Bilateral facial palsy in an older person.

abstract：BACKGROUND:Multi-morbidity and polypharmacy increase the risk of non-trivial adverse drug reactions (ADRs) in older people during hospitalization. Despite this, there are no established interventions for hospital-acquired ADR prevention. METHODS:We undertook a pragmatic, multi-national, parallel arm prospective random...

journal_title：Age and ageing

authors： O'Mahony D,Gudmundsson A,Soiza RL,Petrovic M,Jose Cruz-Jentoft A,Cherubini A,Fordham R,Byrne S,Dahly D,Gallagher P,Lavan A,Curtin D,Dalton K,Cullinan S,Flanagan E,Shiely F,Samuelsson O,Sverrisdottir A,Subbarayan S,V

更新日期：2020-07-01 00:00:00

abstract：:The DOMINO study compared domiciliary and hospital-based rehabilitation services for stroke patients after discharge from hospital, stratified by the hospital ward at discharge. No difference between the services had been found at 6 months, but home therapy was better than outpatient department therapy at improving ho...

journal_title：Age and ageing

authors： Gladman JR,Lincoln NB

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:exposures in childhood and adolescence may impact the development of diseases and symptoms in late life. However, evidence from low- and middle-income countries is scarce. In this cross-sectional study, we examined the association of early life risk factors with frailty amongst older adults using a large, na...

journal_title：Age and ageing

authors： Li Y,Xue QL,Odden MC,Chen X,Wu C

更新日期：2020-02-27 00:00:00

abstract：Introduction:frailty is an increased vulnerability to adverse health outcomes, across multiple physiological systems, with both environmental and genetic drivers. The two most commonly used measures are Rockwood's frailty index (FI) and Fried's frailty phenotype (FP). Material and methods:the present study included 36...

journal_title：Age and ageing

authors： Livshits G,Ni Lochlainn M,Malkin I,Bowyer R,Verdi S,Steves CJ,Williams FMK

更新日期：2018-01-01 00:00:00

abstract：:In one experiment, four groups of six-week-old-male PVG rats were, respectively, given tap water ('control group'), 0.00125M, 0.0025M, and 0.005M lathyrogen (aminoacetonitrile hydrochloride: AAN) solutions ad libitum for a period of 20 weeks. In a second experiment, 12-week-old male rats were similarly treated. It was...

journal_title：Age and ageing

authors： Morgan AJ,Bellamy D

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:fifteen percent of patients with Crohn's disease (CD) are elderly; they are less likely to have complications and more likely to have colonic disease. OBJECTIVE:to compare disease behaviour in patients with CD based on age at diagnosis. DESIGN:cross-sectional study. SETTING:tertiary referral centre. SUBJ...

journal_title：Age and ageing

authors： Quezada SM,Steinberger EK,Cross RK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:physical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death. METHODS:in the Women's Health Initiativ...

journal_title：Age and ageing

authors： Saquib N,Brunner R,Desai M,Kroenke C,Martin LW,Daviglus M,Allen NB,Robinson J,Tindle H,Stefanick ML

更新日期：2019-05-01 00:00:00

abstract：:Fifty-eight carers and their dependents who received inpatient respite care were studied before and during the admission period. Although there was no observable improvement in the carers' emotional well-being the majority of the patients showed an improvement in functioning, particularly those who were being looked a...

journal_title：Age and ageing

authors： Homer AC,Gilleard CJ

更新日期：1994-07-01 00:00:00

abstract：:In this study we examine whether the introduction of a clerking pro forma improves the completeness of the recording of the management of stroke patients and we review methodological issues important in this type of audit. We prospectively identified 244 consecutive stroke patients before and after the introduction of...

journal_title：Age and ageing

authors： Davenport RJ,Dennis MS,Warlow CP

更新日期：1995-01-01 00:00:00

abstract：:We present two cases of acute hepatotoxicity associated with elevated paracetamol (acetaminophen) levels in older patients. Both patients were receiving a standard European dose of oral paracetamol (2 × 500 mg QDS) with no risk factors for slowed metabolism (weight <50 kg, interacting medications, hepatic enzyme induc...

