A double-blind comparison of quinine sulphate and placebo in muscle cramps.

Abstract:

:Muscle cramps are painful and common in elderly patients but have largely escaped medical investigation. Quinine sulphate is usually the sole drug prescribed, even though firm evidence for its efficacy is not available. The results of the present double-blind cross-over study show that quinine was significantly superior to placebo in decreasing the number, severity and duration of nocturnal cramps. Since quinine is not a primary drug in any other condition, further studies of drugs with similar pharmacological actions may thus improve our management of this painful complaint.

journal_name

Age Ageing

journal_title

Age and ageing

authors

Jones K,Castleden CM

doi

10.1093/ageing/12.2.155

subject

Has Abstract

pub_date

1983-05-01 00:00:00

pages

155-8

issue

2

eissn

0002-0729

issn

1468-2834

journal_volume

12

pub_type

临床试验,杂志文章,随机对照试验
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    doi:10.1093/ageing/afu111

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  • Recovery in instrumental activities of daily living (IADLs): findings from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS).

    abstract:OBJECTIVE:to provide evidence for predictors of recovery in instrumental activities of daily living (IADLs) among disabled older people living in the community. DESIGN:MRC CFAS recruited a sample of 13,004 individuals aged 65 years and above from five communities in the UK. Participants underwent a baseline interview ...

    journal_title:Age and ageing

    pub_type: 杂志文章,多中心研究

    doi:10.1093/ageing/afp128

    authors: Seidel D,Jagger C,Brayne C,Matthews FE,Cfas M

    更新日期:2009-11-01 00:00:00

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    abstract:METHOD:We investigated the association of total serum cholesterol concentrations and subsequent overall and coronary mortality in 304 patients aged > or =65 discharged from hospital after acute myocardial infarction. RESULTS:There was no association between total cholesterol concentrations and mortality due to either ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/28.3.313

    authors: Bo M,Fiandra U,Fonte G,Bobbio M,Fabris F

    更新日期:1999-05-01 00:00:00

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/27.2.199

    authors: Higgs PF,MacDonald LD,MacDonald JS,Ward MC

    更新日期:1998-03-01 00:00:00

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/9.4.241

    authors: Bates CJ,Fleming M,Paul AA,Black AE,Mandal AR

    更新日期:1980-11-01 00:00:00

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afz109

    authors: Woodford HJ,Fisher J

    更新日期:2019-11-01 00:00:00

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afaa051

    authors: Quilot E,Petit JM,Vergès B,Bouillet B

    更新日期:2020-08-24 00:00:00

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/19.1.19

    authors: Lincoln NB,Edmans JA

    更新日期:1990-01-01 00:00:00

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    journal_title:Age and ageing

    pub_type: 杂志文章,评审

    doi:10.1093/ageing/aft064

    authors: Graham LA

    更新日期:2013-07-01 00:00:00

  • Review: xerostomia: a symptom which acts like a disease.

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    pub_type: 杂志文章,评审

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    更新日期:1996-09-01 00:00:00

  • Secrets and lies: the dilemma of disclosing the diagnosis to an adult with dementia.

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/32.4.439

    authors: Fahy M,Wald C,Walker Z,Livingston G

    更新日期:2003-07-01 00:00:00

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    journal_title:Age and ageing

    pub_type: 杂志文章,评审

    doi:10.1093/ageing/22.1.65

    authors: McCreadie C,Tinker A

    更新日期:1993-01-01 00:00:00

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    pub_type: 杂志文章,评审

    doi:10.1093/ageing/afl077

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    更新日期:2006-09-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1093/ageing/32.1.60

    authors: Tousignant M,Hébert R,Dubuc N,Simoneau F,Dieleman L

    更新日期:2003-01-01 00:00:00

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    pub_type: 杂志文章,评审

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    authors: Augat P,Schorlemmer S

    更新日期:2006-09-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1093/ageing/afy094

    authors: Craigs CL,Bennett MI,Hurlow A,West RM,Ziegler LE

    更新日期:2018-11-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1093/ageing/21.6.421

    authors: Jones DA,Peters TJ

    更新日期:1992-11-01 00:00:00

  • A prediction model for one- and three-year mortality in dementia: results from a nationwide hospital-based cohort of 50,993 patients in the Netherlands.

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afaa007

    authors: van de Vorst IE,Golüke NMS,Vaartjes I,Bots ML,Koek HL

    更新日期:2020-04-27 00:00:00

  • Gender and longitudinal changes in physical activities in later life.

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    journal_title:Age and ageing

    pub_type: 杂志文章

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    authors: Bennett KM

    更新日期:1998-12-01 00:00:00

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    journal_title:Age and ageing

    pub_type: 杂志文章

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    authors: Espaulella J,Arnau A,Cubí D,Amblàs J,Yánez A

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    pub_type: 杂志文章

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afaa234

    authors: Chow L

    更新日期:2021-01-08 00:00:00

  • Smoking cessation in late life is associated with increased risk of all-cause mortality amongst oldest old people: a community-based prospective cohort study.

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    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afaa280

    authors: Wei Y,Lv Y,Zhou J,Gao X,Duan J,Zhao C,Yin Z,Kang Q,Wu B,Chen C,Mao C,Li J,Shi X

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    journal_title:Age and ageing

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    journal_title:Age and ageing

    pub_type: 杂志文章,评审

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    journal_title:Age and ageing

    pub_type: 杂志文章,随机对照试验

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