Evidence of cellular zinc depletion in hospitalized but not in healthy elderly subjects.

abstract：Background:fear of falling (FOF) is a major health concern among community-dwelling older adults that could restrict mobility. Objective:to examine the association of FOF with life-space mobility (i.e. the spatial area a person moves through in daily life) of community-dwelling older adults from five diverse sites. M...

journal_title：Age and ageing

authors： Auais M,Alvarado B,Guerra R,Curcio C,Freeman EE,Ylli A,Guralnik J,Deshpande N

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:the nursing home Resident Assessment Instrument (RAI) includes a set of core assessment items, known as the Minimum Data Set (MDS), for assessment and care screening and more detailed Resident Assessment Protocols in 18 areas that represent common problem areas or risk factors for nursing home residents. Its...

journal_title：Age and ageing

authors： Hawes C,Morris JN,Phillips CD,Fries BE,Murphy K,Mor V

更新日期：1997-09-01 00:00:00

abstract：:This is the second in an occasional series of paired commentaries in Age and Ageing, the Journal of the British Geriatrics Society and the Journal of the American Geriatrics Society (JAGS). The aim is to address issues of current significance and to foster dialogue and increased understanding between academics and cli...

journal_title：Age and ageing

authors： Pollock K,Seymour J

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:ageing is accompanied by impairments in immune responses due to remodelling of the immune system (immunesenescence). Additionally, a decline in habitual physical activity has been reported in older adults. We have recently published that specific features of immunesenescence, such as thymic involution and ...

journal_title：Age and ageing

authors： Bartlett DB,Duggal NA

更新日期：2020-04-27 00:00:00

abstract：PRESENTATION:a previously fit 80-year-old woman presented with a 2-week history of spontaneous and extensive bruising affecting all four limbs. The severity was such that she required a transfusion of 8 units of blood. RESULTS OF INVESTIGATIONS:a markedly prolonged activated partial thromboplastin time which was only ...

journal_title：Age and ageing

authors： Kelly J,Gattens M,Geraghty R

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:there is limited evidence of a protective effect of physical activity in preventing hip fractures among older people living in institutions and in those aged 80 or over. OBJECTIVE:to examine the relationship between physical activity and risk of hip fracture in frail older people. DESIGN:a case-control stu...

journal_title：Age and ageing

authors： Norton R,Galgali G,Campbell AJ,Reid IR,Robinson E,Butler M,Gray H

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:There is a paucity of information about the use of antipsychotic medication in long-term care, especially among the oldest-old residents. OBJECTIVE:To analyse the factors associated with the use of antipsychotic medication among nonagenarian residents in long-term institutional care. DESIGN:A retrospective...

journal_title：Age and ageing

authors： Alanen HM,Finne-Soveri H,Noro A,Leinonen E

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:a large number of studies have explored factors related to self- and informant ratings of quality of life in people with dementia, but many studies have had relatively small sample sizes and mainly focused on health conditions and dementia symptoms. The aim of this study is to compare self- and informant-rat...

journal_title：Age and ageing

authors： Wu YT,Nelis SM,Quinn C,Martyr A,Jones IR,Victor CR,Knapp M,Henderson C,Hindle JV,Jones RW,Kopelman MD,Morris RG,Pickett JA,Rusted JM,Thom JM,Litherland R,Matthews FE,Clare L,IDEAL Programme team.

更新日期：2020-04-27 00:00:00

abstract：BACKGROUND:delirium is under-recognised in comparison to other common and serious acute disorders. A 2006 survey of UK junior doctors (not undertaking specialist training) identified poor knowledge of the diagnostic criteria and treatment of delirium. We hypothesised that increased prominence accorded to delirium in th...

journal_title：Age and ageing

authors： Jenkin RP,Al-Attar A,Richardson S,Myint PK,MacLullich AM,Davis DH

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:in the UK, two-thirds of patients in general hospitals are older than 70, of whom half have dementia or delirium or both. Our objective was to explore doctors, nurses and allied health professionals' perceptions of their preparation to care for confused older patients on general hospital wards....

