparotomy. This case highlights the importance of the gynaecological...

journal_title：Age and ageing

authors： Wheeler LD,Lazarus R,Torkington J,O'Mahony MS,Woodhouse KW

更新日期：2004-09-01 00:00:00

abstract：INTRODUCTION:Age limits for diagnostics and treatments have been largely removed and replaced by an active diagnostic and treatment practice among the oldest old and has led to concerns about potential overtreatment during the last years of life. METHODS:Use of prescription medication in the last years of life was ass...

journal_title：Age and ageing

authors： Pedersen JK,Jensen TM,Waldorff FB,Søndergaard J,Christensen K

更新日期：2020-10-23 00:00:00

abstract：OBJECTIVE:to ascertain the value of employing a specialist clinician's contribution to the assessment of older people prior to care home entry. DESIGN:randomised controlled trial. METHOD:256 older people at risk of care home entry were randomly allocated to either a control group, who received the usual care manageme...

journal_title：Age and ageing

authors： Challis D,Clarkson P,Williamson J,Hughes J,Venables D,Burns A,Weinberg A

更新日期：2004-01-01 00:00:00

abstract：:This study describes a survey of 256 informal carers and elderly people they support, and examines the impact of the caring role upon quality of life. Carers reported that many aspects of their physical and mental health as well as their social and family lives were affected by their caring. For many the caring activi...

journal_title：Age and ageing

authors： Jones DA,Peters TJ

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To examine how improved attention to nutritional status and dietary intake, achieved through the employment of dietetic assistants (DAs), will affect postoperative clinical outcome among elderly women with hip fracture. DESIGN:Open prospective randomised controlled trial, comparing conventional nursing care ...

journal_title：Age and ageing

authors： Duncan DG,Beck SJ,Hood K,Johansen A

更新日期：2006-03-01 00:00:00