Warfarin sensitivity: be aware of genetic influence.

abstract：OBJECTIVE:to ascertain the value of employing a specialist clinician's contribution to the assessment of older people prior to care home entry. DESIGN:randomised controlled trial. METHOD:256 older people at risk of care home entry were randomly allocated to either a control group, who received the usual care manageme...

journal_title：Age and ageing

authors： Challis D,Clarkson P,Williamson J,Hughes J,Venables D,Burns A,Weinberg A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:frequent emergency department (ED) attendance at the end of life disrupts care continuity and contradicts most patients' preference for home-based care. OBJECTIVE:to examine factors associated with frequent (≥3) end of life ED attendances among older people to identify opportunities to improve care. METHOD...

journal_title：Age and ageing

authors： Bone AE,Evans CJ,Henson LA,Gao W,Higginson IJ,BUILDCARE study.

更新日期：2019-09-01 00:00:00

abstract：:Formal assessment of cognitive decline with cognitive tests can be difficult, requiring either two measurement points or a comparison of 'hold' with 'don't hold' tests. Informant-based assessment provides an alternative approach because informants can adopt a longitudinal perspective and directly rate cognitive change...

journal_title：Age and ageing

authors： Jorm AF,Christensen H,Henderson AS,Jacomb PA,Korten AE,Mackinnon A

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:two common anti-diabetic treatments used are sitagliptin and sulphonylureas however evidence examining their comparative effectiveness in older people is limited. OBJECTIVE:to evaluate effectiveness of sitagliptin vs sulphonylureas when added to metformin in older (aged ≥75) vs younger people (18-75). DESI...

journal_title：Age and ageing

authors： Sharma M,Nazareth I,Petersen I

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:the aim of this study was to compare the effects of a functional tasks exercise programme to a cognitive training programme in older adults with mild cognitive impairment. DESIGN:a single-blind randomised control trial with the intervention group compared with an active control group. SETTING:out-patient cl...

journal_title：Age and ageing

authors： Law LL,Barnett F,Yau MK,Gray MA

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:nasogastric tube (NGT) feeding is commonly used after stroke, but its effectiveness is limited by frequent dislodgement. OBJECTIVE:the objective of the study was to evaluate looped NGT feeding in acute stroke patients with dysphagia. METHODS:this was a randomised controlled trial of 104 patients with acute...

journal_title：Age and ageing

authors： Beavan J,Conroy SP,Harwood R,Gladman JR,Leonardi-Bee J,Sach T,Bowling T,Sunman W,Gaynor C

更新日期：2010-09-01 00:00:00

abstract：:The change in mental and physical functioning over 5 years for 594 survivors of a community survey of the elderly is described. An increase in cognitive impairment, physical disability and incontinence over the period was found with increasing age. Women in the two oldest age groups had a significantly greater increas...

journal_title：Age and ageing

authors： Jagger C,Clarke M,Cook AJ

更新日期：1989-03-01 00:00:00

abstract：Background:measuring the complex needs of care home residents is crucial for resource allocation. Hospital patient administration systems (PAS) may not accurately identify admissions from care homes. Objective:to develop and validate an accurate, practical method of identifying care home resident hospital admission us...

journal_title：Age and ageing

authors： Housley G,Lewis S,Usman A,Gordon AL,Shaw DE

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:to determine the safety and effect of intravenous iron sucrose on functional outcomes, delirium, nosocomial infections and transfusion requirements in older patients with hip fracture. DESIGN:single-centre randomised, double-blind, placebo-controlled clinical trial. SETTING AND PARTICIPANTS:orthogeriatric ...

journal_title：Age and ageing

authors： Bielza R,Llorente J,Thuissard IJ,Andreu-Vázquez C,Blanco D,Sanjurjo J,López N,Herráez MR,Molano C,Morales A,Arias E,Neira M,Lung A,Escalera J,Portillo L,Larrubia Y,García C,Zambrana F,Gómez Cerezo J

更新日期：2021-01-08 00:00:00

abstract：OBJECTIVES:The purpose of this paper is to investigate the utilisation of general practice Medicare Benefit Schedule (MBS) services aligned to Comprehensive Geriatric Assessment (CGA) within 6 months of an aged care eligibility assessment and its effects on mortality and transition to permanent residential aged care (P...

