Abstract:
OBJECTIVE:To determine the association between functional and nutritional changes caused by an acute illness requiring hospitalisation and 6-month mortality. DESIGN:Hospital-based prospective longitudinal cohort study. SETTING:Acute care centre (Hospital General de Vic, Barcelona Province, Spain). Post-acute care centre (Hospital de la Santa Creu de Vic, Barcelona Province, Spain). SUBJECTS:Hundred sixty five patients aged 75 years and older, hospitalised for an acute event. METHODS:Functional status (Barthel and Lawton Indices), cognitive status (Short Portable Mental Status Questionnaire), nutritional status (Mini Nutritional Assessment, albumin, cholesterol), depressive symptoms (Geriatric Depression Scale), co-morbidity (Charlson Index) and self-rated health status were collected upon admission to the post-acute care centre. Functional and nutritional status were assessed 1, 3 and 6 months after admission by a trained staff of geriatricians. Six-month mortality was the main outcome variable. Survival analysis was performed with functional and nutritional status as time-dependent variables. RESULTS:The mean age of the cohort was 83.3 years (SD 5.1) and 68.5% were female. Six-month mortality was 29.1% (95% CI: 22.2-36.7). The variables associated with mortality in bivariate analysis were: gender, Barthel Index (2 weeks before admission), Lawton Index (2 weeks before admission), Charlson Index, Barthel Index (time-dependent), Mini Nutritional Assessment (MNA) (time-dependent) and cognitive status. The variables associated with mortality in multivariate analysis were: gender, Barthel Index (2 weeks before admission), Charlson Index and MNA (time-dependent). CONCLUSIONS:Functional and nutritional changes due to an acute illness have a statistical and clinical prognostic value and should be assessed along with other well-known relevant prognostic factors.
journal_name
Age Ageingjournal_title
Age and ageingauthors
Espaulella J,Arnau A,Cubí D,Amblàs J,Yánez Adoi
10.1093/ageing/afm033subject
Has Abstractpub_date
2007-07-01 00:00:00pages
407-13issue
4eissn
0002-0729issn
1468-2834pii
afm033journal_volume
36pub_type
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