journal_title：Age and ageing

authors： Ging P,Mikulich O,O'Reilly KM

更新日期：2016-07-01 00:00:00

abstract：:Seventy-nine patients with probable Alzheimer's disease were enrolled into a double-blind, placebo-controlled cross-over study to assess the therapeutic effect and safety of THA (tetrahydroaminoacridine; tacrine) without concomitant lecithin administration. Forty-one patients completed the trial which consisted of two...

journal_title：Age and ageing

authors： Wilcock GK,Surmon DJ,Scott M,Boyle M,Mulligan K,Neubauer KA,O'Neill D,Royston VH

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:The long-term effectiveness of group continence promotion delivered via community organisations on female urinary incontinence, falls and healthy life expectancy remains unknown. METHODS:A pragmatic cluster randomised trial was conducted among 909 women aged 65-98 years with urinary incontinence, recruited ...

journal_title：Age and ageing

authors： Tannenbaum C,Fritel X,Halme A,van den Heuvel E,Jutai J,Wagg A

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:delirium is a frequent complication of hospital admission for older people and can be reduced by multicomponent interventions, but implementation and delivery of such interventions is challenging. OBJECTIVE:to investigate fidelity to the prevention of delirium system of care within a multicentre, pragmatic,...

journal_title：Age and ageing

authors： Smith J,Green J,Siddiqi N,Inouye SK,Collinson M,Farrin A,Young J

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:the purpose of this study was to evaluate the likelihood that the presence of certain medical conditions in older ambulatory patients are associated with the risk of developing a new pressure ulcer. DESIGN:a cohort study. SETTING AND SUBJECTS:a large outpatient record database from the United Kingdom calle...

journal_title：Age and ageing

authors： Margolis DJ,Knauss J,Bilker W,Baumgarten M

更新日期：2003-05-01 00:00:00

abstract：:The cardiovascular responses to tilting and breathing were studied in 24 patients with late-onset Alzheimer's disease (AD) and 54 healthy control women aged between 75 and 96 years in order to study the parasympathetic and sympathetic heart-rate control. The cardiovascular response to tilting and breathing showed no a...

journal_title：Age and ageing

authors： Elmståhl S,Petersson M,Lilja B,Samuelsson SM,Rosén I,Bjunö L

更新日期：1992-07-01 00:00:00

abstract：:The aim of this study was to evaluate the type and frequency of falls presenting to an inner city casualty department, and to identify modifiable risk factors in these patients. A prospective descriptive study evaluated those over 65 years presenting to an inner city casualty department with falls. Over a 4-week recru...

journal_title：Age and ageing

authors： Davies AJ,Kenny RA

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:health-related quality of life (HRQOL) is an important psycho-social characteristic which may impact an individual's ability to manage their chronic disease. We examined the association between HRQOL and antihypertensive medication adherence in older adults. METHODS:participants were part of a cohort study of ...

journal_title：Age and ageing

authors： Holt EW,Muntner P,Joyce CJ,Webber L,Krousel-Wood MA

更新日期：2010-07-01 00:00:00

abstract：AIM:to determine the positive yield of carotid sinus massage in different patient groups: unexplained syncope, falls, dizziness and controls. DESIGN:observational study. SETTING:teaching hospital. METHODS:we studied consecutive patients over the age of 60 years referred to the 'falls clinic' with a history of unexpl...

journal_title：Age and ageing

authors： Kumar NP,Thomas A,Mudd P,Morris RO,Masud T

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Hypertension is a risk factor for both cardiovascular and cerebrovascular disease, with an increasing incidence with advancing patient age. Exercise interventions have the potential to reduce blood pressure in older adults, however, rates of exercise uptake and adherence are low, with 'lack of time' a common...

journal_title：Age and ageing

authors： Herrod PJJ,Lund JN,Phillips BE

更新日期：2020-10-17 00:00:00

abstract：INTRODUCTION:care home residents have high healthcare needs not fully met by prevailing healthcare models. This study explored how healthcare configuration influences resource use. METHODS:a realist evaluation using qualitative and quantitative data from case studies of three UK health and social care economies select...

journal_title：Age and ageing

authors： Gordon AL,Goodman C,Davies SL,Dening T,Gage H,Meyer J,Schneider J,Bell B,Jordan J,Martin FC,Iliffe S,Bowman C,Gladman JRF,Victor C,Mayrhofer A,Handley M,Zubair M

