A preliminary study of dietary aluminium intake and risk of Alzheimer's disease.

Abstract:

BACKGROUND:epidemiological studies of Alzheimer's disease and aluminium intake have focused on aluminium in drinking water. There have been no studies investigating the relation between the disease and the consumption of foods containing large amounts of aluminium additives. OBJECTIVES:to conduct a pilot study to determine whether dietary intake of aluminium additives differs in individuals with and without Alzheimer's disease. DESIGN:matched case-control study. Controls were matched to cases on age, gender and date of admission to the centre. SETTING:Syracuse, New York, USA. SUBJECTS:46 participants comprising 23 matched sets. METHODS:residents of the Loretto Geriatric Center with and without newly-diagnosed Alzheimer's disease were selected. Next-of-kin were asked to complete information on the resident's medical history, lifestyle behaviour and dietary intake before admission to the centre. An expanded form of the Health Habits and History Questionnaire was used to determine dietary intake. Consumption of foods containing elevated levels of aluminium additives was compared between cases and controls. RESULTS:the crude odds ratio for daily intake of foods containing high levels of aluminium was 2.0 and, when adjusted for covariates, was 8.6 (P=0.19). Intake of pancakes, waffles, biscuits, muffins, cornbread and/or corn tortillas differed significantly (P=0.025) between cases and controls. Adjusted odds ratios were also elevated for grain product desserts, American cheese, chocolate pudding or beverages, salt and chewing gum. However, the odds ratio was not elevated for tea consumption. CONCLUSION:past consumption of foods containing large amounts of aluminium additives differed between people with Alzheimer's disease and controls, suggesting that dietary intake of aluminium may affect the risk of developing this disease. Larger studies are warranted to corroborate or refute these preliminary findings.

journal_name

Age Ageing

journal_title

Age and ageing

authors

Rogers MA,Simon DG

doi

10.1093/ageing/28.2.205

subject

Has Abstract

pub_date

1999-03-01 00:00:00

pages

205-9

issue

2

eissn

0002-0729

issn

1468-2834

journal_volume

28

pub_type

杂志文章
  • Risk of imbalance in elderly people with impaired hearing or vision.

    abstract::We evaluated the effect of impaired hearing and vision on balance in a sample of 977 elderly people residing in the community. Of the sample, 21% reported balance problems, 27% vision problems, and 30% hearing problems. The increased relative risk for balance problems was 1.7 for each 10-year age increment. Women were...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/18.1.31

    authors: Gerson LW,Jarjoura D,McCord G

    更新日期:1989-01-01 00:00:00

  • Neighbourhood deprivation and incident mobility disability in older adults.

    abstract:OBJECTIVE:to assess whether incident mobility disability and neighbourhood deprivation in older people are associated independent of the effects of individual socio-economic status, health behaviours and health status. METHODS:prospective cohort study with a 2-year follow-up. SETTING:the English Longitudinal Study of...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afn092

    authors: Lang IA,Llewellyn DJ,Langa KM,Wallace RB,Melzer D

    更新日期:2008-07-01 00:00:00

  • Ageism in the management of lung cancer.

    abstract:BACKGROUND:age-related differences in the treatment of lung cancer patients have been reported in the past, but most previous studies have not recorded case-mix factors, nor have they studied the impact of such ageism on survival. METHODS:a questionnaire-based study of diagnostic and case-mix factors was carried out a...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/32.2.171

    authors: Peake MD,Thompson S,Lowe D,Pearson MG,Participating Centres.

    更新日期:2003-03-01 00:00:00

  • The reliability and predictive accuracy of the falls risk for older people in the community assessment (FROP-Com) tool.

    abstract:BACKGROUND:the Falls Risk for Older People in the Community assessment (FROP-Com) tool was designed for use in targeted multi-factorial falls prevention programmes. It fills the gap between the short screening tools and the longer assessment tools, e.g. the physiological profile assessment (PPA). The aim of this study ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afn129

    authors: Russell MA,Hill KD,Blackberry I,Day LM,Dharmage SC

    更新日期:2008-11-01 00:00:00

  • Shared genetic influence on frailty and chronic widespread pain: a study from TwinsUK.

    abstract:Introduction:frailty is an increased vulnerability to adverse health outcomes, across multiple physiological systems, with both environmental and genetic drivers. The two most commonly used measures are Rockwood's frailty index (FI) and Fried's frailty phenotype (FP). Material and methods:the present study included 36...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afx122

    authors: Livshits G,Ni Lochlainn M,Malkin I,Bowyer R,Verdi S,Steves CJ,Williams FMK

    更新日期:2018-01-01 00:00:00

  • The association of ageing with calcium active hormone status in men.

    abstract::We measured calcium regulating hormones and bone mineral density (BMD) in 66 men (aged 24-88 years). Vitamin D (1,25(OH)2D) does not vary with age, parathyroid hormone (PTH) increases after the age of 65 (p < 0.01) together with a parallel increase in urinary (r = 0.46, p < 0.05) and nephrogenic cAMP (r = 0.63, p < 0....

