Tamoxifen and partial oestrogen agonism in postmenopausal women.

abstract：:Older people attend accident and emergency departments more frequently than younger people. However, most assessments indicate that this higher level of use is appropriate and is the result of more serious injury and illness among this population. Older patients discharged from accident and emergency departments are f...

journal_title：Age and ageing

authors： Burns E

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:in the UK, two-thirds of patients in general hospitals are older than 70, of whom half have dementia or delirium or both. Our objective was to explore doctors, nurses and allied health professionals' perceptions of their preparation to care for confused older patients on general hospital wards....

journal_title：Age and ageing

authors： Griffiths A,Knight A,Harwood R,Gladman JR

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Frailty is increasingly used to risk stratify older people, but across specialised services there is no standardised approach. The aim of this study was to assess if the Hospital Frailty Risk Score (HFRS) could describe outcomes for older people within English specialised services. DESIGN:A retrospective co...

journal_title：Age and ageing

authors： Imam T,Konstant-Hambling R,Fluck R,Hall N,Palmer J,Conroy S

更新日期：2020-09-08 00:00:00

abstract：:Falls pose a major threat to the well-being and quality of life of older people. Falls can result in fractures and other injuries, disability and fear and can trigger a decline in physical function and loss of autonomy. This article synthesises recent published findings on fall risk and mobility assessments and fall p...

journal_title：Age and ageing

authors： Lord SR,Close JCT

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:two common anti-diabetic treatments used are sitagliptin and sulphonylureas however evidence examining their comparative effectiveness in older people is limited. OBJECTIVE:to evaluate effectiveness of sitagliptin vs sulphonylureas when added to metformin in older (aged ≥75) vs younger people (18-75). DESI...

journal_title：Age and ageing

authors： Sharma M,Nazareth I,Petersen I

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. OBJECTIVE:to investigate the association of education with the onset of terminal decline in g...

journal_title：Age and ageing

authors： Terrera GM,Minett T,Brayne C,Matthews FE

更新日期：2014-01-01 00:00:00

abstract：:Ejection fraction was measured directly by a radionuclide method, and indirectly from systolic time intervals, in elderly patients in atrial fibrillation. Both methods show that the ejection fraction averages approximately 55% at mean ventricular rates of 50-70 beats/min and falls to 20% or below as mean rate increase...

journal_title：Age and ageing

authors： Caird FI,Williams BO

更新日期：1981-11-01 00:00:00

abstract：:This study aimed to determine the prevalence of the wish to die in elderly people and investigate the factors associated with it, in particular, whether factors other than depression contribute to the wish to die. Data were obtained from an Australian epidemiological survey of people aged 70 or more. Survey participan...

journal_title：Age and ageing

authors： Jorm AF,Henderson AS,Scott R,Korten AE,Christensen H,Mackinnon AJ

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVES:To determine the presentation, course and duration of delirium in hospitalized older people. DESIGN:Observational cohort study. SETTING:Inpatient surgical and medical wards at a university hospital. PARTICIPANTS:432 people over the age of 65. MEASUREMENTS:All participants were screened daily for confusio...

journal_title：Age and ageing

authors： Rudberg MA,Pompei P,Foreman MD,Ross RE,Cassel CK

更新日期：1997-05-01 00:00:00

abstract：:Prolonged head-up tilt is increasingly used as a diagnostic test for vasovagal syncope. Its sensitivity is reported to increase with the concurrent administration of intravenous isoprenaline. False-positive responses are common in young controls particularly following intravascular instrumentation. We studied the infl...

journal_title：Age and ageing

authors： McIntosh SJ,Lawson J,Kenny RA

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:There is little evidence about the utilization of healthcare services and disease recognition in the older population, which was urged to self-isolate during the COVID-19 lockdowns. OBJECTIVES:We aimed to describe the utilization of physician consultations, specialist referrals, hospital admissions, and the...