journal_title：Age and ageing

authors： Visvanathan R,Amare AT,Wesselingh S,Inacio MC

更新日期：2020-12-23 00:00:00

abstract：OBJECTIVES:the purpose of this study was to evaluate the likelihood that the presence of certain medical conditions in older ambulatory patients are associated with the risk of developing a new pressure ulcer. DESIGN:a cohort study. SETTING AND SUBJECTS:a large outpatient record database from the United Kingdom calle...

journal_title：Age and ageing

authors： Margolis DJ,Knauss J,Bilker W,Baumgarten M

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:an abbreviated form of the Duke Social Support Index (DSSI) as used in a large longitudinal study of older Australian women was examined with respect to factors that might be expected to affect social support for older women over time. METHODS:in this large cohort study two sub-scales of the DSSI, one descri...

journal_title：Age and ageing

authors： Pachana NA,Smith N,Watson M,McLaughlin D,Dobson A

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Patients with Parkinson's disease (PD) are not routinely prescribed bone-protecting medication despite the fact that they are known to be at risk of falling. We investigated whether subjects with PD were more at risk of fractures than other patient groups in order to establish whether preventative measures...

journal_title：Age and ageing

authors： Genever RW,Downes TW,Medcalf P

更新日期：2005-01-01 00:00:00

abstract：:The relationship between hip fractures and aluminium in antacids and cooking pots was examined in an epidemiological study in Sydney, Australia. A population-based case-control study was conducted and 416 men and women aged 65 years and over were recruited (209 cases and 207 controls). There was a significantly (p < 0...

journal_title：Age and ageing

authors： Cumming RG,Klineberg RJ

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Delirium is a common neuropsychiatric disorder. The natural course is of an acute, fluctuating and often transient condition; however, accumulating evidence suggests that delirium can be associated with incomplete recovery. Despite a growing body of research, a lack of clarity exists regarding definition and...

journal_title：Age and ageing

authors： Adamis D,Devaney A,Shanahan E,McCarthy G,Meagher D

更新日期：2015-03-01 00:00:00

abstract：:Recent studies have shown a defect in the cholinergic system of the cerebral cortex of patients suffering from nonvascular senile dementia. This observation suggests the possibility of instituting some kind of replacement therapy and trial have been carried out. At this juncture it seem pertinent to ask what lessons c...

journal_title：Age and ageing

authors： Kendall MJ

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:in recent years, the NHS has been accused of ageism frequently and from many fronts. Previous studies have shown that the number of critical care beds in the UK is inadequate to meet the needs of the population. This study asks whether there is discrimination against older people in access to these critical ...

journal_title：Age and ageing

authors： Hubbard RE,Lyons RA,Woodhouse KW,Hillier SL,Wareham K,Ferguson B,Major E

更新日期：2003-07-01 00:00:00

abstract：:Drug compliance was assessed amongst all 91 patients attending a psychogeriatric day hospital during July 1988. Of the 86 patients taking medication, the 57 functionally and 29 organically ill patients were interviewed at home, the latter with their carers. A disparity in results was shown when compliance was measured...

journal_title：Age and ageing

authors： Rosenvinge HP,Groarke EP,Bradshaw JW

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:despite the vast literature in the area, few studies examined the large range of factors associated with physical activity (PA) in the older adult collectively, information that could help develop a supportive culture for healthy ageing. OBJECTIVE:to identify the socio-demographic, social connectedness, phy...

journal_title：Age and ageing

authors： McKee G,Kearney PM,Kenny RA

更新日期：2015-07-01 00:00:00

abstract：:In a study of two representative population samples of 70-year-olds, one of which was followed up at 75 years of age, digitalis treatment was associated with oestrogen-like metabolic effects, indicated by changes in the composition of the plasma phospholipid fraction. Digitalis treatment, at least at these ages, is re...

journal_title：Age and ageing

authors： Persson G,Landahl S,Svanborg A

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:to evaluate the effectiveness of a multifactorial intervention on incidence of falls in psychogeriatric nursing home patients. DESIGN:cluster-randomised controlled 12-month trial. SETTING:psychogeriatric wards in 12 nursing homes in The Netherlands. PARTICIPANTS:psychogeriatric nursing home patients (n = 5...