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/23.2.127

    authors: Ravaglia G,Forti P,Pratelli L,Maioli F,Scali CR,Bonini AM,Tedioli S,Marasti N,Pizzoferrato A,Gasbarrini G

    更新日期:1994-03-01 00:00:00

  • Care homes and COVID-19 in Hong Kong: how the lessons from SARS were used to good effect.

    abstract::In Hong Kong, about 15% of older people (aged 80 and above) live in care homes, one of the highest proportions in the world. During the spread of severe acute respiratory syndrome in 2003, the crude fatality rate for older people in care homes that were infected was 72%. After taking the advice of a team of internatio...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afaa234

    authors: Chow L

    更新日期:2021-01-08 00:00:00

  • Inhaled therapy in elderly COPD patients; time for re-evaluation?

    abstract:OBJECTIVE:chronic obstructive pulmonary disease (COPD) prevalence steadily increases with age. However, the effectiveness of inhaled therapy in the elderly COPD population has rarely been formally evaluated. We studied a group of elderly patients with COPD with a range of severity, selected from one General Practice re...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afl174

    authors: Jarvis S,Ind PW,Shiner RJ

    更新日期:2007-03-01 00:00:00

  • Proximity to death is associated with frequency of GP contacts in the oldest old: the Leiden 85-plus study.

    abstract:BACKGROUND:the relationship between proximity to death and the amount of care provided by general practitioners (GPs) is largely unknown. OBJECTIVE:to examine the influence of the proximity to death on the frequency and length of GP contacts in the oldest old. STUDY DESIGN:this population-based follow-up study includ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afs062

    authors: Blom JW,Lemmens SP,Assendelft WJ,Eekhof JA,Gussekloo J

    更新日期:2012-11-01 00:00:00

  • Doege-Potter syndrome: hypoglycaemic coma in a 90-year old due to a solitary fibrous tumour.

    abstract::Solitary fibrous tumour of the pleura (SFTP) is a rare primary tumour of the pleura associated with 4% of cases with a paraneoplastic hypoglycaemia, termed Doege-Potter syndrome (DPS). We report a case of DPS presenting with severe coma in a 90-year-old woman. The cause was a malignant SFTP treated with surgical resec...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afw221

    authors: Avramenko A,Lahjibi-Paulet H,Gibault L,Roussel A,Grand B,Le Pimpec-Barthes F

    更新日期:2017-05-01 00:00:00

  • Clinical correlates of sway in old age--sensory modalities.

    abstract::Sway has been measured by Wright's Ataxiameter in 151 frail elderly and five young subjects, and compared with various sensory modalities. There is a close relationship between increased sway and impaired vibration sense in the legs. No correlations emerged with proprioception but this may reflect the imprecision of t...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/11.1.1

    authors: Brocklehurst JC,Robertson D,James-Groom P

    更新日期:1982-02-01 00:00:00

  • Caring for a dying spouse at the end of life: 'It's one of the things you volunteer for when you get married': a qualitative study of the oldest carers' experiences.

    abstract:BACKGROUND:older people aged 80 and over are increasingly providing end-of-life care to spouses at home and often do so for long periods of time, while also trying to manage their own illnesses and disabilities. Little of the research on older spousal carers has focussed on the oldest carers; hence, the needs of this p...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afw047

    authors: Turner M,King C,Milligan C,Thomas C,Brearley SG,Seamark D,Wang X,Blake S,Payne S

    更新日期:2016-05-01 00:00:00

  • Blood pressure rhythm and prevalence of vascular events in hypertensive subjects.

    abstract:OBJECTIVES:To evaluate the influence of age on the day-night blood pressure rhythm and on the prevalence of vascular events in those whose systolic blood pressure (SBP) fell by <10% overnight (non-dippers). DESIGN:Cross-sectional observational cohort study. SETTING:Outpatient hypertension clinic. PARTICIPANTS:419 Hy...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/28.1.23

    authors: Di Iorio A,Marini E,Lupinetti M,Zito M,Abate G

    更新日期:1999-01-01 00:00:00

  • Socio-demographic correlates of mobility disability in older Brazilians: results of the first national survey.

