Abstract:
:Interleukin-1 mediates the febrile response which is often said to be reduced in the elderly. Interleukin-1 production by monocytes cultured in vitro and stimulated with bacterial lipopolysaccharide was measured. Three groups of subjects were studied; 40 normal young, 33 well elderly and 40 elderly with a history of repeated infection. No difference in interleukin-1 secretion was found between the groups. When the group with recurrent infection was subdivided into those with a history of fever and those with no record of fever accompanying their infection, the group without fever produced significantly less interleukin-1 (p = 0.035).
journal_name
Age Ageingjournal_title
Age and ageingauthors
Rudd AG,Banerjee DKdoi
10.1093/ageing/18.1.43subject
Has Abstractpub_date
1989-01-01 00:00:00pages
43-6issue
1eissn
0002-0729issn
1468-2834journal_volume
18pub_type
杂志文章相关文献
AGE AND AGEING文献大全abstract::Integrated care programs have been developed to enhance the quality care for older adults in primary care. These programs usually consist of a multidisciplinary approach, with personalised care based on comprehensive geriatric assessments. However, there is limited evidence for the effectiveness of these programs in f...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afw081
更新日期:2016-09-01 00:00:00
abstract::The aim of this prospective study was to investigate whether an immunological double faecal occult blood test (Fecatwin-S/FECA-EIA) can be used in screening patients with symptoms suggestive of colonic or rectal origin in primary health care. Altogether 523 patients were referred to the study by general practitioners....
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/23.5.365
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:dementia is associated with an excess risk of death but mortality after chronic subdural hematoma (CSDH) evacuation in older people with dementia is unknown. We assessed the association between dementia and 1-year case-fatality in older persons undergoing CSDH evacuation. METHODS:we conducted a nationwide F...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afaa193
更新日期:2020-10-06 00:00:00
abstract:Background:making informed decisions about cancer care provision for older cancer patients can be challenging and complex. Evidence suggests cancer care varies by age, however the relationship between age and care experiences from diagnosis to death for cancer patients within the UK has not previously been examined in ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afy094
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:in recent years, the NHS has been accused of ageism frequently and from many fronts. Previous studies have shown that the number of critical care beds in the UK is inadequate to meet the needs of the population. This study asks whether there is discrimination against older people in access to these critical ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/32.4.382
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:a large number of studies have explored factors related to self- and informant ratings of quality of life in people with dementia, but many studies have had relatively small sample sizes and mainly focused on health conditions and dementia symptoms. The aim of this study is to compare self- and informant-rat...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afz177
更新日期:2020-04-27 00:00:00
abstract:BACKGROUND:Delirium is a common neuropsychiatric disorder. The natural course is of an acute, fluctuating and often transient condition; however, accumulating evidence suggests that delirium can be associated with incomplete recovery. Despite a growing body of research, a lack of clarity exists regarding definition and...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afu152
更新日期:2015-03-01 00:00:00
abstract::The type of environmental hazards implicated in the aetiology of a consecutive series of 787 hip-fracture patients was prospectively studied. Most falls occurred between 09 h 00 and midday and there was no seasonal variation. Fifty-one different environmental hazards were implicated in the aetiology of the fall for 58...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/25.4.322
更新日期:1996-07-01 00:00:00
abstract::In one experiment, four groups of six-week-old-male PVG rats were, respectively, given tap water ('control group'), 0.00125M, 0.0025M, and 0.005M lathyrogen (aminoacetonitrile hydrochloride: AAN) solutions ad libitum for a period of 20 weeks. In a second experiment, 12-week-old male rats were similarly treated. It was...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/5.3.155
更新日期:1976-08-01 00:00:00
abstract::The measurement of cutaneous pain threshold using the Neuromod Selectra Model 7750 Transcutaneous Neuronal Electrical Stimulator is described. Pain threshold, measured in 520 healthy volunteers aged 5-105 years, increased with age. Consistent values were obtained in 22 healthy volunteers on three successive days. Pain...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/18.4.241
更新日期:1989-07-01 00:00:00
abstract::Ejection fraction was measured directly by a radionuclide method, and indirectly from systolic time intervals, in elderly patients in atrial fibrillation. Both methods show that the ejection fraction averages approximately 55% at mean ventricular rates of 50-70 beats/min and falls to 20% or below as mean rate increase...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/10.4.231
更新日期:1981-11-01 00:00:00
abstract:BACKGROUND:Vitamin D deficiency is common in older people and may increase risk of falls and fracture. Hospital inpatients are at particular risk of falling. Previous studies suggest that vitamin D improves neuromuscular function and reduces falls. OBJECTIVE:To determine whether routine supplementation with vitamin D ...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/afm087
更新日期:2007-09-01 00:00:00
abstract::In the period 1967-1981, 102 patients older than 70 years were treated for a colorectal carcinoma. The mean age was 76 years. The average delay was 7.6 months. Obstruction as initial symptom was seen in only 8% of the cases. The resection rate was 85%. The postoperative mortality rate was 6% for patients patients who ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/14.6.321
更新日期:1985-11-01 00:00:00
abstract::Sleep disordered breathing (SDB) may be associated with cognitive dysfunction in non-demented elderly people. A random sample of 96 retirement village residents were given both neuropsychological assessment and overnight sleep monitoring with a portable microprocessor based system (Vitalog PMS-8). Respiratory disturba...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/21.2.121
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND:The risk/benefit ratio of warfarin therapy changes in the over 75s, when haemorrhagic side-effects become more common. These may not always be reported in the literature. CASE REPORT:A woman of 80 years, on long-term warfarin therapy presented with an acute dissecting thoracic aortic aneurysm; on investigat...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afh015
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:The electronic Frailty Index (eFI) has been developed in primary care settings. The Hospital Frailty Risk Score (HFRS) was derived using secondary care data. OBJECTIVE:Compare the two different tools for identifying frailty in older people admitted to hospital. DESIGN AND SETTING:Retrospective cohort study...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afaa252
更新日期:2020-11-30 00:00:00
abstract:OBJECTIVE:to provide evidence for predictors of recovery in instrumental activities of daily living (IADLs) among disabled older people living in the community. DESIGN:MRC CFAS recruited a sample of 13,004 individuals aged 65 years and above from five communities in the UK. Participants underwent a baseline interview ...