journal_title：Age and ageing

authors： Michalowsky B,Hoffmann W,Bohlken J,Kostev K

更新日期：2020-11-17 00:00:00

abstract：:A study was carried out to examine the prevalence of oropharyngeal and urinary tract colonization and to compare the colonizing bacteria with the strains causing nosocomial infections during patients' stays in a geriatric ward. Colonization with Gram-negative rods was not uncommon. Nosocomial infections frequently occ...

journal_title：Age and ageing

authors： Michielsen W,Vandevondele D,Verschraegen G,Claeys G,Afschrift M

更新日期：1993-05-01 00:00:00

abstract：Background:overactive bladder (OAB) is a common condition in older persons. Antimuscarinic treatment remains the mainstay of treatment of OAB but clinicians have been reluctant to prescribe this to older patients. This study examined efficacy and safety information from patients >65 in fesoterodine trials to reaffirm e...

journal_title：Age and ageing

authors： Wagg A,Arumi D,Herschorn S,Angulo Cuesta J,Haab F,Ntanios F,Carlsson M,Oelke M

更新日期：2017-07-01 00:00:00

abstract：:Fifty-eight carers and their dependents who received inpatient respite care were studied before and during the admission period. Although there was no observable improvement in the carers' emotional well-being the majority of the patients showed an improvement in functioning, particularly those who were being looked a...

journal_title：Age and ageing

authors： Homer AC,Gilleard CJ

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:to investigate the effectiveness of a pharmacy discharge plan in elderly hospitalized patients. DESIGN:randomized controlled trial. SUBJECTS AND SETTINGS:we randomized patients aged 75 years and older on four or more medicines who had been discharged from three acute general and one long-stay hospital to a...

journal_title：Age and ageing

authors： Nazareth I,Burton A,Shulman S,Smith P,Haines A,Timberal H

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:the organisation of long-term medicine and geriatric medicine has undergone many changes during the last 15 years. The aim of this study is to gain an overall perspective of the present organisation of geriatric medicine in Sweden. DESIGN:questionnaire survey. METHODS:The Swedish Society for Geriatric Medic...

journal_title：Age and ageing

authors： Akner G

更新日期：2004-07-01 00:00:00

abstract：:From a study of routine electrocardiography on 300 ill elderly patients in an acute geriatric unit, it is evident that the incidence of atrial fibrillation, ventricular extrasystoles, myocardial ischaemia and myocardial infarction is much higher than in the general population of similar age group. In females, the inci...

journal_title：Age and ageing

authors： Patel KP

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Therapists and nurses often use verbal instruction in the rehabilitation of mobility following stroke. This study aimed to determine whether performing a verbal cognitive task while walking adversely affected patients' balance and velocity. METHODS:There were two counterbalanced conditions: walking only and...

journal_title：Age and ageing

authors： Bowen A,Wenman R,Mickelborough J,Foster J,Hill E,Tallis R

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:vascular disease has been postulated to contribute to muscle dysfunction in old age. Previous studies examining the effects of cardiovascular drugs on muscle function have shown conflicting results. We therefore examined the association of angiotensin converting enzyme (ACE) inhibitor, thiazide and statin us...

journal_title：Age and ageing

authors： Witham MD,Syddall HE,Dennison E,Cooper C,McMurdo ME,Sayer AA

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Studies have raised concerns that medications with anticholinergic property have potential adverse effects on health outcomes. OBJECTIVES:The objective of this study is to examine the prospective relationships between total anticholinergic burden (ACB) from medications and mortality, and cardiovascular dise...

journal_title：Age and ageing

authors： Myint PK,Fox C,Kwok CS,Luben RN,Wareham NJ,Khaw KT

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:to provide evidence for predictors of recovery in instrumental activities of daily living (IADLs) among disabled older people living in the community. DESIGN:MRC CFAS recruited a sample of 13,004 individuals aged 65 years and above from five communities in the UK. Participants underwent a baseline interview ...