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVES:To determine the presentation, course and duration of delirium in hospitalized older people. DESIGN:Observational cohort study. SETTING:Inpatient surgical and medical wards at a university hospital. PARTICIPANTS:432 people over the age of 65. MEASUREMENTS:All participants were screened daily for confusio...

journal_title：Age and ageing

authors： Rudberg MA,Pompei P,Foreman MD,Ross RE,Cassel CK

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:two common anti-diabetic treatments used are sitagliptin and sulphonylureas however evidence examining their comparative effectiveness in older people is limited. OBJECTIVE:to evaluate effectiveness of sitagliptin vs sulphonylureas when added to metformin in older (aged ≥75) vs younger people (18-75). DESI...

journal_title：Age and ageing

authors： Sharma M,Nazareth I,Petersen I

更新日期：2019-09-01 00:00:00

abstract：:Prolonged head-up tilt is increasingly used as a diagnostic test for vasovagal syncope. Its sensitivity is reported to increase with the concurrent administration of intravenous isoprenaline. False-positive responses are common in young controls particularly following intravascular instrumentation. We studied the infl...

journal_title：Age and ageing

authors： McIntosh SJ,Lawson J,Kenny RA

更新日期：1994-07-01 00:00:00

abstract：:A retrospective study was performed of 163 patients aged 65 years and over with a diagnosis of duodenal ulceration admitted to one Health District over a period of six years. Eighty per cent of the patients were admitted with acute complications, 50% bled and 30% were perforated. A large proportion of these patients w...

journal_title：Age and ageing

authors： Watson RJ,Hooper TL,Ingram G

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to (i) survey the risk factors for NSAID gastropathy in outpatients (elderly patients in the community), compared to those living in old people's homes or nursing homes, (ii) study the prescription of medication prophylaxis during use of NSAIDs conform the current national g...

journal_title：Age and ageing

authors： van Leen MW,van der Eijk I,Schols JM

更新日期：2007-07-01 00:00:00

abstract：Background:despite an increasing proportion of older people working beyond State Pension Age (SPA), little is known about neither the motivations for this decision nor whether, and to what extent, working beyond SPA affects quality of life (QoL). Methods:QoL was measured using the CASP-19 scale. Respondents in paid wo...

journal_title：Age and ageing

authors： Di Gessa G,Corna L,Price D,Glaser K

更新日期：2018-05-01 00:00:00

abstract：Background:there is limited data comparing conditions and health service use across care settings in centenarians. To improve health service delivery in centenarians, the aim of this study was to compare the proportion of centenarians who have chronic conditions, take medication and use health care services across diff...

journal_title：Age and ageing

authors： von Berenberg P,Dräger D,Zahn T,Neuwirth J,Kuhlmey A,Gellert P

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:this study aimed to investigate the construct validity and responsiveness of performance-based and self-reported measures of strength, mobility and balance after hip fracture. DESIGN:secondary analysis of clinical trial data. SUBJECTS:a total of 148 older people undergoing hip fracture rehabilitation. MET...

journal_title：Age and ageing

authors： Farag I,Sherrington C,Kamper SJ,Ferreira M,Moseley AM,Lord SR,Cameron ID

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:despite the vast literature in the area, few studies examined the large range of factors associated with physical activity (PA) in the older adult collectively, information that could help develop a supportive culture for healthy ageing. OBJECTIVE:to identify the socio-demographic, social connectedness, phy...

journal_title：Age and ageing

authors： McKee G,Kearney PM,Kenny RA

更新日期：2015-07-01 00:00:00

abstract：Background:high cardiorespiratory fitness (CRF) is associated with larger brain volumes but data on sex differences in the association of CRF with brain volumes are scarce. We investigated whether the association of CRF with total grey matter (GM) and white matter volumes as well as medial temporal lobe and striatum vo...

journal_title：Age and ageing

authors： Pentikäinen H,Ngandu T,Liu Y,Savonen K,Komulainen P,Hallikainen M,Kivipelto M,Rauramaa R,Soininen H

更新日期：2017-03-01 00:00:00