journal_title：Age and ageing

authors： Griffiths A,Knight A,Harwood R,Gladman JR

更新日期：2014-07-01 00:00:00

abstract：PRESENTATION:an 83-year-old man was admitted to hospital with acute confusion 3 days after a direct flight from Australia. OUTCOME:computed tomography (CT) brain scan and magnetic resonance imaging head scan revealed the cause to be pneumocephalus, apparently the result of barotrauma caused by Valsalva manoeuvres when...

journal_title：Age and ageing

authors： Chan YP,Yau CY,Lewis RR,Kinirons MT

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:intracranial volume (ICV) is commonly used as a marker of premorbid brain size in neuroimaging studies as it is thought to remain fixed throughout adulthood. However, inner skull table thickening would encroach on ICV and could mask actual brain atrophy. OBJECTIVE:we investigated the effect that thickening ...

journal_title：Age and ageing

authors： Aribisala BS,Royle NA,Valdés Hernández MC,Murray C,Penke L,Gow A,Maniega SM,Starr JM,Bastin M,Deary I,Wardlaw J

更新日期：2014-09-01 00:00:00

abstract：:The type of environmental hazards implicated in the aetiology of a consecutive series of 787 hip-fracture patients was prospectively studied. Most falls occurred between 09 h 00 and midday and there was no seasonal variation. Fifty-one different environmental hazards were implicated in the aetiology of the fall for 58...

journal_title：Age and ageing

authors： Parker MJ,Twemlow TR,Pryor GA

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:chronic obstructive pulmonary disease (COPD) prevalence steadily increases with age. However, the effectiveness of inhaled therapy in the elderly COPD population has rarely been formally evaluated. We studied a group of elderly patients with COPD with a range of severity, selected from one General Practice re...

journal_title：Age and ageing

authors： Jarvis S,Ind PW,Shiner RJ

更新日期：2007-03-01 00:00:00

abstract：:The clinical diagnosis of Parkinson's disease may be difficult. In elderly patients there may be other causes of the triad of rigidity, bradykinesia and tremor. This study was designed to assess whether a single levodopa challenge could predict dopa responsiveness in patients with Parkinson's disease. Twenty-two of 27...

journal_title：Age and ageing

authors： D'Costa DF,Sheehan LJ,Phillips PA,Moore-Smith B

更新日期：1995-05-01 00:00:00

abstract：Background:high cardiorespiratory fitness (CRF) is associated with larger brain volumes but data on sex differences in the association of CRF with brain volumes are scarce. We investigated whether the association of CRF with total grey matter (GM) and white matter volumes as well as medial temporal lobe and striatum vo...

journal_title：Age and ageing

authors： Pentikäinen H,Ngandu T,Liu Y,Savonen K,Komulainen P,Hallikainen M,Kivipelto M,Rauramaa R,Soininen H

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:despite the vast literature in the area, few studies examined the large range of factors associated with physical activity (PA) in the older adult collectively, information that could help develop a supportive culture for healthy ageing. OBJECTIVE:to identify the socio-demographic, social connectedness, phy...

journal_title：Age and ageing

authors： McKee G,Kearney PM,Kenny RA

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:to evaluate the effectiveness of a multifactorial intervention on incidence of falls in psychogeriatric nursing home patients. DESIGN:cluster-randomised controlled 12-month trial. SETTING:psychogeriatric wards in 12 nursing homes in The Netherlands. PARTICIPANTS:psychogeriatric nursing home patients (n = 5...

journal_title：Age and ageing

authors： Neyens JC,Dijcks BP,Twisk J,Schols JM,van Haastregt JC,van den Heuvel WJ,de Witte LP

更新日期：2009-03-01 00:00:00

abstract：UNLABELLED:Older people are majority users of health and social care services in the UK and internationally. Many older people who access these services have frailty, which is a state of vulnerability to adverse outcomes. The existing health care response to frailty is mainly secondary care-based and reactive to the ac...

journal_title：Age and ageing

authors： Turner G,Clegg A,British Geriatrics Society.,Age UK.,Royal College of General Practioners.

