Association of age at diagnosis and Crohn's disease phenotype.

abstract：:One hundred and twenty-two consecutive patients admitted with acute stroke in a carotid distribution had venous blood taken for haematocrit (Hct), haemoglobin (Hb), white cell count (WCC) and urea estimations. Patients were followed for 12 weeks to determine the influence of haematocrit upon fatality. There were 96 pa...

journal_title：Age and ageing

authors： Gray CS,French JM,James OF,Bates D,Cartlidge NE

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:to explore the effect of ageing on renal function with cystatin C as the marker of glomerular filtration rate (GFR) in the general population without vascular disease or diabetes. DESIGN:a cross-sectional analysis of a healthy subset from the Good Aging in Skåne-cohort study representative of the...

journal_title：Age and ageing

authors： Werner KB,Elmståhl S,Christensson A,Pihlsgård M

更新日期：2014-05-01 00:00:00

abstract：:A simple random sample of older people composed of 215 men and 272 women aged 62 years and over was examined in Edinburgh in 1968-9. After one year, 86 per cent of the men and 79 per cent of the women were re-examined; 7 per cent of the men and 4 per cent of the women had died and the remainder were not re-examined fo...

journal_title：Age and ageing

authors： Milne JS,Chopin JM

更新日期：1975-08-01 00:00:00

abstract：OBJECTIVES:this study investigated the prospective associations of accelerometer assessed daily steps with subsequent depressive symptoms in older adults. METHODS:a 2-year prospective study was performed in the community. A total of 285 older adults ≥65 years (mean age = 74.5) attended the baseline assessment in 2012....

journal_title：Age and ageing

authors： Hsueh MC,Stubbs B,Lai YJ,Sun CK,Chen LJ,Ku PW

更新日期：2020-09-25 00:00:00

abstract：CASE REPORTS:two elderly patients (aged 70 and 80 years) presented with severe back pain and restriction of spinal movements. Inflammatory markers were raised and in each case computed tomography findings confirmed infective discitis. One patient improved with antibiotics but the second developed paraplegia, a recogniz...

journal_title：Age and ageing

authors： Goel V,Young JB,Patterson CJ

更新日期：2000-09-01 00:00:00

abstract：:Four hundred and fifty patients aged 75 years or older were followed up after discharge from an accident and emergency department. Forty-three per cent of all patients experienced some loss of functional independence. A small number, 5.6%, were readmitted to hospital within 14 days. This group were significantly less ...

journal_title：Age and ageing

authors： Rowland K,Maitra AK,Richardson DA,Hudson K,Woodhouse KW

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Multi-morbidity and polypharmacy increase the risk of non-trivial adverse drug reactions (ADRs) in older people during hospitalization. Despite this, there are no established interventions for hospital-acquired ADR prevention. METHODS:We undertook a pragmatic, multi-national, parallel arm prospective random...

journal_title：Age and ageing

authors： O'Mahony D,Gudmundsson A,Soiza RL,Petrovic M,Jose Cruz-Jentoft A,Cherubini A,Fordham R,Byrne S,Dahly D,Gallagher P,Lavan A,Curtin D,Dalton K,Cullinan S,Flanagan E,Shiely F,Samuelsson O,Sverrisdottir A,Subbarayan S,V

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:arterial stiffening is a marker of vascular ageing and an independent risk factor for cardiovascular disease. A potential mechanism linking cardiovascular disease to chronic kidney disease might be the change in arterial elasticity. We aim to determine the association between renal function and arterial stif...

journal_title：Age and ageing

authors： Sedaghat S,Dawkins Arce FG,Verwoert GC,Hofman A,Ikram MA,Franco OH,Dehghan A,Witteman JC,Mattace-Raso F

更新日期：2014-11-01 00:00:00

abstract：:Explicit criteria, such as the STOPP/START criteria, are increasingly used both in clinical practice and in research to identify potentially inappropriate prescribing in older people. In an article on the STOPP/START criteria version 2, O'Mahony et al have pointed out the advantages of developing computerised criteria...

