Is medication use by community-dwelling elderly people influenced by cognitive function?

abstract：:Transcatheter aortic valve implantation (TAVI) is a tremendous therapeutic advance for patients with severe aortic stenosis and high-surgical risk. Since TAVI-treated patients are elderly with multiple co-existing conditions, limited life expectancy and disproportionate health-care expenditures, the aspect of the heal...

journal_title：Age and ageing

authors： Georgiadou P,Sbarouni E,Karavolias GK,Voudris V

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:to describe gender differences in levels of, and longitudinal changes in, habitual physical activity among older people. DESIGN:longitudinal study. PARTICIPANTS:sub-groups of survivors (with sample sizes dependent on the availability of complete datasets, ranging from 303-344) assessed on three occasions: ...

journal_title：Age and ageing

authors： Bennett KM

更新日期：1998-12-01 00:00:00

abstract：:In a study of two representative population samples of 70-year-olds, one of which was followed up at 75 years of age, digitalis treatment was associated with oestrogen-like metabolic effects, indicated by changes in the composition of the plasma phospholipid fraction. Digitalis treatment, at least at these ages, is re...

journal_title：Age and ageing

authors： Persson G,Landahl S,Svanborg A

更新日期：1982-11-01 00:00:00

abstract：:The disproportionately high suicide rate among the elderly is examined in this review. As opposed to younger age groups, a close association exists between suicide and parasuicide in old age. Factors associated with these events include a high incidence of depression, serious physical illness, as well as social factor...

journal_title：Age and ageing

authors： Shulman K

更新日期：1978-11-01 00:00:00

abstract：:The measurement of cutaneous pain threshold using the Neuromod Selectra Model 7750 Transcutaneous Neuronal Electrical Stimulator is described. Pain threshold, measured in 520 healthy volunteers aged 5-105 years, increased with age. Consistent values were obtained in 22 healthy volunteers on three successive days. Pain...

journal_title：Age and ageing

authors： Tucker MA,Andrew MF,Ogle SJ,Davison JG

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Valproate (VPA) is an antiepileptic drug with a broad spectrum of efficacy. Although usually well-tolerated, it may have side-effects of which encephalopathy is one of the most serious. OBJECTIVE:To describe the clinical characteristics of valproate encephalopathy (VE) in five older patients with remote sym...

journal_title：Age and ageing

authors： Beyenburg S,Back C,Diederich N,Lewis M,Reuber M

更新日期：2007-05-01 00:00:00

abstract：:Fasting serum cholesterol and triglyceride levels, and lipoprotein electrophoretic patterns have been investigated in 42 men aged 67-92 years (mean 79 years). Although all the cholesterol and the majority of the triglyceride levels were within the normal range for younger people, both were significantly greater (P < 0...

journal_title：Age and ageing

authors： Horsey J,Livesley B,Dickerson JW

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:there is a suggestion that while the age-adjusted incidence of hip fracture in the West may be declining, the incidence may be rising in Asia. OBJECTIVE:this study examines the incidence and post-fracture mortality from 2001 to 2009 among the population aged 65 years and over. METHODS:hip fracture incidenc...

journal_title：Age and ageing

authors： Chau PH,Wong M,Lee A,Ling M,Woo J

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:frailty is a dynamic condition for which a range of interventions are available. Health state utilities are values that represent the strength of an individual's preference for specific health states, and are used in economic evaluation. This is a topic yet to be examined in detail for frailty. Likewise, lit...

journal_title：Age and ageing

authors： Thompson MQ,Theou O,Ratcliffe J,Tucker GR,Adams RJ,Walters SJ,Visvanathan R

更新日期：2020-09-16 00:00:00

abstract：BACKGROUND:arterial stiffening is a marker of vascular ageing and an independent risk factor for cardiovascular disease. A potential mechanism linking cardiovascular disease to chronic kidney disease might be the change in arterial elasticity. We aim to determine the association between renal function and arterial stif...

journal_title：Age and ageing

authors： Sedaghat S,Dawkins Arce FG,Verwoert GC,Hofman A,Ikram MA,Franco OH,Dehghan A,Witteman JC,Mattace-Raso F