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:to investigate the effects of oral intermittent cyclical etidronate therapy on bone mineral density (BMD) in men with idiopathic vertebral osteoporosis. DESIGN:consecutive case series. SETTING:regional specialist clinic for metabolic bone disease. SUBJECTS:42 men aged 35-81 (median 60.5) with established ...

journal_title：Age and ageing

authors： Anderson FH,Francis RM,Bishop JC,Rawlings DJ

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:the incidence of pulmonary embolism increases with age but the 'classical' presentation of acute pulmonary embolism may not occur in older persons. OBJECTIVES:to compare the clinical presentation of younger and older patients with acute pulmonary embolism. DESIGN:retrospective identification of 60 consecut...

journal_title：Age and ageing

authors： Timmons S,Kingston M,Hussain M,Kelly H,Liston R

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:self-rated health (SRH) likely reflects both mental and physical health domains, and is assessed by asking individuals to describe their health status. Poor SRH is associated with disease incidence and subsequent mortality. Changes in SRH across time in persons with different incident diseases are uncharacte...

journal_title：Age and ageing

authors： Foraker RE,Rose KM,Chang PP,McNeill AM,Suchindran CM,Selvin E,Rosamond WD

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:fractures are a major health concern among the elderly. People at risk for cardiovascular disease (CVD) are at an increased risk for fractures. The aim of this study was to assess the individual and combined effect of the CVD risk factors of smoking, alcohol consumption and physical activity on fracture risk...

journal_title：Age and ageing

authors： Khatib R,Yusuf S,Barzilay JI,Papaioannou A,Thabane L,Gao P,Joseph PG,Teo K,Mente A

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:dementia is associated with an excess risk of death but mortality after chronic subdural hematoma (CSDH) evacuation in older people with dementia is unknown. We assessed the association between dementia and 1-year case-fatality in older persons undergoing CSDH evacuation. METHODS:we conducted a nationwide F...

journal_title：Age and ageing

authors： Tommiska P,Korja M,Siironen J,Kaprio J,Raj R

更新日期：2020-10-06 00:00:00

abstract：:Recent studies have shown a defect in the cholinergic system of the cerebral cortex of patients suffering from nonvascular senile dementia. This observation suggests the possibility of instituting some kind of replacement therapy and trial have been carried out. At this juncture it seem pertinent to ask what lessons c...

journal_title：Age and ageing

authors： Kendall MJ

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVES:this study investigated the prospective associations of accelerometer assessed daily steps with subsequent depressive symptoms in older adults. METHODS:a 2-year prospective study was performed in the community. A total of 285 older adults ≥65 years (mean age = 74.5) attended the baseline assessment in 2012....

journal_title：Age and ageing

authors： Hsueh MC,Stubbs B,Lai YJ,Sun CK,Chen LJ,Ku PW

更新日期：2020-09-25 00:00:00

abstract：:Ninety-nine residents, 10% of the total population of elderly in Part III accommodation in Newcastle upon Tyne, were examined for the presence of psychiatric disorder, tested for cognitive impairment, and rated for the presence of confusion. Those allocated a diagnosis of dementia were most impaired and confused, and ...

journal_title：Age and ageing

authors： Vardon VM,Blessed G

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Obtaining well-founded estimates of the effect of demographic change on future health expenditures is a pressing issue in all developed countries. Thus far, expenditure projections have examined the effect of age on health care costs, but fail to account for the influence of remaining life expectancy on cost...

journal_title：Age and ageing

authors： Seshamani M,Gray A

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:an abbreviated form of the Duke Social Support Index (DSSI) as used in a large longitudinal study of older Australian women was examined with respect to factors that might be expected to affect social support for older women over time. METHODS:in this large cohort study two sub-scales of the DSSI, one descri...

journal_title：Age and ageing

authors： Pachana NA,Smith N,Watson M,McLaughlin D,Dobson A

更新日期：2008-11-01 00:00:00

abstract：:Genetic factors are known to be of importance in determining the rate of biotransformation of foreign compounds in the liver. Adverse reactions to drugs are increased and pharmacokinetic parameters altered with age. In the present study, the effect of age on plasma paroxonase activity is studied. Paroxonase is a hepat...

journal_title：Age and ageing

authors： Playfer JR,Powell C,Evans DA

更新日期：1977-05-01 00:00:00