journal_title：Age and ageing

authors： Anrys P,Boland B,Degryse JM,De Lepeleire J,Petrovic M,Marien S,Dalleur O,Strauven G,Foulon V,Spinewine A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:chronic knee pain is still considered a fairly benign disease by many, an 'unavoidable' consequence of ageing. This passive acceptance may be unnecessarily exposing older people to disability and serious co-morbidity. The aim of this study was to determine the disease burden associated with chronic knee pain...

journal_title：Age and ageing

authors： Fransen M,Su S,Harmer A,Blyth FM,Naganathan V,Sambrook P,Le Couteur D,Cumming RG

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:the oldest old (85+) pose complex medical challenges. Both underdiagnosis and overdiagnosis are claimed in this group. OBJECTIVE:to estimate diagnosis, prescribing and hospital admission prevalence from 2003/4 to 2011/12, to monitor trends in medicalisation. DESIGN AND SETTING:observational study of Clinic...

journal_title：Age and ageing

authors： Melzer D,Tavakoly B,Winder RE,Masoli JA,Henley WE,Ble A,Richards SH

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Using Newcastle 85+ Study data, we investigated transitions between frailty states from age 85 to 90 years and whether multi-morbidities and socioeconomic status (SES) modify transitions. METHODS:The Newcastle 85+ Study is a prospective, longitudinal cohort study of all people born in 1921 in Newcastle and ...

journal_title：Age and ageing

authors： Mendonça N,Kingston A,Yadegarfar M,Hanson H,Duncan R,Jagger C,Robinson L

更新日期：2020-10-23 00:00:00

abstract：Objective:to describe differences in care and 30-day mortality of patients admitted with hip fracture on weekends (Saturday-Sunday) compared to weekdays (Monday-Friday), and their relationship to the organisation of care. Methods:data came from the National Hip Fracture Database (NHFD) linked to ONS mortality data on ...

journal_title：Age and ageing

authors： Neuburger J,Currie C,Wakeman R,Georghiou T,Boulton C,Johansen A,Tsang C,Wilson H,Cromwell DA,van der Meulen J

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:Socio-economic differences in mobility disability prevalence in old age have been reported from the US and Europe. Brazil is characterised by gross socio-economic inequalities, but there have been no previous national data on disability prevalence. AIM:This study aimed to estimate disability rates and exp...

journal_title：Age and ageing

authors： Melzer D,Parahyba MI

更新日期：2004-05-01 00:00:00

abstract：:Fifty-eight carers and their dependents who received inpatient respite care were studied before and during the admission period. Although there was no observable improvement in the carers' emotional well-being the majority of the patients showed an improvement in functioning, particularly those who were being looked a...

journal_title：Age and ageing

authors： Homer AC,Gilleard CJ

更新日期：1994-07-01 00:00:00

abstract：:Drug compliance was assessed amongst all 91 patients attending a psychogeriatric day hospital during July 1988. Of the 86 patients taking medication, the 57 functionally and 29 organically ill patients were interviewed at home, the latter with their carers. A disparity in results was shown when compliance was measured...

journal_title：Age and ageing

authors： Rosenvinge HP,Groarke EP,Bradshaw JW

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:while it is well established that individual patient preferences regarding cardiopulmonary resuscitation (CPR) may change with time, the stability of population preferences, especially during periods of social and economic change, has received little attention. OBJECTIVE:to elicit the resuscitation preferen...

journal_title：Age and ageing

authors： Cotter PE,Simon M,Quinn C,O'Keeffe ST

更新日期：2009-03-01 00:00:00

abstract：:We present two cases of acute hepatotoxicity associated with elevated paracetamol (acetaminophen) levels in older patients. Both patients were receiving a standard European dose of oral paracetamol (2 × 500 mg QDS) with no risk factors for slowed metabolism (weight <50 kg, interacting medications, hepatic enzyme induc...

journal_title：Age and ageing

authors： Ging P,Mikulich O,O'Reilly KM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:delirium is a frequent complication of hospital admission for older people and can be reduced by multicomponent interventions, but implementation and delivery of such interventions is challenging. OBJECTIVE:to investigate fidelity to the prevention of delirium system of care within a multicentre, pragmatic,...

journal_title：Age and ageing

authors： Smith J,Green J,Siddiqi N,Inouye SK,Collinson M,Farrin A,Young J

更新日期：2020-07-01 00:00:00

abstract：:The medical histories of 178 colorectal cancer patients were studied retrospectively from hospital records. The average age at the time of diagnosis was 71 years. Visible loss of blood or anaemia were the commonest features. The mean time from first symptom to first medical consultation was 82.8 days. Men under 65 yea...