journal_title：Age and ageing

authors： Neyens JC,Dijcks BP,Twisk J,Schols JM,van Haastregt JC,van den Heuvel WJ,de Witte LP

更新日期：2009-03-01 00:00:00

abstract：:Plasma and red-cell folate levels and dietary folate intake were monitored for about six months, including two months during which supplementary vitamin C was given, in 21 healthy elderly men and women living at home in the north of England. Although biochemical values were consistently low in some subjects, no clinic...

journal_title：Age and ageing

authors： Bates CJ,Fleming M,Paul AA,Black AE,Mandal AR

更新日期：1980-11-01 00:00:00

abstract：:Previous studies have suggested that up to a fifth of people over the age of 80 years may suffer severe dementia-like illnesses. This total population survey of over a thousand people over the age of 75 suggests that the prevalence of marked cognitive impairment is much less than expected. However, differences in the ...

journal_title：Age and ageing

authors： Clarke M,Lowry R,Clarke S

更新日期：1986-09-01 00:00:00

abstract：:Interleukin-1 mediates the febrile response which is often said to be reduced in the elderly. Interleukin-1 production by monocytes cultured in vitro and stimulated with bacterial lipopolysaccharide was measured. Three groups of subjects were studied; 40 normal young, 33 well elderly and 40 elderly with a history of r...

journal_title：Age and ageing

authors： Rudd AG,Banerjee DK

更新日期：1989-01-01 00:00:00

abstract：:The measurement of cutaneous pain threshold using the Neuromod Selectra Model 7750 Transcutaneous Neuronal Electrical Stimulator is described. Pain threshold, measured in 520 healthy volunteers aged 5-105 years, increased with age. Consistent values were obtained in 22 healthy volunteers on three successive days. Pain...

journal_title：Age and ageing

authors： Tucker MA,Andrew MF,Ogle SJ,Davison JG

更新日期：1989-07-01 00:00:00

abstract：Background:making informed decisions about cancer care provision for older cancer patients can be challenging and complex. Evidence suggests cancer care varies by age, however the relationship between age and care experiences from diagnosis to death for cancer patients within the UK has not previously been examined in ...

journal_title：Age and ageing

authors： Craigs CL,Bennett MI,Hurlow A,West RM,Ziegler LE

更新日期：2018-11-01 00:00:00

abstract：:The Neuberger report failed to show that the Liverpool Care Pathway was the cause of poor end-of-life care and made it the scapegoat for poor communication and faulty decision-making. The report's discrediting of a quality assurance mechanism that had the potential for improvement is a disservice to dying patients. Se...

journal_title：Age and ageing

authors： Regnard C

更新日期：2014-03-01 00:00:00

abstract：:Of 1042 individuals aged 65 years and over who were successfully interviewed in a community survey of health and physical activity, 35% (n = 356) reported one or more falls in the preceding year. Although the overall ratio of female fallers to male fallers was 2.7:1, this ratio approached unity with advancing age. Mob...

journal_title：Age and ageing

authors： Blake AJ,Morgan K,Bendall MJ,Dallosso H,Ebrahim SB,Arie TH,Fentem PH,Bassey EJ

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:the Falls Risk for Older People in the Community assessment (FROP-Com) tool was designed for use in targeted multi-factorial falls prevention programmes. It fills the gap between the short screening tools and the longer assessment tools, e.g. the physiological profile assessment (PPA). The aim of this study ...

journal_title：Age and ageing

authors： Russell MA,Hill KD,Blackberry I,Day LM,Dharmage SC

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:The electronic Frailty Index (eFI) has been developed in primary care settings. The Hospital Frailty Risk Score (HFRS) was derived using secondary care data. OBJECTIVE:Compare the two different tools for identifying frailty in older people admitted to hospital. DESIGN AND SETTING:Retrospective cohort study...

journal_title：Age and ageing

authors： Hollinghurst J,Housley G,Watkins A,Clegg A,Gilbert T,Conroy SP

更新日期：2020-11-30 00:00:00