    abstract:INTRODUCTION:Socio-economic differences in mobility disability prevalence in old age have been reported from the US and Europe. Brazil is characterised by gross socio-economic inequalities, but there have been no previous national data on disability prevalence. AIM:This study aimed to estimate disability rates and exp...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afh075

    authors: Melzer D,Parahyba MI

    更新日期:2004-05-01 00:00:00

  • Duodenal ulcer disease in the elderly: a retrospective study.

    abstract::A retrospective study was performed of 163 patients aged 65 years and over with a diagnosis of duodenal ulceration admitted to one Health District over a period of six years. Eighty per cent of the patients were admitted with acute complications, 50% bled and 30% were perforated. A large proportion of these patients w...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/14.4.225

    authors: Watson RJ,Hooper TL,Ingram G

    更新日期:1985-07-01 00:00:00

  • Development of the nursing home Resident Assessment Instrument in the USA.

    abstract:BACKGROUND:the nursing home Resident Assessment Instrument (RAI) includes a set of core assessment items, known as the Minimum Data Set (MDS), for assessment and care screening and more detailed Resident Assessment Protocols in 18 areas that represent common problem areas or risk factors for nursing home residents. Its...

    journal_title:Age and ageing

    pub_type: 杂志文章,评审

    doi:10.1093/ageing/26.suppl_2.19

    authors: Hawes C,Morris JN,Phillips CD,Fries BE,Murphy K,Mor V

    更新日期:1997-09-01 00:00:00

  • Best practice guidelines for the management of frailty: a British Geriatrics Society, Age UK and Royal College of General Practitioners report.

    abstract:UNLABELLED:Older people are majority users of health and social care services in the UK and internationally. Many older people who access these services have frailty, which is a state of vulnerability to adverse outcomes. The existing health care response to frailty is mainly secondary care-based and reactive to the ac...

    journal_title:Age and ageing

    pub_type: 杂志文章,实务指引,评审

    doi:10.1093/ageing/afu138

    authors: Turner G,Clegg A,British Geriatrics Society.,Age UK.,Royal College of General Practioners.

    更新日期:2014-11-01 00:00:00

  • Is physical activity protective against hip fracture in frail older people?

    abstract:BACKGROUND:there is limited evidence of a protective effect of physical activity in preventing hip fractures among older people living in institutions and in those aged 80 or over. OBJECTIVE:to examine the relationship between physical activity and risk of hip fracture in frail older people. DESIGN:a case-control stu...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/30.3.262

    authors: Norton R,Galgali G,Campbell AJ,Reid IR,Robinson E,Butler M,Gray H

    更新日期:2001-05-01 00:00:00

  • The discharge of elderly patients from an accident and emergency department: functional changes and risk of readmission.

    abstract::Four hundred and fifty patients aged 75 years or older were followed up after discharge from an accident and emergency department. Forty-three per cent of all patients experienced some loss of functional independence. A small number, 5.6%, were readmitted to hospital within 14 days. This group were significantly less ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/19.6.415

    authors: Rowland K,Maitra AK,Richardson DA,Hudson K,Woodhouse KW

    更新日期:1990-11-01 00:00:00

  • Geriatric medicine in Sweden: a study of the organisation, staffing and care production in 2000-2001.

    abstract:OBJECTIVE:the organisation of long-term medicine and geriatric medicine has undergone many changes during the last 15 years. The aim of this study is to gain an overall perspective of the present organisation of geriatric medicine in Sweden. DESIGN:questionnaire survey. METHODS:The Swedish Society for Geriatric Medic...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afh115

    authors: Akner G

    更新日期:2004-07-01 00:00:00

  • Infective discitis as an uncommon but important cause of back pain in older people.

    abstract:CASE REPORTS:two elderly patients (aged 70 and 80 years) presented with severe back pain and restriction of spinal movements. Inflammatory markers were raised and in each case computed tomography findings confirmed infective discitis. One patient improved with antibiotics but the second developed paraplegia, a recogniz...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/29.5.454

    authors: Goel V,Young JB,Patterson CJ

    更新日期:2000-09-01 00:00:00

  • The association between Healthy Eating Index-2005 scores and disability among older Americans.