journal_title：Age and ageing

authors： Seidel D,Jagger C,Brayne C,Matthews FE,Cfas M

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:to assess the validity of the Direct Assessment of Functional Status (DAFS) performance-based functional scale for the staging of dementia severity by comparing it with established clinical, functional and cognitive scales. PATIENTS AND METHODS:93 consecutive Alzheimer's disease patients underwent DAFS. Soci...

journal_title：Age and ageing

authors： Zanetti O,Frisoni GB,Rozzini L,Bianchetti A,Trabucchi M

更新日期：1998-09-01 00:00:00

abstract：:The results reported here are from a 2-year follow-up study of 58 elderly patients in a continuing-care unit. Most of these patients were in a hyperosmolar state at the time of entry (mean plasma osmolality 304 +/- 8 mOsmol/kg). The survival of those patients with the highest osmolality (greater than 308 mOsmol/kg) wa...

journal_title：Age and ageing

authors： O'Neill PA,Faragher EB,Davies I,Wears R,McLean KA,Fairweather DS

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:to prevent the occurrence of weight loss during hospitalisation and following discharge by daily oral supplementation. DESIGN:in a prospective, randomised, controlled study of 80 patients aged 75 or more, and at risk of undernutrition based on their initial Mini Nutritional Assessment score, patients were ra...

journal_title：Age and ageing

authors： Gazzotti C,Arnaud-Battandier F,Parello M,Farine S,Seidel L,Albert A,Petermans J

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVES:Previous research has indicated that age-related medical or health conditions can affect driving performance in older adults but little, if any, research has examined the mechanisms through which health conditions affect driving difficulties in older adults. DESIGN:Cross-sectional, correlational study. SET...

journal_title：Age and ageing

authors： Tuokko HA,Rhodes RE,Dean R

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:fifteen percent of patients with Crohn's disease (CD) are elderly; they are less likely to have complications and more likely to have colonic disease. OBJECTIVE:to compare disease behaviour in patients with CD based on age at diagnosis. DESIGN:cross-sectional study. SETTING:tertiary referral centre. SUBJ...

journal_title：Age and ageing

authors： Quezada SM,Steinberger EK,Cross RK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:the oldest old (85+) pose complex medical challenges. Both underdiagnosis and overdiagnosis are claimed in this group. OBJECTIVE:to estimate diagnosis, prescribing and hospital admission prevalence from 2003/4 to 2011/12, to monitor trends in medicalisation. DESIGN AND SETTING:observational study of Clinic...

journal_title：Age and ageing

authors： Melzer D,Tavakoly B,Winder RE,Masoli JA,Henley WE,Ble A,Richards SH

更新日期：2015-01-01 00:00:00

abstract：:The effectiveness was compared of 'Classroom' Reality Orientation presented (1) once daily, in groups; (2) twice daily, in groups; and (3) once daily, individually. On a questionnaire measure of orientation all three versions produced significantly greater improvement than that found in an untreated control group, but...

journal_title：Age and ageing

authors： Johnson CH,McLaren SM,McPherson FM

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:There is a paucity of information about the use of antipsychotic medication in long-term care, especially among the oldest-old residents. OBJECTIVE:To analyse the factors associated with the use of antipsychotic medication among nonagenarian residents in long-term institutional care. DESIGN:A retrospective...

journal_title：Age and ageing

authors： Alanen HM,Finne-Soveri H,Noro A,Leinonen E

更新日期：2006-09-01 00:00:00

abstract：:Previous studies have suggested that up to a fifth of people over the age of 80 years may suffer severe dementia-like illnesses. This total population survey of over a thousand people over the age of 75 suggests that the prevalence of marked cognitive impairment is much less than expected. However, differences in the ...

journal_title：Age and ageing

authors： Clarke M,Lowry R,Clarke S

更新日期：1986-09-01 00:00:00