journal_title：Age and ageing

authors： Kemppainen M,Räihä I,Rajala T,Sourander L

更新日期：1993-07-01 00:00:00

abstract：:The results reported here are from a 2-year follow-up study of 58 elderly patients in a continuing-care unit. Most of these patients were in a hyperosmolar state at the time of entry (mean plasma osmolality 304 +/- 8 mOsmol/kg). The survival of those patients with the highest osmolality (greater than 308 mOsmol/kg) wa...

journal_title：Age and ageing

authors： O'Neill PA,Faragher EB,Davies I,Wears R,McLean KA,Fairweather DS

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The number of new world records has decreased substantially in most athletic events in recent years. There has been enormous growth in participation at Masters events, and older athletes have been competing at the highest levels with much younger athletes. However, the progression of athletic performance ove...

journal_title：Age and ageing

authors： Akkari A,Machin D,Tanaka H

更新日期：2015-07-01 00:00:00

abstract：:Postural control is no longer considered simply a summation of static reflexes but, rather, a complex skill based on the interaction of dynamic sensorimotor processes. The two main functional goals of postural behaviour are postural orientation and postural equilibrium. Postural orientation involves the active alignme...

journal_title：Age and ageing

authors： Horak FB

更新日期：2006-09-01 00:00:00

abstract：:Sporadic Creutzfeld-Jakob disease (CJD) is a rare neurodegenerative disorder. It is uniformly fatal. Clinical signs include myoclonus, visual disturbances, cerebellar ataxia, akinetic mutism and pyramidal/extrapyramidal signs in addition to a rapidly progressive dementia. Premortem diagnosis is challenging due to the ...

journal_title：Age and ageing

authors： Podger H,Ipe A

更新日期：2020-04-27 00:00:00

abstract：Background:there is growing consensus around the importance of population level approaches which seek to improve public knowledge and awareness of dementia. Aim:to assess knowledge of the relationship between dementia and ageing, and of the risk and protective factors associated with it, among the general public in Ir...

journal_title：Age and ageing

authors： Glynn RW,Shelley E,Lawlor BA

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Dementia is a predictor of death and institutionalization. It is less clear if variations in cognition within the normal range predict adverse outcomes. OBJECTIVE:To determine if variation at the high end of cognitive test scores predicts mortality or institutionalization, independent of the effect of poten...

journal_title：Age and ageing

authors： St John PD,Montgomery PR,Kristjansson B,McDowell I

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:To examine whether in older people perceived age is associated with risk of total mortality independent of chronological age. DESIGN:Prospective population-based study (Evergreen project) with mortality surveillance for 13 years after the baseline. SETTING:Face-to-face interview among community-dwelling re...

journal_title：Age and ageing

authors： Uotinen V,Rantanen T,Suutama T

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:epidemiological studies of Alzheimer's disease and aluminium intake have focused on aluminium in drinking water. There have been no studies investigating the relation between the disease and the consumption of foods containing large amounts of aluminium additives. OBJECTIVES:to conduct a pilot study to dete...

journal_title：Age and ageing

authors： Rogers MA,Simon DG

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:the STOPP criteria advise against the use of long-acting benzodiazepines (LBs). OBJECTIVE:to study whether LBs are associated with a higher fall risk than short-acting benzodiazepines (SBs) (elimination half-life ≤ 10 h). METHODS:we used base-line data and prospective fall follow-up from the Longitudinal A...

journal_title：Age and ageing

authors： de Vries OJ,Peeters G,Elders P,Sonnenberg C,Muller M,Deeg DJ,Lips P

更新日期：2013-11-01 00:00:00

abstract：:Among 352 residents of a home for the elderly, who were fully mobile and devoid of most predisposing factors for bacteriuria, 19% of men and 27% of women had two positive cultures within two months. Positive conversion at one year among men and women negative at entry was 11% and 23% respectively, negative conversion ...

journal_title：Age and ageing

authors： Kasviki-Charvati P,Drolette-Kefakis B,Papanayiotou PC,Dontas AS

更新日期：1982-08-01 00:00:00