    abstract:BACKGROUND:several studies examining diet and functional status of individuals have focused on single nutrients or food groups. Studies examining the relationship between diet and health have increasingly witnessed a shift in focus from single nutrients to overall diet quality. The objective of this study was to examin...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afr158

    authors: Xu B,Houston D,Locher JL,Zizza C

    更新日期:2012-05-01 00:00:00

  • A general population survey of rest cramps.

    abstract::Two hundred and eighteen subjects, out of 250 individuals taken from a general practice register, returned completed questionnaires giving details about rest cramps, and a further 15 were contacted by telephone. The overall prevalence of rest cramps in the survey population was 37%. The symptom was more prevalent in o...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/23.5.418

    authors: Naylor JR,Young JB

    更新日期:1994-09-01 00:00:00

  • Validation of the 6-Item Cognitive Impairment Test and the 4AT test for combined delirium and dementia screening in older Emergency Department attendees.

    abstract:Background:screening for cognitive impairment in Emergency Department (ED) requires short, reliable tools. Objective:to validate the 4AT and 6-Item Cognitive Impairment Test (6-CIT) for ED dementia and delirium screening. Design:diagnostic accuracy study. Setting/subjects:attendees aged ≥70 years in a tertiary care ...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afx149

    authors: O'Sullivan D,Brady N,Manning E,O'Shea E,O'Grady S,O 'Regan N,Timmons S

    更新日期:2018-01-01 00:00:00

  • The association between life course socioeconomic position and life satisfaction in different welfare states: European comparative study of individuals in early old age.

    abstract:BACKGROUND:whether socioeconomic position over the life course influences the wellbeing of older people similarly in different societies is not known. OBJECTIVE:to investigate the magnitude of socioeconomic inequalities in life satisfaction among individuals in early old age and the influence of the welfare state regi...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/afu004

    authors: Niedzwiedz CL,Katikireddi SV,Pell JP,Mitchell R

    更新日期:2014-05-01 00:00:00

  • Stroke knowledge and awareness: an integrative review of the evidence.

    abstract:BACKGROUND:the recognition of stroke symptoms by the public and activation of the emergency medical services (EMS) are the most important factors in instigating pre-hospital stroke care. Studies have suggested that poor recognition of the warning signs of stroke is the main cause of delay in accessing the EMS. METHODS...

    journal_title:Age and ageing

    pub_type: 杂志文章,评审

    doi:10.1093/ageing/afp196

    authors: Jones SP,Jenkinson AJ,Leathley MJ,Watkins CL

    更新日期:2010-01-01 00:00:00

  • Slicing the health service cake: the Islington study.

    abstract:BACKGROUND:Little is known about the factors that are associated with receipt of care in older people. This study aims to describe the pattern and predictors of service usage, by a representative sample of people aged 65 and over. METHOD:We assessed psychiatric and physical morbidity, formal and informal care and pres...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/31.6.445

    authors: Nelson T,Livingston G,Knapp M,Manela M,Kitchen G,Katona C

    更新日期:2002-11-01 00:00:00

  • Patterns of mortality in homes for the elderly.

    abstract::High rates of mortality are an abiding feature of homes for the elderly. Almost a fifth (19.2%) of a cohort of 6947 residents died in the 12 months following initial assessment. Survival rates vary widely, however, for different groups within the residential population. Using data from a longitudinal study of 175 home...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/12.3.240

    authors: Booth T,Phillips D,Barritt A,Berry S,Martin DN,Melotte C

    更新日期:1983-08-01 00:00:00

  • Older people in accident and emergency departments.

    abstract::Older people attend accident and emergency departments more frequently than younger people. However, most assessments indicate that this higher level of use is appropriate and is the result of more serious injury and illness among this population. Older patients discharged from accident and emergency departments are f...

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/30.suppl_3.3

    authors: Burns E

    更新日期:2001-08-01 00:00:00

  • Preparation to care for confused older patients in general hospitals: a study of UK health professionals.

    abstract:BACKGROUND AND OBJECTIVE:in the UK, two-thirds of patients in general hospitals are older than 70, of whom half have dementia or delirium or both. Our objective was to explore doctors, nurses and allied health professionals' perceptions of their preparation to care for confused older patients on general hospital wards....

    journal_title:Age and ageing

    pub_type: 杂志文章

    doi:10.1093/ageing/aft171

    authors: Griffiths A,Knight A,Harwood R,Gladman JR

    更新日期:2014-07-01 00:00:00