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Studies have shown strong associations between disability, social support and depressive symptoms in older people; but socio-economic effects are less clear and little is known about the role of health locus of control. OBJECTIVE:To examine the roles of physical health, disability, social support, socio-eco...

journal_title：Age and ageing

authors： Harris T,Cook DG,Victor C,Rink E,Mann AH,Shah S,DeWilde S,Beighton C

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:to assess the validity of the Direct Assessment of Functional Status (DAFS) performance-based functional scale for the staging of dementia severity by comparing it with established clinical, functional and cognitive scales. PATIENTS AND METHODS:93 consecutive Alzheimer's disease patients underwent DAFS. Soci...

journal_title：Age and ageing

authors： Zanetti O,Frisoni GB,Rozzini L,Bianchetti A,Trabucchi M

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:prevalence estimates for chronic diseases and associated risk factors are needed for priority setting and disease prevention strategies. The aim of this cross-sectional study was to estimate the self-reported and clinical prevalence of common chronic disorders in elderly men. STUDY DESIGN AND SETTING:a quest...

journal_title：Age and ageing

authors： Frost M,Wraae K,Gudex C,Nielsen T,Brixen K,Hagen C,Andersen M

更新日期：2012-03-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) isolated from patients with Alzheimer's disease to produce interleukin-1 and -2 (IL-1, IL-2) was compared to that of cells from age-matched controls and young healthy subjects. There was no difference in the production of both interleukins between patients and ...

journal_title：Age and ageing

authors： Bessler H,Sirota P,Hart J,Djaldetti M

更新日期：1989-01-01 00:00:00

abstract：:Digoxin elimination phase kinetics have been studied in 24 hospital in-patients (mean age 79 years), six of whom showed no evidence of digoxin toxicity. The others, with suspected toxicity, have been grouped according to the nature of the drug effects observed. Renal function, digoxin elimination half-life, apparent v...

journal_title：Age and ageing

authors： Reid J,Kennedy RD,Caird FI

更新日期：1983-02-01 00:00:00

abstract：:Bone's mechanical competence and its fragility in particular depend to a certain extent on the structure and microstructure of the cortical bone compartment. Beyond bone mineral density (BMD) and bone mineral content, a variety of other features of cortical bone contribute to whole bone's resistance to fracture. Struc...

journal_title：Age and ageing

authors： Augat P,Schorlemmer S

更新日期：2006-09-01 00:00:00

abstract：:Integrated care programs have been developed to enhance the quality care for older adults in primary care. These programs usually consist of a multidisciplinary approach, with personalised care based on comprehensive geriatric assessments. However, there is limited evidence for the effectiveness of these programs in f...

journal_title：Age and ageing

authors： Hoogendijk EO

更新日期：2016-09-01 00:00:00

abstract：:The clinical diagnosis of Parkinson's disease may be difficult. In elderly patients there may be other causes of the triad of rigidity, bradykinesia and tremor. This study was designed to assess whether a single levodopa challenge could predict dopa responsiveness in patients with Parkinson's disease. Twenty-two of 27...

journal_title：Age and ageing

authors： D'Costa DF,Sheehan LJ,Phillips PA,Moore-Smith B

更新日期：1995-05-01 00:00:00

abstract：:Lower urinary tract symptoms are frequency report in Parkinson's disease. Whether these are causally related to Parkinson's disease rather than the known effects of age on the urinary tract is unknown. In this study we compared urodynamic data from 1864 women and 357 men with no neurological disease with data from 34 ...

journal_title：Age and ageing

authors： Gray R,Stern G,Malone-Lee J

更新日期：1995-11-01 00:00:00

abstract：UNLABELLED:Delirium is one of the foremost unmet medical needs in healthcare. It affects one in eight hospitalised patients and is associated with multiple adverse outcomes including increased length of stay, new institutionalisation, and considerable patient distress. Recent studies also show that delirium strongly pr...

journal_title：Age and ageing

authors： Maclullich AM,Anand A,Davis DH,Jackson T,Barugh AJ,Hall RJ,Ferguson KJ,Meagher DJ,Cunningham C