journal_title:Age and ageing
pub_type: 杂志文章,多中心研究
doi:10.1093/ageing/afp128
更新日期:2009-11-01 00:00:00
abstract::We measured calcium regulating hormones and bone mineral density (BMD) in 66 men (aged 24-88 years). Vitamin D (1,25(OH)2D) does not vary with age, parathyroid hormone (PTH) increases after the age of 65 (p < 0.01) together with a parallel increase in urinary (r = 0.46, p < 0.05) and nephrogenic cAMP (r = 0.63, p < 0....
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/23.2.127
更新日期:1994-03-01 00:00:00
abstract::Acute appendicitis in elderly patients has not been studied extensively in the United Kingdom. Studies were performed prior to the regular use of broad spectrum antibiotics and tended to include younger patients. We studied retrospectively all elderly patients (n = 30, mean age = 72 years) who presented in the years 1...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/16.4.256
更新日期:1987-07-01 00:00:00
abstract:INTRODUCTION:Routine cognitive screening for in-patients aged ≥75 years is recommended, but there is uncertainty around how this should be operationalised. We therefore determined the feasibility and reliability of the Abbreviated mental test score (AMTS/10) and its relationship to subjective memory complaint, Montreal...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afv134
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:national reports have highlighted deficiencies in care provided to older surgical patients and suggested a role for innovative, collaborative, inter-specialty models of care. The extent of geriatrician-led perioperative services in the UK (excluding orthogeriatric services) has not previously been describe...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afu084
更新日期:2014-09-01 00:00:00
abstract::The aim of the present study was to determine the prevalence of biliary lithiasis (BL) and its major associated factors in the elderly people of a small town in Sicily. All inhabitants over the age of 65 were interviewed and underwent a general physical examination, blood tests and ultrasonography of the gallbladder a...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/21.5.338
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:Age is thought to be strongly associated with intensive care outcomes, but this relationship may be confounded by many clinical variables. OBJECTIVES:To compare clinical characteristics of elderly patients (> or = 65 years) admitted to the intensive care unit (ICU) with those in younger patients and to iden...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afi037
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:to explore views on advance care planning in care homes for older people. DESIGN:qualitative exploration of views from care home staff and the family of residents in care homes for older people. SETTING:all care homes for the elderly in two London Boroughs. PARTICIPANTS:staff (care managers, nurses and car...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afr006
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:the aim of this study was to compare the effects of a functional tasks exercise programme to a cognitive training programme in older adults with mild cognitive impairment. DESIGN:a single-blind randomised control trial with the intervention group compared with an active control group. SETTING:out-patient cl...
journal_title:Age and ageing
pub_type: 杂志文章,随机对照试验
doi:10.1093/ageing/afu055
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:to review systematically the range of case definitions and methods used to measure falls in randomised controlled trials. DESIGN/METHODS:a Cochrane review of fall prevention interventions was used to identify fall definitions in published trials. Secondary searches of various databases were used to identify ...
journal_title:Age and ageing
pub_type: 杂志文章,评审
doi:10.1093/ageing/afi218
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:to develop a model to predict one- and three-year mortality in patients with dementia attending a hospital, through hospital admission or day/memory clinic. DESIGN:we constructed a cohort of dementia patients through data linkage of three Dutch national registers: the hospital discharge register (HDR), the p...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afaa007
更新日期:2020-04-27 00:00:00
abstract::Cellular immune function declines with age and is implicated in the increased incidence of cancer, and morbidity and mortality associated with infections in elderly people. Elderly people are at risk of nutritional depletion, including of zinc, and zinc is known to influence immunity. The present study assessed zinc s...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/20.5.345
更新日期:1991-09-01 00:00:00
abstract::Seventy-nine patients with probable Alzheimer's disease were enrolled into a double-blind, placebo-controlled cross-over study to assess the therapeutic effect and safety of THA (tetrahydroaminoacridine; tacrine) without concomitant lecithin administration. Forty-one patients completed the trial which consisted of two...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/22.5.316
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:the Falls Risk for Older People in the Community assessment (FROP-Com) tool was designed for use in targeted multi-factorial falls prevention programmes. It fills the gap between the short screening tools and the longer assessment tools, e.g. the physiological profile assessment (PPA). The aim of this study ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/afn129
更新日期:2008-11-01 00:00:00