更新日期：2013-11-01 00:00:00

abstract：:A study is reported of the religious beliefs, attitudes, and practice of old people in the West of Scotland, based on a questionnaire given to 501 people aged 65 years and over randomly selected from those living at home. Almost all had had a full range of religious instruction, and regarded their parents as religious...

journal_title：Age and ageing

authors： Reid WS,Gilmore AJ,Andrews GR,Caird FI

更新日期：1978-02-01 00:00:00

abstract：:Doppler-shifted ultrasound and spectral analysis were used to assess signals from the resting supra-orbital artery and the common carotid artery at the base of the neck of 658 (270 male, 388 female) asymptomatic subjects aged 5 to 90 years. The sonagrams obtained showed two peaks (A and B) during cardiac systole. The ...

journal_title：Age and ageing

authors： Baskett JJ,Lewis RR,Beasley MG,Gosling RG

更新日期：1985-03-01 00:00:00

abstract：:A study was carried out to examine the prevalence of oropharyngeal and urinary tract colonization and to compare the colonizing bacteria with the strains causing nosocomial infections during patients' stays in a geriatric ward. Colonization with Gram-negative rods was not uncommon. Nosocomial infections frequently occ...

journal_title：Age and ageing

authors： Michielsen W,Vandevondele D,Verschraegen G,Claeys G,Afschrift M

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:to examine the relationships between impairments in hearing and vision and mortality from all-causes and cardiovascular disease (CVD) among older people. DESIGN:population-based cohort study. PARTICIPANTS:the study population included 4,926 Icelandic individuals, aged ≥67 years, 43.4% male, who completed vi...

journal_title：Age and ageing

authors： Fisher D,Li CM,Chiu MS,Themann CL,Petersen H,Jónasson F,Jónsson PV,Sverrisdottir JE,Garcia M,Harris TB,Launer LJ,Eiriksdottir G,Gudnason V,Hoffman HJ,Cotch MF

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The Timed Up and Go Test (TUGT) has been recommended as a simple screening tool to identify those at risk of falling. However, subsequent detailed assessment is required to identify underlying falls risk factors to provide direction for optimal targeted intervention strategies. METHODS:110 consecutive falls...

journal_title：Age and ageing

authors： Whitney JC,Lord SR,Close JC

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. OBJECTIVE:to investigate the association of education with the onset of terminal decline in g...

journal_title：Age and ageing

authors： Terrera GM,Minett T,Brayne C,Matthews FE

更新日期：2014-01-01 00:00:00

abstract：:The contribution of the elderly to the workload of a combined consultative District Hospital Gastroenterology Clinic has been studied over a 12-year period. The elderly group comprise 24% of the total referrals with a gradually increasing trend over successive years. The service implications are discussed and the main...

journal_title：Age and ageing

authors： Purkayastha SK,Salter RH,Holmes KM

更新日期：1988-01-01 00:00:00

abstract：:This study aimed to determine the prevalence of the wish to die in elderly people and investigate the factors associated with it, in particular, whether factors other than depression contribute to the wish to die. Data were obtained from an Australian epidemiological survey of people aged 70 or more. Survey participan...

journal_title：Age and ageing

authors： Jorm AF,Henderson AS,Scott R,Korten AE,Christensen H,Mackinnon AJ

更新日期：1995-09-01 00:00:00

abstract：Background/Objective:studies on the association of dementia with specific body composition (BC) components are scarce. Our aim was to investigate associations of BC measures with different levels of cognitive function in late-life. Methods:we studied 5,169 participants (mean age 76 years, 42.9% men) in the AGES-Reykja...

journal_title：Age and ageing

authors： Spauwen PJ,Murphy RA,Jónsson PV,Sigurdsson S,Garcia ME,Eiriksdottir G,van Boxtel MP,Lopez OL,Gudnason V,Harris TB,Launer LJ

更新日期：2017-03-01 00:00:00

abstract：:Energy intake and resting energy expenditure in relation to body composition were studied in female patients with Alzheimer's disease, multi-infarct dementia and in home-living non-demented elderly women. Patients with Alzheimer's disease tended to have lower body weight and higher energy intake (p = NS) than control ...

journal_title：Age and ageing

authors： Niskanen L,Piirainen M,Koljonen M,Uusitupa M

更新日期：1993-03-01 00:00:00